Homology modeling of a novel epoxide hydrolase (EH) from Aspergillus niger SQ-6: Structure-activity relationship in expoxides inhibiting EH activity

Journal of Molecular Modeling

Volumn 15, Issue 9, 2009, Pages 1125-1132

  Luo, Quan ^a   Yao, Yuan ^a   Han, Wei Wei ^a   Zhou, Yi Han ^a   Li, Ze Sheng ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Enantio selectivity; Epoxide hydrolase; Homology modeling; Molecular docking; sqEH

Indexed keywords

ASPARAGINE; EPOXIDE HYDROLASE; GLUTAMIC ACID; HISTIDINE; HYDROLASE INHIBITOR; OXYGEN; PHENYLALANINE; PROLINE; TRYPTOPHAN; WATER;

ARTICLE; ASPERGILLUS NIGER; BINDING AFFINITY; CATALYSIS; ENZYME ACTIVITY; ENZYME STRUCTURE; HYDROGEN BOND; HYDROLYSIS; HYDROPHOBICITY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; ASPERGILLUS NIGER; BINDING SITES; ENZYME INHIBITORS; EPOXIDE HYDROLASES; MODELS, CHEMICAL; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

ASPERGILLUS NIGER;

EID: 67849119579     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-009-0466-5     Document Type: Article

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