Ruthenium-catalyzed cross-coupling of tertiary propargyl alcohols with ω-alkynenitriles: A regio- and stereoselective surrogate for an aldol condensation

Journal of the American Chemical Society

Volumn 131, Issue 2, 2009, Pages 420-421

  Trost, Barry M ^a   Maulide, Nuno ^a   Rudd, Michael T ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOL CONDENSATION; ATOM ECONOMY; CROSS COUPLING REACTIONS; CROSS-COUPLING; DIENONES; FUNCTIONALIZED; PROPARGYL ALCOHOL; SINGLE-STEP; STEREO-SELECTIVE;

ACETYLENE; RUTHENIUM;

FUNCTIONAL GROUPS;

ALCOHOL; ORGANOMETALLIC COMPOUND; RUTHENIUM;

ALDOL REACTION; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CROSS COUPLING REACTION; ISOMERIZATION; STEREOCHEMISTRY;

EID: 67849113778     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja8077686     Document Type: Article

References (27)

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22. Slow addition of the propargyl alcohol component via syringe pump techniques or similar attempts at minimizing the effective concentration of the propargyl alcohol in solution did not provide significant improvement either.
23. 6.
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25. No dimerization of the cyanoalkyne was observed.
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