Tryptophan depletion in bipolar mania: Reduction of metabolic imbalance by administration according to body weight?

Bipolar Disorders

Volumn 11, Issue 5, 2009, Pages 557-558

  Zepf, Florian D ^a,b,c   Wöckel, Lars ^a,b   Herpertz Dahlmann, Beate ^a,b   Poustka, Fritz ^c   Freitag, Christine M ^c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b JARA TRANSLATIONAL BRAIN MEDICINE   (Germany)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; AMINO ACID DERIVATIVE; CHROMOGRANIN A; MOJA DE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINIC ACID; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; BIPOLAR MANIA; BODY WEIGHT; DRUG BLOOD LEVEL; DRUG SAFETY; DRUG TOLERABILITY; ENZYME METABOLISM; HUMAN; KIDNEY FUNCTION TEST; LETTER; METABOLIC DISORDER; NUTRITIONAL REQUIREMENT; PATIENT MONITORING; PRIORITY JOURNAL; PROTEIN DIET; RAPID TRYPTOPHAN DEPLETION; TREATMENT RESPONSE;

BIPOLAR DISORDER; BODY WEIGHT; DIET, REDUCING; HUMANS; METABOLIC DISEASES; TRYPTOPHAN;

EID: 67749144001     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/j.1399-5618.2009.00725.x     Document Type: Letter

References (9)

1. Young SN. Rapid tryptophan depletion as a treatment for acute mania: safety and mechanism of the therapeutic effect. Bipolar Disord 2008; 10: 850-851.
2. Applebaum J, Bersudsky Y, Klein E. Rapid tryptophan depletion as a treatment for acute mania: A double-blind, pilot-controlled study. Bipolar Disord 2007; 9: 884-887.
3. Zepf FD, Wockel L, Poustka F, Holtmann M. Diminished 5-HT functioning in CBCL pediatric bipolar disorder-profiled ADHD patients versus normal ADHD: Susceptibility to rapid tryptophan depletion influences reaction time performance. Hum Psychopharmacol 2008; 23: 291-299.
4. Zepf FD, Holtmann M, Stadler C et al. Diminished serotonergic functioning in hostile children with ADHD: Tryptophan depletion increases behavioural inhibition. Pharmacopsychiatry 2008; 41: 60-65.
5. Zepf FD, Wockel L, Poustka F, Holtmann M. Dietary tryptophan depletion according to body weight - a new treatment option in acute mania? Med Hypotheses 2008; 72: 47-48.
6. Zepf FD, Stadler C, Demisch L, Schmitt M, Landgraf M, Poustka F. Serotonergic functioning and trait-impulsivity in attention-deficit/ hyperactivity-disordered boys (ADHD): Influence of rapid tryptophan depletion. Hum Psychopharmacol 2008; 23: 43-51.
7. Zepf FD, Poustka F. 5-HT functioning and aggression in children with ADHD and disruptive behavior disorders. Hum Psychopharmacol 2008; 23: 438.
8. Stadler C, Zepf FD, Demisch L, Schmitt M, Landgraf M, Poustka F. Influence of rapid tryptophan depletion on laboratory-provoked aggression in children with ADHD. Neuropsychobiology 2007; 56: 104-110.
9. Zepf FD, Holtmann M, Stadler C, Wockel L, Poustka F. Reduced serotonergic functioning changes heart rate in ADHD. J Neural Transm 2009; 116: 105-108.