Prebiotics, probiotics, synbiotics in surgery-Are they only trendy, truly effective or even dangerous?

Langenbeck's Archives of Surgery

Volumn 394, Issue 3, 2009, Pages 547-555

  Rayes, Nada ^a   Seehofer, Daniel ^a   Neuhaus, Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Abdominal surgery; Bacterial infection; Prebiotics; Probiotics; Synbiotics

Indexed keywords

BETA GLUCAN; BIO THREE; ECOLOGIC 641; FRUCTOSE OLIGOSACCHARIDE; GALACTOSE OLIGOSACCHARIDE; HYDROXYMETHYLCELLULOSE; INULIN; MALTODEXTRIN; NEOMYCIN; PECTIN; PREBIOTIC AGENT; PROBIOTIC AGENT; PROVIVA; STARCH; SYNBIOTIC 2000; SYNBIOTIC AGENT; TREVIS; UNCLASSIFIED DRUG; YAKULT 400; YAKULT BL; YOGHURT;

ABDOMINAL SURGERY; ACUTE PANCREATITIS; BACILLUS PUMILUS; BACTERIAL INFECTION; BACTERIAL TRANSLOCATION; BIFIDOBACTERIUM ANIMALIS; BIFIDOBACTERIUM BREVE; CLINICAL TRIAL; CLOSTRIDIUM BUTYRICUM; COLORECTAL SURGERY; DRUG EFFICACY; DRUG SAFETY; ENTERIC FEEDING; ENTEROBACTERIACEAE; ENTEROCOCCUS FAECALIS; HUMAN; INFECTIOUS COMPLICATION; INTESTINE PREPARATION; LACTOBACILLUS; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS BIFIDUS; LACTOBACILLUS BULGARICUS; LACTOBACILLUS CASEI; LACTOBACILLUS DELBRUECKII; LACTOBACILLUS PARACASEI; LACTOBACILLUS PLANTARUM; LACTOBACILLUS SALIVARIUS; LACTOCOCCUS LACTIS; LEUCONOSTOC MESENTEROIDES; LIVER SURGERY; LIVER TRANSPLANTATION; MORTALITY; NONHUMAN; OAT; PANCREAS SURGERY; PARENTERAL NUTRITION; PEDIOCOCCUS; PRIORITY JOURNAL; REVIEW; SEPSIS; STREPTOCOCCUS THERMOPHILUS; TREATMENT DURATION; TREATMENT OUTCOME; TREND STUDY; UNSPECIFIED SIDE EFFECT;

ABDOMEN; ANIMALS; BACTERIAL INFECTIONS; CROSS INFECTION; HUMANS; PROBIOTICS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS;

EID: 67749130830     PISSN: 14352443     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00423-008-0445-9     Document Type: Review

References (79)

1. GS Martin DM Mannino S Eaton M Moss 2003 The epidemiology of sepsis in the United States from 1979 through 2000 N Engl J Med 348 1546 1554
2. JL Vincent Y Sakr CL Sprung VM Ranieri K Reinhart H Gerlach R Moreno J Carlet JR Le Gall D Payen 2006 Sepsis in European intensive care units: the SOAP study Crit Care Med 34 344 353
3. PS Barie MD Williams JS McCollam BM Bates RL Qualy SF Lowry DE Fry 2004 The PROWESS Surgical Evaluation Committee: benefit/risk profile of drotrecogin alfa (activated) in surgical patients with severe sepsis Am J Surg 188 212 220
4. H Wacha T Hau R Dittmer C Ohmann 1999 Risk factors associated with intraabdominal infections: a prospective multicenter study Langenbeck's Arch Surg 384 24 32
5. RG Sawyer DP Raymond SJ Pelletier 2001 Implications of 2,457 consecutive surgical infections entering year 2000 Ann Surg 233 867 874
6. C Farinas-Alvarez MC Farinas C Fernandez-Mazarrasa 2000 Analysis of risk factors for nosocomial sepsis in surgical patients Br J Surg 87 1076 1081
7. SE Wilson K Faulkner 1998 Impact of anatomical site on bacteriological and clinical outcome in the management of intra-abdominal infections Am Surg 64 402 407
8. Rüden H, Daschner F, Schumacher M (1995) Nosokomiale Infektionen in Deutschland- Erfassung und Prävention (NIDEP Studie), Teil 1. Prävalenz nosokomialer Infektionen, Qualitätssicherung in der Krankenhaushygiene, Bd 56. Schriftenreihe des Bundesministeriums für Gesundheit. Nomos, Baden-Baden
9. I Brook EH Frazier 1999 Microbiology of subphrenic abscesses: a 14-year experience Am Surg 65 1049 1053
10. F Bäckhed RE Ley JL Sonnenburg DA Peterson JI Gordon 2005 Host-bacterial mutualism in the human intestine Science 307 1915 1919
11. LV Hooper JL Gordon 2001 Commensal host-bacterial relationships in the gut Science 292 1115 1118
12. F Guarner JR Malagelada 2003 Gut flora in health and disease Lancet 361 512 519
13. J MacFie BS Reddy M Gatt PK Jain R Sowdi CJ Mitchell 2006 Bacterial translocation studied in 927 patients over 13 years Br J Surg 93 1 87 93
14. VB Nieuwenhuijs A Verheem H Duijvenbode-Beumer MR Visser J Verhoef HG Gooszen LM Akkermans 1998 The role of interdigestive small bowel motility in the regulation of gut microflora, bacterial overgrowth, and bacterial translocation in rats Ann Surg 228 188 93
15. EA Deitch X Dazhong MB Naruhn DC Deitch L Qi AA Marino 1995 Elemental diet and iv-TPN-induced bacterial translocation is associated with loss of intestinal mucosal barrier function against bacteria Ann Surg 221 299 307
16. S Bengmark 1999 Gut environment and immune function Curr Opin Clin Nutr Metab Care 2 83 85
17. D Seehofer N Rayes R Schiller 2004 Probiotics partly reverse increased bacterial translocation after simultaneous liver resection and colonic anastomosis in rats J Surg Res 117 262 271
18. P Naaber I Smidt K Tamme A Liigant H Tapfer M Mikelsaar R Talvik 2000 Translocation of indigenous microflora in an experimental model of sepsis J Med Microbiol 49 431 439
19. NSF Runkel FG Moody GS Smith LF Rodriguez MT LaRocco TA Miller 1991 The role of the gut in the development of sepsis in acute pancreatitis J Surg Res 51 18 23
20. DD Tran MA Cuesta PA van Leeuwen JJ Nauta RI Wesdorp 1993 Risk factors for multiple organ system failure and death in critically injured patients Surgery 114 21 30
21. WA Lane 1908 Results of the operative treatment of chronic constipation Br Med J 1 126
22. JG Mulder WE Wiersma GW Welling D van der Waaij 1984 Low dose oral tobramycin treatment for selective decontamination of the digestive tract: a study in human volunteers J Antimicrob Chemother 13 5 495 504
23. WC Hellinger JD Yao S Alvarez 2002 A randomized, prospective, double-blind evaluation of selective bowel decontamination Tranplantation 73 12 1904 1909
24. JH Zwaveling JK Maring IJ Klompmaker 2002 Selective decontamination of the digestive tract to prevent postoperative infection: a randomized placebo-controlled trial in liver transplant recipients Crit Care Med 30 6 1204 1209
25. GA O'May N Reynolds AR Smith A Kennedy GT Macfarlane 2005 Effect of pH and antibiotics on microbial overgrowth in the stomachs and duodena of patients undergoing percutaneous endoscopic gastrostomy feeding J Clin Microbiol 43 7 3059 3065
26. E Meyer F Schwab P Gastmeier H Rueden FD Daschner 2006 Surveillance of antimicrobial use and antimicrobial resistance in German intensive care units (SARI): a summary of the data from 2001 through 2004 Infection 34 6 303 309
27. DM Sievert JT Rudrik JB Patel LC McDonald MJ Wilkins JC Hageman 2008 Vancomycin-resistant Staphylococcus aureus in the United States, 2002-2006 Clin Infect Dis 46 5 668 674
28. DM Shlaes SJ Projan JE Edwards 2004 Antibiotic discovery: state of the state ASM News 70 275 281
29. J Schrezemeier M de Vrese 2001 Probiotics, prebiotics and synbiotics-approaching a definition Am J Clin Nutr 73 361 364
30. Mechnikov I (1908) The prolongation of human life, 1st ed. G.P. Putnams Sons, New York.
31. HC Lin BH Su AC Chen 2005 Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants. Outcome and cost of intensive care for very low birth weight infants Pediatrics 115 1 1 4
32. AL D'Souza C Raj Cumar J Cooke 2002 Probiotics in prevention of antibiotic associated diarrhoea: meta-analysis BMJ 324 7350 1361
33. J McCarthy L O'Mahony C Dunne 2001 An open trial of a novel probiotic as an alternative to steroids in mild/moderately active Crohn's disease Gut 49 Suppl 3 A2447
34. Q Liu ZP Duan K Ha da S Bengmark J Kurtovic SM Riordan 2004 Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis Hepatology 39 5 1441 1449
35. Z Li S Yang H Lin J Huang PA Watkins AB Moser C DeSimone XY Song AM Diehl 2003 Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease Hepatology 37 343 350
36. M Kalliomäki S Salminen H Arvilommi 2001 Probiotics in primary prevention of atopic disease: a randomised, placebo-controlled trial Lancet 357 1076 1079
37. G Reid D Charbonneau J Erb 2003 Oral use of Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 significantly alters vaginal flora: randomized, placebo controlled trial in 64 healthy women FEMS Immunol Med Microbiol 35 2 131 134
38. AL Servin 2004 Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens FEMS Microbial Rev 28 405 440
39. ML Marco S Pavan M Kleerezebem 2006 Towards understanding molecular modes of probiotic action Curr Opin Biotechnol 17 204 210
40. DR Mack S Michail S Wel 1999 Probiotics inhibit enteropathogenic E. coli adherence in vitro by inducing intestinal mucin gene expression Am J Physiol 276 G941 950
41. M Schlee J Harder B Köten EF Stange J Wehkamp A Fellermann 2008 Probiotic lactobacilli and VSL#3 induce enterocyte beta-defensin 2 Clin Exp Immunol 151 3 528 535
42. S Bengmark 2005 Bioecological control of the gastrointestinal tract: the role of flora and supplemented probiotics and synbiotics Gastroenterol Clin North Am 34 413 436
43. JM Otte DK Podolsky 2004 Functional modulation of enterocytes by gram-positive and gram-negative microorganisms Am J Physiol Gastrointest Liver Physiol 286 613 626
44. AL Hart K Lammers P Brigidi B Vitali F Rizzello P Gionchetti M Campieri SC Kamm MA Knight AJ Stagg 2004 Modulation of human dendritic cell phenotype and function by probiotic bacteria Gut 53 1602 1609
45. YH Sheih BL Chiang LH Wang CK Liao HS Gill 2001 Systemic immunity-enhancing effects in healthy subjects following dietary consumption of the lactic acid bacterium Lactobacillus rhamnosus HN001 J Am Coll Nutr 20 149 156
46. LE Niers HM Timmermann GT Rijkers GM van Bleek NO van Uden EF Knol 2005 Identification of strong interleukin-10 inducing lactic acid bacteria which down-regulate T helper type 2 cytokines Clin Exp Allergy 35 1481 1489
47. G Perdigon ME Nader de Macias S Alvarez 1988 Systemic augmentation of the immune response in mice by feeding fermented milks with Lactobacillus casei and Lactobacillus acidophilus Immunology 63 17 23
48. M Kaila E Isolauri E Soppi 1992 Enhancement of the circulating antibody secreting cell response in human diarrhoea by a human Lactobacillus strain Pediatr Res 32 141 144
49. S Salminen C Bouley MC Boutron-Ruault 1998 Functional food science and gastrointestinal physiology and function Br J Nutr 80 Suppl. 1 147 171
50. X Wang R Andersson V Soltesz W Guo S Bengmark 1993 Water-soluble ethylhydroxy Cellulose prevents bacterial translocation induced by major liver resection in the rat Ann Surg 217 155 167 (Pubitemid 23059287)
51. A Tsunoda M Shibusawa Y Tsunoda M Watanabe K Nomoto M Kusano 2002 Effect of Lactobacillus casei on a novel murine model of abdominal sepsis J Surg Res 107 1 37 43
52. D Seehofer N Rayes RA Schiller M Stockmann AR Müller A Schirmeier F Schaeper SG Tullius S Bengmark P Neuhaus 2004 Probiotics partly reverse increased bacterial translocation after simultaneous liver resection and colonic anastomosis in the rat J Surg Res 117 262 271
53. CE McNaught NP Woodcock J MacFie CJ Mitchell 2002 A prospective randomised study of the probiotic Lactobacillus plantarum 299v on indices of gut barrier function in elective surgical patients Gut 51 827 831
54. ADG Anderson CE McNaught PK Jain J MacFie 2004 Randomised clinical trial of synbiotic therapy in elective surgical patients Gut 53 241 245
55. BS Reddy J MacFie M Gatt CN Larsen SS Jensen TD Leser 2007 Randomized clinical trial of effect of synbiotics, neomycin and mechanical bowel preparation on intestinal barrier function in patients undergoing colectomy Br J Surg 94 546 554
56. N Rayes S Hansen D Seehofer 2002 Early enteral supply of fiber and lactobacilli versus conventional nutrition: a controlled trial in patients with major abdominal surgery Nutrition 18 609 615
57. PWT Pisters WA Hudec KR Hess JE Lee JN Vauthey S Lahoti I Raijman DB Evans 2001 Effect of preoperative biliary decompression on pancreaticoduodenectomy-associated morbidity in 300 consecutive cases Ann Surg 234 1 47 55
58. P Jagannath V Dhir S Shrikande RC Shah P Mullerpatan KM Mohandas 2005 Effect of preoperative biliary stenting on immediate outcome after pancreatoduodenectomy Br J Surg 92 356 361
59. T Nomura Y Tsuchiya A Nashimoto 2007 Probiotics reduce infectious complications after pancreaticoduodenectomy Hepato-Gastroenterology 54 661 663
60. N Rayes D Seehofer T Theruvath 2007 Effect of enteral nutrition and synbiotics on bacterial infection rates after pylorus-preserving pancreatoduodenectomy Ann Surg 246 36 41
61. A Olah T Belagyi A Issekutz ME Gamal S Bengmark 2002 Randomized clinical trial of specific Lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis Br J Surg 89 1103 1107
62. A Olah T Belagyi L Poto S Romics L Bengmark 2007 Synbiotic control of inflammation and infection in severe acute pancreatitis: a prospective, randomized, double-blind study Hepato-Gastroenterology 54 590 594
63. MGH Besselink HC van Santvoort E Buskens 2008 Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial Lancet 371 651 659
64. H Shigata M Nagino J Kamiya 2002 Bacteremia after hepatectomy: an analysis of a single-center, 10-year experience with 407 patients Langenbeck's Arch Surg 387 117 124
65. S Togo K Matsuo K Tanaka C Matsumoto T Shimizu M Ueda D Morioka Y Nagano I Endo H Shimada 2007 Perioperative infection control and its effectiveness in hepatectomy patients J Gastroenterol Hepatol 22 11 1942 1948
66. X Wang R Andersson V Soltesz L Wang S Bengmark 1993 Effect of portal hypertension on bacterial translocation induced by major liver resection in rats Eur J Surg 159 343 350 (Pubitemid 23205770)
67. X Wang WD Guo Q Wang R Andersson E Ekblad V Soltesz S Bengmark 1994 The association between enteric bacterial overgrowth and gastrointestinal motility after subtotal resection or portal vein obstruction in rats Eur J Surg 160 153 160
68. S Zeuzem 2000 Gut-liver axis Int J Colorectal Dis 15 2 59 82
69. H Kanazawa M Nagino S Kamiya 2005 Synbiotics reduce postoperative infectious complications: a randomized controlled trial in biliary cancer patients undergoing hepatectomy Langenbecks Arch Surg 390 104 113
70. G Sugawara M Nagino H Nishio 2006 Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery. A randomized controlled trial Ann Surg 244 706 714
71. N Rolando J Philpott-Howard R Williams 1996 Bacterial and fungal infection in acute liver failure Semin Liver Dis 16 389 402 (Pubitemid 27074781)
72. N Rayes WO Bechstein H Keck G Blumhardt R Lohmann P Neuhaus 1995 Todesursachen nach Lebertransplantation: eine Analyse von 41 Fällen bei 382 Patienten Zentralbl Chir 120 435 438
73. CS Hollenbaek EJ Alfrey WW Souba 2001 The effect of surgical site infection on outcomes and resource utilization after liver transplantation Surgery 130 388 395
74. N Rayes D Seehofer S Hansen K Boucsein AR Müller S Serke S Bengmark P Neuhaus 2002 Early enteral supply of Lactobacillus and fiber versus selective bowel decontamination: a controlled trial in liver transplant recipients Transplantation 74 1 123 128
75. N Rayes D Seehofer T Theruvath RA Schiller JM Langrehr S Jonas S Bengmark P Neuhaus 2005 Supply of pre- and probiotics reduces bacterial infection rates after liver transplantation-a randomized, double-blind trial Am J Transplant 5 125 130
76. JM Hammond PD Potgieter GL Saunders 1994 Selective decontamination of the digestive tract in multiple trauma patients-is there a role? Results of a prospective, double-blind, randomized trial Crit Care Med 22 1 33 39
77. K Kotzampassi EJ Giamarellos-Bourboulis A Voudouris P Kazamias E Eleftheriadis 2006 Benefits of a synbiotic formula (Synbiotic 2000forte) in critically ill trauma patients: early results of a randomized controlled trial World J Surg 30 1848 1855
78. A Spindler-Vesel S Bengmark I Vovk O Cerovic L Kompan 2007 Synbiotics, prebiotics, glutamine, or peptide in early enteral nutrition: a randomized study in trauma patients J Parent Enteral Nutr 31 119 126
79. E Isolauri S Salminen 2005 Probiotics, gut inflammation and barrier function Gastroenterol Clin N Am 34 437 450