Transcriptomic profile of two canine mammary cancer cell lines with different proliferative and anti-apoptotic potential

Journal of Physiology and Pharmacology

Volumn 60, Issue SUPPL. 1, 2009, Pages 95-106

  Krol, M ^a   Pawlowski, K M ^a   Skierski, J ^b   Rao, N A S ^c   Hellmen, E ^d   Mol, J A ^c   Motyl, T ^a  

^a WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

^b National Medicines Institute   (Poland)

^c UTRECHT UNIVERSITY   (Netherlands)

^d SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Canine mammary cancer; cDNA microarray; Cell line gene expression; Gene expression profile

Indexed keywords

BETA1 INTEGRIN; CALMODULIN; CALMODULIN 1; CALMODULIN 2; CALMODULIN 3; CELL NUCLEUS RECEPTOR; CELL PROTEIN; DEOXYRIBONUCLEASE II; DEOXYRIBONUCLEASE II BETA; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E BINDING PROTIEIN 3; GROWTH FACTOR; GROWTH HORMONE RECEPTOR; INITIATION FACTOR; MEMBRANE PROTEIN; NEU DIFFERENTIATION FACTOR; NUCLEIC ACID BINDING PROTEIN; PROTEIN ARHGAP26; PROTEIN BCL 2; PROTEIN DDEFL1; PROTEIN LIN7A; PROTEIN NR6A1; PROTEIN RPS6KA2; PROTEIN TMEFF1; PROTEIN ZFAND6; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RIBOSOME PROTEIN; SMAD1 PROTEIN; TETRASPANIN; TETRASPANIN 6; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; APOPTOSIS; BREAST CANCER; CANCER CELL CULTURE; CELL ADHESION; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; SIGNAL TRANSDUCTION; SPINDLE CELL CARCINOMA; TRANSCRIPTOMICS;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DOGS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; MAMMARY NEOPLASMS, ANIMAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 67749101213     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (48)

1. Dorn CR, Taylor DON, Frye FL, Hibbard HH. Survey of animal neoplasms in Alemeda and Contra Costa Counties, California I. Methodology and description of cases. J Natl Cancer Inst 1968; 40: 295-305.
2. El Etreby MF, Muller-Peddinghaus R, Bhargava AC, Fath El bar MR, Graf KJ, Trautwein G. The role of the pituitary gland in spontaneous canine mammary carcinogenesis. Vet Pathol 1980; 17: 2-16.
3. McVean DW, Monlux AW, Anderson PS, Silverberg SL, Roszel JF. Frequency of canine and feline tumors in a defined population. Vet Pathol 1978; 15: 700-715.
4. Rijnberk A, Kooistra HS, Mol JA. Endocrine diseases in dogs and cats: similarities and differences with endocrine diseases in humans. Growth Hormon IGF Res 2003; 13: 158-164. (Pubitemid 37161676)
5. Beckmann MW, Niederacher D, Schnurch HG, Gusterson BA, Bender HG. Multistep carcinogenesis of breast cancer and tumor heterogeneity. J Mol Med 1997; 75: 429-439. (Pubitemid 27297013)
6. Ingvarsson S. Molecular genetics of breast cancer progression. Semin Cancer Biol 1999; 9: 277-288. (Pubitemid 29429992)
7. nd series, vol.7, pp 1-59.
8. Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001; 98: 10869-10874. (Pubitemid 32878711)
9. Hellmen E. Characterization of four in vitro established canine mammary carcinoma and one atypical benign mixed tumor cell lines. In Vitro Cell Dev Biol 1992; 5: 309-319.
10. Hellmen E, Moller M, Blankenstein MA, Andersson L, Westermark B. Expression of different phenotypes in cell lines from canine mammary spindle-cell tumours and osteosarcomas indicating a pluripotent mammary stem cell origin. Breast Cancer Res Treat 2000; 61: 197-210. (Pubitemid 30609553)
11. Darzynkiewicz Z, Robinson JP, Crissman HA. Methods In Cell Biology. Flow Cytometry 1994; 41: Part A.
12. Rao NAS, Wolferen van ME, Ham van den R et al. cDNA mocroarray profiles of canine mammary tumor cell lines reveal deregulated pathways pertaining to their phenotype. Animal Genetics 2008; 39: 333-345.
13. Oshlack A, Emsile D, Corcoran LM, Smyth GK. Normalization of boutique two-color microarrays with a high proportion of differentially expressed probes. Genome Biol 2007; 8: R2. (Pubitemid 351910999)
14. Park DS, Morris EJ, Greene LA, Geller HM. G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis. J Neurosci 1997; 17: 1256-1270.
15. Bhonde MR, Hanski ML, Notter M et al. Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth. Oncogene 2006; 25: 165-175. (Pubitemid 43083678)
16. Rodriguez-Mora OG, LaHair MM, McCubrey JA, Franklin RA. Calcium/calmodulin-dependent kinase I and calcium/calmodulin-dependent kinase kinase participate in the control of cell cycle progression in MCF-7 human breast cancer cells. Cancer Res, 2005; 65: 5408-5416. (Pubitemid 40827354)
17. Biswas KB, Reddy PV, Pickard M, Makkad B, Pettit N, Pardee AB. Calmodulin is essential for estrogen receptor interaction with its motif and activation of responsive promoter. J Biol Chem 1998; 273: 33817-33824. (Pubitemid 29005774)
18. Mol JA, Garderen van E, Selman PJ, Wolfswinkel J, Rijnberk A, Rutteman GE. Growth hormone mRNA in mammary gland tumors in dogs and cats. J Clin Invest 1995; 95: 2028-2034.
19. Gil-Puig C, Blanco M, Garcia-Caballero T, Segura C, Perez-Fernardez R. Pit-1/GHF-1 and GH expression in the MCF-7 human breast adenocarcinoma cell line. J Endocrinol 2002; 173: 161-167. (Pubitemid 34428902)
20. Zhu T, Starling-Emerald B, Zhang X et al. Oncogenic transformation of human mammary epithelial cells by autocrine human growth hormone. Cancer Res 2005; 65: 317-324. (Pubitemid 40070824)
21. Mukhina S, Mertani HC, Guo K, Lee KO, Gluckman PD, Lobie PE. Phenotypic conversion of human mammary carcinoma cells by autocrine human growth hormone. Proc Natl Acad Sci USA 2004; 101: 15166-15171. (Pubitemid 39391736)
22. Yue J, Mulder KM. Transforming growth factor-beta signal transduction in epithelial cells. Pharmacol Ther 2001; 91: 1-34. (Pubitemid 33055772)
23. Massague J. TGF-beta signal transduction. Annu Rev Biochem 1998; 67: 753-791.
24. Derynck R, Akhurst RJ, Balmain A. TGF-beta signaling in tumor suppression and cancer progression. Nat Genet 2001; 29: 117-129. (Pubitemid 32952643)
25. Kolek O, Gajkowska B, Godlewski MM, Motyl T. Molecular mechanism of TGF-β1-induced apoptosis in HC11 mouse mammary epithelial cells (MEC). Cell Mol Biol 2001; 47: 197-208.
26. Kolek O, Gajkowska B, Godlewski MM, Motyl T. Colocalization of apoptosis-regulating proteins in mouse mammary epithelial HC11 cells exposed to TGF-β1. Eur J Cell Biol 2003; 82: 303-312. (Pubitemid 36818154)
27. Kolek O, Gajkowska B, Godlewski MM, Motyl T. Antiproliferative and apoptotic effect of TGF-β1 in bovine mammary epithelial BME-UV1 cells. Comp Biochem Physiol C 2003; 134: 417-430. (Pubitemid 36514991)
28. Gajewska M, Motyl T. IGF binding protein mediate TGF-β1-induced apoptosis in bovine mammary epithelial BME-UV1 cells. Comp Biochem Physiol C 2004; 139: 65-75. (Pubitemid 39535789)
29. Gajewska M, Gajkowska B, Motyl T. Apoptosis and autophagy induced by TGF-β1 in bovine mammary epithelial BME-UV1 cells. J Physiol Pharmacol 2005; 56: 143-157. (Pubitemid 43129239)
30. 1 and suppression of somatotropic pathway. Polish J Vet Sci 2007; 10: 1-9.
31. Jhappan C, Geiser AG, Kordon EC et al. Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation. EMBO J 1993; 12 : 1835-1845. (Pubitemid 23157699)
32. Pierce DF, Gorska AE, Chytil A et al. Mammary tumor suppression by transforming growth factor beta 1 transgene expression. Proc Natl Acad Sci USA 1995; 92: 4254-4258.
33. Dumont N, Arteaga CL. Transforming growth factor-beta and breast cancer: tumor promoting effects of transforming growth factor-beta. Breast Cancer Res. 2000; 2: 125-132. (Pubitemid 32223575)
34. Muraoka RS, Dumont N, Ritter CA et al. Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest 2002; 109: 1551-1559. (Pubitemid 34663517)
35. Esparis-Ogando A, Diaz-Rodriguez E, Montero JC, Yuste L, Crespo P, Pandiella A. Erk5 Participates in Neuregulin Signal Transduction and Is Constitutively Active in Breast Cancer Cells Overexpressing ErbB2. Mol Cell Biol 2002; 22: 270-285. (Pubitemid 33144274)
36. Riese DJ, Raaij van TM, Plowman GD, Andrews GC, Stern DF. The cellular response to neuregulins is governed by complex interactions of the ErbB receptor family. Mol Cell Biol, 1995; 10: 5770-5776.
37. Giancotti FG, Ruoslahti E. Integrin signaling. Science 1999; 285: 1028-1032.
38. White DE, Kurpios NA, Zuo D et al. Targeted disruption of h1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell 2004; 6: 159-170. (Pubitemid 39485688)
39. Shaw LM. Integrin function in breast carcinoma progression. J Mammary Gland Biol Neoplasia 1999; 4: 367-376.
40. Zutter MM, Krigman HR, Santoro SA. Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization. Am J Pathol 1993; 142: 1439-1448. (Pubitemid 24058131)
41. Aoudjit F, Vuori K. Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene 2001; 20: 4995-5004. (Pubitemid 32769789)
42. Lewis JM, Truong TN, Schwartz MA. Integrins regulate the apoptotic response to DNA damage through modulation of p53. Proc Natl Acad Sci USA 2002; 99: 3627-3632.
43. Sethi T, Rintoul RC, Moore SM et al. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med 1999; 5: 662-668. (Pubitemid 29289430)
44. Kawamura T, Endo Y, Yonemura Y et al. Significance of integrin a2/h1 in peritoneal dissemination of a human gastric cancer xenograft model. Int J Oncol 2001; 18: 809-815.
45. Fujita S, Watanabe M, Kubota T et al. Alteration of expression in integrin h1-subunit correlates with invasion and metastasis in colorectal cancer. Cancer Lett 1995; 91: 145-149.
46. Elliott BE, Ekblom P, Pross H et al. Anti-h1 integrin IgG inhibits pulmonary macrometastasis and the size of micrometastases from a murine mammary carcinoma.Cell Adhes Commun 1994; 1: 319-332. (Pubitemid 24082199)
47. Park CC, Zhang H, Pallavicini M et al. B1 Integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res 2006; 66: 1525-1535. (Pubitemid 43259934)
48. Berditchevski F, Odintsova E. Characterization of integrin-tetraspanin adhesion complexes: role of tetraspanins in integrin signaling. J Cell Biol 1999; 146: 477-492. (Pubitemid 29369782)