Immunohistochemical localization of insulin-like growth factor binding protein 2 in the central nervous system of SOD1G93A transgenic mice

Journal of Molecular Histology

Volumn 40, Issue 2, 2009, Pages 157-163

  Sim, Sung Eun ^a   Chung, Yoon Hee ^b   Jeong, Ji Hoon ^b   Yun, Sin Weon ^b   Lim, Hyoun Sub ^c   Kim, Daejin ^b   Kim, Sung Su ^b   Lee, Won Bok ^b   Cha, Choong Ik ^a  

^a Seoul National University   (South Korea)

^b Chung Ang University   (South Korea)

^c AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Amyotrophic lateral sclerosis (ALS); Cerebral cortex; Hippocampus; Immunohistochemistry; Insulin like growth factor binding protein 2 (IGFBP2); SOD1G93A transgenic mice

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 2;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY CORTEX; BRAIN CORTEX; BRAIN REGION; BRAIN STEM; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DENTATE GYRUS; EXPERIMENTAL MODEL; EXPERIMENTAL MOUSE; FACIAL NERVE NUCLEUS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; MOUSE; MUTANT; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PYRIFORM CORTEX; RAPHE NUCLEUS; SOD1 MUTANT; SOMATOSENSORY CORTEX; SPINAL CORD; TRANSGENIC MOUSE; TRIGEMINAL NUCLEUS; VESTIBULAR NERVE; VISUAL CORTEX; WILD TYPE;

ANIMALS; BRAIN; BRAIN STEM; CENTRAL NERVOUS SYSTEM; CEREBRAL CORTEX; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; MICE; MICE, TRANSGENIC; SPINAL CORD;

MUS MUSCULUS;

EID: 67651236470     PISSN: 15672379     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10735-009-9219-0     Document Type: Article

References (22)

1. D Chesik J De Keyser N Wilczak 2007 Insulin-like growth factor binding protein-2 as a regulator of IGF actions in CNS: implications in multiple sclerosis Cytokine Growth Factor Rev 18 267 278 10.1016/j.cytogfr.2007.04.001 (Pubitemid 46891286)
2. JA Chowen L Goya S Ramos S Busiguina LM Garcia-Segura J Argente AM Pascual-Leone 2002 Effects of early undernutrition on the brain insulin-like growth factor-I system J Neuroendocrinol 14 163 169 10.1046/j.0007-1331.2001. 00758.x (Pubitemid 34071965)
3. G93A mutant transgenic mice Brain Res 994 253 259 10.1016/j.brainres.2003.09.047 (Pubitemid 37464889)
4. DR Clemmons 1997 Insulin-like growth factor binding proteins and their role in controlling IGF actions Cytokine Growth Factor Rev 8 45 62 10.1016/S1359-6101(96)00053-6 (Pubitemid 27214688)
5. DW Cleveland JD Rothstein 2001 From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS Nat Rev Neurosci 2 806 819 10.1038/35097565 (Pubitemid 33674062)
6. PF Collett-Solberg P Cohen 1996 The role of the insulin-like growth factor binding proteins and the IGFBP proteases in modulating IGF action Endocrinol Metab Clin North Am 25 591 614 10.1016/S0889-8529(05)70342-X
7. AJ D'Ercole P Ye AS Calikoglu G Gutierrez-Ospina 1996 The role of the insulin-like growth factors in the central nervous system Mol Neurobiol 13 227 255 10.1007/BF02740625
8. S Dore C Krieger S Kar R Quirion 1996 Distribution and levels of insulin-like growth factor (IGF-I and IGF-II) and insulin receptor binding sites in the spinal cords of amyotrophic lateral sclerosis (ALS) patients Brain Res Mol Brain Res 41 128 133 10.1016/0169-328X(96)00081-2 (Pubitemid 26288152)
9. E Ekestern 2004 Neurotrophic factors and amyotrophic lateral sclerosis Neurodegener Dis 1 88 100 10.1159/000080049 (Pubitemid 39369422)
10. EF Goodall KE Morrison 2006 Amyotrophic lateral sclerosis (motor neuron disease): proposed mechanisms and pathways to treatment Expert Rev Mol Med 8 1 22 10.1017/S1462399406010854
11. ME Gurney H Pu AY Chiu 1994 Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation Science 264 1772 1775 10.1126/science.8209258 (Pubitemid 24227760)
12. JI Jones DR Clemmons 1995 Insulin-like growth factors and their binding proteins: biological actions Endocr Rev 16 3 34
13. G93A transgenic mice as an in vivo model of amyotrophic lateral sclerosis Ann Anat 190 502 509 10.1016/j.aanat.2008.08.001
14. BK Kaspar J Llado N Sherkat JD Rothstein FH Gage 2003 Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model Science 301 839 842 10.1126/science.1086137 (Pubitemid 36962626)
15. H Kerkhoff SM Hassan D Troost RW Van Etten H Veldman FG Jennekens 1994 Insulin-like and fibroblast growth factors in spinal cords, nerve roots and skeletal muscle of human controls and patients with amyotrophic lateral sclerosis Acta Neuropathol 87 411 421 10.1007/BF00313611
16. A Logan AM Gonzalez DJ Hill M Berry NA Gregson A Baird 1994 Coordinated pattern of expression and localization of insulin-like growth factor-II (IGF-II) and IGF-binding protein-2 in the adult rat brain Endocrinology 135 2255 2264 10.1210/en.135.5.2255 (Pubitemid 24363926)
17. T Pirttilä S Vanhatalo U Turpeinen R Riikonen 2004 Cerebrospinal fluid insulin-like growth factor-1, insulin growth factor binding protein-2 or nitric oxide are not increased in MS or ALS Acta Neurol Scand 109 337 341 10.1111/j.1600-0404.2004.00223.x (Pubitemid 38580901)
18. LP Rowland NA Shneider 2001 Amyotrophic lateral sclerosis N Engl J Med 344 1688 1700 10.1056/NEJM200105313442207 (Pubitemid 32479968)
19. I Torres-Aleman V Barrios J Berciano 1998 The peripheral insulin-like growth factor system in amyotrophic lateral sclerosis and in multiple sclerosis Neurology 50 772 776
20. JM Wang T Hayashi WR Zhang K Sakai Y Shiro K Abe 2000 Reduction of ischemic brain injury by topical application of insulin-like growth factor-I after transient middle cerebral artery occlusion in rats Brain Res 859 381 385 10.1016/S0006-8993(00)02008-4 (Pubitemid 30136115)
21. N Wilczak J De Keyser 2005 Insulin-like growth factor system in amyotrophic lateral sclerosis Endocr Dev 9 160 169 10.1159/000085764
22. N Wilczak RA de Vos J De Keyser 2003 Free insulin-like growth factor (IGF)-I and IGF binding proteins 2, 5, and 6 in spinal motor neurons in amyotrophic lateral sclerosis Lancet 361 1007 1011 10.1016/S0140-6736(03)12828-0 (Pubitemid 36355935)