P63 Immunoexpression in lip carcinogenesis

Journal of Molecular Histology

Volumn 40, Issue 2, 2009, Pages 131-137

  Xavier, Flávia Caló Aquino ^a,c   Takiya, Christina Maeda ^b   Reis, Sílvia Regina Almeida ^a   Ramalho, Luciana Maria Pedreira ^a  

^a FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c Praia do Castelo   (Brazil)

Author keywords

Actinic cheilitis; Immunohistochemistry; Lip neoplasms; Squamous cell carcinoma; Tumor biological markers

Indexed keywords

PROTEIN P53; PROTEIN P63; TUMOR MARKER;

ACTINIC CHEILITIS; ARTICLE; CANCER GRADING; CARCINOGENESIS; CHEILITIS; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; EPITHELIUM DYSPLASIA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIP CARCINOMA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SQUAMOUS CELL CARCINOMA;

EID: 67651227152     PISSN: 15672379     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10735-009-9223-4     Document Type: Article

References (36)

1. G Anneroth J Batsakis M Luna 1987 Review of the literature and a recommended system of malignancy grading in oral squamous cell carcinomas Scand J Dent Res 95 229 249
2. J Banoczy A Csiba 1976 Occurrence of epithelial dysplasia in oral leukoplakia. Analysis and follow-up study of 12 cases Oral Surg Oral Med Oral Pathol 42 766 774 10.1016/0030-4220(76)90099-2
3. CA Beltrami L Desinan C Rubini 1992 Prognostic factors in squamous cell carcinoma of the oral cavity. A retrospective study of 80 cases Pathol Res Pract 188 510 516
4. MC Bortoluzzi LS Yurgel NP Dekker RC Jordan JA Regezi 2004 Assessment of p63 expression in oral squamous cell carcinoma and dysplasias Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98 698 704 10.1016/j.tripleo.2004.04.001 (Pubitemid 39610457)
5. M Bryne HS Koppang R Lilleng T Stene G Bang E Dabelsteen 1989 New malignance grading is a better prognostic indicator than Broders' grading in oral squamous cell carcinomas J Oral Pathol Med 18 432 437 10.1111/j.1600-0714. 1989.tb01339.x
6. E Cataldo HC Doku 1981 Solar cheilitis J Dermatol Surg Oncol 7 989 995
7. ASR Cavalcante AL Anbinder YR Carvalho 2008 Actinic cheilitis: clinical and histological features J Oral Maxillofac Surg 66 498 503 10.1016/j.joms.2006. 09.016 (Pubitemid 351226348)
8. YK Chen SS Hsue LM Lin 2004 Expression of p63 (TA and ΔN isoforms) in human primary well differentiated buccal carcinomas Int J Oral Maxillofac Surg 33 493 497 10.1016/j.ijom.2003.10.023 (Pubitemid 38950217)
9. YK Chen SS Hsue LM Lin 2005 Expression of p63 protein and mRNA in oral epithelial dysplasia J Oral Pathol Med 34 232 239 10.1111/j.1600-0714.2004. 00277.x (Pubitemid 40445157)
10. HR Choi JG Batsakis F Zhan E Sturgis MA Luna AK El-Naggar 2002 Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis Hum Pathol 33 158 164 10.1053/hupa.2002.30722 (Pubitemid 34298729)
11. V de Laurenzi A Rossi A Terrinoni D Barcaroli M Levrero A Costanzo RA Knight P Guerrieri G Melino 2000 p63 and p73 transactivate differentiation gene promoters in human keratinocytes Biochem Biophys Res Commun 273 342 346 10.1006/bbrc.2000.2932 (Pubitemid 30426908)
12. I de Rosa S Staibano L Lo Muzio M Delfino A Lucariello A Coppola G de Rosa C Scully 1999 Potentially malignant and malignant lesions of the lip. Role of silver staining nucleolar organizer regions, proliferation cell nuclear antigen, p53, and c-myc in differentiation and prognosis J Oral Pathol Med 28 252 258
13. G Fabbrocini N Russo MC Pagliuca 2000 p53, cyclin-D1, PCNA, AgNOR expression in squamous cell cancer of the lip: a multicenter study Photodermatol Photoimmunol Photomed 16 172 177 10.1034/j.1600-0781.2000.160405.x (Pubitemid 30666080)
14. MP Foschini A Gaiba R Cocchi MG Pennesi MR Gatto GP Frezza A Pession 2004 Pattern of p63 expression in squamous cell carcinoma of the oral cavity Virchows Arch 444 332 339 10.1007/s00428-003-0969-x (Pubitemid 38553637)
15. SC Girod P Pfeiffer J Ries HD Pape 1998 Proliferative activity and loss of function of tumor suppressor genes as 'biomarkers' in diagnosis and prognosis of benign and preneoplastic oral lesions and oral squamous cell carcinoma Br J Oral Maxillofac Surg 36 252 260 10.1016/S0266-4356(98)90708-2 (Pubitemid 28410074)
16. GE Kaugars T Pillion JA Svirsky DG Page JC Burns LM Abbey 1999 Actinic cheilitis: a review of 152 cases Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88 181 186 10.1016/S1079-2104(99)70115-0
17. KM Liefer MI Koster XJ Wang A Yang F McKeon D Roop 2000 Down-regulation of p63 is required for epidermal UV-B-induced apoptosis Cancer Res 60 4016 4020
18. L Lo Muzio A Santarelli R Caltabiano C Rubini T Pieramici L Trevisiol F Carinci R Leonardi A De Lillo S Lanzafame P Bufo A Piattelli 2005 p63 overexpression associates with poor prognosis in head and neck squamous cell carcinoma Hum Pathol 36 187 194 10.1016/j.humpath.2004.12.003 (Pubitemid 40313576)
19. A Markopoulos E Albanidou-Farmaki I Kayavis 2004 Actinic cheilitis: clinical and pathologic characteristics in 65 cases Oral Dis 10 212 216 10.1111/j.1601-0825.2004.01004.x (Pubitemid 38868573)
20. A Martínez U Brethauer J Borlando ML Spencer IG Rojas 2008 Epithelial expression of p53, mdm-2 and p21 in normal lip and actinic cheilitis Oral Oncol 4 878 883 10.1016/j.oraloncology.2007.11.008
21. SG Nicolau L Baelus 1964 Chronic actinic cheilitis and cancer of the lower lip Br J Dermatol 76 278 289 10.1111/j.1365-2133.1964.tb14529.x
22. K Nylander PJ Coates PA Hall 2000 Characterization of expression pattern of p63α and ΔNp63α in benign and malignant oral epithelial lesions Int J Cancer 87 368 372 10.1002/1097-0215(20000801)87:3<368::AID- IJC9>3.0.CO;2-J (Pubitemid 30451647)
23. R Parsa A Yang F McKeon H Green 1999 Association of p63 with proliferative potential in normal and neoplastic human keratinocytes J Invest Dermatol 113 1099 1105 10.1046/j.1523-1747.1999.00780.x (Pubitemid 30013359)
24. DD Picascia JK Robinson 1987 Actinics cheiliti: a review of the etiology, differential diagnosis and treatment J Am Acad Dermatol 17 255 264 10.1016/S0190-9622(87)70201-1
25. Pindborg JJ, Reichart PA, Smith CJ, van der Waal I (1997) Histological typing of cancer and precancer of the oral mucosa. WHO international classification of tumours. Springer, Berlin
26. JS Reis-Filho FC Schmitt 2002 Taking advantage of basic research: p63 is a reliable myoepithelial and stem cell marker Adv Anat Pathol 9 280 289 10.1097/00125480-200209000-00002
27. JS Reis-Filho B Torio A Albergaria FC Schmitt 2002 p63 expression in normal skin and usual cutaneous carcinomas J Cutan Pathol 29 517 523 10.1034/j.1600-0560.2002.290902.x (Pubitemid 35193295)
28. CM Rubira NJ Devides LT Ubeda AG Bortolucci Jr JR Lauris IR Rubira-Bullen JH Damante 2007 Evaluation of some oral postradiotherapy sequelae in patients treated for head and neck tumors Braz Oral Res 21 272 277 10.1590/S1806- 83242007000300014
29. JN Santos SOM Sousa FD Nunes MN Sotto VC Araújo 2003 Altered cytokeratin expression in actinic cheilitis J Cutan Pathol 30 237 241 10.1046/j.0303-6987.2002.028.x (Pubitemid 36555130)
30. M Senoo F Pinto CP Crum F McKeon 2007 p63 is essential for the proliferative potential of stem cells in stratified epithelia Cell 129 523 536 10.1016/j.cell.2007.02.045 (Pubitemid 46660965)
31. N Thurfjell PJ Coates T Uusitalo D Mahani E Dabelsteen A Dahlqvist B Sjöström G Roos K Nylander 2004 Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of head and neck Int J Oncol 25 27 35
32. I van der Waal 2009 Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management Oral Oncol 45 317 323 10.1016/j.oraloncology.2008.05.016
33. DA Wrone S Yoo LK Chipps RL Moy 2004 The expression of p63 in actinic keratoses, seborrheic keratosis, and cutaneous squamous cell carcinomas Dermatol Surg 30 1299 1302 10.1111/j.1524-4725.2004.30403.x (Pubitemid 39422956)
34. K Yamaguchi L Wu OL Caballero K Hibi B Trink V Resto P Cairns K Okami WM Koch D Sidransky J Jen 2000 Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma Int J Cancer 86 684 689 10.1002/(SICI)1097-0215(20000601)86:5<684::AID-IJC13>3.0.CO;2-M (Pubitemid 30249880)
35. A Yang F Mckeon 2000 p63 and p73: p53 mimics, menaces and more Nat Rev Mol Cell Biol 1 199 207 10.1038/35043127
36. A Yang M Kaghad Y Wang E Gillett MD Fleming V Dötsch NC Andrews D Caput F McKeon 1998 p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities Mol Cell 2 305 316 10.1016/S1097-2765(00)80275-0