Establishment of an adult mouse model for direct evaluation of the efficacy of vaccines against Vibrio cholerae

Infection and Immunity

Volumn 77, Issue 8, 2009, Pages 3475-3484

  Nygren, E ^a   Li, B L ^a   Holmgren, J ^a   Attridge, S R ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; CHOLERA VACCINE; LIPOPOLYSACCHARIDE; STREPTOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM PILUS; CECUM; CHOLERA; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; INOCULATION; LARGE INTESTINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIBRIO CHOLERAE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES, BACTERIAL; CECUM; CHOLERA; CHOLERA VACCINES; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, BACTERIAL; FECES; FEMALE; INTESTINE, LARGE; MICE; MICE, INBRED BALB C; MUCOUS MEMBRANE; STREPTOMYCIN; VIBRIO CHOLERAE O1; VIBRIO CHOLERAE O139;

EID: 67651205635     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01197-08     Document Type: Article

References (33)

1. Albert, M. J., K. Alam, M. Ansaruzzaman, F. Qadri, and R. B. Sack. 1994. Lack of cross-protection against diarrhea due to Vibrio cholerae O139 (Bengal strain) after oral immunization of rabbits with V. cholerae O1 vaccine strain CVD103-HgR. J. Infect. Dis. 169:230-231.
2. Albert, M. J., A. K. Siddique, M. S. Islam, A. S. Faruque, M. Ansaruzzaman, S. M. Faruque, and R. B. Sack. 1993. Large outbreak of clinical cholera due to Vibrio cholerae non-O1 in Bangladesh. Lancet 341:704.
3. Anh, D. D., G. Canh do, A. L. Lopez, V. D. Thiem, P. T. Long, N. H. Son, J. Deen, L. von Seidlein, R. Carbis, S. H. Han, S. H. Shin, S. Attridge, J. Holmgren, and J. Clemens. 2007. Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults. Vaccine 25:1149-1155.
4. Anonymous. 2006. Cholera 2005. Wkly. Epidemiol. Rec. 81:297-307.
5. Attridge, S. R., A. Fazeli, P. A. Manning, and U. H. Stroeher. 2001. Isolation and characterization of bacteriophage-resistant mutants of Vibrio cholerae O139. Microb. Pathog. 30:237-246.
6. Attridge, S. R., P. A. Manning, J. Holmgren, and G. Jonson. 1996. Relative significance of mannose-sensitive hemagglutinin and toxin-coregulated pili in colonization of infant mice by Vibrio cholerae El Tor. Infect. Immun. 64:3369-3373.
7. Butterton, J. R., E. T. Ryan, R. A. Shahin, and S. B. Calderwood. 1996. Development of a germfree mouse model of Vibrio cholerae infection. Infect. Immun. 64:4373-4377.
8. Flach, C. F., F. Qadri, T. R. Bhuiyan, N. H. Alam, E. Jennische, I. Lonnroth, and J. Holmgren. 2007. Broad up-regulation of innate defense factors during acute cholera. Infect. Immun. 75:2343-2350.
9. Herrington, D. A., R. H. Hall, G. Losonsky, J. J. Mekalanos, R. K. Taylor, and M. M. Levine. 1988. Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans. J. Exp. Med. 168:1487-1492.
10. Holmgren, J., and C. Bergquist. 2004. Oral B subunit-killed whole cell cholera vaccine, p. 499-509. In M. Levine, J. Kaper, R. Rappuoli, M. Liu, and M. Good (ed.), New generation vaccines, 3rd ed. Marcel Dekker, New York, NY.
11. Holmgren, J., A. M. Svennerholm, I. Lonnroth, M. Fall-Persson, B. Markman, and H. Lundbeck. 1977. Development of improved cholera vaccine based on subunit toxoid. Nature 269:602-604.
12. International Centre for Diarrhoeal Diseases Research. 1993. Large epidemic of cholera-like disease in Bangladesh caused by Vibrio cholerae O139 synonym Bengal. Lancet 342:387-390.
13. Jertborn, M., A. M. Svennerholm, and J. Holmgren. 1996. Intestinal and systemic immune responses in humans after oral immunization with a bivalent B subunit-O1/O139 whole cell cholera vaccine. Vaccine 14:1459-1465.
14. Knop, J., and D. Rowley. 1975. Antibacterial mechanisms in the intestine: elimination of Vibrio cholerae from the gastrointestinal tract of adult mice. Aust. J Exp. Biol. Med. Sci. 53:137-146.
15. Lange, S., and J. Holmgren. 1978. Protective antitoxic cholera immunity in mice: influence of route and number of immunizations and mode of action of protective antibodies. Acta Pathol. Microbiol. Scand. 86C:145-152.
16. Levine, M. M., J. B. Kaper, D. Herrington, G. Losonsky, J. G. Morris, M. L. Clements, R. E. Black, B. Tall, and R. Hall. 1988. Volunteer studies of deletion mutants of Vibrio cholerae O1 prepared by recombinant techniques. Infect. Immun. 56:161-167.
17. Levine, M. M., and C. O. Tacket. 1994. Recombinant live cholera vaccines, p. 395-413. In I. K. Wachsmuth, P. A. Blake, and O. Olsvik (ed.), Vibrio cholerae and cholera: molecular to global perspectives. ASM Press, Washington, DC.
18. Merrell, D. S., and A. Camilli. 1999. The cadA gene of Vibrio cholerae is induced during infection and plays a role in acid tolerance. Mol. Microbiol. 34:836-849.
19. Nair, G. B., T. Ramamurthy, S. K. Bhattacharya, A. K. Mukhopadhyay, S. Garg, M. K. Bhattacharya, T. Takeda, T. Shimada, Y. Takeda, and B. C. Deb. 1994. Spread of Vibrio cholerae O139 Bengal in India. J. Infect. Dis. 169:1029-1034.
20. Nandy, R. K., M. J. Albert, and A. C. Ghose. 1996. Serum antibacterial and antitoxin responses in clinical cholera caused by Vibrio cholerae O139 Bengal and evaluation of their importance in protection. Vaccine 14:1137-1142.
21. Nygren, E., J. Holmgren, and S. R. Attridge. 2008. Murine antibody responses following systemic or mucosal immunization with viable or inactivated Vibrio cholerae. Vaccine 26:6784-6790.
22. Olivier, V., G. K. Haines III, Y. Tan, and K. J. Satchell. 2007. Hemolysin and the multifunctional autoprocessing RTX toxin are virulence factors during intestinal infection of mice with Vibrio cholerae El Tor O1 strains. Infect. Immun. 75:5035-5042.
23. Olivier, V., N. H. Salzman, and K. J. Satchell. 2007. Prolonged colonization of mice by Vibrio cholerae El Tor O1 depends on accessory toxins. Infect. Immun. 75:5043-5051.
24. Qadri, F., R. Raqib, F. Ahmed, T. Rahman, C. Wenneras, S. Kumar Das, N. H. Alam, M. M. Mathan, and A.-M. Svennerholm. 2002. Increased levels of inflammatory mediators in children and adults infected with Vibrio cholerae O1 and O139. Clin. Diagn. Lab. Immunol. 9:221-229.
25. Qadri, F., E. T. Ryan, A. S. Faruque, F. Ahmed, A. I. Khan, M. M. Islam, S. M. Akramuzzaman, D. A. Sack, and S. B. Calderwood. 2003. Antigen-specific immunoglobulin A antibodies secreted from circulating B cells are an effective marker for recent local immune responses in patients with cholera: comparison to antibody-secreting cell responses and other immunological markers. Infect. Immun. 71:4808-4814.
26. Qadri, F., C. Wenneras, M. J. Albert, J. Hossain, K. Mannoor, Y. A. Begum, G. Mohi, M. A. Salam, R. B. Sack, and A. M. Svennerholm. 1997. Comparison of immune responses in patients infected with Vibrio cholerae O139 and O1. Infect. Immun. 65:3571-3576.
27. Sack, R. B., and C. E. Miller. 1969. Progressive changes of Vibrio serotypes in germ-free mice infected with Vibrio cholerae. J. Bacteriol. 99:688-695.
28. Spira, W. M., R. B. Sack, and J. L. Froehlich. 1981. Simple adult rabbit model for Vibrio cholerae and enterotoxigenic Escherichia coli diarrhea. Infect. Immun. 32:739-747.
29. Tacket, C. O., R. K. Taylor, G. Losonsky, Y. Lim, J. P. Nataro, J. B. Kaper, and M. M. Levine. 1998. Investigation of the roles of toxin-coregulated pili and mannose-sensitive hemagglutinin pili in the pathogenesis of Vibrio cholerae O139 infection. Infect. Immun. 66:692-695.
30. Taylor, R. K., V. L. Miller, D. B. Furlong, and J. J. Mekalanos. 1987. Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc. Natl. Acad. Sci. USA 84:2833-2837.
31. Ujiiye, A., M. Nakatomi, A. Utsunomiya, K. Mitsui, S. Sogame, M. Iwanaga, and K. Kobari. 1968. Experimental cholera in mice. I. First report on the oral infection. Trop. Med. 10:65-71.
32. Westphal, O., and K. Jann. 1965. Bacterial lipopolysaccharides: extraction with phenol-water and further application of the procedure. Methods Carbohydr. Chem. 5:83-91.
33. Zuckerman, J. N., L. Rombo, and A. Fisch. 2007. The true burden and risk of cholera: implications for prevention and control. Lancet Infect. Dis. 7:521-530.