Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease

European Journal of Medicinal Chemistry

Volumn 44, Issue 10, 2009, Pages 3922-3929

  Dhaneshwar, Suneela S ^a   Gairola, Neha ^a   Kandpal, Mini ^a   Vadnerkar, Gaurav ^a   Bhatt, Lokesh ^a   Rathi, Badal ^a   Kadam, S S ^a  

^a BHARATI VIDYAPEETH DEEMED UNIVERSITY   (India)

Author keywords

5 Aminosalicylic acid; Amino acids; Inflammatory bowel disease; Mutual azo prodrug

Indexed keywords

MESALAZINE; MYELOPEROXIDASE; PRODRUG; SALAZOSULFAPYRIDINE; SALICYLIC ACID; TRINITROBENZENESULFONIC ACID;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; CONTROLLED STUDY; DRUG FECES LEVEL; DRUG HALF LIFE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; ENTERITIS; FEMALE; HISTOPATHOLOGY; MALE; NONHUMAN; PARTITION COEFFICIENT; RAT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; ULCEROGENESIS;

AMINOSALICYLIC ACIDS; ANIMALS; ARTHRITIS; COLITIS; COLON; FEMALE; INFLAMMATORY BOWEL DISEASES; MALE; PEROXIDASE; PRODRUGS; RATS; RATS, WISTAR; ULCER;

EID: 67651172806     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.04.018     Document Type: Article

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