Synthesis of some novel bioactive 4-oxy/thio substituted-1H-pyrazol-5(4H)-ones via efficient cross-Claisen condensation

European Journal of Medicinal Chemistry

Volumn 44, Issue 10, 2009, Pages 3852-3857

  Venkat Ragavan, R ^a,b   Vijayakumar, V ^a   Suchetha Kumari, N ^c  

^a VIT UNIVERSITY   (India)

^b SYNGENE INTERNATIONAL LTD   (India)

^c NITTE DEEMED TO BE UNIVERSITY   (India)

Author keywords

4 Oxy thio substituted 1H pyrazol 5(4H) ones; Acid chloride; Biological activity; Cross Claisen condensation; Hydrazine hydrate; LiHMDS; Substituted oxy thio acetic acid ethyl esters

Indexed keywords

1H PYRAZOL 5(4H) ONE DERIVATIVE; 3 (BENZYLOXY) 4 PHENOXY 1H PYRAZOL 5(4H) ONE; 3 ETHYL 4 PHENOXY 1H PYRAZOL 5(4H) ONE; 3 ISOBUTYL 4 PHENYLTHIO 1H PYRAZOL 5(4H) ONE; 3 ISOPROPYL 4 PHENYLTHIO 1H PYRAZOL 5(4H) ONE; AMINOPHENAZONE; CICLOPIROXOLAMINE; DIPYRONE; ESTER; HYDRAZINE DERIVATIVE; PHENAZONE; PROPYPHENAZONE; PYRAZOLE DERIVATIVE; THIOACETIC ACID ETHYL ESTER DERIVATIVE; UNCLASSIFIED DRUG;

ADDITION REACTION; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CLAISEN CONDENSATION; CROSS CLAISEN CONDENSATION; DRUG SYNTHESIS; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; NONHUMAN; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; SUBSTITUTION REACTION;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; FUNGI; MICROBIAL SENSITIVITY TESTS; PYRAZOLONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67651165037     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.04.010     Document Type: Article

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