In vivo and ex vivo regulation of visfatin production by leptin in human and murine adipose tissue: Role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways

Endocrinology

Volumn 150, Issue 8, 2009, Pages 3530-3539

  Tan, Bee K ^a   Chen, Jing ^a   Brown, James ^a   Adya, Raghu ^a   Ramanjaneya, Manjunath ^a   Menon, Vinod ^b   Bailey, Clifford J ^c   Lehnert, Hendrik ^a,d   Randeva, Harpal S ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY HOSPITAL COVENTRY   (United Kingdom)

^c ASTON UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; SMALL INTERFERING RNA;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; EXPLANT; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OMENTUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3-L1 CELLS; ADIPOSE TISSUE; ANIMALS; BLOTTING, WESTERN; BUTADIENES; CHROMONES; CULTURE MEDIA, CONDITIONED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NITRILES; RECEPTORS, LEPTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, DNA;

EID: 67651163685     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1655     Document Type: Article

References (26)

1. Eckel RH, Grundy SM, Zimmet PZ 2005 The metabolic syndrome. Lancet 365:1415-1428
2. Kershaw EE, Flier JS 2004 Adipose tissue as an endocrine organ. J Clin Endocrinol Metab 89:2548-2556
3. Havel PJ, Kasim-Karakas S, Mueller W, Johnson PR, Gingerich RL, Stern JS 1996 Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: effects of dietary fat content and sustained weight loss. J Clin Endocrinol Metab 81:4406-4413
4. Otero M, Lago R, Lago F, Casanueva FF, Dieguez C, Gómez-Reino JJ, Gualillo O 2005 Leptin, from fat to inflammation: old questions and new insights. FEBS Lett 579:295-301
5. Frühbeck G 2006 Intracellular signaling pathways activated by leptin. Biochem J 393:7-20
6. Shimomura I, Hammer RE, Ikemoto S, Brown MS, Goldstein JL 1999 Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 401:73-76
7. Fukuhara A, Matsuda M, Nishizawa M, Segawa K, Tanaka M, Kishimoto K, Matsuki Y, Murakami M, Ichisaka T, Murakami H, Watanabe E, Takagi T, Akiyoshi M, Ohtsubo T, Kihara S, Yamashita S, Makishima M, Funahashi T, Yamanaka S, Hiramatsu R, Matsuzawa Y, Shimomura I 2005 Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 307: 426-430
8. 12 myotubes via janus kinase-2 (JAK-2) and insulin receptor substrate-2 (IRS-2) dependent pathways. Diabetologia 40:1358-1362
9. Tan BK, Chen J, Digby JE, Keay SD, Kennedy CR, Randeva HS 2006 Increased visfatin messenger ribonucleic acid and protein levels in adipose tissue and adipocytes in women with polycystic ovary syndrome: parallel increase in plasma visfatin. J Clin Endocrinol Metab 91:5022-5028
10. Chen MP, Chung FM, Chang DM, Tsai JC, Huang HF, Shin SJ, Lee YJ 2006 Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 91:295-299
11. Kim SR, Bae SK, Choi KS, Park SY, Jun HO, Lee JY, Jang HO, Yun I, Yoon KH, Kim YJ, Yoo MA, Kim KW, Bae MK 2007 Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2. Biochem Biophys Res Commun 357:150-156
12. Fried SK, Moustaid-Moussa N 2001 Culture of adipose tissue and isolated adipocytes. Methods Mol Biol 155:197-212
13. Pfaffl MW 2001 A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45
14. Van Heek M, Compton DS, France CF, Tedesco RP, Fawzi AB, Graziano MP, Sybertz EJ, Strader CD, Davis Jr HR 1997 Diet-induced obese mice develop peripheral, but not central, resistance to leptin. J Clin Invest 99:385-390
15. Mahabir S, Baer D, Johnson LL, Roth M, Campbell W, Clevidence B, Taylor PR 2007 Body mass index, percent body fat, and regional body fat distribution in relation to leptin concentrations in healthy, non-smoking postmenopausal women in a feeding study. Nutr J 6:3
16. Yang G, Ge H, Boucher A, Yu X, Li C 2004 Modulation of direct leptin signaling by soluble leptin receptor. Mol Endocrinol 18:1354-1362
17. Cohen P, Yang G, Yu X, Soukas AA, Wolfish CS, Friedman JM, Li C 2005 Induction of leptin receptor expression in the liver by leptin and food deprivation. J Biol Chem 280:10034-10039
18. van Dielen FM, van 't Veer C, Buurman WA, Greve JW 2002 Leptin and soluble leptin receptor levels in obese and weight-losing individuals. J Clin Endocrinol Metab 87:1708-1716
19. Sandeep S, Velmurugan K, Deepa R, Mohan V 2007 Serum visfatin in relation to visceral fat, obesity, and type 2 diabetes mellitus in Asian Indians. Metabolism 56:565-570
20. Haider DG, Holzer G, Schaller G, Weghuber D, Widhalm K, Wagner O, Kapiotis S, Wolzt M 2006 The adipokine visfatin is markedly elevated in obese children. J Pediatr Gastroenterol Nutr 43:548-549
21. Pagano C, Pilon C, Olivieri M, Mason P, Fabris R, Serra R, Milan G, Rossato M, Federspil G, Vettor R 2006 Reduced plasma visfatin/pre-B cell colonyenhancing factor in obesity is not related to insulin resistance in humans. J Clin Endocrinol Metab 91:3165-3170
22. Krzyzanowska K, Mittermayer F, Krugluger W, Kopp HP, Schernthaner G 2006 Increase in visfatin after weight loss induced by gastroplastic surgery. Obesity (Silver Spring) 14:1886-1889
23. Hector J, Schwarzloh B, Goehring J, Strate TG, Hess UF, Deuretzbacher G, Hansen-Algenstaedt N, Beil FU, Algenstaedt P 2007 TNF-α alters visfatin and adiponectin levels in human fat. Horm Metab Res 39:250-255
24. Murakami T, Yamashita T, Iida M, Kuwajima M, Shima K 1997 A short form of leptin receptor performs signal transduction. Biochem Biophys Res Commun 231:26-29
25. Han DC, Isono M, Chen S, Casaretto A, Hong SW, Wolf G, Ziyadeh FN 2001 Leptin stimulates type I collagen production in db/db mesangial cells: glucose uptake and TGF-β type II receptor expression. Kidney Int 59:1315-1323
26. Sahai A, Malladi P, Pan X, Paul R, Melin-Aldana H, Green RM, Whitington PF 2004 Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. Am J Physiol Gastrointest Liver Physiol 287:G1035-G1043