Inhibitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease

Platelets

Volumn 20, Issue 3, 2009, Pages 183-190

  Malik, Namita ^a   Dhawan, Veena ^a,b   Bahl, Ajay ^b   Kaul, Deepak ^a  

^a Department of Experimental Medicine Biotechnology ^*  (India)

^b POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Coronary artery disease; Ethanolic bark extract; Terminalia arjuna

Indexed keywords

CALCIUM ION; CARDIOTONIC AGENT; PADGEM PROTEIN; TERMINALIA ARJUNA EXTRACT;

ADULT; AGED; ARTICLE; AYURVEDA; BARK; CALCIUM TRANSPORT; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; HUMAN; IN VITRO STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION;

ADULT; AGED; CALCIUM; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; MALE; MIDDLE AGED; P-SELECTIN; PLANT EXTRACTS; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; TERMINALIA;

TERMINALIA ARJUNA;

EID: 67651154322     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.1080/09537100902809004     Document Type: Article

References (29)

1. Gawaz M, Langer H, May AE. Platelets in inflammation and atherogenesis. J Clin Invest 2005;115:3378-3384.
2. Katopodis JN, Kolodny L, Jy W, Horstman LL, De Marchena EJ, Tao JG, Haynes DH, Ahn YS. Platelets in inflammation and atherogenesis. J Clin Invest 2005;115:3378-3384.
3. Blann AD, Nadar SK, Lip GYH. The adhesion molecule P-selectin and cardiovascular disease. Eur Heart J 2003; 24:2166-2179.
4. Damodaran SK, Yenamandra SP. On the ethanomedical significance of the Arjun tree, Terminalia arjuna (Roxb) Wight and Arnot. J Ethanopharmacol 1987;20:173-190.
5. Kaur K, Arora S, Kumar S, Nagpal A. Antimutagenic activities of acetone and methanol fractions of Terminalia arjuna. Food Chem Toxicol 2002;40:1475-1482.
6. Ragavan B, Kanya SK. Anti-diabetic effect of T. arjuna bark extract in alloxan induced diabetic rats. Ind J Clin Biochem 2006;21:123-128.
7. Dwivedi S. Terminalia arjuna Wight and Arn - a useful drug for cardiovascular disorders. J Ethnopharmacol 2007;114: 114-129.
8. Wahal PK. A preliminary report on the inhibitory effect of abana on platelet aggregation and adhesiveness in cases of coronary heart disease and hypertension. Probe 1991;30: 312-315.
9. Mary NK, Babu BH, Padikkala J. Antiatherogenic effect of Caps HT2, a herbal Ayurvedic medicine formulation. Phytomedicine 2003;10:474-482.
10. Gensini GG. A meaningful score in system for determining the severity of Coronary heart disease. Am J Cardiol 1983; 51:606-607.
11. Friedwald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of preparative ultracentrifuge. Clin Chem 1972; 18:499-502.
12. Rao HR, Peller JD, White GJ. Measurement of ionized calcium in blood platelets with a new generation calcium indicator. Biochem Biophys Res Commun 1985;132: 652-657.
13. Sivalokanathan S, Vijyababu MR, Balasubramaniam MP. Effects of Terminalia arjuna bark extract on apoptosis of Human hepatoma cell line Hep G2. World J Gastroenterol 2006;12:1018-1024.
14. Sylviane LT, Maclouf J, Rosa JP, Gallet C, Valles G, Nurden P, Nurden AT. Abnormal tyrosine phosphorylation linked to a defective interaction between ADP and its receptor on platelets. Thromb Haemost 1998;80:463-468.
15. Davies TA, Drotts D, Weil GJ, Simons ER. Flow cytometric measurements of cytoplasmic calcium changes in human platelets. Cytometry Part A 2005;9:138-142.
16. Dietrich R, Teresa GP, Debra AP, Ted W, Harold HS, Robert G, Carl LK. Cocoa and Wine polyphenols modulates platelet activation and function. J Nutr 2000;130: 2120s-2126s.
17. Dwivedi S, Aggarwal A, Aggarwal MP, Rajpal S. Role of Terminalia arjuna in ischemic mitral regurgitation. Int J Cardiol 2005;12:391-393.
18. Dwivedi S, Agarwal MP. Antianginal and cardioprotective effects of Terminalia arjuna, an indigenous drug in coronary artery disease. J Assoc Phys Ind 1994;42:287-289.
19. Ram A, Lauria P, Gupta R, Kumar R, Sharma VS. Hypocholesterolemic effects of Terminalia arjuna tree bark. J Ethnopharmacol 1997;55:165-169.
20. Karthikeyan K, Bai BR, Gauthaman K, Sathish KS, Devaraj SN. Cardioprotective effect of the alcoholic extract of Terminalia arjuna bark in an in vivo mode of myocardial ischemic reperfusion injury. Life Sci 2003;73:2727-2739.
21. Bukhtiar SH, Nawaz Z, Saeed SA, Gilani AH. Agonist dependent differential effects of berberine in human platelet aggregation. Phytother Res 1997;12:S60-S62.
22. Nofer JR, Walter M, Kehrel B, Wierwille S, Tepel M, Seedorf U, Assmann G. HDL-3 mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositidederived second messengers 1,2 diacylglycerol and inositol 1,4,4 - tris-phosphate. Arterioscler Thromb Vasc Biol 1998;18:861-869.
23. Neiva TJ, Morais L, Polack M, Simoes CM, D'Amico EA. Effects of catechins on human blood platelet aggregation and lipid peroxidation. Phytother Res 1999;13:597-600.
24. Salvemini D, Botting R. Modulation of platelet functions by free radicals and free radical scavengers. Trends Pharmacol Sci 1993;14:36-42.
25. Kroll MH, Schafer AI. Biochemical mechanism of platelet activation. Blood 1989;74:1181.
26. Larsen E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie B. PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell 1989;59:305.
27. Antiplatelet Trialists Collaboration. Collaborative overview of randomised trials of antiplatelet therapy, I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Br Med J 1994;308:81-106.
28. Aktas B, Pozgajova M, Bergmeier W, Sunnarborg S, Offermanns S, Lee D, Wagner DD, Nieswandt B. Aspirin induces platelet receptor Shedding via ADAM17 (TACE). J Biol Chem 2005;280:39716-39722.
29. Daniel JL, Dangelmaier C, Jin J, Ashby B, Smith JB, Kunapuli SP. Molecular Basis for ADP-induced platelet activation. J Biol Chem 1998;273:2024-2029.