-
1
-
-
7844224756
-
A dose-ranging study to evaluate the safety and efficacy of abacavir alone or in combination with zidovudine and lamivudine in antiretroviral treatment-naive subjects
-
Staszewski S, Katlama C, Harrer T, et al. A dose-ranging study to evaluate the safety and efficacy of abacavir alone or in combination with zidovudine and lamivudine in antiretroviral treatment-naive subjects. AIDS. 1998;12:F197-F202.
-
(1998)
AIDS
, vol.12
-
-
Staszewski, S.1
Katlama, C.2
Harrer, T.3
-
2
-
-
0037006656
-
Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: The PENTA 5 randomised trial
-
PENTA
-
PENTA. Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: the PENTA 5 randomised trial. Lancet. 2002;359:733-740.
-
(2002)
Lancet
, vol.359
, pp. 733-740
-
-
-
3
-
-
0030903443
-
Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89
-
Faletto MB, Miller WH, Garvey EP, et al. Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89. Antimicrob Agents Chemother. 1997;41:1099-1107.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, pp. 1099-1107
-
-
Faletto, M.B.1
Miller, W.H.2
Garvey, E.P.3
-
4
-
-
0033929197
-
Population pharmacokinetics and pharmacodynamic modeling of abacavir (1592U89) from a dose-ranging, double-blind, randomized monotherapy trial with human immunodeficiency virus-infected subjects
-
Weller S, Radomski KM, Lou Y, et al. Population pharmacokinetics and pharmacodynamic modeling of abacavir (1592U89) from a dose-ranging, double-blind, randomized monotherapy trial with human immunodeficiency virus-infected subjects. Antimicrob Agents Chemother. 2000;44: 2052-2060.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 2052-2060
-
-
Weller, S.1
Radomski, K.M.2
Lou, Y.3
-
5
-
-
0032766290
-
Abacavir: Absolute bioavailability, bioequivalence of three oral formulations, and effect of food
-
Chittick GE, Gillotin C, McDowell JA, et al. Abacavir: absolute bioavailability, bioequivalence of three oral formulations, and effect of food. Pharmacotherapy. 1999;19:932-942.
-
(1999)
Pharmacotherapy
, vol.19
, pp. 932-942
-
-
Chittick, G.E.1
Gillotin, C.2
McDowell, J.A.3
-
6
-
-
0033011805
-
Safety and single-dose pharmacokinetics of abacavir (1592U89) in human immunodeficiency virus type 1-infected children
-
Hughes W, McDowell JA, Shenep J, et al. Safety and single-dose pharmacokinetics of abacavir (1592U89) in human immunodeficiency virus type 1-infected children. Antimicrob Agents Chemother. 1999;43:609-615.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 609-615
-
-
Hughes, W.1
McDowell, J.A.2
Shenep, J.3
-
7
-
-
0033113582
-
A phase I study of abacavir (1592U89) alone and in combination with other antiretroviral agents in infants and children with human immunodeficiency virus infection. AIDS Clinical Trials Group 330 Team
-
Kline MW, Blanchard S, Fletcher CV, et al. A phase I study of abacavir (1592U89) alone and in combination with other antiretroviral agents in infants and children with human immunodeficiency virus infection. AIDS Clinical Trials Group 330 Team. Pediatrics. 1999;103:e47.
-
(1999)
Pediatrics
, vol.103
-
-
Kline, M.W.1
Blanchard, S.2
Fletcher, C.V.3
-
8
-
-
0033045943
-
Safety and pharmacokinetics of abacavir (1592U89) following oral administration of escalating single doses in human immunodeficiency virus type 1-infected adults
-
Kumar PN, Sweet DE, McDowell JA, et al. Safety and pharmacokinetics of abacavir (1592U89) following oral administration of escalating single doses in human immunodeficiency virus type 1-infected adults. Antimicrob Agents Chemother. 1999;43:603-608.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 603-608
-
-
Kumar, P.N.1
Sweet, D.E.2
McDowell, J.A.3
-
9
-
-
0032772952
-
Single-dose pharmacokinetics and safety of abacavir (1592U89), zidovudine, and lamivudine administered alone and in combination in adults with human immunodeficiency virus infection
-
Wang LH, Chittick GE, McDowell JA. Single-dose pharmacokinetics and safety of abacavir (1592U89), zidovudine, and lamivudine administered alone and in combination in adults with human immunodeficiency virus infection. Antimicrob Agents Chemother. 1999;43:1708-1715.
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 1708-1715
-
-
Wang, L.H.1
Chittick, G.E.2
McDowell, J.A.3
-
10
-
-
0004137087
-
-
2nd ed. Blackwell Scientific; Oxford, UK
-
Tanner J; Growth at Adolescence. 2nd ed. Blackwell Scientific; Oxford, UK: 1962.
-
(1962)
Growth at Adolescence
-
-
Tanner, J.1
-
12
-
-
0019604592
-
Some suggestions for measuring predictive performance
-
Sheiner LB, Beal SL. Some suggestions for measuring predictive performance. J Pharmacokinet Biopharm. 1981;9:503-512.
-
(1981)
J Pharmacokinet Biopharm
, vol.9
, pp. 503-512
-
-
Sheiner, L.B.1
Beal, S.L.2
-
13
-
-
16844386944
-
Abacavir pharmacokinetics in human immunodeficiency virus-infected children ranging in age from 1 month to 16 years: A population analysis
-
Jullien V, Urien S, Chappuy H, et al. Abacavir pharmacokinetics in human immunodeficiency virus-infected children ranging in age from 1 month to 16 years: a population analysis. J Clin Pharmacol. 2005;45:257-264.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 257-264
-
-
Jullien, V.1
Urien, S.2
Chappuy, H.3
-
15
-
-
0033914965
-
Multiple-dose pharmacokinetics and pharmacodynamics of abacavir alone and in combination with zidovudine in human immunodeficiency virus-infected adults
-
McDowell JA, Lou Y, Symonds WS, et al. Multiple-dose pharmacokinetics and pharmacodynamics of abacavir alone and in combination with zidovudine in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother. 2000;44:2061-2067.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 2061-2067
-
-
McDowell, J.A.1
Lou, Y.2
Symonds, W.S.3
-
16
-
-
0035819909
-
Abacavir-lamivudinezidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial
-
Staszewski S, Keiser P, Montaner J, et al. Abacavir-lamivudinezidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: a randomized equivalence trial. JAMA. 2001;285: 1155-1163.
-
(2001)
JAMA
, vol.285
, pp. 1155-1163
-
-
Staszewski, S.1
Keiser, P.2
Montaner, J.3
-
17
-
-
0035209568
-
The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism
-
Fisher MB, Paine MF, Strelevitz TJ, et al. The role of hepatic and extrahepatic UDP-glucuronosyltransferases in human drug metabolism. Drug Metab Rev. 2001;33:273-297.
-
(2001)
Drug Metab Rev
, vol.33
, pp. 273-297
-
-
Fisher, M.B.1
Paine, M.F.2
Strelevitz, T.J.3
-
18
-
-
10444275071
-
Influence of genetic variations of ethanol-metabolizing enzymes on phenotypes of alcohol-related disorders
-
Higuchi S, Matsushita S, Masaki T, et al. Influence of genetic variations of ethanol-metabolizing enzymes on phenotypes of alcohol-related disorders. Ann N Y Acad Sci. 2004;1025:472-480.
-
(2004)
Ann N Y Acad Sci
, vol.1025
, pp. 472-480
-
-
Higuchi, S.1
Matsushita, S.2
Masaki, T.3
-
19
-
-
0037184841
-
Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance
-
Miners JO, McKinnon RA, Mackenzie PI. Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance. Toxicology. 2002;181-182:453-456.
-
(2002)
Toxicology
-
-
Miners, J.O.1
McKinnon, R.A.2
Mackenzie, P.I.3
-
20
-
-
0033645752
-
Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: Ethnic diversity of alleles and potential clinical significance
-
Bhasker CR, McKinnon W, Stone A, et al. Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance. Pharmacogenetics. 2000;10:679-685.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 679-685
-
-
Bhasker, C.R.1
McKinnon, W.2
Stone, A.3
-
21
-
-
12244271026
-
Haplotype structure of the UDPglucuronosyltransferase 1A1 promoter in different ethnic groups
-
Innocenti F, Grimsley C, Das S, et al. Haplotype structure of the UDPglucuronosyltransferase 1A1 promoter in different ethnic groups. Pharmacogenetics. 2002;12:725-733.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 725-733
-
-
Innocenti, F.1
Grimsley, C.2
Das, S.3
-
22
-
-
0030851067
-
Polymorphism of ADH and ALDH genes among four ethnic groups in China and effects upon the risk for alcoholism
-
Shen YC, Fan JH, Edenberg HJ, et al. Polymorphism of ADH and ALDH genes among four ethnic groups in China and effects upon the risk for alcoholism. Alcohol Clin Exp Res. 1997;21:1272-1277.
-
(1997)
Alcohol Clin Exp Res
, vol.21
, pp. 1272-1277
-
-
Shen, Y.C.1
Fan, J.H.2
Edenberg, H.J.3
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