Expression analysis of the Aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues

Journal of Biochemistry

Volumn 146, Issue 1, 2009, Pages 51-60

  Hirakawa, Haruka ^a   Sawada, Hiroshi ^a   Yamahama, Yumi ^b   Takikawa, Shin Ichiro ^c   Shintaku, Haruo ^d   Hara, Akira ^e   Mase, Keisuke ^f   Kondo, Tomoyoshi ^g   Iino, Teruhiko ^a  

^a NIHON UNIVERSITY   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KITASATO UNIVERSITY   (Japan)

^d OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^f NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^g WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

AKR1B1; AKR1C3; Aldo keto reductase; BH4 deficiency; SPR deficiency

Indexed keywords

3ALPHA HYDROXYSTEROID DEHYDROGENASE; ALDEHYDE REDUCTASE; AROMATIC AMINO ACID; DYSPROPTERIN; NEUROTRANSMITTER; OXIDOREDUCTASE; OXYGENASE; SEPIAPTERIN REDUCTASE; TETRAHYDROBIOPTERIN;

ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; ENZYME ANALYSIS; ENZYME DEFICIENCY; HUMAN; HUMAN TISSUE; HYPERPHENYLALANINEMIA; KNOCKOUT MOUSE; LIVER; LOCOMOTION; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN EXPRESSION;

3-HYDROXYSTEROID DEHYDROGENASES; AGED; ALCOHOL OXIDOREDUCTASES; ALDEHYDE REDUCTASE; ANIMALS; BIOPTERIN; BRAIN; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; KIDNEY; LIVER; LUNG; MALE; MICE; MICE, INBRED BALB C; MIDDLE AGED; MYOCARDIUM; ORGAN SPECIFICITY;

MUS;

EID: 67651151423     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvp042     Document Type: Article

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