Mechanisms for the initiation of human atrial fibrillation

Heart Rhythm

Volumn 6, Issue 8 SUPPL., 2009, Pages

  Krummen, David E ^a   Narayan, Sanjiv M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Action potential duration; Atrial fibrillation; Electrical restitution; Human; Remodeling; Repolarization alternans

Indexed keywords

ACTION POTENTIAL; ARTICLE; HEART ATRIUM FIBRILLATION; HEART CONDUCTION; HEART MUSCLE FIBROSIS; HEART REPOLARIZATION; PRIORITY JOURNAL; SUPRAVENTRICULAR PREMATURE BEAT;

ACTION POTENTIALS; ANIMALS; ATRIAL FIBRILLATION; CICATRIX; DOGS; FIBROSIS; HUMANS; MYOCARDIUM;

EID: 67651147983     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2009.03.004     Document Type: Article

References (46)

1. Nattel S. New ideas about atrial fibrillation 50 years on. Nature 415 (2002) 219-226
2. Calkins H., Brugada J., Packer D., et al. HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. A report of the Heart Rhythm Society (HRS) Task Force on catheter and surgical ablation of atrial fibrillation.European Heart Rhythm Association (EHRA); European Cardiac Arrhythmia Scoiety (ECAS); American College of Cardiology (ACC); American Heart Association (AHA); Society of Thoracic Surgeons (STS). Heart Rhythm 4 (2007) 816-861
3. Haissaguerre M., Jais P., Shah D.C., et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med 339 (1998) 659-666
4. Haissaguerre M., Hocini M., Sanders P., et al. Catheter ablation of long-lasting Persistent atrial fibrillation: clinical outcome and mechanisms of subsequent arrhythmias. J Cardiovasc Electrophysiol 16 (2005) 1138-1147
5. Oral H., Chugh A., Good E., et al. Radiofrequency catheter ablation of chronic atrial fibrillation guided by complex electrograms. Circulation 115 (2007) 2606-2612
6. Singh B.N., Singh S.N., Reda D.J., et al. Amiodarone versus sotalol for atrial fibrillation. N Engl J Med 352 (2005) 1861-1872
7. Vaquero M., Calvo D., and Jalife J. Cardiac fibrillation: from ion channels to rotors in the human heart. Heart Rhythm 5 6 (Jun 2008) 872-879
8. Waldo A.L., and Feld G.K. Inter-relationships of atrial fibrillation and atrial flutter mechanisms and clinical implications. J Am Coll Cardiol 51 (2008) 779-786
9. Ho S.Y., and Sanchez-Quintana D. The importance of atrial structure and fibers. Clin Anat 22 1 (Jan 2009) 52-63
10. Chang S.L., Tai C.T., Lin Y.J., et al. Biatrial substrate properties in patients with atrial fibrillation. J Cardiovasc Electrophysiol 18 (2007) 1134-1139
11. Allessie M.A., Ausma J., and Schotten U. Electrical, contractile and structural remodeling during atrial fibrillation. Cardiovasc Res 54 (2002) 230-246
12. Konings K., Kirchhof C., Smeets J., Wellens H., Penn O., and Allessie M. High-density mapping of electrically induced atrial fibrillation in humans. Circulation 89 (1994) 1665-1680
13. Cox J.L. The central controversy surrounding the interventional-surgical treatment of atrial fibrillation. J Thorac Cardiovasc Surg 129 (2005) 1-4
14. Wu T.-J., Doshi R.N., Huang H.-L.A., et al. Simultaneous biatrial computerized mapping during permanent atrial fibrillation in patients with organic heart disease. J Cardiovasc Electrophysiol 13 (2002) 571-577
15. Lazar S., Dixit S., Marchlinski F.E., et al. Presence of left-to-right atrial frequency gradient in paroxysmal but not persistent atrial fibrillation in humans. Circulation 110 (2004) 3181-3186
16. Sanders P., Berenfeld O., Hocini M., et al. Spectral analysis identifies sites of high-frequency activity maintaining atrial fibrillation in humans. Circulation 112 (2005) 789-797
17. Narayan S.M., Krummen D.E., Kahn A.M., et al. Evaluating fluctuations in human atrial fibrillatory cycle length using monophasic action potentials. Pacing Clin Electrophysiol 29 (2006) 1209-1218
18. Ng J., Kadish A.H., and Goldberger J.J. Technical considerations for dominant frequency analysis. J Cardiovasc Electrophysiol 18 (2007) 757-764
19. Jahangir A., Lee V., Friedman P.A., et al. Long-term progression and outcomes with aging in patients with lone atrial fibrillation: a 30-year follow-up study. Circulation 115 (2007) 3050-3056
20. Everett IV T.H., Li H., Mangrum J.M., et al. Electrical, morphological, and ultrastructural remodeling and reverse remodeling in a canine model of chronic atrial fibrillation. Circulation (2000) 1454-1460
21. Akar J.G., Everett T.H.I., Kok L.C., et al. Effect of electrical and structural remodeling on spatiotemporal organization in acute and persistent atrial fibrillation. J. Cardiovasc Electrophysiol 13 (2002) 1027-1034
22. Fynn S., Todd D., Hobbs W., et al. Clinical evaluation of a policy of early repeated internal cardioversion for recurrence of atrial fibrillation. J Cardiovasc Electrophysiol 13 (2002) 135-141
23. Dobrev D., Graf E., Wettwer E., et al. Molecular basis of downregulation of G-protein-coupled inward rectifying K(+) current (I(K,ACh) in chronic human atrial fibrillation: decrease in GIRK4 mRNA correlates with reduced I(K,ACh) and muscarinic receptor-mediated shortening of action potentials. Circulation 104 (2001) 2551-2557
24. Sharifov O.F., Fedorov V.V., Beloshapko G.G., et al. Roles of adrenergic and cholinergic stimulation in spontaneous atrial fibrillation in dogs. J Am Coll Cardiol 43 (2004) 483-490
25. Patterson E., Lazzara R., Szabo B., et al. Sodium-calcium exchange initiated by the Ca2+ transient: an arrhythmia trigger within pulmonary veins. J Am Coll Cardiol 47 (2006) 1196-1206
26. Workman A.J., Kane K.A., and Rankin A.C. The contribution of ionic currents to changes in refractoriness of human atrial myocytes associated with chronic atrial fibrillation. Cardiovasc Res 52 (2001) 226-235
27. El-Armouche A., Boknik P., Eschenhagen T., et al. Molecular determinants of altered Ca2+ handling in human chronic atrial fibrillation. Circulation 114 (2006) 670-680
28. Lemola K., Chartier D., Yeh Y.H., et al. Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia. Circulation 117 (2008) 470-477
29. Lellouche N., Buch E., Celigoj A., et al. Functional characterization of atrial electrograms in sinus rhythm delineates sites of parasympathetic innervation in patients with paroxysmal atrial fibrillation. J Am Coll Cardiol 50 (2007) 1324-1331
30. Verma A., Saliba W., Lakkireddy D., et al. Vagal responses induced by endocardial left atrial autonomic ganglion stimulation before and after pulmonary vein antrum isolation for atrial fibrillation. Heart Rhythm 4 (2007) 1177-1182
31. Jais P., Peng J.T., Shah D.C., et al. Left ventricular diastolic dysfunction in patients with so-called lone atrial fibrillation. J Cardiovasc Electrophysiol 11 (2000) 623-625
32. Bode F., Sachs F., and Franz M.R. Tarantula peptide inhibits atrial fibrillation. Nature 409 (2001) 35-36
33. Weiss J.N., Karma A., Shiferaw Y., et al. From pulsus to pulseless: the saga of cardiac alternans (review). Circ Res 98 (2006) 1244-1253
34. Sanders P., Morton J.B., Kistler P.M., et al. Electrophysiological and electroanatomic characterization of the atria in sinus node disease: evidence of diffuse atrial remodeling. Circulation 109 (2004) 1514-1522
35. Li D., Fareh S., Leung T.K., et al. Promotion of atrial fibrillation by heart failure in dogs: atrial remodelling of a different sort. Circulation 100 (1999) 87-95
36. Li D., Zhang L., Kneller J., et al. Potential ionic mechanism for repolarization differences between canine right and left atrium. Circ Res 88 (2001) 1168-1175
37. Narayan S.M., Kazi D., Krummen D.E., et al. Repolarization and activation restitution near human pulmonary veins and atrial fibrillation initiation: a mechanism for the initiation of atrial fibrillation by premature beats. J Am Coll Cardiol 52 (2008) 1222-1230
38. Markides V., Schilling R.J., Yen Ho S., et al. Characterization of left atrial activation in the intact human heart. Circulation 107 (2003) 733-739
39. Roberts-Thomson K.C., Stevenson I.H., Kistler P.M., et al. Anatomically determined functional conduction delay in the posterior left atrium relationship to structural heart disease. J Am Coll Cardiol 51 (2008) 856-862
40. Gong Y., Xie F., Stein K., et al. Mechanism underlying initiation of paroxysmal atrial flutter/atrial fibrillation by ectopic foci: a simulation study. Circulation 115 (2007) 2094-2102
41. Franz M.R. The electrical restitution curve revisited: steep or flat slope-which is better?. J Cardiovasc Electrophysiol 14 (2003) S140-S147
42. Narayan S.M., Bode F., Karasik P.L., et al. Alternans of atrial action potentials as a precursor of atrial fibrillation. Circulation 106 (2002) 1968-1973
43. Laurita K.R., and Rosenbaum D.S. Mechanisms and potential therapeutic targets for ventricular arrhythmias associated with impaired cardiac calcium cycling. J Mol Cell Cardiol 44 (2008) 31-43
44. Narayan S.M., Bayer J., Lalani G., et al. Action potential dynamics explain arrhythmic vulnerability in human heart failure: a clinical and modeling study implicating abnormal calcium handling. J Am Coll Cardiol 52 (2008) 1782-1792
45. Ohashi N., Mitamura H., Tanimoto K., et al. A comparison between calcium channel blocking drugs with different potencies for T- and L-type channels in preventing atrial electrical remodeling. J Cardiovasc Pharmacol 44 (2004) 386-392
46. Mahajan A., Sato D., Shiferaw Y., et al. Modifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics. Biophys J 94 (2008) 411-423