Functional Characterization of Atrial Electrograms in Sinus Rhythm Delineates Sites of Parasympathetic Innervation in Patients With Paroxysmal Atrial Fibrillation

Journal of the American College of Cardiology

Volumn 50, Issue 14, 2007, Pages 1324-1331

  Lellouche, Nicolas ^a   Buch, Eric ^a   Celigoj, Andrew ^a   Siegerman, Carin ^a   Cesario, David ^a   De Diego, Carlos ^a   Mahajan, Aman ^a   Boyle, Noel G ^a   Wiener, Isaac ^a   Garfinkel, Alan ^a   Shivkumar, Kalyanam ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROGRAPHY; FEMALE; HEART ATRIUM FIBRILLATION; HUMAN; MALE; PRIORITY JOURNAL; SINUS RHYTHM;

ADENOSINE; ANTI-ARRHYTHMIA AGENTS; ATRIAL FIBRILLATION; CATHETER ABLATION; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PARASYMPATHETIC NERVOUS SYSTEM; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SINOATRIAL NODE;

EID: 34548825775     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2007.03.069     Document Type: Article

References (30)

1. Wang Z., Page P., and Nattel S. Mechanism of flecainide's antiarrhythmic action in experimental atrial fibrillation. Circ Res 71 (1992) 271-287
2. Chen Y.J., Chen S.A., Tai C.T., et al. Role of atrial electrophysiology and autonomic nervous system in patients with supraventricular tachycardia and paroxysmal atrial fibrillation. J Am Coll Cardiol 32 (1998) 732-738
3. Pappone C., Santinelli V., Manguso F., et al. Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation. Circulation 109 (2004) 327-334
4. Konings K.T., Smeets J.L., Penn O.C., Wellens H.J., and Allessie M.A. Configuration of unipolar atrial electrograms during electrically induced atrial fibrillation in humans. Circulation 95 (1997) 1231-1241
5. Nademanee K., McKenzie J., Kosar E., et al. A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate. J Am Coll Cardiol 43 (2004) 2044-2053
6. Pachon M.J., Pachon M.E., Pachon M.J., et al. A new treatment for atrial fibrillation based on spectral analysis to guide the catheter RF-ablation. Europace 6 (2004) 590-601
7. Po S.S., Scherlag B.J., Yamanashi W.S., et al. Experimental model for paroxysmal atrial fibrillation arising at the pulmonary vein-atrial junctions. Heart Rhythm 3 (2006) 201-208
8. Pachon J.C., Pachon E.I., Pachon J.C., et al. "Cardioneuroablation"-new treatment for neurocardiogenic syncope, functional AV block and sinus dysfunction using catheter RF-ablation. Europace 7 (2005) 1-13
9. Belardinelli L., Giles W.R., and West A. Ionic mechanisms of adenosine actions in pacemaker cells from rabbit heart. J Physiol 405 (1988) 615-633
10. Josephson M.E. Clinical Cardiac Electrophysiology: Techniques and Interpretation. 2nd edition (1993), Lea & Febiger, Philadelphia, PA
11. Reddy C.P., Damato A.N., Akhtar M., et al. Time dependent changes in the functional properties of the atrioventricular conduction system in man. Circulation 52 (1975) 1012-1022
12. Jacquemet V., Virag N., Ihara Z., et al. Study of unipolar electrogram morphology in a computer model of atrial fibrillation. J Cardiovasc Electrophysiol 14 (2003) S172-S179
13. Courtemanche M., Ramirez R.J., and Nattel S. Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model. Am J Physiol 275 (1998) H301-H321
14. Kneller J., Zou R., Vigmond E.J., Wang Z., Leon L.J., and Nattel S. Cholinergic atrial fibrillation in a computer model of a two-dimensional sheet of canine atrial cells with realistic ionic properties. Circ Res 90 (2002) E73-E87
15. Breiman L. Classification and Regression Trees (1984), Wadsworth International Group, Belmont, CA
16. Kalifa J., Tanaka K., Zaitsev A.V., et al. Mechanisms of wave fractionation at boundaries of high-frequency excitation in the posterior left atrium of the isolated sheep heart during atrial fibrillation. Circulation 113 (2006) 626-633
17. Rostock T., Rotter M., Sanders P., et al. High-density activation mapping of fractionated electrograms in the atria of patients with paroxysmal atrial fibrillation. Heart Rhythm 3 (2006) 27-34
18. Sanders P., Morton J.B., Kistler P.M., et al. Electrophysiological and electroanatomical characterization of the atria in sinus node disease: evidence of diffuse atrial remodeling. Circulation 109 (2004) 1514-1522
19. Hughes H.C., Furman S., Brownlee R.R., and DelMarco C. Simultaneous atrial and ventricular electrogram transmission via a specialized single lead system. Pacing Clin Electrophysiol 7 (1984) 1195-1201
20. Gardner P.I., Ursell P.C., Fenoglio Jr. J.J., and Wit A.L. Electrophysiologic and anatomical basis for fractionated electrograms recorded from healed myocardial infarcts. Circulation 72 (1985) 596-611
21. Marcus G.M., Yang Y., Varosy P.D., et al. Regional left atrial voltage in patients with atrial fibrillation. Heart Rhythm 4 (2007) 138-144
22. Spach M.S., and Dolber P.C. Relating extracellular potentials and their derivatives to anisotropic propagation at a microscopic level in human cardiac muscle. Evidence for electrical uncoupling of side-to-side fiber connections with increasing age. Circ Res 58 (1986) 356-371
23. Schauerte P., Scherlag B.J., Pitha J., et al. Catheter ablation of cardiac autonomic nerves for prevention of vagal atrial fibrillation. Circulation 102 (2000) 2774-2780
24. Allessie M.A. Atrial electrophysiologic remodeling: another vicious circle?. J Cardiovasc Electrophysiol 9 (1998) 1378-1393
25. Schauerte P., Scherlag B.J., Patterson E., et al. Focal atrial fibrillation: experimental evidence for a pathophysiologic role of the autonomic nervous system. J Cardiovasc Electrophysiol 12 (2001) 592-599
26. Pott L. On the time course of the acetylcholine-induced hyperpolarization in quiescent guinea-pig atria. Pflugers Arch 380 (1979) 71-77
27. Dhamoon A.S., and Jalife J. The inward rectifier current (IK1) controls cardiac excitability and is involved in arrhythmogenesis. Heart Rhythm 2 (2005) 316-324
28. Duncan J.C., and Fletcher W.H. Alpha 1 connexin (connexin43) gap junctions and activities of cAMP-dependent protein kinase and protein kinase C in developing mouse heart. Dev Dyn 223 (2002) 96-107
29. George E.E., Romano F.D., and Dobson Jr. J.G. Adenosine and acetylcholine reduce isoproterenol-induced protein phosphorylation of rat myocytes. J Mol Cell Cardiol 23 (1991) 749-764
30. Dillon S.M., Allessie M.A., Ursell P.C., and Wit A.L. Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of subacute canine infarcts. Circ Res 63 (1988) 182-206