Serum levels of gamma-glutamyl transferase are associated with markers of nocturnal hypoxemia in a general adult population

Clinica Chimica Acta

Volumn 407, Issue 1-2, 2009, Pages 67-71

  Gude, Francisco ^a   Rey Garcia, Jesús ^b   Fernandez Merino, Carmen ^b   Meijide, Luis ^b   García Ortiz, Luis ^c   Zamarron, Carlos ^a   Gonzalez Quintela, Arturo ^a  

^a University Hospital of Santiago de Compostela   (Spain)

^b Primary Care Center of A Estrada   (Spain)

^c Biomedical Research Institute of Salamanca IBSAL   (Spain)

Author keywords

Gamma glutamyl transferase; Hypoxemia; Metabolic syndrome; Non alcoholic fatty liver disease; Sleep disordered breathing

Indexed keywords

CYTOKINE; GAMMA GLUTAMYLTRANSFERASE; INTERLEUKIN 6; LIVER ENZYME; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; AGING; ALCOHOL CONSUMPTION; ARTERIAL OXYGEN SATURATION; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; HYPOXEMIA; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NOCTURNAL HYPOXEMIA; POLYSOMNOGRAPHY; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PULSE OXIMETRY; SEX DIFFERENCE; SLEEP; SMOKING;

ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; ANOXIA; ARTERIES; BIOLOGICAL MARKERS; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; INTERLEUKIN-6; MALE; METABOLIC SYNDROME X; MIDDLE AGED; MULTIVARIATE ANALYSIS; OXYGEN; REGRESSION ANALYSIS; SEX DISTRIBUTION; SMOKING; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 67651108994     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2009.06.034     Document Type: Article

References (32)

1. Goldberg D.M. Structural, functional, and clinical aspects of gamma-glutamyltransferase. CRC Crit Rev Clin Lab Sci 12 (1980) 1-58
2. Conigrave K.M., Davies P., Haber P., and Whitfield J.B. Traditional markers of excessive alcohol use. Addiction 98 Suppl. 2 (2003) 31-43
3. Niemela O. Biomarkers in alcoholism. Clin Chim Acta 377 (2007) 39-49
4. Cushman P., Jacobson G., Barboriak J.J., and Anderson A.J. Biochemical markers for alcoholism: sensitivity problems. Alcohol Clin Exp Res 8 (1984) 253-257
5. Nannipieri M., Gonzales C., and Baldi S. Mexico City diabetes study. Liver enzymes, the metabolic syndrome, and incident diabetes: the Mexico City diabetes study. Diabetes Care 28 (2005) 1757-1762
6. Jo S.K., Won-Young L., Eun-Jung R., Jong-Chul W., Chan-Hee J., and Cheol-Young P. Serum γ-glutamyl transferase activity predicts future development of metabolic syndrome defined by 2 different criteria. Clin Chim Acta 403 (2009) 234-240
7. Lee D.H., Silventoinen K., Hu G., et al. Serum gamma-glutamyltransferase predicts non-fatal myocardial infarction and fatal coronary heart disease among 28,838 middle-aged men and women. Eur Heart J 27 (2006) 2170-2176
8. Jousilahti P., Rastenyte D., and Tuomilehto J. Serum gamma-glutamyl transferase, self-reported alcohol drinking, and the risk of stroke. Stroke 31 (2000) 1851-1855
9. Lee D.H., Jacobs D.R., Gross M., et al. Gamma glutamyltransferase is a predictor of incident diabetes and hypertension: the CARDIA study. Clin Chem 49 (2003) 1358-1366
10. Hotamisligil G.S. Inflammation and metabolic disorders. Nature 444 (2006) 860-867
11. de Alwis N.M. Day CP. Non-alcoholic fatty liver disease: the mist gradually clears. J. Hepatol. 48 Suppl 1 (2008) S104-S112
12. Tanné F., Gagnadoux F., Chazouillères O., et al. Chronic liver injury during obstructive sleep apnea. Hepatology 41 (2005) 1290-1296
13. Barceló A., Barbé F., de la Peña M., et al. Antioxidant status in patients with sleep apnoea and impact of continuous positive airway pressure treatment. Eur Respir J 27 (2006) 756-760
14. González-Quintela A., Gude F., Boquete O., et al. Association of alcohol consumption with total serum immunoglobulin E levels and allergic sensitization in an adult population-based survey. Clin Exp Allergy 33 (2003) 199-205
15. Rey-García J., Fernández-Merino M.C., Meijide Calvo L., et al. Prevalence of respiratory disorders during sleep and associated factors. Aten Primaria 39 (2007) 255-259
16. Gual A., Martos A.R., Lligona A., and Llopis J.J. Does the concept of a standard drink apply to viticultural societies?. Alcohol Alcohol 34 (1999) 153-160
17. Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults. Executive summary of third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 285 (2001) 2486-2497
18. Gonzalez-Quintela A., Alende R., Gude F., et al. Serum levels of immunoglobulins (IgG, IgA, IgM) in a general adult population and their relationship with alcohol consumption, smoking and common metabolic abnormalities. Clin Exp Immunol 151 (2008) 42-50
19. Gonzalez-Quintela A., Campos J., Loidi L., Quinteiro C., Perez L.F., and Gude F. Serum TNF-alpha levels in relation to alcohol consumption and common TNF gene polymorphisms. Alcohol 42 (2008) 513-518
20. Rechtschaffen A., and Kales A. A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects. BIS/BRI. Los Angeles (1968)
21. De Boor C.A. A practical guide to splines. Revised Edition (2001), Springer-Verlag, New-York
22. Wood S.N. Generalized additive models: an introduction with R (2006), Chapman and Hall/CRC, New York
23. Norman D., Bardwell W.A., Arosemena F., et al. Serum aminotransferase levels are associated with markers of hypoxia in patients with obstructive sleep apnea. Sleep 31 (2008) 121-126
24. Day C.P., and James O.F. Steatohepatitis: a tale of two "hits"?. Gastroenterology 114 (1998) 842-845
25. Te Sligte K., Bourass I., Sels J.P., Driessen A., Stockbrugger R.W., and Koek G.H. Non-alcoholic steatohepatitis: review of a growing medical problem. Eur J Intern Med 15 (2004) 10-21
26. Lavie L., Vishnevsky A., and Lavie P. Evidence for lipid peroxidation in obstructive sleep apnea. Sleep 27 (2004) 123-128
27. Savransky V., Nanayakkara A., Vivero A., et al. Chronic intermittent hypoxia predisposes to liver injury. Hepatology 45 (2007) 1007-1013
28. Savransky V., Bevans S., Nanayakkara A., et al. Chronic intermittent hypoxia causes hepatitis in a mouse model of diet-induced fatty liver. Am J Physiol Gastrointest Liver Physiol 293 (2007) G871-G877
29. Nicolaou C., Chatzipanagiotou S., Tzivos D., Tzavellas E.O., Boufidou F., and Liappas I.A. Serum cytokine concentrations in alcohol-dependent individuals without liver disease. Alcohol 32 (2004) 243-247
30. Lee D.H., Blomhoff R., and Jacobs Jr. D.R. Is serum gamma glutamyltransferase a marker of oxidative stress?. Free Radic Res 38 (2004) 535-539
31. Lemmens P.H. The alcohol content of self-report and 'standard' drinks. Addiction 89 (1994) 593-601
32. Mateos R., Paramo M., Carrera I., and Rodríguez-López A. Alcohol consumption in a Southern European Region (Galicia, Spain). Substance Use and Misuse 37 (2002) 1957-1973