Polymer supported synthesis of aminooxyalkylated oligonucleotides, and some applications in the fabrication of microarrays

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 15, 2009, Pages 5442-5450

  Sethi, D ^a   Patnaik, S ^b   Kumar, A ^a   Gandhi, R P ^c   Gupta, K C ^a,d   Kumar, P ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b UNIVERSITY OF RHODE ISLAND   (United States)

^c UNIVERSITY OF DELHI   (India)

^d CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Aminooxyalkyl oligonucleotides; Base mismatch; Disease diagnosis; Hybridization; Microarray; Solid phase synthesis

Indexed keywords

N (2,3 DIHYDROXYPROPYL)ACETAMIDE 2 N (9 FLUORENYLMETHYLOXYCARBONYL)OXYAMINE; N (9 FLUORENYLMETHYLOXYCARBONYL) 2 AMINOOXYACETIC ACID; N [2 HYDROXY 3 (4,4' DIMETHOXYTRITYLOXY)PROPYL]ACETAMIDE 2 N (9 FLUORENYLMETHYLOXYCARBONYL)OXYAMINE; OLIGOMER; OLIGONUCLEOTIDE; POLYMER; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; AUTOMATION; BACTERIUM DETECTION; CHEMICAL MODIFICATION; DNA MICROARRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; POLYMERASE CHAIN REACTION; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID; SYNTHESIS; TEMPERATURE; THERMOSTABILITY; TIME; TYPHOID FEVER;

ALKYLATION; AMINATION; BASE PAIR MISMATCH; BIOSENSING TECHNIQUES; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGONUCLEOTIDES; POLYMERS; SALMONELLA TYPHI; TYPHOID FEVER;

BACTERIA (MICROORGANISMS);

EID: 67651108970     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.06.038     Document Type: Article

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