메뉴 건너뛰기




Volumn 407, Issue 1-2, 2009, Pages 51-57

Impact of excess aldosterone on glucose homeostasis in adult male rat

Author keywords

Aldosteronism; Glucose homeostasis; GLUT2; GLUT4; Skeletal muscle and liver; Type II diabetes

Indexed keywords

ALDOSTERONE; COMPLEMENTARY DNA; GLUCOSE; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 4; MESSENGER RNA; RNA;

EID: 67651091717     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2009.06.030     Document Type: Article
Times cited : (33)

References (66)
  • 1
    • 0036270751 scopus 로고    scopus 로고
    • Regulated transport of the glucose transporter GLUT4
    • Bryant N.J., Govers R., and James D.E. Regulated transport of the glucose transporter GLUT4. Nat Rev Mol Cell Biol 3 (2002) 267-277
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 267-277
    • Bryant, N.J.1    Govers, R.2    James, D.E.3
  • 2
    • 18844369302 scopus 로고    scopus 로고
    • Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options
    • Srivastava S.K., Ramana K.V., and Bhatnagar A. Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options. Endocr Rev 26 (2005) 380-392
    • (2005) Endocr Rev , vol.26 , pp. 380-392
    • Srivastava, S.K.1    Ramana, K.V.2    Bhatnagar, A.3
  • 4
    • 0141790115 scopus 로고    scopus 로고
    • The effects of hyperglycemia on glucose disposal and insulin signal transduction in skeletal muscles
    • Zierath J.R., and Kawano Y. The effects of hyperglycemia on glucose disposal and insulin signal transduction in skeletal muscles. Res Clin Endocrinol Metabol 17 (2003) 385-398
    • (2003) Res Clin Endocrinol Metabol , vol.17 , pp. 385-398
    • Zierath, J.R.1    Kawano, Y.2
  • 5
    • 0024237258 scopus 로고
    • Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans
    • Baron A.D., Brechtel G., Wallace P., and Edelman S.V. Rates and tissue sites of non-insulin- and insulin-mediated glucose uptake in humans. Am J Physiol 255 (1988) E769-E774
    • (1988) Am J Physiol , vol.255
    • Baron, A.D.1    Brechtel, G.2    Wallace, P.3    Edelman, S.V.4
  • 6
    • 0038223536 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes mellitus: metabolic and molecular implications for identifying diabetes genes
    • De Fronzo R.A. Pathogenesis of type 2 diabetes mellitus: metabolic and molecular implications for identifying diabetes genes. Diabetes 5 (1997) 117-269
    • (1997) Diabetes , vol.5 , pp. 117-269
    • De Fronzo, R.A.1
  • 7
    • 0032797852 scopus 로고    scopus 로고
    • Regulation of glucose production by the liver
    • Nordlie R.C., Foster J.D., and Lange A.J. Regulation of glucose production by the liver. Annu Rev Nutr 19 (1999) 379-406
    • (1999) Annu Rev Nutr , vol.19 , pp. 379-406
    • Nordlie, R.C.1    Foster, J.D.2    Lange, A.J.3
  • 8
    • 0035787305 scopus 로고    scopus 로고
    • Intracellular organization of insulin signaling and GLUT 4 translocation
    • Watson R.T., and Pesin J.E. Intracellular organization of insulin signaling and GLUT 4 translocation. Recent prog Horm Res 56 (2001) 175-193
    • (2001) Recent prog Horm Res , vol.56 , pp. 175-193
    • Watson, R.T.1    Pesin, J.E.2
  • 9
    • 67651110841 scopus 로고    scopus 로고
    • Muscle
    • Brooks/Cole-Thomson Learning, Pacific groove, CA, USA
    • Rhodes R. Muscle. Human physiology 4th edition (2003), Brooks/Cole-Thomson Learning, Pacific groove, CA, USA 476-519
    • (2003) Human physiology 4th edition , pp. 476-519
    • Rhodes, R.1
  • 10
    • 0023743171 scopus 로고
    • Mineralocorticoid action is enzyme, not receptor mediated
    • Funder J.W., Pearce P.T., Smith R., and Smith A.I. Mineralocorticoid action is enzyme, not receptor mediated. Science 242 (1988) 583-585
    • (1988) Science , vol.242 , pp. 583-585
    • Funder, J.W.1    Pearce, P.T.2    Smith, R.3    Smith, A.I.4
  • 11
    • 0027193909 scopus 로고
    • Characterization of the interaction of the human mineralocorticoid receptor with hormone response elements
    • Lombus B., Binart N., Oblin M.E., Joulin V., and Baulieu E.E. Characterization of the interaction of the human mineralocorticoid receptor with hormone response elements. Biochem J (1993) 577-583
    • (1993) Biochem J , pp. 577-583
    • Lombus, B.1    Binart, N.2    Oblin, M.E.3    Joulin, V.4    Baulieu, E.E.5
  • 12
    • 0025787868 scopus 로고
    • Characterization of the interaction of the human mineralocorticoid receptor expressed in the baculovirus system
    • Binart N., Lombums M., Rafestin-Oblin M.E., and Baulieu E.E. Characterization of the interaction of the human mineralocorticoid receptor expressed in the baculovirus system. Proc Natl Acad Sci 88 (1991) 10681-10685
    • (1991) Proc Natl Acad Sci , vol.88 , pp. 10681-10685
    • Binart, N.1    Lombums, M.2    Rafestin-Oblin, M.E.3    Baulieu, E.E.4
  • 13
    • 22544466731 scopus 로고    scopus 로고
    • The new biology of aldosterone
    • Connell J.M., and Davies E. The new biology of aldosterone. J Endocrinol 186 (2005) 1-20
    • (2005) J Endocrinol , vol.186 , pp. 1-20
    • Connell, J.M.1    Davies, E.2
  • 14
    • 50549212658 scopus 로고
    • Clinical characteristics of primary aldosteronism from an analysis of 145 cases
    • Conn J.W., Knopf R.F., and Nesbit R.M. Clinical characteristics of primary aldosteronism from an analysis of 145 cases. Am J Surg 107 (1964) 159-172
    • (1964) Am J Surg , vol.107 , pp. 159-172
    • Conn, J.W.1    Knopf, R.F.2    Nesbit, R.M.3
  • 16
    • 15944366224 scopus 로고    scopus 로고
    • The renin-angiotensin-aldosterone system. Glucose metabolism and diabetes
    • Giacchetti G., Sechi L.A., Rilli S., and Carey R.M. The renin-angiotensin-aldosterone system. Glucose metabolism and diabetes. Trends Endocrinol and Metab 16 (2005) 120-126
    • (2005) Trends Endocrinol and Metab , vol.16 , pp. 120-126
    • Giacchetti, G.1    Sechi, L.A.2    Rilli, S.3    Carey, R.M.4
  • 17
    • 0035986720 scopus 로고    scopus 로고
    • Aldosterone impairs insulin responsiveness in U-937 human promonocytic cells via the downregulation of its own receptor
    • Campion J., Maestro B., Molero S., Davila N., Carranza M.C., and Calle C. Aldosterone impairs insulin responsiveness in U-937 human promonocytic cells via the downregulation of its own receptor. Cell Biochem Funct 20 (2002) 237-245
    • (2002) Cell Biochem Funct , vol.20 , pp. 237-245
    • Campion, J.1    Maestro, B.2    Molero, S.3    Davila, N.4    Carranza, M.C.5    Calle, C.6
  • 19
    • 0032708131 scopus 로고    scopus 로고
    • Leptin levels are suppressed in primary aldosteronism
    • Torpy D.J. Leptin levels are suppressed in primary aldosteronism. Horm Metab Res 31 (1999) 533-536
    • (1999) Horm Metab Res , vol.31 , pp. 533-536
    • Torpy, D.J.1
  • 20
    • 2442695641 scopus 로고    scopus 로고
    • Aldosterone stimulates gene expression of hepatic gluconeogenic enzymes through the glucocorticoids receptor in a manner independent of protein kinase B cascade
    • Yamashita R., Kikuchi T., Mori Y., Kaburagi Y., and Yasuda K. Aldosterone stimulates gene expression of hepatic gluconeogenic enzymes through the glucocorticoids receptor in a manner independent of protein kinase B cascade. Endocrinol 51 (2004) 243-251
    • (2004) Endocrinol , vol.51 , pp. 243-251
    • Yamashita, R.1    Kikuchi, T.2    Mori, Y.3    Kaburagi, Y.4    Yasuda, K.5
  • 23
    • 33845358123 scopus 로고    scopus 로고
    • Aldosterone as a key mediator of the cardiometaboic syndrome in primary aldosteronism:in observational study
    • Giacchetti G., Ronconi V., Turchi F., Agostinelli L., Mantero F., Rilli S., and Boscaro M. Aldosterone as a key mediator of the cardiometaboic syndrome in primary aldosteronism:in observational study. J Hypertens 25 (2007) 177-186
    • (2007) J Hypertens , vol.25 , pp. 177-186
    • Giacchetti, G.1    Ronconi, V.2    Turchi, F.3    Agostinelli, L.4    Mantero, F.5    Rilli, S.6    Boscaro, M.7
  • 25
    • 28444497837 scopus 로고    scopus 로고
    • High-fat diet feeding impairs both the expression and activity of AMPKa in rats skeletal muscle
    • Liu Y., Wan Q., Guan O., Gao L., and Zhao J. High-fat diet feeding impairs both the expression and activity of AMPKa in rats skeletal muscle. Biochem Biophy Res Commun, 339 (2006) 701-707
    • (2006) Biochem Biophy Res Commun , vol.339 , pp. 701-707
    • Liu, Y.1    Wan, Q.2    Guan, O.3    Gao, L.4    Zhao, J.5
  • 26
    • 33646472627 scopus 로고    scopus 로고
    • The diurnal periodicity of hexose transporter mRNA and protein levels in the rat jejunum: role of vagal innervation
    • Houghton S.G., Zarroug A.E., Duenes J.A., Fernandez-Zapico M.E., and Sarr M.G. The diurnal periodicity of hexose transporter mRNA and protein levels in the rat jejunum: role of vagal innervation. Surgery 139 (2006) 542-549
    • (2006) Surgery , vol.139 , pp. 542-549
    • Houghton, S.G.1    Zarroug, A.E.2    Duenes, J.A.3    Fernandez-Zapico, M.E.4    Sarr, M.G.5
  • 28
    • 0029925423 scopus 로고    scopus 로고
    • A new procedure for the isolation of plasma membrane, T-tubules and internal membranes from skeletal muscles
    • Dombrowski L., Roy D., Mareotte B., and Marette A. A new procedure for the isolation of plasma membrane, T-tubules and internal membranes from skeletal muscles. A J Physiol 270 (1996) E667-E676
    • (1996) A J Physiol , vol.270
    • Dombrowski, L.1    Roy, D.2    Mareotte, B.3    Marette, A.4
  • 30
    • 0014949207 scopus 로고
    • Cleavage of structural protein during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural protein during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 31
    • 11844272529 scopus 로고
    • Determination of glycogen with anthrone reagent
    • Hassid W.Z., and Abraham S. Determination of glycogen with anthrone reagent. Methods Enzymol 3 (1957) 34-37
    • (1957) Methods Enzymol , vol.3 , pp. 34-37
    • Hassid, W.Z.1    Abraham, S.2
  • 32
    • 84970968747 scopus 로고    scopus 로고
    • Biology of skeletal muscle
    • Kahn C.R., Weir G.C., King G.L., Jacobson A.M., Moses A.C., and Smith R.J. (Eds), A Wolters Klunwer Company, Indian edition by BI publication, India
    • Jozsi A.C., and Goodyear L.J. Biology of skeletal muscle. In: Kahn C.R., Weir G.C., King G.L., Jacobson A.M., Moses A.C., and Smith R.J. (Eds). Joslin's diabetes Mellitus (2005), A Wolters Klunwer Company, Indian edition by BI publication, India 227-241
    • (2005) Joslin's diabetes Mellitus , pp. 227-241
    • Jozsi, A.C.1    Goodyear, L.J.2
  • 33
    • 0019405711 scopus 로고
    • Insulin binding and glucose uptake differences in rodent skeletal muscles
    • Bonen A., Tan M.H., and Watson-Wright W.M. Insulin binding and glucose uptake differences in rodent skeletal muscles. Diabetes 30 (1981) 702-704
    • (1981) Diabetes , vol.30 , pp. 702-704
    • Bonen, A.1    Tan, M.H.2    Watson-Wright, W.M.3
  • 34
    • 0001859615 scopus 로고
    • Muscle fiber recruitment patterns and their metabolic correlates
    • Horton E.S., and Terjung R.L. (Eds), Macmillan, Newyork
    • Armstrong R.B. Muscle fiber recruitment patterns and their metabolic correlates. In: Horton E.S., and Terjung R.L. (Eds). Exercise, nutrition and energy metabolism (1988), Macmillan, Newyork 9-26
    • (1988) Exercise, nutrition and energy metabolism , pp. 9-26
    • Armstrong, R.B.1
  • 36
    • 0021343295 scopus 로고
    • Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
    • Holloszy J.O., and Coyle E.F. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J Appl Physiol 56 (1984) 831-838
    • (1984) J Appl Physiol , vol.56 , pp. 831-838
    • Holloszy, J.O.1    Coyle, E.F.2
  • 38
    • 0025779636 scopus 로고
    • Hepatic fuel metabolism during muscular work:role and regulation
    • Wasserman D.H., and Cherrington A.D. Hepatic fuel metabolism during muscular work:role and regulation. Am J Physiol 260 (1991) E811-E824
    • (1991) Am J Physiol , vol.260
    • Wasserman, D.H.1    Cherrington, A.D.2
  • 39
    • 0015899368 scopus 로고
    • A study of the androgen receptors in a variety of androgen-sensitive tissues
    • Mainwaring W.I.P., and Mangan F.R. A study of the androgen receptors in a variety of androgen-sensitive tissues. J Endocrinol 10 (1973) 121-139
    • (1973) J Endocrinol , vol.10 , pp. 121-139
    • Mainwaring, W.I.P.1    Mangan, F.R.2
  • 40
    • 1842471195 scopus 로고    scopus 로고
    • An overview of the endocrinology of skeletal muscle
    • Sheffield-Moore M., and Urban R.J. An overview of the endocrinology of skeletal muscle. Trends Endocrinol Metabol 15 (2004) 110-115
    • (2004) Trends Endocrinol Metabol , vol.15 , pp. 110-115
    • Sheffield-Moore, M.1    Urban, R.J.2
  • 42
    • 0038012932 scopus 로고    scopus 로고
    • The effect of aldosterone on glucose metabolism
    • Corry D.B., and Tuck M.L. The effect of aldosterone on glucose metabolism. Curr Hypertens Rep 5 (2003) 106-109
    • (2003) Curr Hypertens Rep , vol.5 , pp. 106-109
    • Corry, D.B.1    Tuck, M.L.2
  • 43
    • 0035856943 scopus 로고    scopus 로고
    • Diabetes mellitus and genetically programmed defects in beta-cell function
    • Bell G.I., and Polonsky K.S. Diabetes mellitus and genetically programmed defects in beta-cell function. Nature 414 (2001) 788-791
    • (2001) Nature , vol.414 , pp. 788-791
    • Bell, G.I.1    Polonsky, K.S.2
  • 44
    • 0034856812 scopus 로고    scopus 로고
    • Intracellular mechanism underlying increases in glucose uptake in response to insulin or exercise in skeletal muscle
    • Ryder J.W., Chibalin A.V., and Zierath J.R. Intracellular mechanism underlying increases in glucose uptake in response to insulin or exercise in skeletal muscle. Acta Physiol Scand 171 (2001) 249-257
    • (2001) Acta Physiol Scand , vol.171 , pp. 249-257
    • Ryder, J.W.1    Chibalin, A.V.2    Zierath, J.R.3
  • 45
    • 0035106864 scopus 로고    scopus 로고
    • GLUT 4 at the cross roads between membrane trafficking and signal transduction
    • Simpson F., Whitehead J.P., and James D.E. GLUT 4 at the cross roads between membrane trafficking and signal transduction. Traffic 2 (2001) 2-11
    • (2001) Traffic , vol.2 , pp. 2-11
    • Simpson, F.1    Whitehead, J.P.2    James, D.E.3
  • 48
    • 84970993224 scopus 로고    scopus 로고
    • Regulation of hepatic glucose metabolism
    • Kahn C.R., King G.L., Moses A.C., Weir G.C., Jacobson A.M., and Smith R.J. (Eds) Boston
    • Granner DK Scott D.K. Regulation of hepatic glucose metabolism. In: Kahn C.R., King G.L., Moses A.C., Weir G.C., Jacobson A.M., and Smith R.J. (Eds). Joslin's diabetes mellitus. 14th edition (2005) 243-263 Boston
    • (2005) Joslin's diabetes mellitus. 14th edition , pp. 243-263
    • Granner DK Scott, D.K.1
  • 49
    • 0032797852 scopus 로고    scopus 로고
    • Regulation of glucose production by the liver
    • Nordlie R.C., Foster J.D., and Lange A.J. Regulation of glucose production by the liver. Annu Rev Nutr 19 (1999) 379-406
    • (1999) Annu Rev Nutr , vol.19 , pp. 379-406
    • Nordlie, R.C.1    Foster, J.D.2    Lange, A.J.3
  • 50
    • 0026454282 scopus 로고
    • Evidence that GLUT2 mRNA and protein concentration are decreased by hyperinsulinemia and increased by hyperglycemia in the liver of diabetic rats
    • Burcelin R., Eddouk M., Kande J., Assan R., and Girad J. Evidence that GLUT2 mRNA and protein concentration are decreased by hyperinsulinemia and increased by hyperglycemia in the liver of diabetic rats. Biochem J 288 (1992) 675-679
    • (1992) Biochem J , vol.288 , pp. 675-679
    • Burcelin, R.1    Eddouk, M.2    Kande, J.3    Assan, R.4    Girad, J.5
  • 51
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans R.M. The steroid and thyroid hormone receptor superfamily. Science 240 (1988) 889-895
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 52
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato M. Gene regulation by steroid hormones. Cell 56 (1989) 335-344
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 53
    • 0028876441 scopus 로고
    • Regulation of glucose transporters in cultured rat adipocytes: synergistic effect of insulin and dexamethasone on GLUT4 gene expression through promoter activation
    • Hajduch E., Hainault I., Meunier C., Jardel C., Hainque B., Guerre-Millo M., and Lavau M. Regulation of glucose transporters in cultured rat adipocytes: synergistic effect of insulin and dexamethasone on GLUT4 gene expression through promoter activation. Endocrinology 136 (1995) 4782-4789
    • (1995) Endocrinology , vol.136 , pp. 4782-4789
    • Hajduch, E.1    Hainault, I.2    Meunier, C.3    Jardel, C.4    Hainque, B.5    Guerre-Millo, M.6    Lavau, M.7
  • 54
    • 0025188132 scopus 로고
    • Transcriptional between c-jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction
    • Yang-Yen H.F., Chambard J.C., Sun Y.L., Smeal T., Schmidt T.J., Drouin J., and Karin M. Transcriptional between c-jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62 (1990) 1205-1215
    • (1990) Cell , vol.62 , pp. 1205-1215
    • Yang-Yen, H.F.1    Chambard, J.C.2    Sun, Y.L.3    Smeal, T.4    Schmidt, T.J.5    Drouin, J.6    Karin, M.7
  • 55
    • 0026595349 scopus 로고
    • Insulin induces translocation of the GLUT4 from a unique intracellular organelle to the transverse tubules in rat skeletal muscle
    • Marette A., Burdett E., Douen A., Vranic M., and Klip A. Insulin induces translocation of the GLUT4 from a unique intracellular organelle to the transverse tubules in rat skeletal muscle. Diabetes 41 (1992) 1562-1569
    • (1992) Diabetes , vol.41 , pp. 1562-1569
    • Marette, A.1    Burdett, E.2    Douen, A.3    Vranic, M.4    Klip, A.5
  • 56
    • 0029562270 scopus 로고
    • The T-tubule is a cell-surface target for insulin-regulated recycling of membrane proteins in skeletal muscle
    • Munoz P., Rosenblatt M., Testar X., Palacin M., Thoidis G., Pilch P.R., and Zorzano A. The T-tubule is a cell-surface target for insulin-regulated recycling of membrane proteins in skeletal muscle. Biochem J 312 (1995) 393-400
    • (1995) Biochem J , vol.312 , pp. 393-400
    • Munoz, P.1    Rosenblatt, M.2    Testar, X.3    Palacin, M.4    Thoidis, G.5    Pilch, P.R.6    Zorzano, A.7
  • 57
    • 0032555928 scopus 로고    scopus 로고
    • Analysis of GLUT4 distribution in whole skeletal muscle fibers:identification of distinct storage compartments that are reduced by insulin and muscle contractions
    • Ploug T., Van Deurs B., Ai H., Cushman S.W., and Ralston E. Analysis of GLUT4 distribution in whole skeletal muscle fibers:identification of distinct storage compartments that are reduced by insulin and muscle contractions. J Cell Biol 142 (1998) 1429-1446
    • (1998) J Cell Biol , vol.142 , pp. 1429-1446
    • Ploug, T.1    Van Deurs, B.2    Ai, H.3    Cushman, S.W.4    Ralston, E.5
  • 59
    • 0031057526 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation
    • Bjornholm M., Kawano Y., Lehtihet M., and Zierath J.R. Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetes 46 (1997) 524-527
    • (1997) Diabetes , vol.46 , pp. 524-527
    • Bjornholm, M.1    Kawano, Y.2    Lehtihet, M.3    Zierath, J.R.4
  • 60
  • 62
    • 0031688546 scopus 로고    scopus 로고
    • In vivo tissue specific modulation of rat insulin receptor gene expression in an experimental model of mineralocorticoid excess
    • Campion J., Lahera V., Cachofeiro V., Maestro B., Davila N., Carranza M.C., and Calle C. In vivo tissue specific modulation of rat insulin receptor gene expression in an experimental model of mineralocorticoid excess. Mol Cell Biochem 185 (1998) 177-182
    • (1998) Mol Cell Biochem , vol.185 , pp. 177-182
    • Campion, J.1    Lahera, V.2    Cachofeiro, V.3    Maestro, B.4    Davila, N.5    Carranza, M.C.6    Calle, C.7
  • 63
    • 0034101846 scopus 로고    scopus 로고
    • Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment
    • Sindelka G., Widisky J., Haas T., Prazny M., Hilgertova J., and Skrha J. Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment. Exp Clin Endocrinol Diab 108 (2000) 21-25
    • (2000) Exp Clin Endocrinol Diab , vol.108 , pp. 21-25
    • Sindelka, G.1    Widisky, J.2    Haas, T.3    Prazny, M.4    Hilgertova, J.5    Skrha, J.6
  • 64
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signaling and the regulation of glucose and lipid metabolism
    • Saltiel A.R., and Khan C.R. Insulin signaling and the regulation of glucose and lipid metabolism. Nature 41 (2001) 799-806
    • (2001) Nature , vol.41 , pp. 799-806
    • Saltiel, A.R.1    Khan, C.R.2
  • 66
    • 0032542244 scopus 로고    scopus 로고
    • Primary aldosteronism
    • Ganguly A. Primary aldosteronism. N Engl J Med 339 (1998) 1828-1834
    • (1998) N Engl J Med , vol.339 , pp. 1828-1834
    • Ganguly, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.