The mechanism of the actions of oxaliplatin on ion currents and action potentials in differentiated NG108-15 neuronal cells

NeuroToxicology

Volumn 30, Issue 4, 2009, Pages 677-685

  Wu, Sheng Nan ^a   Chen, Bing Shuo ^a,b   Wu, Yung Han ^a   Peng, Hsung ^a   Chen, Li Tzong ^c  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Action potential; Ca2+ current; Delayed rectifier K+ current; Na+ current; Neuroblastoma cells; Oxaliplatin; Persistent Na+ current

Indexed keywords

CALCIUM CHANNEL L TYPE; DELAYED RECTIFIER POTASSIUM CHANNEL; OXALIPLATIN; RANOLAZINE; RILUZOLE; SCN5A PROTEIN; SODIUM CHANNEL; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; ION CURRENT; NERVE CELL MEMBRANE POTENTIAL; NEUROTOXICITY; NONHUMAN; PERIPHERAL NEUROPATHY; POTASSIUM CURRENT; PRIORITY JOURNAL; SODIUM CURRENT;

ACTION POTENTIALS; ANIMALS; ANTINEOPLASTIC AGENTS; BUCLADESINE; CELL LINE; CYCLOPROPANES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HUMANS; HYDROCARBONS, FLUORINATED; ION CHANNEL GATING; LINEAR MODELS; MEMBRANE POTENTIALS; ORGANOPLATINUM COMPOUNDS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRAETHYLAMMONIUM; TETRODOTOXIN; TRANSFECTION;

EID: 67651001970     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2009.04.010     Document Type: Article

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