Olfactory dysfunction is associated with subjective memory complaints in community-dwelling elderly individuals

Journal of Alzheimer's Disease

Volumn 17, Issue 1, 2009, Pages 135-142

  Sohrabi, Hamid R ^a,b   Bates, Kristyn A ^a,b,c   Rodrigues, Mark ^a,b,c   Taddei, Kevin ^a,b,c   Laws, Simon M ^c,d   Lautenschlager, Nicola T ^a,e,f   Dhaliwal, Satvinder S ^g   Johnston, Amy N B ^h   MacKay Sim, Alan ^h   Gandy, Samuel ⁱ   Foster, Jonathan K ^b,c   Martins, Ralph N ^a,b,c  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b HOLLYWOOD PRIVATE HOSPITAL   (Australia)

^c EDITH COWAN UNIVERSITY   (Australia)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^f UNIVERSITY OF MELBOURNE   (Australia)

^g CURTIN UNIVERSITY   (Australia)

^h GRIFFITH UNIVERSITY   (Australia)

ⁱ MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Cognitive decline; Depression symptoms; Olfactory dysfunction; Smell identification; Sniffin' Sticks; Subjective memory complaints

Indexed keywords

BIOLOGICAL MARKER;

ADULT; AGED; AGING; ALZHEIMER DISEASE; ARTICLE; COGNITION; COMMUNITY LIVING; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPRESSION; DIAGNOSTIC TEST; FEMALE; GERIATRIC DEPRESSION SCALE; HUMAN; HUMAN EXPERIMENT; MALE; MEMORY DISORDER; NORMAL HUMAN; OLFACTORY DISCRIMINATION; PRIORITY JOURNAL; QUESTIONNAIRE; RATING SCALE; RISK FACTOR; SCORING SYSTEM; SMELLING DISORDER; SNIFFIN STICKS TEST; SUBJECTIVE MEMORY COMPLAINT;

EID: 67650898564     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2009-1020     Document Type: Article

References (41)

1. Murphy C, Bacon AW, Bondi MW, Salmon DP (1998) Apolipoprotein E status is associated with odor identification deficits in nondemented older persons. AnnN Y Acad Sci 855, 744-750.
2. Graves AB, Bowen JD, Rajaram L, McCormick WC, McCurry SM, Schellenberg GD, Larson EB (1999) Impaired olfaction as a marker for cognitive decline: interaction with apolipoprotein E epsilon4 status. Neurology 53, 1480-1487.
3. Doty RL, Perl DP, Steele JC, Chen KM, Pierce JD, Jr., Reyes P, Kurland LT (1991) Olfactory dysfunction in three neurode- generative diseases. Geriatrics 46 Suppl 1, 47-51.
4. Nordin S, Murphy C (1998) Odor memory in normal aging and Alzheimer's disease. Ann N Y Acad Sci 855, 686-693.
5. Devanand DP, Michaels-Marston KS, Liu X, Pelton GH, Padil- la M, Marder K, Bell K, Stern Y, Mayeux R (2000) Olfactory deficits in patients with mild cognitive impairment predict Alzheimer's disease at follow-up. Am J Psychiatry 157, 1399-1405.
6. Wilson RS, Schneider JA, Arnold SE, Tang Y, Boyle PA, Bennett DA (2007) Olfactory identification and incidence of mild cognitive impairment in older age. Arch Gen Psychiatry 64, 802-808.
7. Treves IA, Verchovsky R, Klimovitzky S, Korczyn AD (2005) Incidence of dementia in patients with subjective memory complaints. Int Psychogeriatr 17, 265-273.
8. Jonker C, Geerlings MI, Schmand B (2000) Are memory complaints predictive for dementia? A review of clinical and population-based studies. Int J Geriatr Psychiatry 15, 983-991.
9. Ponds RWHM, Commissaris KJAM, Jolles J (1997) Prevalence and covariates of subjective forgetfulness in a normal population in the Netherlands. Int J Aging Hum Dev 45, 207-221.
10. Schmand B, Jonker C, Hooijer C, Lindeboom J(1996) Subjective memory complaints may announce dementia. Neurology 46, 121-125.
11. Jorm AF, Butterworth P, Anstey KJ, Christensen H, Easteal S, Maller J, Mather KA, Turakulov RI, Wen W, Sachdev P (2004) Memory complaints in a community sample aged 60-64 years: associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities. Psychol Med 34, 1495-1506.
12. Comijs HC, Deeg DJ, Dik MG, Twisk JW, Jonker C (2002) Memory complaints; the association with psycho-affective and health problems and the role of personality characteristics. A 6-year follow-up study. J Affect Disord 72, 157-165.
13. Levy-Cushman J, Abeles N (1998) Memory complaints in the able elderly Clin Gerontol 19, 3-24.
14. Pearman A, Storandt M (2004) Predictors ofsubjective memory in older adults. J Gerontol B-Psychol 59, 4-6.
15. Niederehe G (1998) The significance of memory complaints in later life: methodological and theoretical considerations In Handbook of aging and mental health: an integrative approach, Lomranz J, ed. Plenum Press, New York, pp. 417-434.
16. Zandi T (2004) Relationship between subjective memory complaints, objective memory performance, and depression among older adults. Am J Alzheimers Dis Other Demen 19, 353-360.
17. Hummel T, Sekinger B, Wolf SR, Pauli E, Kobal G (1997) 'Sniffin' sticks': olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold. Chem Senses 22, 39-52.
18. Gilewski MJ, Zelinski EM, Schaie KW (1990) The Memory Functioning Questionnaire for assessment of memory complaints in adulthood and old age. Psychol Aging 5, 482-490.
19. Zelinski EM, Gilewski MJ, Anthony-Bergstone CR (1990) Memory Functioning Questionnaire: concurrent validity with memory performance and self-reported memory failures. Psychol Aging 5, 388-399.
20. Roth M, Huppert FA, Mountjoy CQ, Tym E (1998) CAMDEXR, Cambridge University Press., Cambridge.
21. Schofield PW, Jacobs D, Marder K, Sano M, Stern Y (1997) The validity of new memory complaints in the elderly. Arch Neurol 54, 756-759.
22. Geerlings MI, Jonker C, Bouter LM, Ader HJ, Schmand B (1999) Association between memory complaints and incident Alzheimer's disease in elderly people with normal baseline cognition. Am J Psychiatry 156, 531-537.
23. Hummel T, Kobal G, Gudziol H, Mackay-Sim A (2007) Normative data for the "Sniffin' Sticks" including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group ofmore than 3,000 subjects. Eur Arch Otorhinolaryngol 264, 237-243.
24. Mackay-Sim A, Grant L, Owen C, Chant D, Silburn P (2004) Australian norms for a quantitative olfactory function test. J Clin Neurosci 11, 874-879.
25. Beardsall L(1998) Development ofthe Cambridge Contextual Reading Test for improving the estimation of premorbid verbal intelligence in older persons with dementia. Br JClin Psychol 37 (Pt 2), 229-240.
26. Folstein MF, Folstein SE, McHugh PR (1975) "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. JPsychiatr Res 12, 189-198.
27. Tombaugh TN, Mclntyre NJ (1992) The mini-mental state examination: a comprehensive review. J Am Geriatr Soc 40, 922-935.
28. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO (1983) Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res 17, 37-49.
29. Pallant J (2001) SPSS survival manual, Allen &Unwin, Crows Nest, Australia.
30. Tabachnick BG, Fidell LS (2001) Using multivariate statistics, Allyn & Bacon, Boston, USA.
31. Crook TH, 3rd, Feher EP, Larrabee GJ (1992) Assessment of memory complaint in age-associated memory impairment: the MAC-Q. Int Psychogeriatr 4, 165-176.
32. Minett TS, Da Silva RV, Ortiz KZ, Bertolucci PH (2007) Subjective memory complaints in an elderly sample: a cross- sectional study. Int JGeriatr Psychiatry23, 49-54.
33. Purser JL, Fillenbaum GG, Wallace RB (2006) Memory complaint is not necessary for diagnosis ofmild cognitive impairment and does not predict 10-year trajectories of functional disability, word recall, or short portable mental status questionnaire limitations. JAm Geriatr Soc 54, 335-338.
34. Reid LM, Maclullich AM (2006) Subjective memory complaints and cognitive impairment in older people. Dement Geriatr Cogn Disord 22, 471-485.
35. Finkel D, Pedersen NL, Larsson M (2001) Olfactory functioning and cognitive abilities: a twin study. J Gerontol B Psychol Sci Soc Sci 56, P226-233
36. Kovacs T (2004) Mechanisms of olfactory dysfunction in aging and neurodegenerative disorders. Ageing Res Rev 3, 215-232.
37. Steiner JE, Lidar-Lifschitz D, Perl E (1993) Taste and odor: Reactivity in depressive disorders, a multidisciplinary approach. Percept Mot Skills 77, 1331-1346.
38. Lombion-Pouthier S, Vandel P, Nezelof S, Haffen E, Millot JL (2006) Odor perception in patients with mood disorders. J Affect Disord 90, 187-191.
39. McCaffrey RJ, Duff K, Solomon GS (2000) Olfactory dysfunction discriminates probable Alzheimer's dementia from major depression: a cross-validation and extension. J Neu- ropsychiatry Clin Neurosci 12, 29-33.
40. Warner M, Peabody C, Csernansky J (1990) Olfactory functioning in schizophrenia and depression. Biol Psychiatry 27, 457-467.
41. Foster J, Sohrabi H, Verdile G, Martins R (2008) Research criteria for the diagnosis of Alzheimer's disease: genetic risk factors, blood biomarkers and olfactory dysfunction. Int Psychogeriatr 20, 853-855.