메뉴 건너뛰기




Volumn 17, Issue 1, 2009, Pages 203-211

Delusion symptoms and response to antipsychotic treatment are associated with the 5-HT2A receptor polymorphism (102T/C) in alzheimer's disease: A 3-year follow-up longitudinal study

Author keywords

5 HT2A receptor; Alzheimer's disease; Antipsychotic drugs; Delusions; Hallucinations

Indexed keywords

OLANZAPINE; QUETIAPINE; RISPERIDONE; SEROTONIN 2A RECEPTOR;

EID: 67650888591     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2009-1031     Document Type: Article
Times cited : (29)

References (35)
  • 1
    • 38449103010 scopus 로고    scopus 로고
    • Agitation and psychosis in dementia
    • Ballard C (2007) Agitation and psychosis in dementia. Am J Geriatr Psychiatry 15, 913-917.
    • (2007) Am J Geriatr Psychiatry , vol.15 , pp. 913-917
    • Ballard, C.1
  • 2
    • 33845889239 scopus 로고    scopus 로고
    • Psychosis-related disturbances. Psychosis, agitation, and disinhibition in Alzheimer's disease: Definitions and treatment options
    • Lesser JM, Hughes S (2006) Psychosis-related disturbances. Psychosis, agitation, and disinhibition in Alzheimer's disease: definitions and treatment options. Geriatrics 61, 14-20.
    • (2006) Geriatrics , vol.61 , pp. 14-20
    • Lesser, J.M.1    Hughes, S.2
  • 3
    • 33645777490 scopus 로고    scopus 로고
    • Prediction of psychosis onset in Alzheimer disease: The role of cognitive impairment, depressive symptoms, and further evidence for psychosis subtypes
    • Wilkosz PA, Miyahara S, Lopez OL, Dekosky ST, Sweet RA (2006) Prediction of psychosis onset in Alzheimer disease: The role of cognitive impairment, depressive symptoms, and further evidence for psychosis subtypes. Am J Geriatr Psychiatry 14, 352-360.
    • (2006) Am J Geriatr Psychiatry , vol.14 , pp. 352-360
    • Wilkosz, P.A.1    Miyahara, S.2    Lopez, O.L.3    Dekosky, S.T.4    Sweet, R.A.5
  • 4
    • 0030882246 scopus 로고    scopus 로고
    • The impact of the symptoms of dementia on caregivers
    • Donaldson C, Tarrier N, Burns A (1997) The impact of the symptoms of dementia on caregivers. Br J Psychiatry 170, 62-68.
    • (1997) Br J Psychiatry , vol.170 , pp. 62-68
    • Donaldson, C.1    Tarrier, N.2    Burns, A.3
  • 5
    • 0033541140 scopus 로고    scopus 로고
    • Nursing home placement is related to dementia progression: Experience from a clinical trial
    • Knopman DS, Berg JD, Thomas R, Grundman M, Thal LJ, Sano M (1999) Nursing home placement is related to dementia progression: experience from a clinical trial. Neurology 52, 714-718.
    • (1999) Neurology , vol.52 , pp. 714-718
    • Knopman, D.S.1    Berg, J.D.2    Thomas, R.3    Grundman, M.4    Thal, L.J.5    Sano, M.6
  • 6
    • 33645527991 scopus 로고    scopus 로고
    • The effectiveness of atypical an- tipsychotics for the treatment of aggression and psychosis in Alzheimer's disease
    • CD003476
    • Ballard C, Waite J (2006) The effectiveness of atypical an- tipsychotics for the treatment of aggression and psychosis in Alzheimer's disease. Cochrane Database Syst Rev 1, CD003476.
    • (2006) Cochrane Database Syst Rev , vol.1
    • Ballard, C.1    Waite, J.2
  • 7
    • 0028469704 scopus 로고
    • Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease
    • Forstl H, Burns A, Levy R, Cairns N (1994) Neuropathological correlates of psychotic phenomena in confirmed Alzheimer's disease. Br J Psychiatry 165, 53-59.
    • (1994) Br J Psychiatry , vol.165 , pp. 53-59
    • Forstl, H.1    Burns, A.2    Levy, R.3    Cairns, N.4
  • 9
    • 0032145210 scopus 로고    scopus 로고
    • The spectrum of behaviors influenced by serotonin
    • Lucki I (1998) The spectrum of behaviors influenced by serotonin. Biol Psychiatry 44, 151-162.
    • (1998) Biol Psychiatry , vol.44 , pp. 151-162
    • Lucki, I.1
  • 10
    • 9644278029 scopus 로고    scopus 로고
    • Implications for atypical antipsychotics in the treatment of schizophrenia: Neurocognition effects and a neuroprotective hypothesis
    • Jann MW. (2004) Implications for atypical antipsychotics in the treatment of schizophrenia: neurocognition effects and a neuroprotective hypothesis. Pharmacotherapy 24, 1759-1783.
    • (2004) Pharmacotherapy , vol.24 , pp. 1759-1783
    • Jann, M.W.1
  • 11
    • 0031596301 scopus 로고    scopus 로고
    • Alzheimer's disease
    • 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset
    • Holmes C, Arranz MJ, Powell JF, Collier DA, Lovestone S (1998) 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease. Hum Mol Genet 7, 1507-1509.
    • (1998) Hum Mol Genet , vol.7 , pp. 1507-1509
    • Holmes, C.1    Arranz, M.J.2    Powell, J.F.3    Collier, D.A.4    Lovestone, S.5
  • 13
    • 1042289665 scopus 로고    scopus 로고
    • Serotoninergic polymorphisms (5-HTTLPR and 5-HT2A): Association studies with psychosis in Alzheimer disease
    • Winter
    • Rocchi A, Micheli D, Ceravolo R, Manca ML, Tognoni G, Siciliano G, Murri L (2003) Serotoninergic polymorphisms (5-HTTLPR and 5-HT2A): association studies with psychosis in Alzheimer disease. Genet Test Winter 7, 309-314.
    • (2003) Genet Test , vol.7 , pp. 309-314
    • Rocchi, A.1    Micheli, D.2    Ceravolo, R.3    Manca, M.L.4    Tognoni, G.5    Siciliano, G.6    Murri, L.7
  • 14
    • 3042855136 scopus 로고    scopus 로고
    • 5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease
    • Lam LC, Tang NL, Ma SL, Zhang W, Chiu HF (2004) 5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease, Int J Geriatric Psychiatry 19, 523-526.
    • (2004) Int J Geriatric Psychiatry , vol.19 , pp. 523-526
    • Lam, L.C.1    Tang, N.L.2    Ma, S.L.3    Zhang, W.4    Chiu, H.F.5
  • 16
    • 4043174258 scopus 로고    scopus 로고
    • Aug;Association of the serotonin transporter and receptor gene polymorphisms in neuropsychi- atric symptoms in Alzheimer disease
    • Assal F, Alarcon M, Solomon EC, Masterman D, Geschwind DH, Cummings JL (2004) Aug;Association of the serotonin transporter and receptor gene polymorphisms in neuropsychi- atric symptoms in Alzheimer disease. Arch Neurol 61, 1249-1253.
    • (2004) Arch Neurol , vol.61 , pp. 1249-1253
    • Assal, F.1    Alarcon, M.2    Solomon, E.C.3    Masterman, D.4    Geschwind, D.H.5    Cummings, J.L.6
  • 18
  • 20
    • 0036713871 scopus 로고    scopus 로고
    • Association of risperidone treatment response with a polymorphism in the 5-HT(2A) receptor gene
    • Lane HY, Chang YC, Chiu CC, Chen ML, Hsieh MH, Chang WH (2002) Association of risperidone treatment response with a polymorphism in the 5-HT(2A) receptor gene. Am JPsychi- atry 159, 1593-1595.
    • (2002) Am JPsychi- atry , vol.159 , pp. 1593-1595
    • Lane, H.Y.1    Chang, Y.C.2    Chiu, C.C.3    Chen, M.L.4    Hsieh, M.H.5    Chang, W.H.6
  • 21
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 22
    • 0016823810 scopus 로고
    • Mini Mental State: A practical method for grading the cognitive state of patients for clinician
    • Folstein MF, Folstein SE, McHugh PR (1975) Mini Mental State: a practical method for grading the cognitive state of patients for clinician. J Psychiatric Res; 12, 189-198.
    • (1975) J Psychiatric Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 23
    • 3042857903 scopus 로고    scopus 로고
    • Alzheimer's disease
    • Cummings JL (2004) Alzheimer's disease. N Engl J Med 351, 56-67.
    • (2004) N Engl J Med , vol.351 , pp. 56-67
    • Cummings, J.L.1
  • 24
    • 0030958347 scopus 로고    scopus 로고
    • The Neuropsychiatric Inventory: Assessing psychopathology in dementia patients
    • Cummings JL (1997) The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. Neurology 48, S10-S16.
    • (1997) Neurology , vol.48
    • Cummings, J.L.1
  • 25
    • 0014579432 scopus 로고
    • Assessment of older people: Self-maintaining and instrumental activities of daily living
    • Lawton MP, Brody EM (1969) Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 9, 179-186.
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 27
    • 17844377615 scopus 로고    scopus 로고
    • HTR2A: Association and expression studies in neuropsychiatric genetics
    • Norton N, Owen MJ (2005) HTR2A: association and expression studies in neuropsychiatric genetics. Ann Med 37, 121-129.
    • (2005) Ann Med , vol.37 , pp. 121-129
    • Norton, N.1    Owen, M.J.2
  • 29
    • 0037086178 scopus 로고    scopus 로고
    • Differential expression of the 'C' and 'T' alleles of the 5-HT2A receptor gene in the temporal cortex of normal individuals and schizophrenics
    • Polesskaya OO, Sokolov BP (2002) Differential expression of the 'C' and 'T' alleles of the 5-HT2A receptor gene in the temporal cortex of normal individuals and schizophrenics. J Neurosci Res 67, 812-822.
    • (2002) J Neurosci Res , vol.67 , pp. 812-822
    • Polesskaya, O.O.1    Sokolov, B.P.2
  • 31
    • 0031930011 scopus 로고    scopus 로고
    • PET imaging of central 5-HT2A receptors with carbon-11-MDL 100,907
    • Ito H, Nyberg S, Halldin C, Lundkvist C, Farde L (1998) PET imaging of central 5-HT2A receptors with carbon-11-MDL 100,907. J Nucl Med39, 208-214.
    • (1998) J Nucl Med , vol.39 , pp. 208-214
    • Ito, H.1    Nyberg, S.2    Halldin, C.3    Lundkvist, C.4    Farde, L.5
  • 32
    • 0032970989 scopus 로고    scopus 로고
    • A review ofcentral 5HT receptors and their functions
    • Barnes N, Sharp T (1999) A review ofcentral 5HT receptors and their functions, Neuropharmacology 38, 1083-1152.
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.1    Sharp, T.2
  • 33
    • 0028972384 scopus 로고
    • Reassessment of LSD false positives
    • Role of the 5HT2A and 5HT2C receptors in the stimulus effects ofhallucinogenic drugs. II
    • Fiorella D, Rabin R, Winter J (1995) Role of the 5HT2A and 5HT2C receptors in the stimulus effects ofhallucinogenic drugs. II. Reassessment of LSD false positives, Psychophar-macology 121, 357-363.
    • (1995) Psychophar-macology , vol.121 , pp. 357-363
    • Fiorella, D.1    Rabin, R.2    Winter, J.3
  • 34
    • 0028237637 scopus 로고
    • Risperidone: A novel antipsychotic with balanced serotonin- dopamine antagonism, receptor occupancy profile, and phar- macologic activity
    • Leysen JE, Janssen PM, Megens AA, Schotte A (1994) Risperidone: a novel antipsychotic with balanced serotonin- dopamine antagonism, receptor occupancy profile, and phar- macologic activity. J Clin Psychiatry 55, 5-12.
    • (1994) J Clin Psychiatry , vol.55 , pp. 5-12
    • Leysen, J.E.1    Janssen, P.M.2    Megens, A.A.3    Schotte, A.4
  • 35
    • 0033833076 scopus 로고    scopus 로고
    • A PET study of brain 5-HT2 receptors and their correlation with platelet 5-HT2 receptors in healthy humans
    • Yatham LN, Steiner M, Liddle PF, Shiah IS, Lam RW, Zis AP, Coote M (2000) A PET study of brain 5-HT2 receptors and their correlation with platelet 5-HT2 receptors in healthy humans. Psychopharmacology 151, 424-427.
    • (2000) Psychopharmacology , vol.151 , pp. 424-427
    • Yatham, L.N.1    Steiner, M.2    Liddle, P.F.3    Shiah, I.S.4    Lam, R.W.5    Zis, A.P.6    Coote, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.