Defective phagocytosis in Anaplasma phagocytophilum-infected neutrophils

Infection and Immunity

Volumn 73, Issue 2, 2005, Pages 1187-1190

  Garyu, Justin W A ^a   Choi, Kyoung Seong ^a   Grab, Dennis J ^a   Dumler, J Stephen ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYL SULFOXIDE;

ANAPLASMA PHAGOCYTOPHILUM; ARTICLE; ASSAY; BACTERIAL INFECTION; CANDIDA ALBICANS; CELL FUNCTION; CELL STRAIN HL 60; CONTROLLED STUDY; DISEASE EXACERBATION; FLUORESCENCE; FLUORESCENT AGGREGATE PHAGOCYTOSIS ASSAY; HUMAN; HUMAN CELL; INTERNALIZATION; NEUTROPHIL; NONHUMAN; OPPORTUNISTIC INFECTION; PHAGOCYTOSIS; PRIORITY JOURNAL;

ANAPLASMA PHAGOCYTOPHILUM; CANDIDA ALBICANS; HUMANS; NEUTROPHILS; PHAGOCYTOSIS;

EID: 12844260213     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.2.1187-1190.2005     Document Type: Article

References (28)

1. Akkoyunlu, M., S. E. Malawista, J. Anguita, and E. Fikrig. 2001. Exploitation of interleukin-8-induced neutrophil chemotaxis by the agent of human granulocytic ehrlichiosis. Infect. Immun. 69:5577-5588.
2. Bakken, J. S., and J. S. Dumler. 2000. Human granulocytic ehrlichiosis. Clin. Infect. Dis. 31:554-560.
3. phox. J. Immunol. 164:3946-3949.
4. Batungbacal, M. R. 1995. Effect of Cytoecetes phagocytophila on phagocytosis by neutrophils in sheep. Philipp. J. Vet. Med. 32:70-76.
5. Brodie, T. A., P. H. Holmes, and G. M. Urquhart. 1986. Some aspects of tick-borne diseases of British sheep. Vet. Rec. 118:415-418.
6. Carlyon, J. A., W.-T. Chan, J. Galán, D. Roos, and E. Fikrig. 2002. Repression of rac2 mRNA expression by Anaplasma phagocytophila is essential to the inhibition of superoxide production and bacterial proliferation. J. Immunol. 169:7009-7018.
7. Carlyon, J. A., and E. Fikrig. 2003. Invasion and survival strategies of Anaplasma phagocytophilum. Cell. Microbiol. 5:743-754.
8. Choi, K.-S., and J. S. Dumler. 2003. Early induction and late abrogation of respiratory burst in A. phagocytophilum-infected neutrophils. Ann. N. Y. Acad. Sci. 990:488-493.
9. Choi, K.-S., J. Garyu, J. Park, and J. S. Dumler. 2003. Diminished adhesion of Anaplasma phagocytophilum-infected neutrophils to endothelial cells is associated with reduced expression of leukocyte surface selectin. Infect. Immun. 71:4586-4594.
10. Choi, K.-S., D. J. Grab, and J. S. Dumler. 2004. Anaplasma phagocytophilum infection induces protracted neutrophil degranulation. Infect Immun. 72:3680-3683.
11. de la Fuente, J., J. C. Garcia-Garcia, E. F. Blouin, J. T. Saliki, and K. M. Kocan. 2002. Infection of tick cells and bovine erythrocytes with one genotype of the intracellular ehrlichia Anaplasma marginale excludes infection with other genotypes. Clin. Diagn. Lab. Immunol. 9:658-668.
12. de la Fuente, J., E. F. Blouin, and K. M. Kocan. 2003. Infection exclusion of the rickettsial pathogen Anaplasma marginale in the tick vector Dermacentor variabilis. Clin. Diagn. Lab. Immunol. 10:182-184.
13. Foggie, A. 1956. The effect of tick-borne fever on the resistance of lambs to staphylococci. J. Comp. Pathol. 66:278-285.
14. Goodman, J., C. Nelson, B. Vitale, J. E. Madigan, J. S. Dumler, T. Kurtti, and U. Munderloh. 1996. Direct cultivation of the causative agent of human granulocytic ehrlichiosis. N. Engl. J. Med. 334:209-215.
15. Greig, B., K. M. Asanovich, P. J. Armstrong, and J. S. Dumler. 1996. Geographic, clinical, serologic, and molecular evidence of granulocytic ehrlichiosis, a likely zoonotic disease, in Minnesota and Wisconsin dogs. J. Clin. Microbiol. 34:44-48.
16. Klein, M. B., S. Hu, C. C. Cbao, and J. L. Goodman. 2000. The agent of human granulocytic ehrlichiosis induces the production of myelosuppressing chemokines without induction of proinflammatory cytokines. J. Infect. Dis. 182:200-205.
17. Kobayashi, S. D., J. M. Voyich, and F. R. DeLeo. 2003. Regulation of the neutrophil-mediated inflammatory response to infection. Microbes Infect. 5:1337-1344.
18. Lee, W. L., R. E. Harrison, and S. Grinstein. 2003. Phagocytosis by neutrophils. Microbes Infect. 5:1299-1306.
19. Lepidi, H., J. E. Bunnell, M. E. Martin, J. E. Madigan, S. Stuen, and J. S. Dumler. 2000. Comparative pathology, and immunohistology associated with clinical illness after Ehrlichia phagocytophila-group infections. Am. J. Trop. Med. Hyg. 62:29-37.
20. Lilliehöök, I., A. Johannisson, U. Magnusson, A. Egenvall, G. Trowald-Wigb, and L. Hakansson. 1999. Granulocyte function in dogs experimentally infected with a Swedish granulocytic Ehrlichia species. Vet. Immunol. Immunopathol. 67:141-152.
21. Ogden, N. H., Z. Woldehiwet, and C. A. Hart. 1998. Granulocytic ehrlichiosis: an emerging or rediscovered tick-borne disease? J. Med. Microbiol. 47:475-482.
22. Park, J., K.-S. Choi, D. J. Grab, and J. S. Dumler. 2003. Divergent interactions of Ehrlichia chaffeensis- and Anaplasma phagocytophilum-infected leukocytes with endothelial cell barriers. Infect. Immun. 71:6728-6733.
23. Scorpio, D. G., M. Akkoyunlu, E. Fikrig, and J. S. Dumler. 2004. CXCR2 blockade influences Anaplasma phagocytophilum propagation but not histopathology in the mouse model of human granulocytic anaplasmosis. Clin. Diagn. Lab. Immunol. 11:963-968.
24. Walker, D. H., and J. S. Dumler. 1997. Human monocytic and granulocytic ehrlichioses. Discovery and diagnosis of emerging tick-borne infections and the critical role of the pathologist. Arch. Pathol. Lab. Med. 121:785-791.
25. Webster, P., J. W. Ijdo, L. M. Chicoine, and E. Fikrig. 1998. The agent of human granulocytic ehrlichiosis resides in an endosomal compartment. J. Clin. Investig. 101:1932-1941.
26. Whist, S. K., A. K. Storset, and H. J. Larsen. 2002. Functions of neutrophils in sheep experimentally infected with Ehrlichia phagocytophila. Vet. Immunol. Immunopathol. 86:183-193.
27. Woldehiwet, Z. 1987. The effects of tick-borne fever on some functions of polymorphonuclear cells of sheep. J. Comp. Pathol. 97:481-485.
28. Yoshiie, K., H.-Y. Kim, J. Mott, and Y. Rikihisa. 2000. Intracellular infection by the human granulocytic ehrlichiosis agent inhibits human neutrophil apoptosis. Infect. Immun. 68:1125-1133.