메뉴 건너뛰기




Volumn 48, Issue 5, 2009, Pages 526-530

Methotrexate treatment in pediatric crohn disease patients intolerant or resistant to purine analogues

Author keywords

Azathioprine; Children; Crohn disease; Immunomodulators; Methotrexate

Indexed keywords

LIVER ENZYME; MERCAPTOPURINE; METHOTREXATE; STEROID;

EID: 67650882729     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e318196df3e     Document Type: Article
Times cited : (47)

References (20)
  • 1
    • 33947287144 scopus 로고    scopus 로고
    • Thiopurine treatment in inflammatory bowel disease: Clinical pharmacology and implication of pharmacogenetically guided dosing
    • Teml A, Schaeffeler E, Herrlinger KR, et al. Thiopurine treatment in inflammatory bowel disease: clinical pharmacology and implication of pharmacogenetically guided dosing. Clin Pharmacokinet 2007;46:187-208.
    • (2007) Clin Pharmacokinet , vol.46 , pp. 187-208
    • Teml, A.1    Schaeffeler, E.2    Herrlinger, K.R.3
  • 2
    • 33947397636 scopus 로고    scopus 로고
    • Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children
    • Hyames J, Crandall W, Kugathasan S, et al. Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children. Gastroenterology 2007;132:863-73.
    • (2007) Gastroenterology , vol.132 , pp. 863-873
    • Hyames, J.1    Crandall, W.2    Kugathasan, S.3
  • 3
    • 0028899859 scopus 로고
    • Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators
    • Feagan BG, Rochon J, Fedorak RN, et al. Methotrexate for the treatment of Crohn's disease. The North American Crohn's Study Group Investigators. N Engl J Med 1995;332:292-7.
    • (1995) N Engl J Med , vol.332 , pp. 292-297
    • Feagan, B.G.1    Rochon, J.2    Fedorak, R.N.3
  • 4
    • 0034214336 scopus 로고    scopus 로고
    • A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease
    • Feagan BG, Fedorak RN, Irvine EJ, et al. A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. N Engl J Med 2000;342:1627-32.
    • (2000) N Engl J Med , vol.342 , pp. 1627-1632
    • Feagan, B.G.1    Fedorak, R.N.2    Irvine, E.J.3
  • 5
    • 0343081012 scopus 로고    scopus 로고
    • Methotrexate in Crohn's disease: Long-term efficacy and toxicity
    • Lemann M, Zenjari T, Bouhnik Y, et al. Methotrexate in Crohn's disease: long-term efficacy and toxicity. Am J Gastroenterol 2000;95:1730-4.
    • (2000) Am J Gastroenterol , vol.95 , pp. 1730-1734
    • Lemann, M.1    Zenjari, T.2    Bouhnik, Y.3
  • 6
    • 0031596842 scopus 로고    scopus 로고
    • Methotrexate in patients with Crohn's disease after 6-mercaptopurine
    • Mack DR, Young R, Kaufman SS, et al. Methotrexate in patients with Crohn's disease after 6-mercaptopurine. J Pediatr 1998; 132:830-5.
    • (1998) J Pediatr , vol.132 , pp. 830-835
    • Mack, D.R.1    Young, R.2    Kaufman, S.S.3
  • 7
    • 33750519460 scopus 로고    scopus 로고
    • Efficacy of methotraxate in pediatric Crohn's disease: A French multicenter study
    • Uhlen S, Bellbouab R, Narebski K, et al. Efficacy of methotraxate in pediatric Crohn's disease: a French multicenter study. Inflamm Bowel Dis 2006;12:1053-7.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 1053-1057
    • Uhlen, S.1    Bellbouab, R.2    Narebski, K.3
  • 8
    • 36549026839 scopus 로고    scopus 로고
    • Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's disease
    • Turner D, Grossman AB, Rosh J, et al. Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's disease. Am J Gastroenterol 2007;12:2804-12.
    • (2007) Am J Gastroenterol , vol.12 , pp. 2804-2812
    • Turner, D.1    Grossman, A.B.2    Rosh, J.3
  • 9
    • 0019319257 scopus 로고
    • A simple index of Crohn's-disease activity
    • Harvey RF, Bradshaw JM. A simple index of Crohn's-disease activity. Lancet 1980;1:514.
    • (1980) Lancet , vol.1 , pp. 514
    • Harvey, R.F.1    Bradshaw, J.M.2
  • 10
    • 67651005162 scopus 로고    scopus 로고
    • Dixon WJ, Chief ed. BMDP statistical software. Los-Angeles: University of California Press; 1993.
    • Dixon WJ, Chief ed. BMDP statistical software. Los-Angeles: University of California Press; 1993.
  • 11
    • 0031680256 scopus 로고    scopus 로고
    • Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease
    • Kirshner BS. Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease. Gastroenterology 1998;115:813-21.
    • (1998) Gastroenterology , vol.115 , pp. 813-821
    • Kirshner, B.S.1
  • 12
    • 4444319475 scopus 로고    scopus 로고
    • Experience with the use of low-dose methotrexate for inflammatory bowel disease
    • Soon SY, Asari A, Yanez M, et al. Experience with the use of low-dose methotrexate for inflammatory bowel disease. Eur J Gastroenterol Hepatol 2004;16:921-6.
    • (2004) Eur J Gastroenterol Hepatol , vol.16 , pp. 921-926
    • Soon, S.Y.1    Asari, A.2    Yanez, M.3
  • 14
    • 1842425908 scopus 로고    scopus 로고
    • Bioavailability of higher dose methotrexate comparing oral and subcutaneous ad ministration in patients with rheumatoid arthritis
    • Hoekstra M, Haagsma C, Neef C, et al. Bioavailability of higher dose methotrexate comparing oral and subcutaneous ad ministration in patients with rheumatoid arthritis. J Rheumatol 2004; 31:645-8.
    • (2004) J Rheumatol , vol.31 , pp. 645-648
    • Hoekstra, M.1    Haagsma, C.2    Neef, C.3
  • 15
    • 0027744086 scopus 로고
    • A comparison of low dose methotrexate bioavailability: Oral solution, oral tablet, subcutaneous and intramuscular dosing
    • Jundt JW, Browne BA, Fiocci GP, et al. A comparison of low dose methotrexate bioavailability: oral solution, oral tablet, subcutaneous and intramuscular dosing. J Rheumatol 1993; 20:1845-9.
    • (1993) J Rheumatol , vol.20 , pp. 1845-1849
    • Jundt, J.W.1    Browne, B.A.2    Fiocci, G.P.3
  • 16
    • 0023195465 scopus 로고
    • Methotrexate bioavailability after oral and intramuscular administration in children
    • Teresi ME, Crom WR, Choi KE, et al. Methotrexate bioavailability after oral and intramuscular administration in children. J Ped 1987;110:788-92.
    • (1987) J Ped , vol.110 , pp. 788-792
    • Teresi, M.E.1    Crom, W.R.2    Choi, K.E.3
  • 17
    • 0020611303 scopus 로고
    • Pharmacokinetics of oral methotrexate in children
    • Balis FM, Savitch JL, Bleyer WA. Pharmacokinetics of oral methotrexate in children. Cancer Res 1983;43:2342-5.
    • (1983) Cancer Res , vol.43 , pp. 2342-2345
    • Balis, F.M.1    Savitch, J.L.2    Bleyer, W.A.3
  • 18
    • 25444496170 scopus 로고    scopus 로고
    • Low-dose oral methotrexate for maintaining Crohn's disease remission: Where we stand
    • Sun JH, Das KM. Low-dose oral methotrexate for maintaining Crohn's disease remission: where we stand. J Clin Gastro 2005; 39:751-6.
    • (2005) J Clin Gastro , vol.39 , pp. 751-756
    • Sun, J.H.1    Das, K.M.2
  • 19
    • 16844365535 scopus 로고    scopus 로고
    • The bioavailability of oral methotrexate in children with inflammatory bowel disease
    • Stephens MC, Baldassano RN, York A, et al. The bioavailability of oral methotrexate in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2005;40:445-9.
    • (2005) J Pediatr Gastroenterol Nutr , vol.40 , pp. 445-449
    • Stephens, M.C.1    Baldassano, R.N.2    York, A.3
  • 20
    • 1542603602 scopus 로고    scopus 로고
    • Compaison between methotrexate and azathioprine in the treatment of chronic active Crohn's disease: A randomized, investigator-blind study
    • Ardizzone S, Bollani S, Manzionna G, et al. Compaison between methotrexate and azathioprine in the treatment of chronic active Crohn's disease: a randomized, investigator-blind study. Dig Liver Dis 2003;35:619-27.
    • (2003) Dig Liver Dis , vol.35 , pp. 619-627
    • Ardizzone, S.1    Bollani, S.2    Manzionna, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.