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Volumn , Issue , 2007, Pages 407-433

Principles of Mathematical Modeling and in Silico Studies of Integrated Cellular Energetics

Author keywords

Energy transfer networks; Free energy profile; in silico studies; Integrated cellular energetics; Interaction between enzymes; Mathematical modeling; Metabolic feedback regulation; Modeling cellular energetics; Modeling energy metabolism; Molecular system bioenergetics

Indexed keywords


EID: 67650867606     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527621095.ch12     Document Type: Chapter
Times cited : (13)

References (91)
  • 1
    • 0004243729 scopus 로고    scopus 로고
    • Foundations of Systems Biology
    • MIT Press, Boston
    • Kitano, H. (2001) Foundations of Systems Biology. MIT Press, Boston.
    • (2001)
    • Kitano, H.1
  • 3
    • 1542344953 scopus 로고    scopus 로고
    • Continuum biomechanics of soft biological tissues
    • Humphrey, J. D. (2000) Continuum biomechanics of soft biological tissues. Proc. R. Soc. London A 459:3-46.
    • (2000) Proc. R. Soc. London A , vol.459 , pp. 3-46
    • Humphrey, J.D.1
  • 4
    • 2442598065 scopus 로고    scopus 로고
    • The IUPS physiome project: a framework for computational physiology
    • Hunter, P. J. (2004) The IUPS physiome project: a framework for computational physiology. Progr. Biophys. Mol. Biol 85:551-569.
    • (2004) Progr. Biophys. Mol. Biol , vol.85 , pp. 551-569
    • Hunter, P.J.1
  • 6
    • 84900949800 scopus 로고    scopus 로고
    • Mechanisms and modeling of energy transfer between and among intracellular compartments
    • 3 edition, volume 5, Brain Energetics, Dienel G., Gibson G. (Eds.) Springer Science, New York-Boston
    • Saks V.A., Vendelin M., Aliev M.K., Kekelidze T., Engelbrecht J. (2006) Mechanisms and modeling of energy transfer between and among intracellular compartments. In: Handbook of Neurochemistry and Molecular Neurobiology, 3 edition, volume 5, Brain Energetics, Dienel G., Gibson G. (Eds.) Springer Science, New York-Boston, pp. 815-860.
    • (2006) Handbook of Neurochemistry and Molecular Neurobiology , pp. 815-860
    • Saks, V.A.1    Vendelin, M.2    Aliev, M.K.3    Kekelidze, T.4    Engelbrecht, J.5
  • 7
    • 0347303256 scopus 로고    scopus 로고
    • Finite-element modelling: a new tool for the biologist
    • Kolston, P. J. (2000) Finite-element modelling: a new tool for the biologist. Proc. R. Soc. London A 358:611-631.
    • (2000) Proc. R. Soc. London A , vol.358 , pp. 611-631
    • Kolston, P.J.1
  • 8
    • 84889358420 scopus 로고    scopus 로고
    • A framework for soft tissue and musculo-sceletal modelling: clinical uses and future challenges
    • G.A. Holzapfel, K.W. Ogden (Eds.), Springer, Berlin
    • Fernandez, J. W., H. Schmid, P. J. Hunter. (2006) A framework for soft tissue and musculo-sceletal modelling: clinical uses and future challenges. In Mechanics of Biological Tissue, Proc. IUTAM Symp., G.A. Holzapfel, K.W. Ogden (Eds.), pp. 339-354, Springer, Berlin.
    • (2006) Mechanics of Biological Tissue, Proc. IUTAM Symp. , pp. 339-354
    • Fernandez, J.W.1    Schmid, H.2    Hunter, P.J.3
  • 10
  • 11
    • 0028602836 scopus 로고
    • Thermodynamics with internal variables. Part I: general concepts, part ii: Applications
    • Maugin, G. A., W. Muschik. (1994) Thermodynamics with internal variables. Part I: general concepts, part ii: Applications. J. Non-Equilib. Thermodyn. 19:217-249, 250-289.
    • (1994) J. Non-Equilib. Thermodyn. , vol.19
    • Maugin, G.A.1    Muschik, W.2
  • 12
    • 84885739476 scopus 로고    scopus 로고
    • Microstructure described by hierarchical internal variables
    • Engelbrecht, J., M. Vendelin. 2000. Microstructure described by hierarchical internal variables. Rend. Sem. Mat. 58:83-91.
    • (2000) Rend. Sem. Mat. , vol.58 , pp. 83-91
    • Engelbrecht, J.1    Vendelin, M.2
  • 13
    • 0033676319 scopus 로고    scopus 로고
    • Hierarchical internal variables reflecting microstructural properties: application to cardiac muscle contraction
    • Engelbrecht, J., M. Vendelin, G. A. Maugin. (2000) Hierarchical internal variables reflecting microstructural properties: application to cardiac muscle contraction. J. Non-Equilib. Thermodyn. 25:119-130.
    • (2000) J. Non-Equilib. Thermodyn. , vol.25 , pp. 119-130
    • Engelbrecht, J.1    Vendelin, M.2    Maugin, G.A.3
  • 14
    • 0003820984 scopus 로고    scopus 로고
    • The regulation of cellular systems
    • Chapman & Hall, New York
    • Heinrich R., S. Schuster (1996) The regulation of cellular systems. Chapman & Hall, New York.
    • (1996)
    • Heinrich, R.1    Schuster, S.2
  • 15
    • 0003760238 scopus 로고
    • Enzyme kinetics. Behaviour and analysis of rapid equilibrium and steady state enzyme systems
    • Wiley Interscience publication. John Wiley & Sons, New York-London
    • Segel I.H. (1975) Enzyme kinetics. Behaviour and analysis of rapid equilibrium and steady state enzyme systems. Wiley Interscience publication. John Wiley & Sons, New York-London.
    • (1975)
    • Segel, I.H.1
  • 16
    • 0004205267 scopus 로고    scopus 로고
    • Fundamentals of enzyme kinetics
    • Portland Press, London
    • Cornish-Bowden A. (2004) Fundamentals of enzyme kinetics. Portland Press, London.
    • (2004)
    • Cornish-Bowden, A.1
  • 17
    • 84860327254 scopus 로고    scopus 로고
    • Cinétique Enzymatique
    • EDP Sciences, Les Ulis
    • Cornish-Bowden A., Jamin M., Saks V. (2005) Cinétique Enzymatique. EDP Sciences, Les Ulis.
    • (2005)
    • Cornish-Bowden, A.1    Jamin, M.2    Saks, V.3
  • 18
    • 50549155520 scopus 로고
    • The kinetics of enzyme-catalyzed reactions with two or more substrates or products. III. Prediction of initial velocity and inhibition patterns by inspection
    • Cleland W.W. (1963) The kinetics of enzyme-catalyzed reactions with two or more substrates or products. III. Prediction of initial velocity and inhibition patterns by inspection. Biochim Biophys Acta. 67, 188-196.
    • (1963) Biochim Biophys Acta. , vol.67 , pp. 188-196
    • Cleland, W.W.1
  • 19
    • 50549188738 scopus 로고
    • The kinetics of enzyme-catalyzed reactions with two or more substrates or products. II. Inhibition: nomenclature and theory
    • Cleland W.W. (1963) The kinetics of enzyme-catalyzed reactions with two or more substrates or products. II. Inhibition: nomenclature and theory. Biochim Biophys Acta 67, 173-187.
    • (1963) Biochim Biophys Acta , vol.67 , pp. 173-187
    • Cleland, W.W.1
  • 20
    • 50549159930 scopus 로고
    • The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations
    • Cleland W.W. (1963) The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations. Biochim Biophys Acta. 67, 104-137.
    • (1963) Biochim Biophys Acta. , vol.67 , pp. 104-137
    • Cleland, W.W.1
  • 21
    • 0001705279 scopus 로고
    • Théorie générale de l'action de quelques diastases
    • Henri V. (1902) Théorie générale de l'action de quelques diastases. Comp. Rend. Acad. Sci. 135, 916-919.
    • (1902) Comp. Rend. Acad. Sci. , vol.135 , pp. 916-919
    • Henri, V.1
  • 22
    • 0000870544 scopus 로고
    • Die Kinetik der Invertinwirkung
    • Michaelis L., Menten M.L. (1913) Die Kinetik der Invertinwirkung, Biochem. Z. 49, 333-369.
    • (1913) Biochem. Z. , vol.49 , pp. 333-369
    • Michaelis, L.1    Menten, M.L.2
  • 23
    • 0004214524 scopus 로고
    • Enzymes
    • Longmans, Green and Co., London
    • Haldane J.B.S. (1930) Enzymes. Longmans, Green and Co., London.
    • (1930)
    • Haldane, J.B.S.1
  • 24
    • 0000240761 scopus 로고
    • Eine Theorie der photochemischen Reactionsgeschwindigkeiten
    • Bodenstein M. (1913) Eine Theorie der photochemischen Reactionsgeschwindigkeiten. Z. Phys. Chem. 85, 329-397.
    • (1913) Z. Phys. Chem. , vol.85 , pp. 329-397
    • Bodenstein, M.1
  • 25
    • 0000292524 scopus 로고
    • A note on the kinetics of enzyme action
    • Briggs G.E., Haldane J.B.S. (1925) A note on the kinetics of enzyme action. Biochemical Journal 19, 338-339.
    • (1925) Biochemical Journal , vol.19 , pp. 338-339
    • Briggs, G.E.1    Haldane, J.B.S.2
  • 26
    • 0003985009 scopus 로고
    • Kinetics for life sciences. Receptors, transmitters and catalysts
    • Cambridge University Press, Cambridge, UK
    • Gutfreund H. (1995) Kinetics for life sciences. Receptors, transmitters and catalysts. Cambridge University Press, Cambridge, UK.
    • (1995)
    • Gutfreund, H.1
  • 27
    • 2142746284 scopus 로고
    • The activated complex in chemical reactions
    • Eyring H. (1935) The activated complex in chemical reactions. J. Chem. Phys. 3, 107-115.
    • (1935) J. Chem. Phys. , vol.3 , pp. 107-115
    • Eyring, H.1
  • 28
    • 33947547892 scopus 로고
    • Molecular architecture and biological reactions
    • Pauling L. (1946) Molecular architecture and biological reactions. Chemical and Engeneering News 24, 1375-1377.
    • (1946) Chemical and Engeneering News , vol.24 , pp. 1375-1377
    • Pauling, L.1
  • 29
    • 0003825088 scopus 로고
    • Statistical Thermodynamics of Nonequilibrium Processes
    • Springer-Verlag, New York
    • Keizer, J. 1987. Statistical Thermodynamics of Nonequilibrium Processes. Springer-Verlag, New York.
    • (1987)
    • Keizer, J.1
  • 30
    • 0020654939 scopus 로고
    • Creatine kinase: structure-activity relationships
    • Kenyon, G. L., Reed, G. H. (1983) Creatine kinase: structure-activity relationships. Adv. Enzymol. 54, 367-426.
    • (1983) Adv. Enzymol. , vol.54 , pp. 367-426
    • Kenyon, G.L.1    Reed, G.H.2
  • 31
  • 32
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to conduction and excitation in nerve
    • Hodgkin A.L., Huxley A.F. (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117, 500-544.
    • (1952) J. Physiol. , vol.117 , pp. 500-544
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 33
    • 73849164199 scopus 로고
    • A modification of the Hodgkin-Huxley equations applicable to Purkinje fiber action and pace-maker potentials
    • Noble D. (1962) A modification of the Hodgkin-Huxley equations applicable to Purkinje fiber action and pace-maker potentials. J. Physiol. 160, 317-352.
    • (1962) J. Physiol. , vol.160 , pp. 317-352
    • Noble, D.1
  • 34
    • 33847175446 scopus 로고    scopus 로고
    • The music of life. Biology beyond the genome
    • Oxford University Press, UK
    • Noble D. (2006) The music of life. Biology beyond the genome. Oxford University Press, UK.
    • (2006)
    • Noble, D.1
  • 35
    • 0014321444 scopus 로고
    • Simulation of the detailed regulation of glycolysis in a heart supernatant preparation
    • Garfinkel D., Frenkel R.A., Garfinkel L. (1968) Simulation of the detailed regulation of glycolysis in a heart supernatant preparation. Comput. Biomed. Res. 2, 68-91.
    • (1968) Comput. Biomed. Res. , vol.2 , pp. 68-91
    • Garfinkel, D.1    Frenkel, R.A.2    Garfinkel, L.3
  • 36
    • 0014258550 scopus 로고
    • Self-oscillations in glycolysis
    • Selkov E.E. (1968) Self-oscillations in glycolysis. Eur. J. Biochem. 4, 79-86.
    • (1968) Eur. J. Biochem. , vol.4 , pp. 79-86
    • Selkov, E.E.1
  • 37
    • 0003381877 scopus 로고
    • Metabolic control mechanisms. V A solution for the equations representing interaction between glycolysis and respiration in ascites tumor cells
    • Chance B., Garfinkel D., Higgins J., Hess B. (1960) Metabolic control mechanisms. V A solution for the equations representing interaction between glycolysis and respiration in ascites tumor cells. J. Biol. Chem. 235, 2426-2439.
    • (1960) J. Biol. Chem. , vol.235 , pp. 2426-2439
    • Chance, B.1    Garfinkel, D.2    Higgins, J.3    Hess, B.4
  • 38
    • 0019879459 scopus 로고
    • Control of energy transformation in mitochondria. Analysis by a quantitative model
    • Bohnensack R. (1981) Control of energy transformation in mitochondria. Analysis by a quantitative model. Biochim. Biophys. Acta 634, 203-218.
    • (1981) Biochim. Biophys. Acta , vol.634 , pp. 203-218
    • Bohnensack, R.1
  • 39
    • 0035975695 scopus 로고    scopus 로고
    • A model of oxidative phosphorylation in mammalian skeletal muscle
    • Korzeniewski, B., Zoladz, J. A. (2001) A model of oxidative phosphorylation in mammalian skeletal muscle. Biophys. Chem. 92, 17-34.
    • (2001) Biophys. Chem. , vol.92 , pp. 17-34
    • Korzeniewski, B.1    Zoladz, J.A.2
  • 40
    • 33748439813 scopus 로고    scopus 로고
    • Oxygen consumption and metabolite concentrations during transitions between different work intensities in heart
    • Korzeniewski, B. (2006) Oxygen consumption and metabolite concentrations during transitions between different work intensities in heart. Am. J. Physiol. 291, H799-H804.
    • (2006) Am. J. Physiol. , vol.291
    • Korzeniewski, B.1
  • 42
    • 0030767184 scopus 로고    scopus 로고
    • Minimal model of b-cell mitochondrial Ca2{thorn} handling
    • Magnus G., Keizer J. (1997) Minimal model of b-cell mitochondrial Ca2{thorn} handling. Am. J. Physiol. 273, C717-C733.
    • (1997) Am. J. Physiol. , vol.273
    • Magnus, G.1    Keizer, J.2
  • 44
    • 12344329199 scopus 로고    scopus 로고
    • Genetic manipulation of calcium-handling proteins. II Mathematical modeling studies
    • Coutu P., Metzger J.M. (2005) Genetic manipulation of calcium-handling proteins. II Mathematical modeling studies. Am. J. Physiol. 288, H613-H631.
    • (2005) Am. J. Physiol. , vol.288
    • Coutu, P.1    Metzger, J.M.2
  • 45
    • 0346850834 scopus 로고    scopus 로고
    • Modeling b-adrenergetic control of cardiac myocyte contractility in silico
    • Saucerman J.J., Brunton L.L., Michailova A.P., McCulloch A.D. (2003) Modeling b-adrenergetic control of cardiac myocyte contractility in silico. J. Biol. Chem. 278, 47997-48003.
    • (2003) J. Biol. Chem. , vol.278 , pp. 47997-48003
    • Saucerman, J.J.1    Brunton, L.L.2    Michailova, A.P.3    McCulloch, A.D.4
  • 46
    • 0030739712 scopus 로고    scopus 로고
    • A general computational framework for modeling cellular structure and function
    • Schaff J., Fink C.C., Slepchenko B., Carson J.H., Loew L. (1997) A general computational framework for modeling cellular structure and function. Biophys. J. 73, 1135-1146.
    • (1997) Biophys. J. , vol.73 , pp. 1135-1146
    • Schaff, J.1    Fink, C.C.2    Slepchenko, B.3    Carson, J.H.4    Loew, L.5
  • 47
    • 0031851349 scopus 로고    scopus 로고
    • Energy balance in muscle activity: simulations of ATPse coupled to oxidative phosphorylation and to creatine kinase
    • Kushmerick M. (1998) Energy balance in muscle activity: simulations of ATPse coupled to oxidative phosphorylation and to creatine kinase. Comp. Biochem. Physiol. 120, 109-123.
    • (1998) Comp. Biochem. Physiol. , vol.120 , pp. 109-123
    • Kushmerick, M.1
  • 48
    • 33749339635 scopus 로고    scopus 로고
    • Modeling of oxygen transport and cellular energetics explains observations on in vivo cardiac energy metabolism
    • Beard D. (2006) Modeling of oxygen transport and cellular energetics explains observations on in vivo cardiac energy metabolism. PLoS Computational Biology. 2, 1093-1106.
    • (2006) PLoS Computational Biology. , vol.2 , pp. 1093-1106
    • Beard, D.1
  • 49
    • 33746809102 scopus 로고    scopus 로고
    • A computational model integrating electrophysiology, contraction and mitochondrial bioenergetics in the ventricle myocyte
    • Cortassa S., Aon M.A., O'Rourke B., Jacques R., Tseng H.J., Marban E., Winslow R. (2006) A computational model integrating electrophysiology, contraction and mitochondrial bioenergetics in the ventricle myocyte. Biophys. J. 91, 1564-1589.
    • (2006) Biophys. J. , vol.91 , pp. 1564-1589
    • Cortassa, S.1    Aon, M.A.2    O'Rourke, B.3    Jacques, R.4    Tseng, H.J.5    Marban, E.6    Winslow, R.7
  • 50
    • 3142617691 scopus 로고    scopus 로고
    • Mathematical and computational techniques to deduce complex biochemical reaction mechanisms
    • Cramplin E.J., Schnell S., McSharry P.E. (2004) Mathematical and computational techniques to deduce complex biochemical reaction mechanisms. Progr. Biophys. Mol. Biol. 86, 77-112.
    • (2004) Progr. Biophys. Mol. Biol. , vol.86 , pp. 77-112
    • Cramplin, E.J.1    Schnell, S.2    McSharry, P.E.3
  • 51
    • 0030992292 scopus 로고    scopus 로고
    • Compartmentalized energy transfer in cardiomyocytes: use of mathematical modeling for analysis of in vivo regulation of respiration
    • Aliev MK, Saks VA. (1997) Compartmentalized energy transfer in cardiomyocytes: use of mathematical modeling for analysis of in vivo regulation of respiration. Biophys. J. 73, 428-445.
    • (1997) Biophys. J. , vol.73 , pp. 428-445
    • Aliev, M.K.1    Saks, V.A.2
  • 52
    • 0034086313 scopus 로고    scopus 로고
    • Regulation of mitochondrial respiration in heart cells analyzed by reactiondiffusion model of energy transfer
    • Vendelin M., Kongas O., Saks V. (2000). Regulation of mitochondrial respiration in heart cells analyzed by reactiondiffusion model of energy transfer. Am. J. Physiol. 278, C747-764.
    • (2000) Am. J. Physiol. , vol.278
    • Vendelin, M.1    Kongas, O.2    Saks, V.3
  • 54
    • 0014008650 scopus 로고
    • The possible role of the mitochondrial bound creatine kinase in regulation of mitochondrial respiration
    • Bessman, S. P., A. Fonyo (1966) The possible role of the mitochondrial bound creatine kinase in regulation of mitochondrial respiration. Biochem. Biophys. Res. Commun. 22:597-602.
    • (1966) Biochem. Biophys. Res. Commun. , vol.22 , pp. 597-602
    • Bessman, S.P.1    Fonyo, A.2
  • 55
    • 0015860346 scopus 로고
    • Creatine kinase of rat heart mitochondria. coupling of creatine phosphorylation to electron transport
    • Jacobus, W. E., A. L. Lehninger. (1973) Creatine kinase of rat heart mitochondria. coupling of creatine phosphorylation to electron transport. J. Biol. Chem. 248:4803-4810.
    • (1973) J. Biol. Chem. , vol.248 , pp. 4803-4810
    • Jacobus, W.E.1    Lehninger, A.L.2
  • 56
    • 0016720206 scopus 로고
    • Studies of energy transport in heart cells. Mitochondrial isoenzyme of creatine phosphokinase: kinetic properties and regulatory action of mg2{thorn} ions
    • Saks, V. A., G. B. Chernousova, D. E. Gukovsky, V. N. Smirnov, E. I. Chazov (1975) Studies of energy transport in heart cells. Mitochondrial isoenzyme of creatine phosphokinase: kinetic properties and regulatory action of mg2{thorn} ions. Eur. J. Biochem. 57:273-290.
    • (1975) Eur. J. Biochem. , vol.57 , pp. 273-290
    • Saks, V.A.1    Chernousova, G.B.2    Gukovsky, D.E.3    Smirnov, V.N.4    Chazov, E.I.5
  • 57
    • 0026585611 scopus 로고
    • Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis
    • Wallimann, T., M. Wyss, D. Brdiczka, K. Nicolay, H. M. Eppenberger (1992) Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem. J. 281: 21-40.
    • (1992) Biochem. J. , vol.281 , pp. 21-40
    • Wallimann, T.1    Wyss, M.2    Brdiczka, D.3    Nicolay, K.4    Eppenberger, H.M.5
  • 58
    • 0019471878 scopus 로고
    • Transport of energy in muscle: the phosphorylcreatine shuttle
    • Bessman, S. P., P. J. Geiger (1981) Transport of energy in muscle: the phosphorylcreatine shuttle. Science 211:448-452.
    • (1981) Science , vol.211 , pp. 448-452
    • Bessman, S.P.1    Geiger, P.J.2
  • 59
    • 0020214568 scopus 로고
    • Creatine kinase of heart mitochondria: changes in its kinetic properties induced by coupling to oxidative phosphorylation
    • Jacobus, W. E., V. A. Saks (1982) Creatine kinase of heart mitochondria: changes in its kinetic properties induced by coupling to oxidative phosphorylation. Arch. Biochem. Biophys. 219:167-178.
    • (1982) Arch. Biochem. Biophys. , vol.219 , pp. 167-178
    • Jacobus, W.E.1    Saks, V.A.2
  • 60
    • 0021243540 scopus 로고
    • Effect of creatine kinase activity on mitochondrial ADP/ATP transport. Evidence for a functional interaction
    • Barbour, R. L., J. Ribaudo, S. H. Chan (1984) Effect of creatine kinase activity on mitochondrial ADP/ATP transport. Evidence for a functional interaction. J. Biol. Chem. 259:8246-8251.
    • (1984) J. Biol. Chem. , vol.259 , pp. 8246-8251
    • Barbour, R.L.1    Ribaudo, J.2    Chan, S.H.3
  • 61
    • 0020402772 scopus 로고
    • Control of heart mitochondrial oxygen consumption by creatine kinase: the importance of enzyme localization
    • Gellerich, F., V. A. Saks (1982) Control of heart mitochondrial oxygen consumption by creatine kinase: the importance of enzyme localization. Biochem. Biophys. Res. Commun. 105:1473-1481.
    • (1982) Biochem. Biophys. Res. Commun. , vol.105 , pp. 1473-1481
    • Gellerich, F.1    Saks, V.A.2
  • 62
    • 0023144106 scopus 로고
    • Dynamic compartmentation of adenine nucleotides in the mitochondrial intermembrane space of rat-heart mitochondria
    • Gellerich, F. N., M. Schlame, R. Bohnensack, W. Kunz (1987) Dynamic compartmentation of adenine nucleotides in the mitochondrial intermembrane space of rat-heart mitochondria. Biochim. Biophys. Acta. 890:117-126.
    • (1987) Biochim. Biophys. Acta. , vol.890 , pp. 117-126
    • Gellerich, F.N.1    Schlame, M.2    Bohnensack, R.3    Kunz, W.4
  • 63
    • 0027199664 scopus 로고
    • Quantitative analysis of the 'phosphocreatine shuttle': I. a probability approach to the description of phosphocreatine production in the coupled creatine kinase-atp/adp translocase-oxidative phosphorylation reactions I
    • Aliev, M. K., V. A. Saks (1993) Quantitative analysis of the 'phosphocreatine shuttle': I. a probability approach to the description of phosphocreatine production in the coupled creatine kinase-atp/adp translocase-oxidative phosphorylation reactions I. Biochim. Biophys. Acta. 1143:291-300.
    • (1993) Biochim. Biophys. Acta. , vol.1143 , pp. 291-300
    • Aliev, M.K.1    Saks, V.A.2
  • 64
    • 0028101488 scopus 로고
    • Mathematical modeling of intracellular transport processes and the creatine kinase systems: a probability approach
    • Aliev, M. K., V. A. Saks (1994) Mathematical modeling of intracellular transport processes and the creatine kinase systems: a probability approach. Mol. Cell. Biochem. 133-134:333-346.
    • (1994) Mol. Cell. Biochem. , vol.133-134 , pp. 333-346
    • Aliev, M.K.1    Saks, V.A.2
  • 65
    • 3042857526 scopus 로고    scopus 로고
    • Analysis of functional coupling: Mitochondrial creatine kinase and adenine nucleotide translocase
    • Vendelin, M., M. Lemba, V. Saks (2004) Analysis of functional coupling: Mitochondrial creatine kinase and adenine nucleotide translocase. Biophys. J. 87:696-713.
    • (2004) Biophys. J. , vol.87 , pp. 696-713
    • Vendelin, M.1    Lemba, M.2    Saks, V.3
  • 66
    • 0016180488 scopus 로고
    • Theoretical formalism for the sliding filament model of contraction of striated muscle. Part I
    • Hill, T. L. 1974. Theoretical formalism for the sliding filament model of contraction of striated muscle. Part I. Prog. Biophys. Mol. Biol. 28:267-340.
    • (1974) Prog. Biophys. Mol. Biol. , vol.28 , pp. 267-340
    • Hill, T.L.1
  • 67
    • 0016612016 scopus 로고
    • Some self-consistent twostate sliding filament models of muscle contraction
    • Hill, T. L., E. Eisenberg, Y. D. Chen, R. J. Podolsky. 1975. Some self-consistent twostate sliding filament models of muscle contraction. Biophys. J. 15:335-372.
    • (1975) Biophys. J. , vol.15 , pp. 335-372
    • Hill, T.L.1    Eisenberg, E.2    Chen, Y.D.3    Podolsky, R.J.4
  • 68
    • 0032750787 scopus 로고    scopus 로고
    • Mechanochemical coupling in spinlabeled, active, isometric muscle
    • Baker, LaConte, Brust-Mascher, Thomas. 1999. Mechanochemical coupling in spinlabeled, active, isometric muscle. Biophys. J. 77:2657-2664.
    • (1999) Biophys. J. , vol.77 , pp. 2657-2664
    • Baker, L.1    Brust-Mascher, T.2
  • 69
    • 0033798645 scopus 로고    scopus 로고
    • Thermodynamics and kinetics of a molecular motor ensemble
    • Baker, J. E., D. D. Thomas. 2000. Thermodynamics and kinetics of a molecular motor ensemble. Biophys. J. 79:1731-1736.
    • (2000) Biophys. J. , vol.79 , pp. 1731-1736
    • Baker, J.E.1    Thomas, D.D.2
  • 70
    • 0033865068 scopus 로고    scopus 로고
    • Muscle cross-bridge chemistry and force
    • Highsmith, S. 2000. Muscle cross-bridge chemistry and force. Biophys. J. 79:1686-1687.
    • (2000) Biophys. J. , vol.79 , pp. 1686-1687
    • Highsmith, S.1
  • 71
    • 0347363559 scopus 로고    scopus 로고
    • Elastic energy storage in beta-sheets with application to F1-ATPase
    • Sun, S., D. Chandler, A. R. Dinner, G. Oster. 2003. Elastic energy storage in beta-sheets with application to F1-ATPase. Eur. Biophys. J. 32:676-683.
    • (2003) Eur. Biophys. J , vol.32 , pp. 676-683
    • Sun, S.1    Chandler, D.2    Dinner, A.R.3    Oster, G.4
  • 72
    • 1542375372 scopus 로고    scopus 로고
    • Asymmetry in the F1-ATPase and its implications for the rotational cycle
    • Sun, S. X., H. Wang, G. Oster. 2004. Asymmetry in the F1-ATPase and its implications for the rotational cycle. Biophys. J. 86:1373-1384.
    • (2004) Biophys. J. , vol.86 , pp. 1373-1384
    • Sun, S.X.1    Wang, H.2    Oster, G.3
  • 74
    • 0025321502 scopus 로고
    • Ventricular energetics
    • Suga, H. 1990. Ventricular energetics. Physiol. Rev. 70:247-277.
    • (1990) Physiol. Rev. , vol.70 , pp. 247-277
    • Suga, H.1
  • 75
    • 0023232136 scopus 로고
    • Correlation of force-length area with oxygen consumption in ferret papillary muscle
    • Hisano, R., G. Cooper. 1987. Correlation of force-length area with oxygen consumption in ferret papillary muscle. Circ. Res. 61:318-328.
    • (1987) Circ. Res. , vol.61 , pp. 318-328
    • Hisano, R.1    Cooper, G.2
  • 76
    • 0027686620 scopus 로고
    • Comparison of the cardiac forcetime integral with energetics using a cardiac muscle model
    • Taylor, T. W., Y. Goto, K. Hata, T. Takasago, A. Saeki, T. Nishioka, H. Suga. 1993a. Comparison of the cardiac forcetime integral with energetics using a cardiac muscle model. J. Biomech. 26:1217-1225.
    • (1993) J. Biomech. , vol.26 , pp. 1217-1225
    • Taylor, T.W.1    Goto, Y.2    Hata, K.3    Takasago, T.4    Saeki, A.5    Nishioka, T.6    Suga, H.7
  • 77
    • 0027480190 scopus 로고
    • Variable cross-bridge cycling-atp coupling accounts for cardiac mechanoenergetics
    • Taylor, T. W., Y. Goto, H. Suga. 1993b. Variable cross-bridge cycling-atp coupling accounts for cardiac mechanoenergetics. Am. J. Physiol. 264:H994-1004.
    • (1993) Am. J. Physiol. , vol.264
    • Taylor, T.W.1    Goto, Y.2    Suga, H.3
  • 78
    • 0036350660 scopus 로고    scopus 로고
    • Optimizing ventricular fibers: uniform strain or stress, but not ATP consumption, leads to high efficiency
    • Vendelin, M., P. H. Bovendeerd, J. Engelbrecht, T. Arts. 2002. Optimizing ventricular fibers: uniform strain or stress, but not ATP consumption, leads to high efficiency. Am. J. Physiol. 283:H1072-H1081.
    • (2002) Am. J. Physiol. , vol.283
    • Vendelin, M.1    Bovendeerd, P.H.2    Engelbrecht, J.3    Arts, T.4
  • 79
    • 0028855563 scopus 로고
    • Force, not sarcomere length, correlates with prolongation of isosarcometric contraction
    • Janssen, P. M., W. C. Hunter. 1995. Force, not sarcomere length, correlates with prolongation of isosarcometric contraction. Am. J. Physiol. 269:H676-H685.
    • (1995) Am. J. Physiol. , vol.269
    • Janssen, P.M.1    Hunter, W.C.2
  • 81
    • 0003676983 scopus 로고
    • La nouvelle alliance
    • Collection Folio. Les Editions Gallimard, Paris
    • Prigogine I., Strengers I. (1986) La nouvelle alliance. Collection Folio. Les Editions Gallimard, Paris.
    • (1986)
    • Prigogine, I.1    Strengers, I.2
  • 82
    • 33845585832 scopus 로고    scopus 로고
    • Systems biology approaches to metabolic and cardiovascular disorders: network perspectives of cardiovascular metabolism
    • Weiss J.N., Yang L., Qu Z. (2006) Systems biology approaches to metabolic and cardiovascular disorders: network perspectives of cardiovascular metabolism. J. Lipid. Res. 47, 2355-2366.
    • (2006) J. Lipid. Res. , vol.47 , pp. 2355-2366
    • Weiss, J.N.1    Yang, L.2    Qu, Z.3
  • 83
    • 33645897315 scopus 로고    scopus 로고
    • Cardiac system bioenergetics: metabolic basis of Frank-Starling law
    • Saks, V., Dzeja, P., Schlattner, U., Vendelin, M., Terzic, A., Wallimann, T. (2006b) Cardiac system bioenergetics: metabolic basis of Frank-Starling law. J. Physiol. 571 (2), 253-273.
    • (2006) J. Physiol. , vol.571 , Issue.2 , pp. 253-273
    • Saks, V.1    Dzeja, P.2    Schlattner, U.3    Vendelin, M.4    Terzic, A.5    Wallimann, T.6
  • 84
    • 33845335159 scopus 로고    scopus 로고
    • Molecular System Bioenergetics: regulation of substrate supply in response to heart energy demands
    • Saks V., Favier R., Guzun R., Schlattner U., Wallimann T. (2006) Molecular System Bioenergetics: regulation of substrate supply in response to heart energy demands. J. Physiol. 577, 769-777.
    • (2006) J. Physiol. , vol.577 , pp. 769-777
    • Saks, V.1    Favier, R.2    Guzun, R.3    Schlattner, U.4    Wallimann, T.5
  • 85
    • 2442543316 scopus 로고    scopus 로고
    • Reaction kinetics in intracellular environments with macromolecular crowding: stimulation and rate laws
    • Schell S., Turner T.E. (2004) Reaction kinetics in intracellular environments with macromolecular crowding: stimulation and rate laws. Progr. Biophys. Mol. Biol. 85, 235-260.
    • (2004) Progr. Biophys. Mol. Biol. , vol.85 , pp. 235-260
    • Schell, S.1    Turner, T.E.2
  • 86
    • 3142600919 scopus 로고    scopus 로고
    • Discret-event, multi-level simulation of metabolite channeling
    • Degenring D., Rohl M., Uhrmacher A.M. (2004) Discret-event, multi-level simulation of metabolite channeling. BioSystems 75, 29-41.
    • (2004) BioSystems , vol.75 , pp. 29-41
    • Degenring, D.1    Rohl, M.2    Uhrmacher, A.M.3
  • 88
    • 4143118798 scopus 로고    scopus 로고
    • Signaling in small subcellular volumes. I. Stochastic and diffusion effects on individual pathways
    • Bhalla U.S. (2004) Signaling in small subcellular volumes. I. Stochastic and diffusion effects on individual pathways. Biophys. J. 87, 733-744.
    • (2004) Biophys. J. , vol.87 , pp. 733-744
    • Bhalla, U.S.1
  • 89
    • 0034733820 scopus 로고    scopus 로고
    • Regulating the cellular economy of supply and demand
    • Hofmeyr J.H., Cornish-Bowden, A. (2000) Regulating the cellular economy of supply and demand. FEBS Letters 476, 47-51.
    • (2000) FEBS Letters , vol.476 , pp. 47-51
    • Hofmeyr, J.H.1    Cornish-Bowden, A.2
  • 90
    • 0029002581 scopus 로고
    • Composite control of cell function: metabolic pathways behaving as single control units
    • Kholodenko B.N., Schuster S., Rohwer J.M., Cascante M., Westerhoff H. (1995) Composite control of cell function: metabolic pathways behaving as single control units. FEBS Let. 368, 1-4.
    • (1995) FEBS Let. , vol.368 , pp. 1-4
    • Kholodenko, B.N.1    Schuster, S.2    Rohwer, J.M.3    Cascante, M.4    Westerhoff, H.5
  • 91
    • 84889309787 scopus 로고    scopus 로고
    • Mathematical modelling of cardiac mechanoenergetics
    • editors G. Holzapfel, K. Ogden, Springer-Verlag, Berlin
    • Engelbrecht, J., M. Vendelin. 2006. Mathematical modelling of cardiac mechanoenergetics. In Mechanics of Biological Tissue, Proc. IUTAM Symp., editors G. Holzapfel, K. Ogden, 369-378, Springer-Verlag, Berlin.
    • (2006) Mechanics of Biological Tissue, Proc. IUTAM Symp. , pp. 369-378
    • Engelbrecht, J.1    Vendelin, M.2


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