Enhanced chemotherapy sensitivity of human colon cancer cells to 5-fluorouracil by siRNA recombinant expression vector targeting survivin gene

Chinese Medical Sciences Journal

Volumn 24, Issue 2, 2009, Pages 97-101

  Cai, Ming ^a   Wang, Guo Bin ^a   Tao, Kai Xiong ^a   Cai, Chang Xue ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Chemotherapy; Gene therapy; RNA interference; Survivin

Indexed keywords

FLUOROURACIL; SMALL INTERFERING RNA; SURVIVIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; EXPRESSION VECTOR; FLOW CYTOMETRY; GENE CONSTRUCT; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RESTRICTION MAPPING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

EID: 67650802539     PISSN: 10019294     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1001-9294(09)60069-9     Document Type: Article

References (20)

1. Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411:494-498 (Pubitemid 32494397)
2. Mittal V. Improving the efficiency of RNA interference in mammals. Nat Rev Genet 2004; 5:355-365 (Pubitemid 38529407)
3. Moffat J, Sabatini DM. Building mammalian signalling pathways with RNAi screens. Nat Rev Mol Cell Biol 2006; (3): 177-187 (Pubitemid 43297947)
4. Kim DH, Rossi JJ. Strategies for silencing human disease using RNA interference. Nat Rev Genet 2007; 8:173-184
5. Fuessel S, Herrmann J, Ning S, et al. Chemosensitization of bladder cancer cells by survivin-directed antisense oligodeoxynucleotides and siRNA. Cancer Lett 2006; 232: 243-254 (Pubitemid 43170974)
6. Duffy MJ, O'Donovan N, Brennan DJ, et al. Survivin: a promising tumor biomarker. Cancer Lett 2007; 249:49-60.
7. Pennati M, Folini M, Zaffaroni N. Targeting survivin in cancer therapy: fulfilled promises and open questions. Carcinogenesis, 2007; 28:1133-1139 (Pubitemid 47062670)
8. Rosa J, Canovas P, Islam A, et al. Survivin modulates microtubule dynamics and nucleation throughout the cell cycle. Mol Biol Cell 2006; 17:1483-1493 (Pubitemid 43376565)
9. Altieri DC. The case for survivin as a regulator of microtubule dynamics and cell-death decisions. Curr Opin Cell Biol 2006; 18:609-615
10. Vong QP, Cao K, Li HY. Chromosome alignment and segregation regulated by ubiquitination of survivin. Science 2005; 310:1443-1444 (Pubitemid 41746347)
11. Dohi T, Beltrami E, Wall NR, et al. Mitochondrial survivin inhibits apoptosis and promotes tumorigenesis. J Clin Invest 2004; 14:1117-1127 (Pubitemid 39578701)
12. Altieri DC. Molecular circuits of apoptosis regulation and cell division control: the survivin paradigm. J Cell Biochem 2004; 92:656-663
13. Zaffaroni N, Pennati M, Daidone MG. Survivin as a target for new anticancer interventions. J Cell Mol Med 2005; 9:360-372
14. Blanc-Brude OP, Yu J, Simosa H, et al. Inhibitor of apoptosis protein survivin regulates vascular injury. Nat Med 2002; 8:987-994 (Pubitemid 35033703)
15. Kawasaki H, Toyoda M, Shinohara H, et al. Expression of survivin correlates with apoptosis, proliferation, and angiogenesis during human colorectal tumorigenesis. Cancer 2001; 91:2026-2032 (Pubitemid 32476366)
16. Takai N, Miyazaki T, Nishida M, et al. Survivin expression correlates with clinical stage, histological grade, invasive behavior and survival rate in endometrial carcinoma. Cancer Lett 2002; 184:105-116 (Pubitemid 34718112)
17. Falleni M, Pellegrini C, Marchetti A, et al. Survivin gene expression in early-stage non-small cell lung cancer. J Pathol 2003; 200:620-626 (Pubitemid 36987311)
18. Kountouras J, Zavos C, Chatzopoulos D. Apoptotic and anti-angiogenic strategies in liver and gastrointestinal malignancies. J Surg Oncol 2005; 90:249-259 (Pubitemid 40770941)
19. Grabowski P, Kühnel T, Mühr-Wilkenshoff F, et al. Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma. BrJ Cancer 2003; 88:115-119 (Pubitemid 36241227)
20. Lin LJ, Zheng CQ, Jin Y, et al. Expression of survivin protein in human colorectal carcinogenesis. World J Gastroenterol 2003; 9:974-977 (Pubitemid 36681663)