Pro-angiogenic activity of Urotensin-II on different human vascular endothelial cell populations

Regulatory Peptides

Volumn 157, Issue 1-3, 2009, Pages 64-71

  Albertin, Giovanna ^a   Guidolin, Diego ^a   Sorato, Elisa ^a   Spinazzi, Raffaella ^a   Mascarin, Alessandra ^a   Oselladore, Barbara ^a   Montopoli, Monica ^a   Antonello, Michele ^a   Ribatti, Domenico ^b  

^a UNIVERSITY OF PADUA MEDICAL SCHOOL   (Italy)

^b UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

Author keywords

Angiogenesis; Human endothelial cells; Matrigel assay; Urotensin receptor; Urotensin II

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA; PEPTIDE; UROTENSIN II; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

ANGIOGENESIS; AORTA; ARTICLE; CARDIOVASCULAR FUNCTION; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOHISTOCHEMISTRY; NEOVASCULARIZATION, PHYSIOLOGIC; PHENOTYPE; QUINOLINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UREA; UROTENSINS;

EID: 67650800478     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2009.04.006     Document Type: Article

References (47)

1. Pearson D., Shively J.E., Clark B.R., Geschwind I.I., Barkley M., Nishioka R.S., et al. Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes. Proc Natl Acad Sci USA 77 (1980) 5021-5024
2. Coulouarn Y., Lihrmann I., Jegou S., Anouar Y., Tostivint H., and Beauvillain J.C. Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurons of the spinal cord. Proc Natl Acad Sci USA 95 (1998) 15803-15808
3. Nothacker H.P., Wang Z., McNeill A.M., Saito Y., Merten S., O'Dowd B., et al. Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction. Nat Cell Biol 1 (1999) 383-385
4. Ames R.S., Sarau H.M., Cambers J.K., Willette R.N., Aiyar N.V., Romanic A.M., et al. Human urotensin II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature 401 (1999) 282-286
5. Davenport A.P., and Maguire J.J. Urotensin II: fish neuropeptide catches orphan receptor. Trends Pharmacol Sci 21 (2000) 80-92
6. Douglas S.A., and Ohlstein E.H. Human urotensin-II, the most potent mammalian vasoconstrictor identified to date, as a therapeutic target for the management of cardiovascular disease. Trends Cardiovasc Med 10 (2000) 229-237
7. Maguire J.J., Kuc R.E., and Davenport A.P. Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1. Br J Pharmacol 131 (2000) 441-446
8. Maguire J.J., Kuc R.E., Kleinz M.J., and Davenport A.P. Immunocytochemical localization of the urotensin-II receptor, UT, to rat and human tissues: relevance to function. Peptides 29 (2008) 735-742
9. Yoshimoto T., Matsushita M., and Hirata Y. Role of urotensin II in peripheral tissues as an autocrine/paracrine growth factor. Peptides 25 (2004) 1775-1781
10. Albertin G., Casale V., Ziolkowska A., Spinazzi R., Malendowicz L.K., Rossi G.P., et al. Urotensin-II and UII-receptor expression and function in the rat adrenal cortex. Int J Mol Med 17 (2006) 1111-1115
11. Douglas S.A. Human urotensin-II as a novel cardiovascular target: "heart" of the matter or simply a fishy "tail"?. Curr Opin Pharmacol 3 (2003) 159-167
12. Cheung B.M.Y., Leung R., Man Y.B., and Wong L.Y.F. Plasma concentration of urotensin II is raised in hypertension. J Hypertens 22 (2004) 1341-1344
13. Douglas S.A., Tayara L., Ohlstein E.H., Halawa N., and Giaid A. Congestive heart failure and expression of myocardial urotensin II. Lancet 359 (2002) 1990-1997
14. Russel F.D., and Molenaar P. Cardiovascular actions of human urotensin II: considerations for hypertension. Naunyn-Schmiedeberg's Arch Pharmacol 369 (2004) 271-273
15. Thanassoulis G., Huyhn T., and Giaid A. Urotensin II and cardiovascular diseases. Peptides 25 (2004) 1789-1794
16. Suguro T., Watanabe T., Ban Y., Kodate S., Misaki A., Hirano T., et al. Increased human urotensin II levels are correlated with carotid atherosclerosis in essential hypertension. Am J Hypertens 20 (2007) 211-217
17. Bousette N., Patel L., Douglas S.A., Ohlstein E.H., and Giaid A. Increased expression of urotensin II and its cognate receptor GPR14 in atherosclerotic lesions of the human aorta. Atherosclerosis 176 (2004) 117-123
18. Hassan G.S., Douglas S.A., Ohlstein E.H., and Giaid A. Expression of urotensin-II in human coronary atherosclerosis. Peptides 26 (2005) 2464-2472
19. Heringlake M., Kox T., Uzun O., Will B., Bahlmann L., Klaus S., et al. The relationship between urotensin II plasma immunoreactivity and left ventricular filling pressures in coronary artery disease. Regul Pept 121 (2004) 129-136
20. Maguire J.J., Kuc R.E., Wiley K.E., Kleinz M.J., and Davenport A.P. Cellular distribution of immunoreactive urotensin-II in human tissues with evidence of increased expression in atherosclerosis and a greater constrictor response of small compared to large coronary arteries. Peptides 25 (2004) 1767-1774
21. MacLean M.R., Alexander D., Stirrat A., Gallagher M., Douglas S.A., Ohlstein E.H., et al. Contractile responses to human urotensin-II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat. Br J Pharmacol 130 (2000) 201-204
22. Spinazzi R., Albertin G., Nico B., Guidolin D., Di Liddo R., Rossi G.P., et al. Urotensin-II and its receptor (UT) are expressed in rat brain endothelial cells, and urotensin-II via UT stimulates angiogenesis in vivo and in vitro. Int J Mol Med 18 (2006) 1107-1112
23. Garlanda C., and Dejana E. Heterogeneity of endothelial cells. Specific markers. Arterioscler Thromb Vasc Biol 17 (1997) 1193-1202
24. Chi J.T., Chang H.Y., Haraldsen G., Jahnsen F.L., Troyanskaya O.G., and Chang D.S. Endothelial cell diversity revealed by global expression profiling. Proc Natl Acad Sci USA 100 (2003) 10623-10628
25. Deng D.X., Tsalenko A., Vailaya A., Ben-Dor A., Kundu R., Estay I., et al. Differences in vascular bed disease susceptibility reflect differences in gene expression response to atherogenic stimuli. Circ Res 92 (2006) 200-208
26. Clozel M., Binkert C., Birker-Robaczewska M., Boukhadra C., Ding S.S., Fischli W., et al. Pharmacology of the urotensin-II receptor antagonist palosuran (ACT-058362; 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulfate salt): first demonstration of a pathophysiological role of the urotensin system. J Pharmacol Exp Ther 311 (2004) 204-212
27. Conconi M.T., Lora S., Baiguera S., Boscolo E., Folin M., Scienza R., et al. In vitro culture of rat neuromicrovascular endothelial cells on polymeric scaffolds. J Biomed Mater Res 71 (2004) 669-674
28. Conconi M.T., Baiguera S., Guidolin D., Furlan C., Menti A.M., Vigolo S., et al. Effects of hyperbaric oxygen on proliferative and apoptotic activities and reactive oxygen species generation in mouse fibroblast 3T3/J2 cell line. J Investig Med 51 (2003) 227-232
29. Guidolin D., Vacca A., Nussdorfer G.G., and Ribatti D. A new image analysis method based on topological and fractal parameters to evaluate the angiostatic activity of docetaxel by using the Matrigel assay in vitro. Microvasc Res 67 (2004) 117-124
30. Albertin G., Carraro G., and Nussdorfer G.G. Human adrenomedullin gene silencing by short interefering RNAs: a preliminary study. Int J Mol Med 15 (2005) 579-583
31. Albertin G., Rucinski M., Carraro G., Forneris M., Andreis P.G., Malendowicz L.K., et al. Adrenomedullin and vascular endothelium growth factor genes are overexpressed in the regenerating rat adrenal cortex, and AM and VEGF reciprocally enhance their mRNA expression in cultured rat adrenocortical cells. Int J Mol Med 16 (2005) 431-435
32. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acid Res 29 (2001) e45
33. ©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acid Res 30 (2002) e36
34. Zhang Y., Li Y., Wei R., Wang Z., Bu D., Zhao J., et al. Urotensin II is an autocrine/paracrine growth factor for aortic adventitia of rat. Regul Pept 151 (2008) 88-94
35. Tian L., Li C., Qi J., Fu P., Yu X., Li X., et al. Diabetes-induced upregulation of urotensin II and its receptor plays an important role in TGF-β1-mediated renal fibrosis and dysfunction. Am J Physiol Endocrinol Metab 295 (2008) E1234-E1242
36. Ribatti D., Vacca A., and Presta M. The discovery of angiogenic factors: a historical review. Gen Pharmacol 35 (2002) 227-231
37. Olsson A.K., Dimberg A., Kreuger J., and Claesson-Welsh L. VEGF receptor signalling in control of vascular function. Nat Rev 7 (2006) 359-371
38. Rusnati M., and Presta M. Fibroblast growth factors/fibroblast growth factor receptors as targets for the development of anti-angiogenic strategies. Curr Pharm Des 13 (2007) 2025-2044
39. Lang I., Schweizer A., Hiden U., Ghaffari-Tabrizi N., Hagendorfer G., Bilban M., et al. Human fetal placental endothelial cells have a mature arterial and a juvenile venous phenotype with adipogenic and osteogenic differentiation potential. Differentiation 76 (2008) 1031-1043
40. Zhang Y., Fisher N., Newey S.E., Smythe J., Tatton L., Tsaknakis G., et al. The impact of proliferative potential of umbilical cord-derived endothelial progenitor cells and hypoxia on vascular tubule formation in vitro. Stem Cells Dev 18 (2009) 359-375
41. Ribatti D., Nico B., Crivellato E., Roccaro A.M., and Vacca A. The history of the angiogenic switch concept. Leukemia 21 (2007) 44-52
42. Sporn M.B., and Roberts A. Peptide growth factors are multifunctional. Nature 332 (1988) 217-219
43. Fernandez-Sauze S., Delfino C., Mabrouk K., Dussert C., Chinot O., Martin P.M., et al. Effects of adrenomedullin on endothelial cells in the multistep process of angiogenesis: involvement of CRLR/RAMP2 and CRLR/RAMP3 receptors. Int J Cancer 108 (2004) 797-804
44. Guidolin D., Nico B., Belloni A.S., Nussdorfer G.G., Vacca A., and Ribatti D. Morphometry and mathematical modelling of the capillary-like patterns formed in vitro by bone marrow macrophages of patients with multiple myeloma. Leukemia 21 (2007) 2201-2203
45. Helmlinger G., Endo M., Ferrara N., Hlatki L., and Jain R.K. Formation of endothelial cell networks. Nature 405 (2000) 139-141
46. Merks R.M.H., Brodsky S.V., Goligorksy M.S., Newman S.A., and Glazier J.A. Cell elongation is key to in silico replication of in vitro vasculogenesis and subsequent remodeling. Dev Biol 289 (2006) 44-54
47. Watanabe T., Kanome T., Miyazaki A., and Katagiri T. Human urotensin II as a link between hypertension and coronary artery disease. Hypertens Res 29 (2006) 375-387