Fumagillin inhibits colorectal cancer growth and metastasis in mice: In vivo and in vitro study of anti-angiogenesis

Pathology International

Volumn 59, Issue 7, 2009, Pages 448-461

  Hou, Li ^a   Mori, Daisuke ^b   Takase, Yukari ^a   Meihua, Piao ^a   Kai, Keita ^a   Tokunaga, Osamu ^a  

^a SAGA UNIVERSITY   (Japan)

^b Saga Prefectural Hospital Koseikan   (Japan)

Author keywords

Angiogenesis; Colon cancer; Fumagillin; HUVEC; SCID mouse

Indexed keywords

ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; ANGIOGENESIS INHIBITOR; CYCLIN E; CYCLIN E2; CYCLO; ENDOGLIN; FUMAGILLIN; INTERCELLULAR ADHESION MOLECULE 1; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; DENSITY; DOWN REGULATION; ENDOTHELIUM CELL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MALE; METASTASIS INHIBITION; MICROARRAY ANALYSIS; MICROVASCULATURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCID MOUSE; TUMOR VOLUME; UMBILICAL CORD; UPREGULATION; WEIGHT; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; ANIMALS; BLOTTING, WESTERN; COLORECTAL NEOPLASMS; CYCLOHEXANES; ENDOTHELIAL CELLS; FATTY ACIDS, UNSATURATED; FETAL BLOOD; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, SCID; NEOVASCULARIZATION, PATHOLOGIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SESQUITERPENES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 67650799640     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2009.02393.x     Document Type: Article

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