Con: House dust mites in atopic diseases - Accused for 45 years but not guilty?

American Journal of Respiratory and Critical Care Medicine

Volumn 180, Issue 2, 2009, Pages 113-119

  Von Hertzen, Leena ^a   Haahtela, Tari ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

HOUSE DUST ALLERGEN; ALLERGEN;

ASTHMA; ATOPY; CLINICAL FEATURE; DERMATOPHAGOIDES; DISEASE ASSOCIATION; EDITORIAL; ENVIRONMENTAL EXPOSURE; HUMAN; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; MEDICAL LITERATURE; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR; SENSITIZATION; WHEEZING; ANIMAL; CHILD; IMMUNOLOGY; INFANT; NOTE; PHYSIOLOGY; PRESCHOOL CHILD; PYROGLYPHIDAE;

ALLERGENS; ANIMALS; ASTHMA; CHILD; CHILD, PRESCHOOL; HUMANS; IMMUNE TOLERANCE; INFANT; PYROGLYPHIDAE; RISK FACTORS;

EID: 67650730836     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200807-1001CO     Document Type: Editorial

References (57)

1. Voorhorst R, Spieksma-Boezeman ML, Spieksma FT. Is a mite (Dermatophagoides sp.) the producer of the house dust allergen? Allerg Asthma (Leipz) 1964;10:329-334.
2. Sporik R, Holgate ST, Platts-Mills TAE, Cogswell JJ. Exposure to house dust mite allergen (Der p1) and the development of asthma in childhood. A prospective study. N Engl J Med 1990;323:502-507. (Pubitemid 20260050)
3. Sporik R, Chapman MD, Platts-Mills TAE. House dust mite as a cause of asthma. Clin Exp Allergy 1992;22:897-906.
4. Kuehr J, Frischer T, Meinert R, Barth R, Forster J, Schraub S, Urbanek R, Karmaus W. Mite allergen exposure is a risk for the incidence of specific sensitization. J Allergy Clin Immunol 1994;94:44-52. (Pubitemid 24219658)
5. Wahn U, Lau S, Bergmann R, Kulig M, Forster J, Bergmann K, Bauer CP, Guggenmors-Holzmann I. Indoor allergen exposure is a risk factor for sensitisation during the first three years of life. J Allergy Clin Immunol 1997;99:763-769. (Pubitemid 27280366)
6. Pearce N, Douwes J, Beasley R. Is allergen exposure the major primary cause of asthma? Thorax 2000;55:424-431.
7. Holt PG, Thomas WR. Sensitization to airborne environmental allergens: unresolved issues. Nat Immunol 2005;6:957-960.
8. Gotzsche PC, Johansen HK. Housedust mite control measures for asthma. The Cochrane Database of Systematic Reviews 2008; Issue 1: CD001187.
9. Sheikh A, Hurwitz B. House dust mite avoidance measures for perennial allergic rhinitis: a systematic review of efficacy. Br J Gen Pract 2003; 53:318-322. (Pubitemid 36456999)
10. Cullinan P, MacNeill SJ, Harris JM, Moffat S, White C, Mills P, Newman Taylor AJ. Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study. Thorax 2004;59:855-861. (Pubitemid 39389625)
11. Arlian LG, Platts-Mils TAE. The biology of dust mites and the remediation of mite allergens in allergic disease. J Allergy Clin Immunol 2001;107:S406-S413.
12. Gisi U. Bodenökologie. Stuttgart, Germany: Georg Thieme Verlag; 1997.
13. Voorhorst R, Spieksma FTM, Varekamp H, Leupen MJ, Lyklema AW. The house-dust mite (Dermatophagoides pteronyssinus) and the allergens it produces: identity with the house-dust allergen. J Allergy 1967; 39:325-339.
14. Thomas WR, Smith WA, Hales BJ, Mills KL, O'Brien RM. Characterization and immunobiology of house dust mite allergens. Int Arch Allergy Immunol 2002;129:1-18. (Pubitemid 35316844)
15. von Mutius E. Paediatric origin of adult lung disease. Thorax 2001;56: 153-157. (Pubitemid 32142683)
16. Burr ML, Limb ES, Maguire MJ, Amarah L, Eldridge BA, Layzell JM, Merrett TG. Infant feeding, wheezing, and allergy: a prospective study. Arch Dis Child 1993;68:724-728. (Pubitemid 23199854)
17. Boner A, Pescollderungg L, Silverman M. The role of house dust mite elimination in the management of childhood asthma: an unresolved issue. Allergy 2002;57:23-31. (Pubitemid 35238665)
18. Bergmann R, Woodcock A. Whole population or high-risk group? Eur Respir J 1998;12:9S-12S.
19. Arbes SJ, Gergen PJ, Vaughn B. Asthma cases attributable to atopy: results from the Third National Health and Nutrition Examination Survey. J Allergy Clin Immunol 2007;120:1139-1145. (Pubitemid 350029902)
20. Bousquet J, Anto JM, Bachert C, Bousquet PJ, Colombo P, Crameri R, Daëron M, Fokkens W, Leynaert B, Lahoz C, et al. Factors responsible for differences between asymptomatic subjects and patients presenting an IgE sensitisation to allergens. A GA2LEN project. Allergy 2006;61:671-680. (Pubitemid 43801400)
21. Vartiainen E, Petäys T, Haahtela T, Jousilahti P, Pekkanen J. Allergic diseases, skin prick test responses, and IgE levels in North Karelia, Finland, and the Republic of Karelia, Russia. J Allergy Clin Immunol 2002;109:643-648. (Pubitemid 34327191)
22. von Hertzen L, Mäkelä MJ, Petäys T, Jousilahti P, Kosunen TU, Laatikainen T, Vartiainen E, Haahtela T. Growing disparities in atopy between the Finns and the Russians -a comparison of two generations. J Allergy Clin Immunol 2006;117:154-159. (Pubitemid 43017153)
23. von Hertzen L, Haahtela T. Disconnection of man and the soil - reason for the asthma and atopy epidemic? J Allergy Clin Immunol 2006;117: 334-344.
24. Remes ST, Koskela HO, Iivanainen K, Pekkanen J. Allergen-specific sensitisation in asthma and allergic diseases in children: the study on farmers' and non-farmers' children. Clin Exp Allergy 2005;35: 160-166. (Pubitemid 40353777)
25. Braun-Fahrländer C, Riedler J, Herz U, Eder W, Waser M, Grize L, Maisch S, Carr D, Gerlach F, Bufe A, et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002;347:869-877.
26. Pekkarinen P, von Hertzen L, Laatikainen T, Mäkelä M, Jousilahti P, Kosunen TU, Pantelejev V, Vartiainen E, Haahtela T. Disparities in proportions of asthma, rhinitis and eczema associated with allergen specific IgE between Finnish and Russian Karelia. Allergy 2007;62: 281-287.
27. von Hertzen LC, Laatikainen T, Pennanen S, Mäkelä MJ. Haahtela T and the Karelian Allergy Study Group. Is house dust mite monosensitization associated with clinical disease? Allergy 2008;63:379-381.
28. Voor T. Microorganisms in infancy and development of allergy: comparison of Estonian and Swedish children [thesis]. Tartu, Estonia: Tartu University Press; 2005.
29. Weiland SK, von Mutius E, Hirsh T, Duhme H, Fritzsch C, Werner B, Husing A, Stender M, Renz H, Leupold W, et al. Prevalence of respiratory and atopic disorders among children in the East and West of Germany five years after unification. Eur Respir J 1999;14:862-870. (Pubitemid 29519350)
30. Hirsch TH, Range U, Walther KU, Hederer B, Lä ssig S, Frey G, Leupold W. Prevalence and determinants of house dust mite allergen in East German homes. Clin Exp Allergy 1998;28:956-964.
31. Zock JP, Heinrich J, Jarvis D, Verlato G, Norbäck D, Plana E, Sunyer J, Chinn S, Olivieri M, Soon A, et al. Distribution and determinants of house dust allergens in Europe: the European Community Respiratory Health Survey II. J Allergy Clin Immunol 2006;118:682-690. (Pubitemid 44301401)
32. Lau S, Illi S, Sommerfeld C, Niggemann B, Bergmann R, von Mutius E, Wahn U; Multicentre Allergy Study Group. Early exposure to housedust mite and cat allergens and development of childhood asthma: a cohort study. Lancet 2000;356:1392-1397. (Pubitemid 30800207)
33. Johnson CC, Ownby D, Havstad S, Peterson E. Family history, dust mite exposure in early childhood, and risk for pediatric atopy and asthma. J Allergy Clin Immunol 2004;114:105-110. (Pubitemid 39005124)
34. Carter PM, Peterson EL, Ownby DR, Zoratti EM, Johnson CC. Relationship of house-dust mite allergen exposure in children's bedrooms in infancy to bronchial hyperresponsiveness and asthma diagnosis by age 6 to 7. Ann Allergy Asthma Immunol 2003;90:41-44.
35. Brussee JE, Smit HA, van Strien RT, Corver K, Kerkhof M, Wijga AH, Aalberse RC, Postma D, Gerritsen J, Grobbee DE, et al. Allergen exposure in infancy and the development of sensitization, wheeze, and asthma at 4 years. J Allergy Clin Immunol 2005;115:946-952. (Pubitemid 40616207)
36. Polk S, Sunyer J, Muñoz-Ortiz L, Barnes M, Torrent M, Figueroa C, Harris J, Vall O, Antó JM, Cullinan P. A prospective study of Fel d1 and Der p1 exposure in infancy and childhood wheezing. Am J Respir Crit Care Med 2004;170:273-278. (Pubitemid 38971412)
37. Torrent M, Sunyer J, Garcia R, Harris J, Iturriaga MV, Puig C, Vall O, Anto JM, Newman Taylor AJ, Cullinan P. Early-life allergen exposure and atopy, asthma, and wheeze up to 6 years of age. Am J Respir Crit Care Med 2007;176:446-453. (Pubitemid 47358098)
38. Illi S, von Mutius E, Lau S, Niggemann B, Grüber C, Wahn U. Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study. Lancet 2006;368:763-770. (Pubitemid 44279054)
39. Custovic A, Simpson A. Environmental allergen exposure, sensitisation and asthma: from whole populations to individuals at risk. Thorax 2004;59:825-827. (Pubitemid 39389620)
40. Halmerbauer G, Gartner C, Schierl M, Arshad H, Dean T, Koller DY, Karmaus W, Kuehr J, Forster J, Urbanek R, et al. Study on the Prevention of Allergy in Children in Europe (SPACE): allergic sensitisation at 1 year of age in a controlled trial of allergen avoidance from birth. Pediatr Allergy Immunol 2003;14:10-17. (Pubitemid 36603984)
41. Peat JK, Mihrshahi S, Kemp AS, Marks GB, Tovey ER, Webb K, Mellis CM, Leeder SR. Three year outcomes of dietary fatty acid modification and house dust mite reduction in the Childhood Asthma Prevention Study (CAPS). J Allergy Clin Immunol 2004;114:807-813. (Pubitemid 39330250)
42. Becker A, Watson W, Ferguson A, Dimich-Ward H, Chang-Yeung M. The Canadian Asthma Primary Preventions Study: outcomes at 2 years of age. J Allergy Clin Immunol 2004;113:650-656. (Pubitemid 38530418)
43. Koopman LP, van Strien, Kerkhof M, Wijga A, Smit H, de Jongste J, Gerritsen J, Aalberse R, Brunekreef B, Neijens H; Prevention and Incidence of Asthma and Mite Allergy (PIAMA) Study. Placebo-controlled trial of house dust mite-impermeable mattress covers: effects on symptoms in early childhood. Am J Respir Crit Care Med 2002;166:307-313.
44. Arshad SH, Bateman B, Matthews SM. Primary prevention of asthma and atopy during childhood by allergen avoidance in infancy: a randomised controlled study. Thorax 2003;58:489-493. (Pubitemid 36714009)
45. Woodcock A, Lowe LA, Murray CS, Simpson BM, Pipis SD, Kissen P, Simpson A, Custovic A. Early life environmental control: effect on symptoms, sensitisation and lung function at age 3 years. Am J Respir Crit Care Med 2004;170:433-439. (Pubitemid 39214619)
46. Morgan W, Crain E, Gruchalla R, O'Connor G, Kattan M, Evans R, Stout J, Malindzak G, Smartt E, Plaut M, et al. Results of a home-based environmental intervention among urban children with asthma. N Engl J Med 2004;351:1068-1080. (Pubitemid 39167511)
47. van Schayck OCP, Maas T, Kaper J, Knottnerus AJ, Sheikh A. Is there any role for allergen avoidance in the primary prevention of childhood asthma? J Allergy Clin Immunol 2007;119:1323-1328.
48. O'Connor GT. Allergen avoidance in asthma: what do we do now? J Allergy Clin Immunol 2005;116:26-30.
49. Haahtela T, von Hertzen L, Mäkelä M, Hannuksela M; Finnish Allergy Programme Working Group. Finnish Allergy Programme 2008-2018: time to act and change the course. Allergy 2008;63:634-645.
50. Taylor A, Verhhagen J, Blaser K, Akdis M, Akdis CA. Mechanisms of immune suppression by interleukin-10 and transforming growth factor-b: the role of T regulatory cells. Immunology 2006;117: 433-442.
51. Jutel M, Akdis M, Budak F, Aebischer-Casaulta C, Wrzyszcz M, Blaser K, Akdis CA. IL-10 and TGF-b cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol 2003;33:1205-1214. (Pubitemid 36609138)
52. Akids M, Verhagen J, Taylor A, Karamloo F, Karagiannidis C, Crameri R, Thunberg S, Deniz G, Valenta R, Fiebig H, et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med 2004;199:1567-1575. (Pubitemid 38780411)
53. Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis. Cell 2004;118:229-241. (Pubitemid 38962578)
54. Taylor R, Richmond P, Upham J. Toll-like receptor 2 ligands inhibit Th2 responses to mite allergen. J Allergy Clin Immunol 2006;117: 1148-1154.
55. Wenzel SE. Asthma: defining of the persistent adult phenotypes. Lancet 2006;368:804-813.
56. Tovey ER, Almqvist C, Li Q, Grisafulli D, Marks GB. Nonlinear relationship of mite allergen exposure to mite sensitisation and asthma in a birth cohort. J Allergy Clin Immunol 2008;122:114-118. (Pubitemid 351899078)
57. van Velzen E, van den Bos JW, Benckhuijsen JA, van Essel T, de Bruijn R, Aalbers R. Effect of allergen avoidance at high altitude on direct and in direct bronchial hyperresponsiveness and markers of inflammation in children with allergic asthma. Thorax 1996;51:582-584. (Pubitemid 26226510)