Nonlinear relationship of mite allergen exposure to mite sensitization and asthma in a birth cohort

Journal of Allergy and Clinical Immunology

Volumn 122, Issue 1, 2008, Pages

  Tovey, Euan R ^a,b   Almqvist, Catarina ^a,b,c,d   Li, Qiang ^a,e   Crisafulli, Daniele ^a,b,c   Marks, Guy B ^a,b,c  

^a WOOLCOCK INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b University of Sydney   (Australia)

^c Cooperative Research Centre for Asthma ^*  (Australia)

^d KAROLINSKA INSTITUTE   (Sweden)

^e GEORGE INSTITUTE FOR INTERNATIONAL HEALTH   (Australia)

Author keywords

Allergens; asthma; childhood; Der p 1; high dose tolerance; house dust mite; sensitization

Indexed keywords

HOUSE DUST ALLERGEN;

ARTICLE; ASTHMA; ATOPY; CHILD; CHILDHOOD DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; DERMATOPHAGOIDES; ECZEMA; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOMES RESEARCH; PRIORITY JOURNAL; SENSITIZATION; SKIN TEST; WHEEZING;

EID: 46049102765     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2008.05.010     Document Type: Article

References (43)

1. Sporik R., Holgate S.T., Platts-Mills T.A.E., and Cogswell J.J. Exposure to house-dust mite allergen (Der p 1) and the development of asthma in childhood. N Engl J Med 323 (1990) 502-507
2. Torrent M., Sunyer J., Munoz L., Cullinan P., Iturriaga M.V., Figueroa C., et al. Early-life domestic aeroallergen exposure and IgE sensitization at age 4 years. J Allergy Clin Immunol 118 (2006) 742-748
3. Carter P.M., Peterson E.L., Ownby D.R., Zoratti E.M., and Johnson C.C. Relationship of house-dust mite allergen exposure in children's bedrooms in infancy to bronchial hyperresponsiveness and asthma diagnosis by age 6 to 7. Ann Allergy Asthma Immunol 90 (2003) 41-44
4. Lau S., Illi S., Sommerfeld C., Niggemann B., Bergmann R., von Mutius E., et al. Early exposure to house-dust mite and cat allergens and development of childhood asthma: a cohort study. Lancet 356 (2000) 1392-1397
5. Pearce N., Douwes J., and Beasley R. Is allergen exposure the major primary cause of asthma?. Thorax 55 (2000) 424-431
6. Perzanowski M., Ronmark E., Platts-Mills T., and Lundback B. Effect of cat and dog ownership on sensitization and development of asthma among preteenage children. Am J Respir Crit Care Med 166 (2002) 696-702
7. Custovic A., Hallam C., Simpson B., Craven M., Simpson A., and Woodcock A. Decreased prevalence of sensitization to cats with high exposure to cat allergen. J Allergy Clin Immunol 108 (2001) 537-539
8. Hesselmar B., Aberg N., Aberg B., Eriksson B., and Bjorksten B. Does early exposure to cat or dog protect against later allergy development?. Clin Exp Allergy 29 (1999) 611-617
9. Kuiper S., Muris J.W., Dompeling E., Kester A.D., Wesseling G., Knottnerus J.A., et al. Interactive effect of family history and environmental factors on respiratory tract-related morbidity in infancy. J Allergy Clin Immunol 120 (2007) 388-395
10. Celedon J., Milton D., Ramsey C., Litonjua A., Ryan L., Platts-Mills T., et al. Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood. J Allergy Clin Immunol 120 (2007) 144-149
11. Schram-Bijkerk D., Doekes G., Boeve M., Douwes J., Riedler J., Ublagger E., et al. Nonlinear relations between house dust mite allergen levels and mite sensitization in farm and nonfarm children. Allergy 61 (2006) 640-647
12. Torrent M., Sunyer J., Garcia R., Harris J., Iturriaga M., Puig C., et al. Early-life allergen exposure and atopy, asthma, and wheeze up to 6 years of age. Am J Respir Crit Care Med 176 (2007) 446-453
13. Johnson C.C., Ownby D.R., Havstad S.L., and Peterson E.L. Family history, dust mite exposure in early childhood, and risk for pediatric atopy and asthma. J Allergy Clin Immunol 114 (2004) 105-110
14. Kramer U., Lemmen C., Bartusel E., Link E., Ring J., and Behrendt H. Current eczema in children is related to Der f 1 exposure but not to Der p 1 exposure. Br J Dermatol 154 (2006) 99-105
15. Harris J.M., Williams H.C., White C., Moffat S., Mills P., Taylor A.J.N., et al. Early allergen exposure and atopic eczema. Br J Dermatol 156 (2007) 698-704
16. Williams H., and Flohr C. How epidemiology has challenged 3 prevailing concepts about atopic dermatitis. J Allergy Clin Immunol 118 (2006) 209-213
17. Marks G.B. Environmental factors and gene-environment interactions in the aetiology of asthma. Clin Exp Pharmacol Physiol 33 (2006) 285-289
18. Umetsu D. Revising the immunological theories of asthma and allergy. Lancet 365 (2005) 98-100
19. Anto J.M. The causes of asthma: the need to look at the data with different eyes. Allergy 59 (2004) 121-123
20. Holt P.G., Macaubas C., Stumbles P.A., and Sly P.D. The role of allergy in the development of asthma. Nature 402 (1999) B12-B17
21. Aalberse R.C., Nieuwenhuys E.J., Hey M., and Stapel S.O. "Horoscope effect" not only for seasonal but also for non-seasonal allergens. Clin Exp Allergy 22 (1992) 1003-1006
22. Crisafulli D., Almqvist C., Marks G., and Tovey E. Seasonal trends in house dust mite allergen in children's beds over a 7-year period. Allergy 62 (2007) 1394-1400
23. Platts-Mills T.A., Thomas W.R., Aalberse R.C., Vervloet D., and Chapman M.D. Dust mite allergens and asthma: report of a second international workshop. J Allergy Clin Immunol 89 (1992) 1046-1060
24. Mihrshahi S., Peat J.K., Marks G.B., Mellis C.M., Tovey E.R., Webb K., et al. Eighteen-month outcomes of house dust mite avoidance and dietary fatty acid modification in the Childhood Asthma Prevention Study (CAPS). J Allergy Clin Immunol 111 (2003) 162-168
25. Marks G.B., Mihrshahi S., Kemp A.S., Tovey E.R., Webb K., Almqvist C., et al. Prevention of asthma during the first 5 years of life: a randomized controlled trial. J Allergy Clin Immunol 118 (2006) 53-61
26. Tovey E.R., Marks G.B., Matthews M., Green W.F., and Woolcock A. Changes in mite allergen Der p I in house dust following spraying with a tannic acid/acaricide solution. Clin Exp Allergy 22 (1992) 67-74
27. Armitage P., and Berry G. Statistical methods in medical research. 3rd ed. (1994), Blackwell Scientific Publications, London
28. Simpson A., John S.L., Jury F., Niven R., Woodcock A., Ollier W.E.R., et al. Endotoxin exposure, CD14, and allergic disease-an interaction between genes and the environment. Am J Respir Crit Care Med 174 (2006) 386-392
29. Douwes J., van Strien R., Doekes G., Smit J., Kerkhof M., Gerritsen J., et al. Does early indoor microbial exposure reduce the risk of asthma? The Prevention and Incidence of Asthma and Mite Allergy birth cohort study. J Allergy Clin Immunol 117 (2006) 1067-1073
30. Burton O., and Zaccone P. The potential role of chitin in allergic reactions. Trends Immunol 28 (2007) 419-422
31. Reese T., Liang H., Tager A., Luster A., Van Rooijen N., Voehringer D., et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 447 (2007) 92-96
32. Ozdemir C., Yazi D., Aydogan M., Akkoc T., Bahceciler N., Strong P., et al. Treatment with chitin microparticles is protective against lung histopathology in a murine asthma model. Clin Exp Allergy 36 (2006) 960-968
33. Strong P., Clark H., and Reid K. Intranasal application of chitin microparticles down-regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine models of allergy. Clin Exp Allergy 32 (2002) 1794-1800
34. Platts-Mills T., Vaughan J., Squillace S., Woodfolk J., and Sporik R. Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study. Lancet 357 (2001) 752-756
35. Portengen L., de Meer G., Doekes G., and Heederik D. Immunoglobulin G4 antibodies to rat urinary allergens, sensitization and symptomatic allergy in laboratory animal workers. Clin Exp Allergy 34 (2004) 1243-1250
36. Jarvis D., Zock J.P., Heinrich J., Svanes C., Verlato G., Olivieri M., et al. Cat and dust mite allergen levels, specific IgG and IgG(4), and respiratory symptoms in adults. J Allergy Clin Immunol 119 (2007) 697-704
37. Brussee J.E., Smit H.A., van Strien R.T., Corver K., Kerkhof M., Wijga A.H., et al. Allergen exposure in infancy and the development of sensitization, wheeze, and asthma at 4 years. J Allergy Clin Immunol 115 (2005) 946-952
38. Almqvist C. High allergen exposure as a risk factor for asthma and allergic disease. Clin Rev Allergy Immunol 28 (2005) 25-41
39. Cullinan P., MacNeill S.J., Harris J.M., Moffat S., White C., Mills P., et al. Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study. Thorax 59 (2004) 855-861
40. Antens C.J.M., Oldenwening M., Wolse A., Gehring U., Smit H.A., Aalberse R.C., et al. Repeated measurements of mite and pet allergen levels in house dust over a time period of 8 years. Clin Exp Allergy 36 (2006) 1525-1531
41. Tovey E.R., O'Meara T.J., and Marks G.B. Bed covers and dust mites. [author reply]. N Engl J Med 349 (2003) 1668-1671
42. Gore R.B., Hadi E.A., Craven M., Smillie F.I., O'Meara T.J., Tovey E.R., et al. Personal exposure to house dust mite allergen in bed: nasal air sampling and reservoir allergen levels. Clin Exp Allergy 32 (2002) 856-859
43. Gore R.B., Curbishley L., Truman N., Hadley E., Woodcock A., Langley S.J., et al. Intranasal air sampling in homes: Relationships among reservoir allergen concentrations and asthma severity. J Allergy Clin Immunol 117 (2006) 649-655