Conformational effects of Lys191 in the human GnRH receptor: Mutagenesis and molecular dynamics simulations studies

Journal of Endocrinology

Volumn 201, Issue 2, 2009, Pages 297-307

  Jardón Valadez, Eduardo ^a,b   Aguilar Rojas, Arturo ^a   Maya Núñez, Guadalupe ^a   Leaños Miranda, Alfredo ^a   Piñeiro, Ángel ^b,c   Conn, P Michael ^a,d   Ulloa Aguirre, Alfredo ^a,d  

^a Hospital Luis Castelazo Ayala   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUSERELIN; CELL SURFACE RECEPTOR; CYSTEINE; GONADORELIN RECEPTOR; INOSITOL PHOSPHATE; LYSINE; MUTANT PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL SURFACE; COMPUTER MODEL; COMPUTER PREDICTION; CONTROLLED STUDY; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENE STRUCTURE; HYDROGEN BOND; INTRACELLULAR TRANSPORT; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; ONLINE SYSTEM; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR BINDING; SIMULATION; SITE DIRECTED MUTAGENESIS; ANIMAL; BINDING SITE; CELL STRAIN COS1; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; BINDING SITES; BUSERELIN; CERCOPITHECUS AETHIOPS; COMPUTER SIMULATION; COS CELLS; HUMANS; HYDROGEN BONDING; LYSINE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; PROTEIN CONFORMATION; PROTEIN TRANSPORT; RECEPTORS, LHRH;

EID: 67650711627     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-08-0527     Document Type: Article

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