메뉴 건너뛰기




Volumn 151, Issue 1-2, 1999, Pages 129-136

The tail of the gonadotrophin-releasing hormone receptor: Desensitization at, and distal to, G protein-coupled receptors

Author keywords

Ca2+; Desensitization; G protein coupled receptor; Gonadotrophin releasing hormone; Internalization

Indexed keywords

CALCIUM; GONADORELIN; GONADORELIN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; RETINA S ANTIGEN;

EID: 0033603021     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(99)00024-6     Document Type: Article
Times cited : (79)

References (63)
  • 1
    • 0028851942 scopus 로고
    • Rapid desensitization of GnRH-stimulated intracellular signalling events in αt3-1 and HEK-293 cells expressing the GnRH receptor
    • Anderson L., McGregor A., Cook J.V., Chilvers E., Eidne K.A. Rapid desensitization of GnRH-stimulated intracellular signalling events in αT3-1 and HEK-293 cells expressing the GnRH receptor. Endocrinology. 136:1995;5228-5231.
    • (1995) Endocrinology , vol.136 , pp. 5228-5231
    • Anderson, L.1    McGregor, A.2    Cook, J.V.3    Chilvers, E.4    Eidne, K.A.5
  • 2
    • 0026571589 scopus 로고
    • Clinical applications of GnRH and its analogues
    • Barbieri R.L. Clinical applications of GnRH and its analogues. Trends Endocrinol. Metab. 3:1992;30-34.
    • (1992) Trends Endocrinol. Metab. , vol.3 , pp. 30-34
    • Barbieri, R.L.1
  • 3
    • 0027397544 scopus 로고
    • Inositol trisphosphate and calcium signalling
    • Berridge M.J. Inositol trisphosphate and calcium signalling. Nature. 361:1993;315-325.
    • (1993) Nature , vol.361 , pp. 315-325
    • Berridge, M.J.1
  • 4
    • 0026694917 scopus 로고
    • Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiological regulator
    • Berstein G., Blank J.L., Jhon D.Y., Exton J.H., Rhee S.G., Ross E.M. Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiological regulator. Cell. 70:1992;411-418.
    • (1992) Cell , vol.70 , pp. 411-418
    • Berstein, G.1    Blank, J.L.2    Jhon, D.Y.3    Exton, J.H.4    Rhee, S.G.5    Ross, E.M.6
  • 5
    • 0030057466 scopus 로고    scopus 로고
    • Effects of extracellular nucleotides in the pituitary: ATP receptor-mediated responses in gonadotrope-derived αt3-1 cells
    • Chen Z-P., Kratzmeier M., Poch A., Xu S., McArdle C.A., Levy A., Mukhopadhyay A.K., Lightman S.L. Effects of extracellular nucleotides in the pituitary: ATP receptor-mediated responses in gonadotrope-derived αT3-1 cells. Endocrinology. 137:1996;248-256.
    • (1996) Endocrinology , vol.137 , pp. 248-256
    • Chen, Z.-P.1    Kratzmeier, M.2    Poch, A.3    Xu, S.4    McArdle, C.A.5    Levy, A.6    Mukhopadhyay, A.K.7    Lightman, S.L.8
  • 6
    • 0001711846 scopus 로고
    • E.Y. Adashi, J.A. Rock, & Z. Rosenwaks. Philadelphia: Lippincott-Raven Publishers
    • Conn P.M. Adashi E.Y., Rock J.A., Rosenwaks Z. Reproductive Endocrinology, Surgery and Technology Vol 1. 1995;163-179 Lippincott-Raven Publishers, Philadelphia.
    • (1995) Reproductive Endocrinology, Surgery and Technology Vol 1 , pp. 163-179
    • Conn, P.M.1
  • 7
    • 0023065848 scopus 로고
    • The molecular mechanism of action of gonadotrophin releasing hormone (GnRH) in the pituitary
    • Conn P.M., Huckle W.R., Andrews W.V., McArdle C.A. The molecular mechanism of action of gonadotrophin releasing hormone (GnRH) in the pituitary. Rec. Prog. Horm. Res. 43:1987;29-68.
    • (1987) Rec. Prog. Horm. Res. , vol.43 , pp. 29-68
    • Conn, P.M.1    Huckle, W.R.2    Andrews, W.V.3    McArdle, C.A.4
  • 8
    • 0028242680 scopus 로고
    • Absence of rapid desensitization of the mouse gonadotrophin-releasing hormone receptor
    • Davidson J.S., Wakefield I.K., Millar R.P. Absence of rapid desensitization of the mouse gonadotrophin-releasing hormone receptor. Biochem. J. 300:1994;299-302.
    • (1994) Biochem. J. , vol.300 , pp. 299-302
    • Davidson, J.S.1    Wakefield, I.K.2    Millar, R.P.3
  • 9
    • 0018172678 scopus 로고
    • Refractoriness of the pituitary gland after continuous exposure to luteinizing hormone releasing hormone
    • Dekoning J., van Dieten J.A.M.J., van Rees G.P. Refractoriness of the pituitary gland after continuous exposure to luteinizing hormone releasing hormone. J. Endocrinol. 79:1978;311-318.
    • (1978) J. Endocrinol. , vol.79 , pp. 311-318
    • Dekoning, J.1    Van Dieten, J.A.M.J.2    Van Rees, G.P.3
  • 10
  • 11
    • 0030890736 scopus 로고    scopus 로고
    • Oxytocin receptor-mediated activation of phosphoinositidase C and elevation of cytosolic calcium in the gonadotrope-derived αt3-1 cell line
    • Evans J.J., Forrest-Owen W., McArdle C.A. Oxytocin receptor-mediated activation of phosphoinositidase C and elevation of cytosolic calcium in the gonadotrope-derived αT3-1 cell line. Endocrinology. 138:1997;2049-2055.
    • (1997) Endocrinology , vol.138 , pp. 2049-2055
    • Evans, J.J.1    Forrest-Owen, W.2    McArdle, C.A.3
  • 12
    • 0030593035 scopus 로고    scopus 로고
    • Role of β-arrestin in mediating agonist-promoted G-protein-coupled receptor internalization
    • Ferguson S.S.G., Downey W.E., Colapietro A-M., Barak L.S., Menard L., Caron M.G. Role of β-arrestin in mediating agonist-promoted G-protein-coupled receptor internalization. Science. 271:1997;363-366.
    • (1997) Science , vol.271 , pp. 363-366
    • Ferguson, S.S.G.1    Downey, W.E.2    Colapietro, A.-M.3    Barak, L.S.4    Menard, L.5    Caron, M.G.6
  • 13
    • 0345692107 scopus 로고    scopus 로고
    • The lack of gonadotrophin-releasing hormone receptor desensitization in αt3-1 cells is not because of GnRh receptor reserve or phosphatidylinositol 4,5 bis-phosphate pool size
    • 'in press'
    • Forrest-Owen, W., Willars, G.B., Nahorski, S.R., Assefa, D., Davidson, J.S., Hislop, J., McArdle, C.A., 1998. The lack of gonadotrophin-releasing hormone receptor desensitization in αT3-1 cells is not because of GnRh receptor reserve or phosphatidylinositol 4,5 bis-phosphate pool size, Mol. Cell. Endocrinol. 'in press'.
    • (1998) Mol. Cell. Endocrinol.
    • Forrest-Owen, W.1    Willars, G.B.2    Nahorski, S.R.3    Assefa, D.4    Davidson, J.S.5    Hislop, J.6    McArdle, C.A.7
  • 14
    • 0023567023 scopus 로고
    • Relative roles of calcium derived from intra- And extracellular sources in dynamic LH release from perifused pituitary cells
    • Hansen J.R., McArdle C.A., Conn P.M. Relative roles of calcium derived from intra- and extracellular sources in dynamic LH release from perifused pituitary cells. Mol. Endocrinol. 1:1987;808-815.
    • (1987) Mol. Endocrinol. , vol.1 , pp. 808-815
    • Hansen, J.R.1    McArdle, C.A.2    Conn, P.M.3
  • 15
    • 0032496280 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics
    • Heding A., Vrecl M., Bogerd J. et al. Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics. J. Biol. Chem. 273:1998a;11472-11477.
    • (1998) J. Biol. Chem. , vol.273 , pp. 11472-11477
    • Heding, A.1    Vrecl, M.2    Bogerd, J.3
  • 17
    • 0029196026 scopus 로고
    • Signalling mechanisms during the response of pituitary gonadotrophs to GnRH
    • Hille B., Tse A., Tse F.W., Bosma M.M. Signalling mechanisms during the response of pituitary gonadotrophs to GnRH. Rec. Prog. Horm. Res. 50:1995;75-95.
    • (1995) Rec. Prog. Horm. Res. , vol.50 , pp. 75-95
    • Hille, B.1    Tse, A.2    Tse, F.W.3    Bosma, M.M.4
  • 19
    • 0022309329 scopus 로고
    • GnRH-stimulated LH release from pituitary cells in culture: Refractoriness and recovery
    • Jinnah H.A., Conn P.M. GnRH-stimulated LH release from pituitary cells in culture: refractoriness and recovery. Am. J. Physiol. (Endocrinol. Metab.). 249:1985;E619-625.
    • (1985) Am. J. Physiol. (Endocrinol. Metab.) , vol.249 , pp. 619-625
    • Jinnah, H.A.1    Conn, P.M.2
  • 20
    • 0022532629 scopus 로고
    • GnRH-mediated desensitization of cultured rat anterior pituitary cells can be uncoupled from LH release
    • Jinnah H.A., Conn P.M. GnRH-mediated desensitization of cultured rat anterior pituitary cells can be uncoupled from LH release. Endocrinology. 118:1986;2599-2604.
    • (1986) Endocrinology , vol.118 , pp. 2599-2604
    • Jinnah, H.A.1    Conn, P.M.2
  • 21
    • 0031038565 scopus 로고    scopus 로고
    • Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines
    • Kaiser U.B., Conn P.M., Chin W.W. Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines. Endocrin. Rev. 18:1997;46-70.
    • (1997) Endocrin. Rev. , vol.18 , pp. 46-70
    • Kaiser, U.B.1    Conn, P.M.2    Chin, W.W.3
  • 22
    • 0027051673 scopus 로고
    • Rat gonadotrophin-releasing hormone (GnRH) receptor: Tissue expression and hormonal regulation of its mRNA
    • Kakar S.S., Musgrove L.C., Devor D.C., Sellers J.C., Neill J.D. Rat gonadotrophin-releasing hormone (GnRH) receptor: tissue expression and hormonal regulation of its mRNA. Biochem. Biophys. Res. Commun. 189:1992;289-295.
    • (1992) Biochem. Biophys. Res. Commun. , vol.189 , pp. 289-295
    • Kakar, S.S.1    Musgrove, L.C.2    Devor, D.C.3    Sellers, J.C.4    Neill, J.D.5
  • 23
    • 0030907376 scopus 로고    scopus 로고
    • A new family of G-protein regulators-the RGS proteins
    • Koelle M.R. A new family of G-protein regulators-the RGS proteins. Curr. Opin. Cell. Biol. 9:1997;143-147.
    • (1997) Curr. Opin. Cell. Biol. , vol.9 , pp. 143-147
    • Koelle, M.R.1
  • 24
    • 0031036520 scopus 로고    scopus 로고
    • The role of sequestration in G-protein coupled receptor resensitization
    • Krueger K.M., Daaka Y., Pitcher J.A., Lefkowitz R.B. The role of sequestration in G-protein coupled receptor resensitization. J. Biol. Chem. 272:1997;5-8.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5-8
    • Krueger, K.M.1    Daaka, Y.2    Pitcher, J.A.3    Lefkowitz, R.B.4
  • 25
    • 0027155189 scopus 로고
    • The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2
    • Kwatra M.M., Schwinn D.A., Schreurs J. et al. The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2. J. Biol. Chem. 268:1993;9161-9164.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9161-9164
    • Kwatra, M.M.1    Schwinn, D.A.2    Schreurs, J.3
  • 27
    • 0025350916 scopus 로고
    • Role of phosphorylation in desensitization of the β-adrenoceptor
    • Lefkowitz R.J., Hausdorff W.P., Caron M.G. Role of phosphorylation in desensitization of the β-adrenoceptor. Trends Pharmacol. Sci. 11:1990;190-194.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 190-194
    • Lefkowitz, R.J.1    Hausdorff, W.P.2    Caron, M.G.3
  • 29
    • 0031447091 scopus 로고    scopus 로고
    • Pituitary adenylyl cyclase-activating polypeptide (PACAP) actions on αt3-1 gonadotrophs show desensitization
    • McArdle C.A., Forrest-Owen W. Pituitary adenylyl cyclase-activating polypeptide (PACAP) actions on αT3-1 gonadotrophs show desensitization. J. Neuroendocrinol. 9:1998;893-901.
    • (1998) J. Neuroendocrinol. , vol.9 , pp. 893-901
    • McArdle, C.A.1    Forrest-Owen, W.2
  • 31
    • 0028862330 scopus 로고
    • Desensitization of gonadotropin-releasing hormone action in the gonadotrope-derived αt3-1 cell line
    • McArdle C.A., Forrest-Owen W., Willars G., Davidson J., Poch A., Kratzmeier M. Desensitization of gonadotropin-releasing hormone action in the gonadotrope-derived αT3-1 cell line. Endocrinology. 136:1995;4864-4871.
    • (1995) Endocrinology , vol.136 , pp. 4864-4871
    • McArdle, C.A.1    Forrest-Owen, W.2    Willars, G.3    Davidson, J.4    Poch, A.5    Kratzmeier, M.6
  • 32
    • 0023641189 scopus 로고
    • Homologous down-regulation of gonadotrophin releasing hormone receptors and de-sensitization of gonadotropes: Lack of dependence on protein kinase C
    • McArdle C.A., Gorospe W.C., Huckle W.R., Conn P.M. Homologous down-regulation of gonadotrophin releasing hormone receptors and de-sensitization of gonadotropes: lack of dependence on protein kinase C. Mol. Endocrinol. 1:1987;420-429.
    • (1987) Mol. Endocrinol. , vol.1 , pp. 420-429
    • McArdle, C.A.1    Gorospe, W.C.2    Huckle, W.R.3    Conn, P.M.4
  • 33
    • 0023904772 scopus 로고
    • Enhanced responsiveness of gonadotropes following protein kinase C activation: Post receptor regulation of gonadotrophin releasing hormone action
    • McArdle C.A., Huckle W.R., Johnson L., Conn P.M. Enhanced responsiveness of gonadotropes following protein kinase C activation: post receptor regulation of gonadotrophin releasing hormone action. Endocrinology. 122:1988;1905-1914.
    • (1988) Endocrinology , vol.122 , pp. 1905-1914
    • McArdle, C.A.1    Huckle, W.R.2    Johnson, L.3    Conn, P.M.4
  • 34
    • 0026684041 scopus 로고
    • 2+ pools is revealed by desensitization and by thapsigargin blockade
    • 2+ pools is revealed by desensitization and by thapsigargin blockade. Endocrinology. 130:1992;3567-3574.
    • (1992) Endocrinology , vol.130 , pp. 3567-3574
    • McArdle, C.A.1    Poch, A.2
  • 37
    • 0032568416 scopus 로고    scopus 로고
    • Rhodopsin-family receptors associate with small G proteins to activate phospholipase D
    • Mitchell R., McCulloch D., Lutz E. et al. Rhodopsin-family receptors associate with small G proteins to activate phospholipase D. Nature 6674. 392:1998;411-414.
    • (1998) Nature 6674 , vol.392 , pp. 411-414
    • Mitchell, R.1    McCulloch, D.2    Lutz, E.3
  • 38
    • 0032566523 scopus 로고    scopus 로고
    • Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor
    • Murray S.R., Evans C.J., von Zastrow M. Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor. J. Biol. Chem. 273:1998;24987-24991.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24987-24991
    • Murray, S.R.1    Evans, C.J.2    Von Zastrow, M.3
  • 39
    • 0031734588 scopus 로고    scopus 로고
    • Potential regulatory roles for G-protein receptor kinases and beta-arrestins in gonadotropin-releasing hormone receptor signalling
    • Neill J.D., Duck W., Musgrove L.C., Sellers J.C. Potential regulatory roles for G-protein receptor kinases and beta-arrestins in gonadotropin-releasing hormone receptor signalling. Endocrinology. 139:1998;1781-1788.
    • (1998) Endocrinology , vol.139 , pp. 1781-1788
    • Neill, J.D.1    Duck, W.2    Musgrove, L.C.3    Sellers, J.C.4
  • 40
    • 0031053536 scopus 로고    scopus 로고
    • Potential role for regulator of G-protein signalling (RGS3) in gonadotropin-releasing hormone (GnRH)-stimulated desensitization
    • Neill J.D., Duck W., Sellers J.C., Musgrove L.C., Scheschonka A., Druey K.M., Kehrl J.H. Potential role for regulator of G-protein signalling (RGS3) in gonadotropin-releasing hormone (GnRH)-stimulated desensitization. Endocrinology. 138:1997a;843-846.
    • (1997) Endocrinology , vol.138 , pp. 843-846
    • Neill, J.D.1    Duck, W.2    Sellers, J.C.3    Musgrove, L.C.4    Scheschonka, A.5    Druey, K.M.6    Kehrl, J.H.7
  • 41
    • 0029815762 scopus 로고    scopus 로고
    • Identification by polymerase chain reaction of the G-protein-coupled receptor kinases expressed in the mouse gonadotropic αt3-1 cell line
    • Neill J.D., Musgrove L.C., Sellers J.C., Duck L.W. Identification by polymerase chain reaction of the G-protein-coupled receptor kinases expressed in the mouse gonadotropic αT3-1 cell line. Endocrinology. 137:1996;3942-3947.
    • (1996) Endocrinology , vol.137 , pp. 3942-3947
    • Neill, J.D.1    Musgrove, L.C.2    Sellers, J.C.3    Duck, L.W.4
  • 42
    • 0030993419 scopus 로고    scopus 로고
    • Epitope-tagged gonadotropin-releasing hormone receptors heterologously expressed in mammalian (COS-1) and insect (Sf9) cells
    • Neill J.D., Sellers J.C., Musgrove L.C., Duck L.W. Epitope-tagged gonadotropin-releasing hormone receptors heterologously expressed in mammalian (COS-1) and insect (Sf9) cells. Mol. Cell. Endocrinol. 127:1997b;143-154.
    • (1997) Mol. Cell. Endocrinol. , vol.127 , pp. 143-154
    • Neill, J.D.1    Sellers, J.C.2    Musgrove, L.C.3    Duck, L.W.4
  • 43
    • 0031936827 scopus 로고    scopus 로고
    • Contrasting internalization kinetics of human and chicken gonadotropin-releasing hormone receptors mediated by C-terminal tail
    • Pawson A., Katz A., Sun Y-M., Lopes J., Illing N., Millar R.P., Davidson J.S. Contrasting internalization kinetics of human and chicken gonadotropin-releasing hormone receptors mediated by C-terminal tail. J. Endocrinol. 196:1998;R9-R12.
    • (1998) J. Endocrinol. , vol.196
    • Pawson, A.1    Katz, A.2    Sun, Y.-M.3    Lopes, J.4    Illing, N.5    Millar, R.P.6    Davidson, J.S.7
  • 44
    • 0030937284 scopus 로고    scopus 로고
    • Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor
    • Sealfon S.S., Weinstein H., Millar R.P. Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor. Endocrin. Rev. 18:1997;180-205.
    • (1997) Endocrin. Rev. , vol.18 , pp. 180-205
    • Sealfon, S.S.1    Weinstein, H.2    Millar, R.P.3
  • 46
    • 0029183393 scopus 로고
    • Expression and signal-transduction pathways of gonadotropin-releasing hormone receptors
    • Stojilkovic S.S., Catt K.J. Expression and signal-transduction pathways of gonadotropin-releasing hormone receptors. Rec. Prog. Horm. Res. 50:1995;161-205.
    • (1995) Rec. Prog. Horm. Res. , vol.50 , pp. 161-205
    • Stojilkovic, S.S.1    Catt, K.J.2
  • 47
    • 0024382515 scopus 로고
    • Desensitization of pituitary gonadotrophin secretion by agonist-induced inactivation of voltage-sensitive calcium channels
    • Stojilkovic S.S., Rojas E., Stutzin A., Izumi S., Catt K.J. Desensitization of pituitary gonadotrophin secretion by agonist-induced inactivation of voltage-sensitive calcium channels. J. Biol. Chem. 264:1989;10939-10940.
    • (1989) J. Biol. Chem. , vol.264 , pp. 10939-10940
    • Stojilkovic, S.S.1    Rojas, E.2    Stutzin, A.3    Izumi, S.4    Catt, K.J.5
  • 48
    • 0028092770 scopus 로고
    • Gonadotropin-releasing hormone receptors: Structure and signal-transduction pathways
    • Stojilkovic S.S., Reinhart J., Catt K.J. Gonadotropin-releasing hormone receptors: structure and signal-transduction pathways. Endocrine Rev. 15:1994;462-499.
    • (1994) Endocrine Rev. , vol.15 , pp. 462-499
    • Stojilkovic, S.S.1    Reinhart, J.2    Catt, K.J.3
  • 52
    • 0027278632 scopus 로고
    • 3-muscarinic receptors revealed by immunoprecipitation
    • 3-muscarinic receptors revealed by immunoprecipitation. J. Biol. Chem. 268:1993;9817-9823.
    • (1993) J. Biol. Chem. , vol.268 , pp. 9817-9823
    • Tobin, A.B.1    Nahorski, S.R.2
  • 53
    • 0030716407 scopus 로고    scopus 로고
    • Phosphorylation of phospholipase C-coupled receptors
    • Tobin A.B. Phosphorylation of phospholipase C-coupled receptors. Pharmacol. Ther. 75:1998;135-151.
    • (1998) Pharmacol. Ther. , vol.75 , pp. 135-151
    • Tobin, A.B.1
  • 54
    • 0030614827 scopus 로고    scopus 로고
    • 2+ release from internal stores controls exocytosis in pituitary gonadotrophs
    • 2+ release from internal stores controls exocytosis in pituitary gonadotrophs. Neuron. 18:1997;121-132.
    • (1997) Neuron , vol.18 , pp. 121-132
    • Tse, F.W.1    Tse, A.2    Hille, B.3    Horstmann, H.4    Almers, W.5
  • 55
    • 0026645598 scopus 로고
    • Cloning and functional expression of a mouse gonadotrophin-releasing hormone receptor
    • Tsutsumi M., Zhou W., Millar R.P. et al. Cloning and functional expression of a mouse gonadotrophin-releasing hormone receptor. Mol. Endocrinol. 6:1992;1163-1169.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1163-1169
    • Tsutsumi, M.1    Zhou, W.2    Millar, R.P.3
  • 58
    • 0028877801 scopus 로고
    • Homologous desensitization of gonadotrophin-releasing hormone (GnRH) secretion in vitro occurs within the duration of an endogenous GnRH pulse
    • Weiss J, Cote C.R., Jameson L., Crowley W.F.-Jr Homologous desensitization of gonadotrophin-releasing hormone (GnRH) secretion in vitro occurs within the duration of an endogenous GnRH pulse. Endocrinology. 136:1995;138-143.
    • (1995) Endocrinology , vol.136 , pp. 138-143
    • Weiss, J.1    Cote, C.R.2    Jameson, L.3    Crowley, W.F.-J.4
  • 59
    • 0032527736 scopus 로고    scopus 로고
    • 3 receptor, but not gonadotropin-releasing hormone receptor co-expressed in αt3-1 cells: Implications for mechanisms of rapid desensitization
    • 3 receptor, but not gonadotropin-releasing hormone receptor co-expressed in αT3-1 cells: implications for mechanisms of rapid desensitization. Biochem. J. 333:1998a;301-308.
    • (1998) Biochem. J. , vol.333 , pp. 301-308
    • Willars, G.B.1    McArdle, C.A.2    Nahorski, S.R.3
  • 60
    • 0006321904 scopus 로고    scopus 로고
    • Absence of rapid desensitization and agonist-dependent phosphorylation of the mammalian gonadotropin-releasing hormone receptor (GnRH-R) is associated with the absence of a cytoplasmic C-terminal tail
    • (abstract)
    • Willars, G.B., Nahorski, S.R., Eidne, K.A., Heding, A., 1998b. Absence of rapid desensitization and agonist-dependent phosphorylation of the mammalian gonadotropin-releasing hormone receptor (GnRH-R) is associated with the absence of a cytoplasmic C-terminal tail, Biochem. Soc. Trans. P13 (abstract).
    • (1998) Biochem. Soc. Trans. , vol.P13
    • Willars, G.B.1    Nahorski, S.R.2    Eidne, K.A.3    Heding, A.4
  • 61
    • 0025248506 scopus 로고
    • Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice
    • Windle J.J., Weiner R.I., Mellon P.L. Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice. Mol. Endocrinol. 4:1990;597-603.
    • (1990) Mol. Endocrinol. , vol.4 , pp. 597-603
    • Windle, J.J.1    Weiner, R.I.2    Mellon, P.L.3
  • 62
    • 0025837323 scopus 로고
    • 2+ mobilization and inositol 1,4,5-trisphosphate binding
    • 2+ mobilization and inositol 1,4,5-trisphosphate binding. J. Biol. Chem. 266:1991;22234-22241.
    • (1991) J. Biol. Chem. , vol.266 , pp. 22234-22241
    • Wojcikiewicz, R.J.H.1    Nahorski, S.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.