Application of the chiral base desymmetrisation of imides to the synthesis of the alkaloid jamtine and the antidepressant paroxetine

Tetrahedron

Volumn 59, Issue 46, 2003, Pages 9213-9230

  Gill, Christopher D ^a   Greenhalgh, Daniel A ^a   Simpkins, Nigel S ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Asymmetric synthesis; Chiral lithium amide base; Enantioselective enolisation; Imides; Jamtine; Paroxetine

Indexed keywords

1 BENZYL 4 (4 FLUOROPHENYL) 3 METHYLSULFONATEPIPERIDINE; 1 BENZYL 4 (4 FLUOROPHENYL) 3 PIPERIDINE METHANOL; 1 BENZYL 4 (4 FLUOROPHENYL) 3 [3,4 (METHYLENEDIOXY)PHENOXYMETHYL]PIPERIDINE; ALKALOID; ANTIDEPRESSANT AGENT; CYCLOHEXANE; IMIDE; LITHIUM DERIVATIVE; OXIDE; PAROXETINE; SUCCINIMIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHIRALITY; DRUG SYNTHESIS; ENANTIOSELECTIVITY; PRIORITY JOURNAL;

EID: 0142196124     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2003.08.046     Document Type: Article

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