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Volumn 65, Issue 1, 2009, Pages 98-106

The carboxyl-terminal domain of the heavy chain of tetanus toxin prevents dopaminergic degeneration and improves motor behavior in rats with striatal MPP+-lesions

Author keywords

Dopamine; Fine motor skills; Motor asymmetry; Neuroprotection; Striatum

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 3 O METHYLDOPAMINE; 3,4 DIHYDROXYPHENYLACETIC ACID; HOMOVANILLIC ACID; TETANUS TOXIN;

EID: 67650502218     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2009.06.001     Document Type: Article
Times cited : (32)

References (45)
  • 1
    • 0027452902 scopus 로고
    • Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: effects on drug-induced behaviours and skilled paw-reaching
    • Abrous D.N., Shaltot A.R.A., Torres E.M., and Dunnet S.B. Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: effects on drug-induced behaviours and skilled paw-reaching. Neuroscience 43 1 (1993) 187-193
    • (1993) Neuroscience , vol.43 , Issue.1 , pp. 187-193
    • Abrous, D.N.1    Shaltot, A.R.A.2    Torres, E.M.3    Dunnet, S.B.4
  • 3
    • 68849129297 scopus 로고    scopus 로고
    • Caleo, M., Schiavo, G., 2009. Central effects of tetanus and botulinum neurotoxins. Toxicon, doi:10.1016/j.toxicon.2008.12.026.
    • Caleo, M., Schiavo, G., 2009. Central effects of tetanus and botulinum neurotoxins. Toxicon, doi:10.1016/j.toxicon.2008.12.026.
  • 4
    • 58149461546 scopus 로고    scopus 로고
    • Fusion of the tetanus toxin C fragment binding domain and Bcl-xL for protection of peripheral nerve neurons
    • Carlton E., Teng Q., Federici T., Yang J., Riley J., and Boulis N.M. Fusion of the tetanus toxin C fragment binding domain and Bcl-xL for protection of peripheral nerve neurons. Neurosurgery 63 6 (2008) 1175-1184
    • (2008) Neurosurgery , vol.63 , Issue.6 , pp. 1175-1184
    • Carlton, E.1    Teng, Q.2    Federici, T.3    Yang, J.4    Riley, J.5    Boulis, N.M.6
  • 5
    • 4444360288 scopus 로고    scopus 로고
    • The C-terminal domain of the heavy chain of tetanus toxin rescues cerebellar granule neurons from apoptotic death: involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways
    • Chaïb-Oukadour I., Gil C., and Aguilera J. The C-terminal domain of the heavy chain of tetanus toxin rescues cerebellar granule neurons from apoptotic death: involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. J. Neurochem. 90 5 (2004) 1227-1236
    • (2004) J. Neurochem. , vol.90 , Issue.5 , pp. 1227-1236
    • Chaïb-Oukadour, I.1    Gil, C.2    Aguilera, J.3
  • 8
    • 0141788689 scopus 로고    scopus 로고
    • Protective effects of intracerebral adenoviral-mediated GDNF gene transfer in a rat model of Parkinson's disease
    • Chen X., Liu W., Guoyuan Y., Liu Z., Smith S., Calne D.B., and Chen S. Protective effects of intracerebral adenoviral-mediated GDNF gene transfer in a rat model of Parkinson's disease. Parkinsonism Relat. Disord. 10 1 (2003) 1-7
    • (2003) Parkinsonism Relat. Disord. , vol.10 , Issue.1 , pp. 1-7
    • Chen, X.1    Liu, W.2    Guoyuan, Y.3    Liu, Z.4    Smith, S.5    Calne, D.B.6    Chen, S.7
  • 9
    • 0345669747 scopus 로고    scopus 로고
    • Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF
    • Cohen A.D., Tillerson J.L., Smith A.D., Schallert T., and Zigmond M.J. Neuroprotective effects of prior limb use in 6-hydroxydopamine-treated rats: possible role of GDNF. J. Neurochem. 85 (2003) 299-305
    • (2003) J. Neurochem. , vol.85 , pp. 299-305
    • Cohen, A.D.1    Tillerson, J.L.2    Smith, A.D.3    Schallert, T.4    Zigmond, M.J.5
  • 10
    • 5644293405 scopus 로고    scopus 로고
    • Evaluation of animal models of Parkinson's disease for neuroprotective strategies
    • Emborg M.E. Evaluation of animal models of Parkinson's disease for neuroprotective strategies. J. Neurosci. Methods 139 (2004) 121-143
    • (2004) J. Neurosci. Methods , vol.139 , pp. 121-143
    • Emborg, M.E.1
  • 11
    • 0034708794 scopus 로고    scopus 로고
    • The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding
    • Emsley P., Fotinou C., Black I., Fairweather N.F., Charles I.G., Watts C., Hewitt E., and Isaacs N.W. The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J. Biol. Chem. 275 (2000) 8889-8894
    • (2000) J. Biol. Chem. , vol.275 , pp. 8889-8894
    • Emsley, P.1    Fotinou, C.2    Black, I.3    Fairweather, N.F.4    Charles, I.G.5    Watts, C.6    Hewitt, E.7    Isaacs, N.W.8
  • 14
    • 0034944536 scopus 로고    scopus 로고
    • Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat
    • Galvan A., Floran B., Erlij D., and Aceves J. Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat. J. Neural. Transm. 108 2 (2001) 153-166
    • (2001) J. Neural. Transm. , vol.108 , Issue.2 , pp. 153-166
    • Galvan, A.1    Floran, B.2    Erlij, D.3    Aceves, J.4
  • 15
    • 0037146648 scopus 로고    scopus 로고
    • A 'single toxin-double lesion' rat model of striatonigral degeneration by intrastriatal 1-methyl-4-phenylpyridinium ion injection: a motor behavioural analysis
    • Ghorayeb I., Fernagut P.O., Hervier L., Labattu B., Bioulac B., and Tison F. A 'single toxin-double lesion' rat model of striatonigral degeneration by intrastriatal 1-methyl-4-phenylpyridinium ion injection: a motor behavioural analysis. Neuroscience 115 2 (2002) 533-546
    • (2002) Neuroscience , vol.115 , Issue.2 , pp. 533-546
    • Ghorayeb, I.1    Fernagut, P.O.2    Hervier, L.3    Labattu, B.4    Bioulac, B.5    Tison, F.6
  • 16
    • 0041963051 scopus 로고    scopus 로고
    • C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signaling pathways in a Trk receptor-dependent manner in cultured cortical neurons
    • Gil C., Chaib-oukadour I., and Aguilera J. C-terminal fragment of tetanus toxin heavy chain activates Akt and MEK/ERK signaling pathways in a Trk receptor-dependent manner in cultured cortical neurons. J. Neurochem. 373 (2003) 613-620
    • (2003) J. Neurochem. , vol.373 , pp. 613-620
    • Gil, C.1    Chaib-oukadour, I.2    Aguilera, J.3
  • 17
    • 0035872218 scopus 로고    scopus 로고
    • HC fragment (C-terminal portion of the heavy chain) of tetanus toxin activates protein kinase C isoforms and phosphoproteins involved in signal transduction
    • Gil C., Chaib-Oukadour I., Blasi J., and Aguilera J. HC fragment (C-terminal portion of the heavy chain) of tetanus toxin activates protein kinase C isoforms and phosphoproteins involved in signal transduction. J. Biochem. 356 1 (2001) 97-103
    • (2001) J. Biochem. , vol.356 , Issue.1 , pp. 97-103
    • Gil, C.1    Chaib-Oukadour, I.2    Blasi, J.3    Aguilera, J.4
  • 18
    • 0032809423 scopus 로고    scopus 로고
    • Differential action of nerve growth factor and phorbol ester TPA on rat synaptosomal PKC isoenzymes
    • Gil C., Pelliccioni P., Itarte E., and Aguilera J. Differential action of nerve growth factor and phorbol ester TPA on rat synaptosomal PKC isoenzymes. Neurochem. Int. 35 4 (1999) 281-291
    • (1999) Neurochem. Int. , vol.35 , Issue.4 , pp. 281-291
    • Gil, C.1    Pelliccioni, P.2    Itarte, E.3    Aguilera, J.4
  • 19
    • 0021224694 scopus 로고
    • Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidase inhibitors
    • Heikkila R.E., Manzino L., Cabbat F.S., and Duvoisin R.C. Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidase inhibitors. Nature 311 (1984) 467-469
    • (1984) Nature , vol.311 , pp. 467-469
    • Heikkila, R.E.1    Manzino, L.2    Cabbat, F.S.3    Duvoisin, R.C.4
  • 20
    • 0022403289 scopus 로고
    • Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity
    • Heikkila R.E., Nicklas W.J., Vyas I., and Duvoisin R.C. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. Neurosci. Lett. 62 3 (1985) 389-394
    • (1985) Neurosci. Lett. , vol.62 , Issue.3 , pp. 389-394
    • Heikkila, R.E.1    Nicklas, W.J.2    Vyas, I.3    Duvoisin, R.C.4
  • 21
    • 0034177056 scopus 로고    scopus 로고
    • C-terminal half of tetanus toxin fragment C is sufficient for neuronal binding and interaction with a putative protein receptor
    • Herreros J., Lalli G., and Schiavo G. C-terminal half of tetanus toxin fragment C is sufficient for neuronal binding and interaction with a putative protein receptor. Biochem. J. 347 (2000) 199-204
    • (2000) Biochem. J. , vol.347 , pp. 199-204
    • Herreros, J.1    Lalli, G.2    Schiavo, G.3
  • 22
    • 0028874203 scopus 로고
    • GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo
    • Kearns C.M., and Gash D.M. GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo. Brain Res. 672 (1995) 104-111
    • (1995) Brain Res. , vol.672 , pp. 104-111
    • Kearns, C.M.1    Gash, D.M.2
  • 23
    • 1642499508 scopus 로고    scopus 로고
    • Localized striatal delivery of GDNF as a treatment for Parkinson disease
    • Kirik D., Georgievska B., and Björklund A. Localized striatal delivery of GDNF as a treatment for Parkinson disease. Nat. Neurosci. 7 2 (2004) 105-110
    • (2004) Nat. Neurosci. , vol.7 , Issue.2 , pp. 105-110
    • Kirik, D.1    Georgievska, B.2    Björklund, A.3
  • 24
    • 0035011904 scopus 로고    scopus 로고
    • Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease
    • Kirik D., Geprgoevsla B., Rosenblad C., and Björklund A. Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease. Euro. J. Neurosci. 13 (2001) 1589-1599
    • (2001) Euro. J. Neurosci. , vol.13 , pp. 1589-1599
    • Kirik, D.1    Geprgoevsla, B.2    Rosenblad, C.3    Björklund, A.4
  • 25
    • 34250328819 scopus 로고    scopus 로고
    • Differential effects on forelimb grasping behavior induced by fetal dopaminergic grafts in hemiparkinsonian rats
    • Klein A., Metz G.A., Papazoglou A., and Nikkhah G. Differential effects on forelimb grasping behavior induced by fetal dopaminergic grafts in hemiparkinsonian rats. Neurobiol. Dis. 27 (2007) 24-35
    • (2007) Neurobiol. Dis. , vol.27 , pp. 24-35
    • Klein, A.1    Metz, G.A.2    Papazoglou, A.3    Nikkhah, G.4
  • 26
    • 0037148530 scopus 로고    scopus 로고
    • Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75 NTR
    • Lalli G., and Schiavo G. Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75 NTR. J. Cell Biol. 156 (2002) 233-239
    • (2002) J. Cell Biol. , vol.156 , pp. 233-239
    • Lalli, G.1    Schiavo, G.2
  • 27
    • 0027285510 scopus 로고
    • GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin L.F., Doherly D.H., Lile J.D., Bektesh S., and Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260 (1993) 1130-1132
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherly, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 28
    • 0036459952 scopus 로고    scopus 로고
    • Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
    • Lundblad M., Andersson M., Winkler C., Kirik D., Wierup N., and Cenci M.A. Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease. Euro. J. Neurosci. 15 1 (2002) 120-132
    • (2002) Euro. J. Neurosci. , vol.15 , Issue.1 , pp. 120-132
    • Lundblad, M.1    Andersson, M.2    Winkler, C.3    Kirik, D.4    Wierup, N.5    Cenci, M.A.6
  • 29
    • 30444460587 scopus 로고    scopus 로고
    • Motor complications in Parkinson's disease and the clinical significance of rotational behavior in the rat: have we wasted our time?
    • Marín C., Rodriguez-Oroz M.C., and Obeso J.A. Motor complications in Parkinson's disease and the clinical significance of rotational behavior in the rat: have we wasted our time?. Exp. Neurol. 197 (2006) 269-274
    • (2006) Exp. Neurol. , vol.197 , pp. 269-274
    • Marín, C.1    Rodriguez-Oroz, M.C.2    Obeso, J.A.3
  • 30
    • 0023114219 scopus 로고
    • Inhibition of mitochondrial NADH-ubiquinone oxidoreductase activity by 1-methyl-4-phenylpyridinium ion
    • Mizuno Y., Saitoh T., and Sone N. Inhibition of mitochondrial NADH-ubiquinone oxidoreductase activity by 1-methyl-4-phenylpyridinium ion. Biochem. Biophys. Res. Commun. 143 (1987) 294-309
    • (1987) Biochem. Biophys. Res. Commun. , vol.143 , pp. 294-309
    • Mizuno, Y.1    Saitoh, T.2    Sone, N.3
  • 31
    • 0026101797 scopus 로고
    • The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats
    • Montoya C.P., Campbell-Hope L.J., Pemberton K.D., and Dunnet S.B. The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats. J. Neurosci. Methods 36 (1991) 219-228
    • (1991) J. Neurosci. Methods , vol.36 , pp. 219-228
    • Montoya, C.P.1    Campbell-Hope, L.J.2    Pemberton, K.D.3    Dunnet, S.B.4
  • 34
    • 0037713489 scopus 로고    scopus 로고
    • The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model, a tool to explore the pathogenesis of Parkinson's disease
    • Przedborski S., and Vila M. The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model, a tool to explore the pathogenesis of Parkinson's disease. Ann. N.Y. Acad. Sci. 991 (2003) 189-198
    • (2003) Ann. N.Y. Acad. Sci. , vol.991 , pp. 189-198
    • Przedborski, S.1    Vila, M.2
  • 35
    • 0033950675 scopus 로고    scopus 로고
    • CNS platicity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury
    • Schallert T., Fleming S.M., Leasure J.L., Tillerson J.L., and Bland S.T. CNS platicity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury. Neuropharmacology 39 (2000) 777-787
    • (2000) Neuropharmacology , vol.39 , pp. 777-787
    • Schallert, T.1    Fleming, S.M.2    Leasure, J.L.3    Tillerson, J.L.4    Bland, S.T.5
  • 36
    • 0000431473 scopus 로고    scopus 로고
    • Intervention strategies for degeneration of dopamine neurons in parkinsonism: optimizing behavioral assessment of outcome
    • Emerich D.F., Dean R.L., and Sangerg P.R. (Eds), Humana Press Inc., Totowa, NJ
    • Schallert T., and Tillerson J.L. Intervention strategies for degeneration of dopamine neurons in parkinsonism: optimizing behavioral assessment of outcome. In: Emerich D.F., Dean R.L., and Sangerg P.R. (Eds). Central Nervous System Diseases (1999), Humana Press Inc., Totowa, NJ 131-151
    • (1999) Central Nervous System Diseases , pp. 131-151
    • Schallert, T.1    Tillerson, J.L.2
  • 37
    • 0032414776 scopus 로고    scopus 로고
    • Differential effects of GDNF treatment on rotational asymmetry, skilled forelimb use deficits and sensory neglect in unilateral 6-OHDA-lesioned rats
    • Schneider J.S., and Peacock V. Differential effects of GDNF treatment on rotational asymmetry, skilled forelimb use deficits and sensory neglect in unilateral 6-OHDA-lesioned rats. Restorative Neurol. Neurosci. 13 (1998) 205-212
    • (1998) Restorative Neurol. Neurosci. , vol.13 , pp. 205-212
    • Schneider, J.S.1    Peacock, V.2
  • 40
    • 0026773766 scopus 로고
    • MK-801 fails to protect against the dopaminergic neuropathology produced by systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice or nigral 1-methyl-4-phenylpyridinium in rats
    • Sonsalla P.K., Zeevalk G.D., Manzino L., Giovanni A., and Nicklas W.J. MK-801 fails to protect against the dopaminergic neuropathology produced by systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice or nigral 1-methyl-4-phenylpyridinium in rats. J. Neurochem. 58 (1992) 1979-1982
    • (1992) J. Neurochem. , vol.58 , pp. 1979-1982
    • Sonsalla, P.K.1    Zeevalk, G.D.2    Manzino, L.3    Giovanni, A.4    Nicklas, W.J.5
  • 41
    • 0027177628 scopus 로고
    • +) nigral toxicity in the rat by prior decortication or MK-801 treatment: a stereological estimate of neuronal loss
    • +) nigral toxicity in the rat by prior decortication or MK-801 treatment: a stereological estimate of neuronal loss. Neurobiol. Aging 14 (1993) 295-301
    • (1993) Neurobiol. Aging , vol.14 , pp. 295-301
    • Srivastava, R.1    Brouillet, E.2    Beal, M.F.3    Storey, E.4    Hyman, B.T.5
  • 42
    • 0029114190 scopus 로고
    • Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggest a trophic role in the adult
    • Tomac A., Widenfalk J., Lin L.F., Kohno T., Ebendal T., Hoffer B.J., and Olsson L. Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggest a trophic role in the adult. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 8274-8278
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 8274-8278
    • Tomac, A.1    Widenfalk, J.2    Lin, L.F.3    Kohno, T.4    Ebendal, T.5    Hoffer, B.J.6    Olsson, L.7
  • 43
    • 0014954436 scopus 로고
    • Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system
    • Ungerstedt U., and Arbuthnott G.W. Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system. Brain Res. 24 (1970) 485-493
    • (1970) Brain Res. , vol.24 , pp. 485-493
    • Ungerstedt, U.1    Arbuthnott, G.W.2
  • 44
    • 0025201875 scopus 로고
    • The structure of skilled forelimb reaching in the rat: a proximally driven movement with a single distal rotatory component
    • Whishaw I.Q., and Pellis S.M. The structure of skilled forelimb reaching in the rat: a proximally driven movement with a single distal rotatory component. Behav. Brain Res. 41 1 (1990) 49-59
    • (1990) Behav. Brain Res. , vol.41 , Issue.1 , pp. 49-59
    • Whishaw, I.Q.1    Pellis, S.M.2
  • 45
    • 33749253692 scopus 로고    scopus 로고
    • Neuronal death and growth factors: new therapeutic approaches in Parkinson's disease
    • Wider C., Burkhard P.R., Sajadi A., and Vingerhoets F.J. Neuronal death and growth factors: new therapeutic approaches in Parkinson's disease. Rev. Med. Suisse. 2 3 (64) (2006) 1158-1162
    • (2006) Rev. Med. Suisse. , vol.2 , Issue.3 64 , pp. 1158-1162
    • Wider, C.1    Burkhard, P.R.2    Sajadi, A.3    Vingerhoets, F.J.4


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