Controlled delivery of paclitaxel from stent coatings using novel styrene maleic anhydride copolymer formulations

Journal of Biomedical Materials Research - Part A

Volumn 90, Issue 2, 2009, Pages 522-532

  Richard, Robert ^a   Schwarz, Marlene ^a   Chan, Ken ^a   Teigen, Nikolai ^a   Boden, Mark ^a  

^a BOSTON SCIENTIFIC CORPORATION   (United States)

Author keywords

Coating; Coronary stent; Drug release; Paclitaxel; Polymer

Indexed keywords

AFM; COATED STENTS; COATING SURFACE; CONTROLLED DELIVERY; CONTROLLED RELEASE; CORONARY ARTERIES; CORONARY STENT; CORONARY STENTS; DRUG LOADING; DRUG RELEASE; ELASTOMER COATINGS; ELASTOMERIC POLYMER; GLASS TRANSITION TEMPERATURE; IN-VIVO; PACLITAXEL; RELEASE PROFILES; SEM; STENT COATINGS; STYRENE-MALEIC ANHYDRIDE; THERMAL ANALYSIS; VASCULAR RESPONSE;

ATOMIC FORCE MICROSCOPY; BIOCOMPATIBILITY; BUTENES; CHROMATOGRAPHIC ANALYSIS; COPOLYMERIZATION; DIFFERENTIAL SCANNING CALORIMETRY; GLASS TRANSITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MALEIC ANHYDRIDE; MECHANICAL PROPERTIES; POLYMERS; SCANNING; SCANNING ELECTRON MICROSCOPY; STAINLESS STEEL; STYRENE; THERMOANALYSIS;

PLASTIC COATINGS;

PACLITAXEL; POLY B STYRENE B ISOBUTYLENE B STYRENE; STYRENE DERIVATIVE; STYRENE MALEIC ANHYDRIDE COPOLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CORONARY STENT; DRUG ELUTING STENT; DRUG FORMULATION; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; NONHUMAN; SCANNING ELECTRON MICROSCOPY; TEMPERATURE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CALORIMETRY, DIFFERENTIAL SCANNING; CHROMATOGRAPHY, LIQUID; COATED MATERIALS, BIOCOMPATIBLE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; MALEIC ANHYDRIDES; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, SCANNING; PACLITAXEL; POLYMERS; STENTS; STYRENE; SWINE;

EID: 67650500353     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31969     Document Type: Article

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