Structures of native human thymidine phosphorylase and in complex with 5-iodouracil

Biochemical and Biophysical Research Communications

Volumn 386, Issue 4, 2009, Pages 666-670

  Mitsiki, Eirini ^a   Papageorgiou, Anastassios C ^a   Iyer, Shalini ^a   Thiyagarajan, Nethaji ^a   Prior, Steven H ^a   Sleep, Darrell ^b   Finnis, Chris ^b   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b Novozymes Biopharma DK A S   (United Kingdom)

Author keywords

5 Iodouracil; Crystal structure; Enzyme kinetics; Mutagenesis; Thymidine phosphorylase

Indexed keywords

5 IODURACIL; THYMIDINE PHOSPHORYLASE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; HUMAN; MOLECULAR INTERACTION; MUTAGENESIS; PRIORITY JOURNAL;

CRYSTALLOGRAPHY, X-RAY; HUMANS; MUTATION; PHOSPHATES; PROTEIN CONFORMATION; THYMIDINE PHOSPHORYLASE; URACIL;

EID: 67650459996     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.104     Document Type: Article

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