An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 27, 2009, Pages 11011-11015

  Rizk, Shahir S ^a   Luchniak, Anna ^a,b   Uysal, Serdar ^a   Brawley, Crista M ^a   Rock, Ronald S ^a   Kossiakoff, Anthony A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Actin; Drug delivery; Synthetic antibody fragment

Indexed keywords

ACTIN; ANTIBODY; NEUROKININ 1 RECEPTOR; REAGENT; SUBSTANCE P;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CONFORMATION; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; ENDOSOME; ENGINEERING; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; TECHNOLOGY; TUMOR CELL;

ACTINS; AMINO ACID SEQUENCE; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; HUMANS; IMMUNOGLOBULIN FRAGMENTS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; NEOPLASMS; PROTEIN BINDING; PROTEIN ENGINEERING; RECEPTORS, NEUROKININ-1; SUBSTANCE P;

MAMMALIA;

EID: 67650457494     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904907106     Document Type: Article

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