Serotonin Transporter Genotype and Depressive Symptoms Moderate Effects of Nicotine on Spatial Working Memory

Experimental and Clinical Psychopharmacology

Volumn 17, Issue 3, 2009, Pages 173-180

  Carlson, Joshua M ^a,b   Gilbert, David G ^a   Riise, Hege ^a   Rabinovich, Norka E ^a   Sugai, Chihiro ^a   Froeliger, Brett ^a,c  

^a SOUTHERN ILLINOIS UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

depression; genetics; nicotine; serotonin; spatial processing

Indexed keywords

NICOTINE; NICOTINE PATCH; PLACEBO; SEROTONIN TRANSPORTER;

ABSTINENCE; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; FEMALE; GENOTYPE; HUMAN; MALE; NICOTINE REPLACEMENT THERAPY; SPATIAL MEMORY; TASK PERFORMANCE; TOBACCO DEPENDENCE; WORKING MEMORY;

ADOLESCENT; ADULT; DEPRESSION; DOUBLE-BLIND METHOD; FEMALE; GENOTYPE; HIPPOCAMPUS; HUMANS; MALE; MEMORY; MIDDLE AGED; NICOTINE; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SPATIAL BEHAVIOR;

EID: 67650391267     PISSN: 10641297     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0016384     Document Type: Article

References (58)

1. Balfour D.J., and Ridley D.L. The effects of nicotine on neural pathways implicated in depression: A factor in nicotine addiction?. Pharmacology Biochememistry and Behavior 66 (2000) 79-85
2. Bence V.M., Sabourin C., Luty D.T., and Thackrey M. Differential sensitivity of the MMPI-2 depression scales and subscales. Journal of Clinical Psychology 51 (2006) 375-377
3. Bollini A.M., Arnold M.C., and Keefe R.S.E. Test-retest reliability of the dot test of visuospatial working memory in patients with schizophrenia and controls. Schizophrenia Research 45 (2000) 169-173
4. Breslau N., Kilbey M., and Andreski P. Nicotine dependence, major depression, and anxiety in young adults. Archives in General Psychiatry 48 (1991) 1069-1074
5. Campbell S., and Macqueen G. The role of the hippocampus in the pathophysiology of major depression. Journal of Psychiatry Neuroscience 29 (2004) 417-426
6. Carmody T.P. Affect regulation, nicotine addiction, and smoking cessation. Journal of Psychoactive Drugs 21 (1989) 331-342
7. Caspi A., Sugden K., Moffitt T.E., Taylor A., Craig I.W., Harrington H., et al. Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science 301 (2003) 386-389
8. Cinciripini P.M., Lapitsky L., Seay S., Wallfisch A., Meyer III W.J., and van Vunakis H. A placebo-controlled evaluation of the effects of buspironi on smoking cessation: Differences between high- and low-anxiety smoking cessation. Journal of Clinical Psychopharmacology 15 (1995) 182-191
9. Covey L.S., Glassman A.H., and Stetner F. Major depression following smoking cessation. American Journal of Psychiatry 154 (1997) 263-265
10. Davidson R.J. Anterior cerebral asymmetry and the nature of emotion. Brain and Cognition 20 (1992) 125-151
11. Davidson R.J., Pizzagalli D., Nitschke J.B., and Putnam K. Depression: Perspectives from affective neuroscience. Annual Reviews in Psychology 53 (2002) 545-574
12. Eysenck H.J. The causes and effects of smoking (1980), Sage, Beverly Hills, CA
13. Furmark T., Tillfors M., Garpenstrand H., Marteinsdottir I., Langstrom B., Oreland L., et al. Serotonin transporter polymorphism related to amygdala excitability and symptom severity in patients with social phobia. Neuroscience Letters 362 (2004) 189-192
14. George T.P., Vessicchio J.C., Termine A., Sahady D.M., Head C.A., Pepper W.T., et al. Effects of smoking abstinence on visuospatial working memory function in schizophrenia. Neuropsychopharmacology 26 (2002) 75-85
15. Gilbert D.G. Smoking: Individual differences, psychopathology, and emotion (1995), Taylor & Francis, Washington, DC
16. Gilbert D.G., Carlson J.M., Riise H., Rabinovich N.E., Sugai C., and Froeliger B. Effects of nicotine and depressive traits on affective priming of lateralized emotional word identification. Experimental and Clinical Psychopharmacology 16 (2008) 293-300
17. Gilbert D.G., McClernon F.J., Rabinovich N.E., Plath L., Masson C.L., Anderson A.E., et al. Mood disturbance fails to resolve across 31 days of cigarette abstinence in women. Journal of Consulting and Clinical Psychology 70 (2002) 142-152
18. Gilbert D.G., McClernon F.J., Rabinovich N.E., Sugai C., Plath L.C., Asgaard G., et al. Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits. Nicotine and Tobacco Research 6 (2004) 249-267
19. Gilbert D.G., Rabinovich N.E., Malpass D., Mrnak J., Riise H., Adams L., et al. Effects of nicotine on affect are moderated by stressor proximity and frequency, positive alternatives, and smoker status. Nicotine & Tobacco Research 10 (2008) 1171-1183
20. Gilbert D.G., Robinson J.H., Chamberlin C.L., and Spielberger C.D. Effects of smoking/nicotine on anxiety, heart rate, and lateralization of EEG during a stressful movie. Psychophysiology 26 (1989) 311-320
21. Gilbert D.G., Sharpe J.P., Ramanaiah N.V., Detwiler F.R.J., and Anderson A.E. Development of a Situation x Trait Adaptive Response (STAR) model-based smoking motivation questionnaire. Personality and Individual Differences 29 (2000) 65-84
22. Gilbert D.G., Zuo Y., Rabinovich N.E., Riise H., Needham R., and Huggenvik J.I. Neurotransmission-related genetic polymorphisms, negative affectivity traits, and gender predict tobacco abstinence symptoms across 44 days with and without nicotine patch. Journal of Abnormal Psychology 118 (2009) 322-334
23. Glassman A.H., Stetner F., Walsh B.T., Raizman P.S., Fleiss J.L., Cooper T.B., et al. Heavy smokers, smoking cessation, and clonidine. Results of a double-blind, randomized trial. Journal of the American Medical Association 259 (1988) 2863-2866
24. Gould N.F., Holmes M.K., Fantie B.D., Luckenbaugh D.A., Pine D.S., Gould T.D., et al. Performance on a virtual reality spatial memory navigation task in depressed patients. American Journal of Psychiatry 164 (2007) 516-519
25. Hariri A.R., and Holmes A. Genetics of emotional regulation: The role of the serotonin transporter in neural function. Trends in Cognitive Science 10 (2006) 182-191
26. Hariri A.R., Mattay V.S., Tessitore A., Kolachana B., Fera F., Goldman D., et al. Serotonin transporter genetic variation and the response of the human amygdala. Science 297 (2002) 400-403
27. Harrison A.A., Liem Y.T., and Markou A. Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats. Neuropsychopharmacology 25 (2001) 55-71
28. Hathaway S.R., and McKinley J.C. Minnesota Multiphasic Personality Inventory: Manual for administration and scoring (1983), University of Minnesota Press, Minneapolis
29. Heatherton T.F., Kozlowski L.T., Frecker R.C., and Fagerström K.O. The Fagerstrom Test for Nicotine Dependence: A revision of the Fagerström Tolerance Questionnaire. British Journal of Addiction 86 (1991) 1119-1127
30. Heinz A., Jones D.W., Mazzanti C., Goldman D., Ragan P., Hommer D., et al. A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity. Biological Psychiatry 47 (2000) 643-649
31. Heller W., Etienne M.A., and Miller G.A. Patterns of perceptual asymmetry in depression and anxiety: Implications for neuropsychological models of emotion and psychopathology. Journal of Abnormal Psychology 104 (1995) 327-333
32. Henriques J.B., and Davidson R.J. Brain electrical asymmetries during cognitive task performance in depressed and nondepressed subjects. Biological Psychiatry 42 (1997) 1039-1050
33. Hickie I., Naismith S., Ward P.B., Turner K., Scott E., Mitchell P., et al. Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression. British Journal of Psychiatry 186 (2005) 197-202
34. Hu S., Brody C.L., Fisher C., Gunzerath L., Nelson M.L., Sabol S.Z., et al. Interaction between the serotonin transporter gene and neuroticism in cigarette smoking behavior. Molecular Psychiatry 5 (2000) 181-188
35. Hughes J.R., Hatsukami D.K., Mitchell J.E., and Dahlgren L.A. Prevalence of smoking among psychiatric outpatients. American Journal of Psychiatry 143 (1986) 993-997
36. Joober R., Sengupta S., and Schmitz N. Serotonin transporter, stressful life events, and depression severity. American Journal of Psychiatry 164 (2007) 829-830
37. Kenny P.J., File S.E., and Rattray M. Nicotine regulates 5-HT(1A) receptor gene expression in the cerebral cortex and dorsal hippocampus. European Journal of Neuroscience 13 (2001) 1267-1271
38. Kirch D.G. Nicotine and major mental disorders. In: Piasecki M., and Newhouse P. (Eds). Nicotine in psychiatry: Psychopathology and emerging therapeutics (2000), American Psychiatric Press, Washington, DC
39. Lerman C., Caporaso N.E., Audrain J., Main D., Boyd N.R., and Shields P.G. Interacting effects of the serotonin transporter gene and neuroticism in smoking practices and nicotine dependence. Molecular Psychiatry 5 (2000) 189-192
40. Lesch K.P., Bengel D., Heils A., Sabol S.Z., Greenberg B.D., Petri S., et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274 (1996) 1527-1531
41. Lesch K.P., and Merschdorf U. Impulsivity, aggression, and serotonin: A molecular psychobiological perspective. Behavioral Sciences and the Law 18 (2000) 581-604
42. Little K.Y., McLaughlin D.P., Zhang L., Livermore C.S., Dalack G.W., McFinton P.R., et al. Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels. American Journal of Psychiatry 155 (1998) 207-213
43. MacMaster F.P., and Kusumakar V. Hippocampal volume in early onset depression. Biomedical Central Medicine 2 (2004) 2
44. Miller E.N., Fujioka T.A., Chapman L.J., and Chapman J.P. Hemispheric asymmetries of function in patients with major affective disorders. Journal of Psychiatric Research 29 (1995) 173-183
45. Munafò M.R., Roberts K., Johnstone E.C., Walton R.T., and Yudkin P.L. Association of serotonin transporter gene polymorphism with nicotine dependence: No evidence for an interaction with trait neuroticism. Personality and Individual Differences 38 (2005) 843-850
46. Newhouse P., Potter A., and Singh A. Effects of nicotinic stimulation on cognitive performance. Current Opinion in Pharmacology 4 (2004) 36-46
47. Newhouse P., Singh A., and Potter A. Nicotine and nicotinic receptor involvement in neuropsychoatric disorders. Current Topics in Medical Chemistry 4 (2004) 267-282
48. Newhouse P., and Whitehouse P. Nicotine cholinergic systems in Alzheimer's and Parkinson's Diseases. In: Piasecki M., and Newhouse P. (Eds). Nicotine in psychiatry: Psychopathology and emerging therapeutics (2000), American Psychiatric Press, Washington, DC
49. Perkins K.A., and Scott J. Sex differences in long-term smoking cessation rates due to nicotine patch. Nicotine and Tobacco Research 10 (2008) 1245-1250
50. Piasecki T.M., Niaura R., Shadel W.G., Abrams D., Goldstein M., Fiore M.C., et al. Smoking withdrawal dynamics in unaided quitters. Journal of Abnormal Psychology 109 (2000) 74-86
51. Rabe S., Debener S., Brocke B., and Beauducel A. Depression and its relation to posterior cortical activity during performance of neuropsychological verbal and spatial tasks. Personality and Individual Differences 39 (2005) 601-611
52. Ribeiro E.B., Bettiker R.L., Bogdanov M., and Wurtman R.J. Effects of systemic nicotine on serotonin release in rat brain. Brain Research 621 (1993) 311-318
53. Sacco K.A., Termine A., Seyal A., Dudas M.M., Vessicchio J.C., Krishnan-Sarin S., et al. Effects of cigarette smoking on spatial working memory and attentional deficits in schizophrenia: Involvement of nicotinic receptor mechanisms. Archives of General Psychiatry 62 (2005) 649-659
54. Sheline Y.I., Gado M.H., and Kraemer H.C. Untreated depression and hippocampal volume loss. American Journal of Psychiatry 160 (2003) 1516-1518
55. Sheline Y.I., Mittler B.L., and Mintun M.A. The hippocampus and depression. European Psychiatry 17 Suppl. 3 (2002) 300-305
56. Tamminga C.A., Nemeroff C.B., Blakely R.D., Brady L., Carter C.S., Davis K.L., et al. Developing novel treatments for mood disorders: Accelerating discovery. Biological Psychiatry 52 (2002) 589-609
57. Wetzler S., Kahn R., Strauman T.J., and Dubro A. Diagnosis of major depression by self-report. Journal of Personality Assessment 53 (1989) 22-30
58. Yonan A.L., Palmer A.A., and Gilliam T.C. Hardy-Weinberg disequilibrium identified genotyping error of the serotonin transporter (SLC6A4) promoter polymorphism. Psychiatric Genetics 16 (2006) 31-34