Construction and characterization of an oncolytic HSV vector containing a fusogenic glycoprotein and prodrug activation for enhanced local tumor control

Methods in Molecular Biology

Volumn 542, Issue , 2009, Pages 551-564

  Simpson, Guy R ^a   Coffin, Robert S ^b  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b Biovex Inc   (United States)

Author keywords

Cancer therapy; fusogenic membrane glycoproteins (FMG); herpes simplex virus type 1 (HSV 1); oncolytic prodrug activation therapy

Indexed keywords

GIBBON APE LEUKEMIA VIRUS; HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

GLYCOPROTEIN; HYBRID PROTEIN; ONCOLYTIC VIRUS; PRODRUG;

ANIMAL; ARTICLE; CELL DEATH; GENE VECTOR; GENETICS; HERPES SIMPLEX VIRUS; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR BIOLOGY; MOLECULAR CLONING; NEOPLASM; PLASMID; SACCHAROMYCES CEREVISIAE; TUMOR CELL LINE;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; CLONING, MOLECULAR; GENETIC VECTORS; GLYCOPROTEINS; HUMANS; MOLECULAR BIOLOGY; NEOPLASMS; ONCOLYTIC VIRUSES; PLASMIDS; PRODRUGS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SIMPLEXVIRUS;

EID: 67650305977     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-561-9_29     Document Type: Article

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