Confocal Raman microscopy to probe content uniformity of a lipid based powder for inhalation: A quality by design approach

European Journal of Pharmaceutical Sciences

Volumn 38, Issue 1, 2009, Pages 47-54

  Schoenherr, Carina ^a,b   Haefele, Thomas ^a   Paulus, Kurt ^a   Francese, Giancarlo ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Confocal Raman microscopy; Content uniformity; Inhalable spray dried powder; Liposome; Quality by design

Indexed keywords

LIPID; LIPOSOME; PLACEBO;

ARTICLE; CONFOCAL MICROSCOPY; CONFOCAL RAMAN MICROSCOPY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRY POWDER; POWDER; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SIGNAL PROCESSING; SOLID STATE; SPRAY DRYING;

ADMINISTRATION, INHALATION; CHEMISTRY, PHARMACEUTICAL; CHOLESTEROL; LIGHT; LIPIDS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; POWDERS; QUALITY CONTROL; SCATTERING, RADIATION; SPECTRUM ANALYSIS, RAMAN; UNILAMELLAR LIPOSOMES;

EID: 67650241711     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2009.05.011     Document Type: Article

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