A systematic review of four injection therapies for lateral epicondylosis: Prolotherapy, polidocanol, whole blood and platelet-rich plasma

British Journal of Sports Medicine

Volumn 43, Issue 7, 2009, Pages 471-481

  Rabago, David ^a   Best, T M ^b   Zgierska, A E ^c   Zeisig, E ^d   Ryan, M ^e   Crane, D ^f  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UMEÅ UNIVERSITY   (Sweden)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f Crane Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLIDOCANOL;

BIOMECHANICS; BLOOD AUTOTRANSFUSION; CLINICAL TRIAL; FOLLOW UP; HUMAN; PAIN; QUESTIONNAIRE; REVIEW; SCORING SYSTEM; SYSTEMATIC REVIEW; TENNIS ELBOW; THROMBOCYTE RICH PLASMA;

BLOOD TRANSFUSION, AUTOLOGOUS; HUMANS; INJECTIONS; NATUROPATHY; PLATELET-RICH PLASMA; POLYETHYLENE GLYCOLS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SCLEROSING SOLUTIONS; TENNIS ELBOW;

EID: 67650178852     PISSN: 03063674     EISSN: 14730480     Source Type: Journal    
DOI: 10.1136/bjsm.2008.052761     Document Type: Review

References (68)

1. Verhar J. Tennis elbow: anatomical, epidemiological and therapeutic aspects. Int Orthop 1994;18:263-267 (Pubitemid 24340722)
2. Hamilton P. The prevalence of humeral epicondylitis: a survey in general practice. J R Coll Gen Pract 1986;36:464-465
3. Kivi P. The etiology and conservative treatment of lateral epicondylitis. Scand J Rehabil Med 1983;15:37-41.
4. Ono Y, Nakamura R, Shimaoka M, et al. Epicondylitis among cooks in nursery schools. Occup Environ Med 1998;55:172-179
5. Ritz BR. Humeral epicondylitis among gas and waterworks employees. Scand J Work Environ Health 1995;21:478-486 (Pubitemid 26025272)
6. Hudak PL, Cole D, Haines T. Understanding prognosis to improve rehabilitation: Example of lateral elbow pain. Arch Phys Med Rehabil 1996;77:586-593 (Pubitemid 26180931)
7. Murtaugh JE. Tennis elbow. Aust Fam Phys 1988;17:90-95
8. Maffulli N, Khan KM, Kuddu G. Overuse tendon conditions: Time to change a confusing terminology. Arthroscopy 1998;14:840-843 (Pubitemid 28531671)
9. Khan KM, Cook JL, Kannus P, et al. Time to abandon the 'tendinitis' myth. BMJ 2002;324:626-627
10. Potter HG, Hannafin JA, Morwessel RM. Lateral epicondylitis: Correlation of MR imaging, surgical and histopathological findings. Radiology 1995;196:43-46
11. Stasinapoulos D, Johnson MI. 'Lateral elbow tendinopathy' is the most appropriate diagnostic term for the condition commonly referred to as lateral epicondylitis. Medical Hypotheses 2006;67:1399-1401.
12. Kraushaar BS, Nirschl RP. Tendinitis of the elbow (tennis elbow). Clinical features of histological, immunohistological, and electron microscopy studies. J Bone Joint Surg 1999;81-A:269-278
13. Rees JD, Wilson AM, Wolman RL. Current concepts in the management of tendon disorders. Rheumatology 2006;45:508-521
14. Bisset L, Paungmali A, Vicenzino B, et al. A systematic review and meta-analysis of clinical trials on physical interventions for lateral epicondylalgia. Br J Sports Med 2005;39:411-422 (Pubitemid 40942837)
15. Bisset L, Beller E, Jull G, et al. Mobilization with movement and exercise, corticosteroid injection or wait and see. BMJ 2006;333:939.
16. Croiser JL, Foidart-Dessalle M, Tinant F, et al. An isokinetic eccentric program for the management of chronic lateral epicondylar tendinopathy. Br J Sports Med 2007;41:269-275 (Pubitemid 350143342)
17. Buchbinder R, Green S, White M, et al. Shock wave therapy for lateral elbow pain. Cochrane Database Syst Rev 2005;(4):CD003524.
18. Smidt N, van der Windt DA, Assendelft WJ, et al. Corticosteroid injections, physiotherapy, or a wait-and-see policy for lateral epicondylitis: a randomised controlled trial. Lancet 2002;359:657-662 (Pubitemid 34203765)
19. Struijs PA, Smidt N, Arola H, et al. Orthotic devices for the treatment of tennis elbow. Cochrane Database Syst Rev. 2002;(1):CD001821.
20. Alfredson H, Ohberg L, Forsgren S. Is vasculo-neural ingrowth the cause of pain in chronic Achilles tendinosis? An investigation using ultrasonography and colour Doppler, immunohistochemistry, and diagnostic injections. Knee Surg Sports Traumatol Arthrosc 2003;11:334-338 (Pubitemid 38251124)
21. Alfredson H, Ohberg L. Neovascularisation in chronic painful patellar tendinosis-promising results after sclerosing neovessels outside the tendon challenge the need for surgery. Knee Surg Sports Traumatol Arthrosc 2005;13:74-80. (Pubitemid 40476078)
22. Scott A, Cook JL, Hart DA, et al. Tenocyte responses to mechanical loading in vivo. Arthritis and Rheumatism 2007;56:871-881
23. Zeisig E, Fahlström M, Ohberg L, et al. A 2-year sonographic follow-up after intratendinous injection therapy in patients with tennis elbow. Br J Sports Med Published Online First: 29 July 2008. doi:10.1136/bjsm.2008. 049874.
24. Hoksrud A, Ohberg L, Alfredson H, et al. Ultrasound-guided sclerosis of neovessels in painful chronic patellar tendinopathy. Am J Sports Med 2006;34:1738-1746
25. Zeisig E, Fahlström M, Ohberg L, Alfredson H. Pain relief after intratendinous injections in patients with Tennis elbow - results of a randomised study. Br J Sports Med 2008;42:267-271 (Pubitemid 351547689)
26. Alfredson H, Ohberg L. Sclerosing injections to areas of neovascularization reduce pain in chronic Achilles tendinopathy: a double-blind randomised trial. Knee Surg Sports Traumatol Arthrosc 2005;13:338-344 (Pubitemid 41217981)
27. Schultz L. A treatment for subluxation of the temporomandibular joint. JAMA 1937;109:1032-1035
28. Dagenais S, Ogunseitan O, Haldeman S, et al. Side effects and adverse events related to intraligamentous injection of sclerosing solutions (prolotherapy) for back and neck pain: a survey of practitioners. Arch Phys Med Rehabil 2006;87:909-913 (Pubitemid 43927577)
29. Rabago D, Best T, Beamsly M, et al. A systematic review of prolotherapy for chronic musculoskeletal pain. Clin J Sports Med 2005;15:376-380 (Pubitemid 41376963)
30. Topol GA, Reeves KD, Hassanein KM. Efficacy of dextrose prolotherapy in elite male kicking-sport athletes with groin pain. Arch Phys Rehabil 2005;86:697-702. (Pubitemid 40487835)
31. Scarpone M, Rabago D, Zgierska A, et al. The efficacy of prolotherapy for lateral epicondylosis: a pilot study. Clin J Sports Med 2008;18:248-254 (Pubitemid 351670429)
32. Suresh SPS, Ali KE, Jones H, et al. Medial epicondylitis: is ultrasound-guided autologous blood injection an effective treatment? Br J Sports Med 2006;40:935-939
33. Connell DA, Ali KE, Ahmad M, et al. Ultrasound-guided autologous blood injection for tennis elbow. Skeletal Radiol 2006;35:371-377 (Pubitemid 43676792)
34. Lee TG, Ahmad TS. Intralesional autologous blood injection compared to corticosteroid injection for treatment of chronic plantar fasciitis. A prospective, randomized, controlled trial. Foot Ankle Int 2007;28:984-990
35. Everts PAM, Knape JTA, Weibrich GW, et al. Platelet-rich plasma and platelet gel: A review. JECT 2006;38:174-187
36. Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered plateletrich plasma. Am J Sports Med 2006;34:1774-1778 (Pubitemid 44735517)
37. Gamradt SC, Rodeo SA, Warren RF. Platelet-rich plasma in rotator cuff repair. Techniques in Orthopedics 2007;22:26-33. (Pubitemid 46624333)
38. Randelli PS, Arrigoni P, Cabitza P, et al. Autologous platelet rich plasma for arthroscopic rotator cuff repair. A pilot study. Disabil Rehabil 2008;19:1-6.
39. Barrett B. Datasheet for Assessing Randomized Trials (DART). http://www.fammed. wisc.edu/wurss/1999.
40. Verhagen AP, DeVet HCW, DeBie RA, et al. The Delphi List: A criteria list for quality assessment of randomized trials conducting reviews developed by Delphi consensus. JCE 1998;51:1235-1241 (Pubitemid 29009523)
41. Pallant J. SPSS Survival Manual: A Step by Step Guide to Data Analysis Using SPSS. Allen & Unwin, 2007.
42. Ebell MH, Siwek J, Weiss BD, et al. Strength of recommendation taxonomy (SORT): a patient-centered approach to grading evidence in the medical literature. Am Fam Physician 2004;69:548-556 (Pubitemid 38176273)
43. Zeisig E, Ohberg L, Alfredson H. Sclerosing polidocanol injections in chronic painful elbow-promising results in a pilot study. Knee Surg Sports Traumatol Arthrosc 2006;14:1218-1224 (Pubitemid 44705172)
44. Glick RM. Prolotherapy for the treatment of lateral epicondylitis: A double-blind pilot study. North American Research Conference on Complementary and Integrative Medicine; 24-27 May 2006; Edmonton, Canada.
45. Lyftogt J. Subcutaneous prolotherapy treatment of refractory knee, shoulder and lateral elbow pain. Australasian Musculoskeletal Med 2007;12:110-112
46. Gani NU, Butt MF, Dhar SA, et al. Autologous Blood Injection In The Treatment Of Refractory Tennis Elbow. The Internet Journal of Orthopedic Surgery 2007;5. http:// www.ispub.com/ostia/index.php?xmlFilePath=journals/ijos/vol5n1/ tennis.xml
47. Edwards SG, Calandruccio JH. Autologous blood injections for refractory lateral epicondylitis. J Hand Surgery Am 2003;28:272-278 (Pubitemid 36373325)
48. Yelland MJ, Del Mar C, Pirozo S, et al. Prolotherapy injections for chronic low back pain: A systematic review. Spine 2004;29:2126-2133 (Pubitemid 40353201)
49. Farrar JT, Young JP, LaMoreaux L, et al. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical rating scale. Pain 2001;94:149-158 (Pubitemid 33016608)
50. Alfredson H, Cook JL. A treatment algorithm for managing Achilles tendinopathy: new treatment options. Br J Sports Med 2007;41:211-216 (Pubitemid 350143330)
51. Zeisig E, Ohberg L, Alfredson H. Extensor origin vascularity related to pain in patients with tennis elbow. Knee Surg Sports Traumatol Arthrosc 2006;14:659-663 (Pubitemid 44000078)
52. Ljung BO, Alfredson H, Forsgren S. Neurokinin 1-receptors and sensory neuropeptides in tendon insertions at the medial and lateral epicondyles of the humerus. Studies on tennis elbow and medial epicondylalgia. J Orthop Res 2004;22:321-327 (Pubitemid 38165257)
53. Fullerton B. High-resolution ultrasound and magnetic resonance imaging to document tissue repair after prolotherapy: a report of 3 cases. Arch Phys Med Rehabil 2008;89:377-385
54. Maxwell NJ, Ryan MB, Taunton JE, et al. Sonographically guided intratendinous injection of hyperosmolar dextrose to treat chronic tendinosis of the Achilles tendon: a pilot study. AJR Am J Roentgenol 2007;189:W215-W220.
55. Banks A. A rationale for prolotherapy. Journal of Orthopaedic Medicine 1991;13:54-59
56. Jensen K, Rabago D, Best TM, et al. Early inflammatory response of knee ligaments to prolotherapy in a rat model. J Orthop Res 2008;26:816-823 (Pubitemid 352000009)
57. Jensen KT, Rabago D, Best TM, et al. Longer term response of knee ligaments to prolotherapy in a rat injury model. Am J Sports Med 2008;36:1347-1357 (Pubitemid 352000009)
58. Liu YK, Tipton CM, Matthes RD, et al. An in-situ study of the influence of a sclerosing solution in rabbit medial collateral ligaments and its junction strength. Connect Tissue Res 1983;11:95-102.
59. Aneja A, Spero G, Weinhold P, et al. Suture plication, thermal shrinkage and sclerosing agents. Am J Sports Med 2005;33:1729-1734
60. Okuda Y, Adrogue H, Nakajima T, et al. Increased production of PDGF by angiotensin and high glucose in human vascular endothelium. Life Sci 1996;59:1455-1461 (Pubitemid 26344380)
61. Oh JH, Ha H, Yu MR, et al. Sequential effects of high glucose on mesangial cell transforming growth factor-B1 and fibronectin synthesis. Kidney Int 1998;54:1872-1878 (Pubitemid 28533615)
62. DiPaolo S, Gesualdo L, Ranieri E, et al. High glucose concentration induces the overexpression of transforming growth factor-B1 through the activation of a platelet-derived growth factor loop in human mesangial cells. Am J Pathol 1996;149:2095-2106 (Pubitemid 26415226)
63. Zochodne DW. Local events within the injured and regenerating peripheral nerve trunk: The role of the microenvironment and microcirculation. Biomedical Review 1997;8:37-54. (Pubitemid 29326795)
64. Schnabel LV, Mohammed HO, Miller BJ. Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum supeficialis tendons. J Orthop Res 2007;25:230-240 (Pubitemid 46344249)
65. Anitua E, Andia I, Sanchez M. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res 2005;23:281-286 (Pubitemid 40287850)
66. Anitua E, Sanchez M, Nurden AT. Autologous fibrin matrices: a potential source of biological mediators that modulate tendon activities. J Biomed Mater Res 2006;77:285-293 (Pubitemid 47233530)
67. Murray MM, Spindler KP, Abreu E. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res 2007;25:81-91. (Pubitemid 46070734)
68. Murray MM, Spindler KP, Devin C. Use of a collagen-platelet rich plasma scaffold to stimulate healing of a central defect in the canine. J Orthop Res 2006;24:820-830 (Pubitemid 43804978)