The efficacy of prolotherapy for lateral epicondylosis: A pilot study

Clinical Journal of Sport Medicine

Volumn 18, Issue 3, 2008, Pages 248-254

  Scarpone, Michael ^a   Rabago, David P ^a   Zgierska, Aleksandra ^a   Arbogast, Gennie ^a   Snell, Edward ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Injection therapy; Lateral epicondylosis; Prolotherapy; Tendinopathy

Indexed keywords

BUPIVACAINE; CODEINE; GLUCOSE; LIDOCAINE; MORRHUATE SODIUM; PARACETAMOL; SODIUM CHLORIDE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG THERAPY; DRUG TOLERABILITY; ELBOW; FEMALE; FOLLOW UP; GRIP STRENGTH; HUMAN; INJECTION SITE DISCOLORATION; INJECTION SITE DISCOMFORT; INJECTION SITE ERYTHEMA; INJECTION SITE IRRITATION; INJECTION SITE PAIN; MALE; OUTPATIENT DEPARTMENT; PAIN ASSESSMENT; PILOT STUDY; PRIORITY JOURNAL; PROLOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; TENNIS ELBOW; TREATMENT OUTCOME;

ADOLESCENT; ADULT; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FEMALE; HUMANS; INJECTIONS; MALE; MIDDLE AGED; OHIO; PILOT PROJECTS; TENNIS ELBOW; TREATMENT OUTCOME;

EID: 43449128113     PISSN: 1050642X     EISSN: None     Source Type: Journal    
DOI: 10.1097/JSM.0b013e318170fc87     Document Type: Article

References (50)

1. Verhar J. Tennis elbow: anatomical, epidemiological and therapeutic aspects. Int Orthop. 1994;18:263-267.
2. Hamilton P. The prevalence of humeral epicondylitis: a survey in general practice. J R Coll Gen Pract. 1986;36:464-465.
3. Kivi P. The etiology and conservative treatment of lateral epicondylitis. Scand J Rehabil Med. 1983;15:37-41.
4. Gabel GT. Acute and chronic tendinopathies at the elbow. Curr Opin Rheumatol. 1999;11:138-148.
5. Ono Y, Nakamura R, Shimaoka M, et al. Epicondylitis among cooks in nursery schools. Occup Environ Med. 1998;55:172-179.
6. Ritz BR. Humeral epicondylitis among gas and waterworks employees. Scand J Work Environ Health. 1995;21:478-486.
7. Maffulli N, Khan KM, Kuddu G. Overuse tendon conditions: time to change a confusing terminology. Arthroscopy. 1998;14:840-843.
8. Khan KM, Cook JL, Kannus P, et al. Time to abandon the 'tendinitis' myth. BMJ. 2002;324:626-627.
9. Potter HG, Hannafin JA, Morwessel RM. Lateral epicondylitis: correlation of MR imaging, surgical and histopathological findings. Radiology. 1995;196:43-46.
10. Buchbinder R, Green S, White M, et al. Shock wave therapy for lateral elbow pain. The Cochrane Collaboration. 2005;3.
11. Smidt N, van der Windt DA, Assendelft WJ, et al. Corticosteroid injections, physiotherapy, or a wait-and-see policy for lateral epicondylitis: a randomised controlled trial. Lancet. 2002;359:657-662.
12. Struijs PA, Smidt N, Arola H, et al. Orthotic devices for the treatment of tennis elbow. The Cochrane Collaboration. 2005;3.
13. Dagenais S, Ogunseitan O, Haldeman S, et al. Side effects and adverse events related to intraligamentous injection of sclerosing solutions (prolotherapy) for back and neck pain: a survey of practitioners. Arch Phys Med Rehabil. 2006;87:909-913.
14. Rabago D, Best T, Beamsly M, et al. A systematic review of prolotherapy for chronic musculoskeletal pain. Clinical J Sports Med. 2005;15:376-380.
15. Aneja A, Spero G, Weinhold P, et al. Suture plication, thermal shrinkage and sclerosing agents. Am J Sports Med. 2005;33:1729-1734.
16. Liu YK, Tipton CM, Matthes RD, et al. An in-situ study of the influence of a sclerosing solution in rabbit medial collateral ligaments and its junction strength. Connect Tissue Res. 1983;11:95-102.
17. Maynard JA, Pedrini VA, Pedrini-Mille A, et al. Morphological and biochemical effects of sodium morrhuate on tendons. J Orthop Res. 1985;3:236-248.
18. Hackett GS, Hemwall GA, Montgomery GA. Ligament and Tendon Relaxation Treated by Prolotherapy. 5th ed. Oak Park: Gustav A. Hemwall; 1993.
19. McGonagle D, Marzo-Ortega H, Benjamin M, et al. Report on the second international enthesitis workshop. Arthritis Rheum. 2003;48:896-905.
20. Linetsky FS, FRafael M, Saberski L. Pain management with regenerative injection therapy (RIT). In: Weiner RS, ed. Pain Management. Boca Raton: CRC Press; 2002:381-402.
21. Schnirring L. Are your patients asking about prolotherapy? Physician Sportsmed. 2000;28:15-17.
22. Matthews JH. Nonsurgical treatment of pain in lumbar spinal stenosis [Letter to the editor]. Am Fam Physician. 1999;59:280-284.
23. Yelland M, Glasziou P, Bogduk N, et al. Prolotherapy injections, saline injections, and exercises for chronic low back pain: a randomized trial. Spine. 2004;29:9-16.
24. Ongley MJ, Klein RG, Dorman TA, et al. A new approach to the treatment of chronic low back pain. Lancet. 1987;2:143-146.
25. Klein RG, Eek BC, DeLong WB, et al. A randomized double-blind trial of dextrose-glycerine-phenol injections for chronic, low back pain. J Spinal Disord. 1993;6:23-33.
26. Reeves KD, Hassanein K. Randomized prospective double-blind placebo-controlled study of dextrose prolotherapy for knee osteoarthritis with or without ACL laxity. Altern Ther Health M. 2000;6:68-80.
27. Reeves KD, Hassanein K. Randomized, prospective, placebo-controlled double-blind study of dextrose prolotherapy for osteoarthritic thumb and finger (DIP, PIP, and Trapeziometacarpal) joints: evidence of clinical efficacy. J Altern Complem Med. 2000;6:311-320.
28. Yelland MJ, Del Mar C, Pirozo S. Prolotherapy injections for chronic low back pain. Cochrane DB Syst Rev. 2004;(2):CD004059.
29. Mathiowetz V, Weber K, Volland G, et al. Reliability and validity of grip and pinch strength evaluations. J Hand Surg [Am]. 1984;9:222-226.
30. Innes E. Handgrip strength testing: a review of the literature. Aust Occ Ther J. 1999;46:120-140.
31. Lee G, Chan C, Hui-Chan C. Work profile and functional capacity of formwork carpenters at construction sites. Disabil Rehabil. 2001;23:9-14.
32. Pledger GW. Basic statistics: importance of adherence. J Clin Res Pharmacoepidemiol. 1992;6:77-81.
33. SPSS. SPSS for Windows, version 14.0 (statistical software). http://www.spss.com/spss/. 2007.
34. Cochran WG, Cox GM. Experimental Design. 2nd ed. New York: John Wiley & Sons, Inc.; 1957.
35. Cole JW, Grizzle JE. Applications of multivariate analysis of variance to repeated measures experiments. Biometrics. 1966;22:810-828.
36. Milliken GA, Johnson DE. Designed Experiments. In: Analysis of Messy Data. Vol 1. New York: Chapman & Hall; 1992.
37. Ebell MH, Siwek J, Weiss BD, et al. Strength of recommendation taxonomy (SORT): a patient-centered approach to grading evidence in the medical literature. Am Fam Physician. 2004;69:548-556.
38. Schwartz RG, Sagedy N. Prolotherapy: A literature review and retrospective study. J Neurol Orth Med S. 1991;12:220-223.
39. Farrar JT, Young JP, LaMoreaux L, et al. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical rating scale. Pain. 2001;94:149-158.
40. Lyftogt J. Prolotherapy and Achilles tendinopathy: a prospective pilot study of an old treatment. Australasian Musculoskeletal Medicine. 2005;10:16-19.
41. Zeisig E, Ohberg L, Alfredson H. Extensor origin vascularity related to pain in patients with tennis elbow. Knee Surg Sports Traumatol Arthrosc. 2006;14:659-663.
42. Connell DA, Ali KE, Ahmad M, et al. Ultrasound-guided autologous blood injection for tennis elbow. Skeletal Radiol. 2006;35:371-377.
43. Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med. 2006;34:1774-1778.
44. Martin SP. Chronic venous disease: update on treatment. Consultant. 2006;9:1-2.
45. Bartholomew JR, King T, Sahggal A, et al. Varicose veins: newer better treatments available. Clev Clin J Med. 2005;72:312-328.
46. Stronek DF, Hutton SW, Silvis SE. Sodium morrhuate stimulates granulocytes and damages erythrocytes and endothelial cells: probable mechanism of an adverse reaction during sclerotherapy. J Lab Clin Med. 1985;106:498-504.
47. Zeisig E, Ohberg L, Alfredson H. Sclerosing polidocanol injections in chronic painful elbow-promising results in a pilot study. Knee Surg Sports Traumatol Arthrosc. 2006;14:1218-1224.
48. Hoksrud A, Ohberg L, Alfredson H, et al. Ultrasound-guided sclerosis of neovessels in painful chronic patellar tendinopathy. Am J Sports Med. 2006;34:1738-1746.
49. Alfredson H, Ohberg L. Sclerosing injections to areas of neovascularization reduce pain in chronic Achilles tendinopathy: a double-blind randomised trial. Knee Surg Sports Traumatol Arthrosc. 2005;13:338-344.
50. Friedman LM, Furberg CD, DeMets DL. Fundamentals of Clinical Trials. 3rd edition. New York: Springer; 1998.