Antibody-specific detection of CAIX in breast and prostate cancers

Biochemical and Biophysical Research Communications

Volumn 386, Issue 3, 2009, Pages 488-492

  Li, Ying ^a   Wang, Hai ^a   Oosterwijk, Egbert ^b   Selman, Yamil ^a   Mira, Juan C ^a   Medrano, Theresa ^a   Shiverick, Kathleen T ^a   Frost, Susan C ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Tubulin; Antibody specificity; Breast cancer cells; CAIX; Hypoxia; Prostate cancer cells

Indexed keywords

BETA TUBULIN; CARBONATE DEHYDRATASE IX; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY M75; POLYCLONAL ANTIBODY; POLYCLONAL ANTIBODY NB100; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ARTICLE; BREAST CANCER; CANCER CELL; CELL LYSATE; CYTOPLASM; FEMALE; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOHISTOCHEMISTRY; MALE; MASS SPECTROMETRY; MEMBRANE BINDING; MOUSE; NONHUMAN; NUDE MOUSE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; TUMOR VOLUME; TUMOR XENOGRAFT; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEOPLASM; ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CARBONIC ANHYDRASES; CELL HYPOXIA; CELL LINE, TUMOR; CROSS REACTIONS; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; MALE; MICE; MICE, NUDE; PROSTATIC NEOPLASMS; TUBULIN; TUMOR MARKERS, BIOLOGICAL;

EID: 67650072493     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.06.064     Document Type: Article

References (20)

1. Parkkila S. An overview of the distribution and function of carbonic anhydrases in mammals. In: Chegwidden W.R., Carter N., and Edwards Y. (Eds). The Carbonic Anhydrases: New Horizons (2000), Birkhauser Verlag, Basel, Switzerland 76-93
2. Potter C., and Harris A.L. Hypoxia inducible carbonic anhydrase IX, marker of tumor hypoxia, survival pathway and therapy target. Cell Cycle 3 (2004) 164-167
3. Chia S.K., Wykoff C.C., Watson P.H., Han C., Leek R.D., Pastorek J., Gatter K.C., Ratcliffe P., and Harris A.L. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast cancer. J. Clin. Oncol. 19 (2005) 3660-3668
4. Hussain S.A., Ganesan R., Reynolds G., Gross L., Stevens A., Pastorek J., Murray P.G., Perunovic B., Anwar M.S., Billingham L., James N.D., Spooner D., Poole C.J., Rea D.W., and Palmer D.H. Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer. Br. J. Cancer 96 (2007) 104-109
5. Ord J.J., Agrawal S., Thamboo T.P., Roberts I., Campo L., Turley H., Han C., Fawcett D.W., Kulkarni L.P., Cranston D., and Harris A.L. An investigation into the prognostic significance of necrosis and hypoxia in high grade and invasive bladder cancer. J. Urol. 178 (2007) 677-682
6. Oosterwijk E., Ruiter D.J., Hoedemaeker Ph.J., Pauwels E.K.J., Jonas U., Zwartendijk I., and Warnaar S.O. Monclonal antibody G 250 recognizes a determinant present in renal-cell carcinoma and absent from normal kidney. Int. J. Cancer 38 (1986) 489-494
7. Grabmaier K., Vissers J.L.M., de Weijert M.C.A., Oosterwijk-Wakka J.C., Bokhoven A.V., Brakenhoff R.H., Noessner E., Mulders P.A., Merkx G., Figdor C.G., Adema G.J., and Oosterwijk E. Molecular cloning and immunogenicity of renal cell carcinoma-associated antigen G250. Int. J. Cancer 85 (2000) 865-870
8. Wykoff C.C., Beasley N.J.P., Watson P.H., Turner K.J., Pastorek J., Sibtain A., Wilson G.D., Turley H., Talks K.L., Maxwell P.H., Pugh C.W., Ratcliffe P.J., and Harris A.L. Hypoxia-inducible expression of tumor-associated carbonic anhydrase. Cancer Res. 60 (2000) 7075-7083
9. Wykoff C.C., Beasley N., Watson P.H., Campo L., Chia S.K., English R., Pastorek J., Sly W.S., Ratcliffe P., and Harris A.L. Expression of hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast. Am. J. Pathol. 158 (2001) 1011-1019
10. Sowter H.M., Raval R., Moore J., Ratcliffe P.J., and Harris A.L. Predominant role of hypoxia-inducible transcription factor (Hif)-1α versus Hif-2α in regulation of the transcriptional response to hypoxia. Cancer Res. 63 (2003) 6130-6134
11. Chiche J., Ilc K., Laferriere J., Trottier E., Dayan F., Mazure N.M., Brahimi-Horn M.C., and Pouyssegur J. Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res. 69 (2009) 358-368
12. Swinson D.E.B., Jones J.L., Richardson D., Wykoff C., Turley H., Pastorek J., Taub N., Harris A.L., and O'Bryne K.J. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. J. Clin. Oncol. 21 (2003) 473-482
13. Trastour C., Benizri E., Ettore F., Ramaioli A., Chamorey E., Pouyssegur J., and Berra E. HIF-1α and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome. Int. J. Cancer 120 (2007) 1451-1458
14. Pastorekova S., Zavadova Z., Kostal M., Babusikova O., and Zavada J. A novel quasi-viral agent, MaTu, is a two-component system. Virology 187 (1992) 620-626
15. Pastorek J., Pastorekova S., Callebaut I., Mornon J.P., Zelnik V., Opavsky R., Zatovicova M., Liao S., Portetelle D., Stanbridge E.J., Zavada J., Burny A., and Kettman R. Cloning and characterization of MN, a human tumor-associate protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 9 (1994) 2877-2888
16. Markwell M.A.K., Haas S.M., Lieber L.L., and Tolbert N.E. A modification of the lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal. Biochem. 87 (1978) 206-210
17. Semple-Rowland S.L., Adamus G., Cohen R.J., and Ulshafer R.J. A reliable two-dimensional gel electrophoresis procedure for separating neural proteins. Electrophoresis 12 (1991) 307-312
18. Y. Li, H. Wang, E. Oosterwijk, C. Tu, K.T. Shiverick, D.N. Silverman, S.C. Frost, Expression and activity of carbonic anhydrase ix is associated with metabolic dysfunction in MDA-MB-231 breast cancer cells, Cancer Investigation, 2009, doi: 10.1080/06357900802653464.
19. Saarnio J., Parkkila S., Parkkila A.-K., Waheed A., Casey M.C., Zhou X.Y., Pastoreková S., Pastorek J., Karttunen T., Haukipuro K., Kairaluoma M.I., and Sly W.S. Immunohistochemistry of carbonic anhydrase isozyme IX (MN/CA IX) in human gut reveals polarized expression in epithelial cells with the highest proliferative capacity. J. Histochem. Cytochem. 46 (1998) 497-504
20. Al-Ahmadie H.A., Alden D., Qin L., Olgac S., Fine S.W., Gopalan A., Russo P., Motzer R.J., Reuter V.E., and Tickoo S.K. Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies. Am. J. Surg. Pathol. 32 (2008) 377-382