N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cells

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 15, 2009, Pages 4178-4182

  Yamazaki, Yoshimitsu ^a   Kawano, Yasuhiro ^a   Yamanaka, Akiko ^a   Maruyama, Susumu ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Human; Inhibitor; Melanoma; Mouse; Phenolic acid; Serotonin; Tryptamine; Tyrosinase

Indexed keywords

5 METHOXYTRYPTAMINE; CHLORIDE; DIHYDROXYPHENYL DERIVATIVE; ENZYME INHIBITOR; KOJIC ACID; MONOPHENOL MONOOXYGENASE; N [(DIHYDROXYPHENYL)ACYL]SEROTONIN DERIVATIVE; N ACYLSEROTONIN DERIVATIVE; N CAFFEOYLSEROTONIN; N PROTOCATECHUOYLSEROTONIN; PHENOL; SEROTONIN; TYRAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACETYLATION; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MELANOMA CELL; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MELANOMA; MELANOMA, EXPERIMENTAL; MICE; MODELS, CHEMICAL; MONOPHENOL MONOOXYGENASE; PHENOL; PHENOLS; PYRONES; SEROTONIN;

EID: 67650002983     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.05.115     Document Type: Article

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