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Volumn 132, Issue 2, 2009, Pages 215-221

Reduced frequency of CD4+CD25HIGHFOXP3+ cells and diminished FOXP3 expression in patients with Common Variable Immunodeficiency: A link to autoimmunity?

Author keywords

Autoimmunity; Common Variable Immunodeficiency; FOXP3; Regulatory T cells

Indexed keywords

TRANSCRIPTION FACTOR FOXP3;

EID: 67650001664     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2009.03.519     Document Type: Article
Times cited : (82)

References (27)
  • 2
    • 0024538472 scopus 로고
    • Clinical and immunologic analyses of 103 patients with common variable immunodeficiency
    • Cunningham-Rundles C. Clinical and immunologic analyses of 103 patients with common variable immunodeficiency. J. Clin. Immunol. 9 (1989) 22-33
    • (1989) J. Clin. Immunol. , vol.9 , pp. 22-33
    • Cunningham-Rundles, C.1
  • 4
    • 0027538145 scopus 로고
    • Primary hypogammaglobulinaemia: a survey of clinical manifestations and complications
    • Hermaszewski R.A., and Webster A.D. Primary hypogammaglobulinaemia: a survey of clinical manifestations and complications. Q. J. Med. 86 (1993) 31-42
    • (1993) Q. J. Med. , vol.86 , pp. 31-42
    • Hermaszewski, R.A.1    Webster, A.D.2
  • 5
    • 0032976666 scopus 로고    scopus 로고
    • Common variable immunodeficiency: clinical and immunological features of 248 patients
    • Cunningham-Rundles C., and Bodian C. Common variable immunodeficiency: clinical and immunological features of 248 patients. Clin. Immunol. 92 (1999) 34-48
    • (1999) Clin. Immunol. , vol.92 , pp. 34-48
    • Cunningham-Rundles, C.1    Bodian, C.2
  • 7
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 6 (2005) 345-352
    • (2005) Nat. Immunol. , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 9
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot J.D., Gavin M.A., and Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4 (2003) 330-336
    • (2003) Nat. Immunol. , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 10
    • 0036857530 scopus 로고    scopus 로고
    • The role of suppressor T cells in regulation of immune responses
    • McHugh R.S., and Shevach E.M. The role of suppressor T cells in regulation of immune responses. J. Allergy Clin. Immunol. 110 (2002) 693-702
    • (2002) J. Allergy Clin. Immunol. , vol.110 , pp. 693-702
    • McHugh, R.S.1    Shevach, E.M.2
  • 12
    • 36349010693 scopus 로고    scopus 로고
    • The quantitative analysis of peripheral blood FOXP3-expressing T cells in systemic lupus erythematosus and rheumatoid arthritis patients
    • Lin S.C., Chen K.H., Lin C.H., Kuo C.C., Ling Q.D., and Chan C.H. The quantitative analysis of peripheral blood FOXP3-expressing T cells in systemic lupus erythematosus and rheumatoid arthritis patients. Eur. J. Clin. Invest. 37 (2007) 987-996
    • (2007) Eur. J. Clin. Invest. , vol.37 , pp. 987-996
    • Lin, S.C.1    Chen, K.H.2    Lin, C.H.3    Kuo, C.C.4    Ling, Q.D.5    Chan, C.H.6
  • 13
  • 14
    • 43249122144 scopus 로고    scopus 로고
    • Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance
    • Vargas-Rojas M.I., Crispin J.C., Richaud-Patin Y., and Alcocer-Varela J. Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance. Lupus 17 (2008) 289-294
    • (2008) Lupus , vol.17 , pp. 289-294
    • Vargas-Rojas, M.I.1    Crispin, J.C.2    Richaud-Patin, Y.3    Alcocer-Varela, J.4
  • 15
    • 33744904725 scopus 로고    scopus 로고
    • Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression
    • Venken K., Hellings N., Hensen K., Rummens J.L., Medaer R., D'Hooghe B., Dubois M.B., Raus J., and Stinissen P. Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression. J. Neurosci. Res. 83 (2006) 1432-1446
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1432-1446
    • Venken, K.1    Hellings, N.2    Hensen, K.3    Rummens, J.L.4    Medaer, R.5    D'Hooghe, B.6    Dubois, M.B.7    Raus, J.8    Stinissen, P.9
  • 16
    • 11244291391 scopus 로고    scopus 로고
    • Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis
    • Balandina A., Lecart S., Dartevelle P., Saoudi A., and Berrih-Aknin S. Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis. Blood 105 (2005) 735-741
    • (2005) Blood , vol.105 , pp. 735-741
    • Balandina, A.1    Lecart, S.2    Dartevelle, P.3    Saoudi, A.4    Berrih-Aknin, S.5
  • 18
    • 0030971165 scopus 로고    scopus 로고
    • Lack of specific antibody response in common variable immunodeficiency (CVID) associated with failure in production of antigen-specific memory T cells. MRC Immunodeficiency Group
    • Kondratenko I., Amlot P.L., Webster A.D., and Farrant J. Lack of specific antibody response in common variable immunodeficiency (CVID) associated with failure in production of antigen-specific memory T cells. MRC Immunodeficiency Group. Clin. Exp. Immunol. 108 (1997) 9-13
    • (1997) Clin. Exp. Immunol. , vol.108 , pp. 9-13
    • Kondratenko, I.1    Amlot, P.L.2    Webster, A.D.3    Farrant, J.4
  • 19
    • 0024391052 scopus 로고
    • Peripheral blood lymphocytes of patients with common variable immunodeficiency (CVI) produce reduced levels of interleukin-4, interleukin-2 and interferon-gamma, but proliferate normally upon activation by mitogens
    • Pastorelli G., Roncarolo M.G., Touraine J.L., Peronne G., Tovo P.A., and de Vries J.E. Peripheral blood lymphocytes of patients with common variable immunodeficiency (CVI) produce reduced levels of interleukin-4, interleukin-2 and interferon-gamma, but proliferate normally upon activation by mitogens. Clin. Exp. Immunol. 78 (1989) 334-340
    • (1989) Clin. Exp. Immunol. , vol.78 , pp. 334-340
    • Pastorelli, G.1    Roncarolo, M.G.2    Touraine, J.L.3    Peronne, G.4    Tovo, P.A.5    de Vries, J.E.6
  • 20
    • 34548491824 scopus 로고    scopus 로고
    • Tolerance and autoimmunity: lessons at the bedside of primary immunodeficiencies
    • Carneiro-Sampaio M., and Coutinho A. Tolerance and autoimmunity: lessons at the bedside of primary immunodeficiencies. Adv. Immunol. 95 (2007) 51-82
    • (2007) Adv. Immunol. , vol.95 , pp. 51-82
    • Carneiro-Sampaio, M.1    Coutinho, A.2
  • 21
    • 44449097509 scopus 로고    scopus 로고
    • Autoimmune manifestations in common variable immunodeficiency
    • Cunningham-Rundles C. Autoimmune manifestations in common variable immunodeficiency. J. Clin. Immunol. 28 Suppl. 1 (2008) S42-S45
    • (2008) J. Clin. Immunol. , vol.28 , Issue.SUPPL. 1
    • Cunningham-Rundles, C.1
  • 22
    • 33846796078 scopus 로고    scopus 로고
    • Low numbers of regulatory T cells in common variable immunodeficiency: association with chronic inflammation in vivo
    • Fevang B., Yndestad A., Sandberg W.J., Holm A.M., Muller F., Aukrust P., and Froland S.S. Low numbers of regulatory T cells in common variable immunodeficiency: association with chronic inflammation in vivo. Clin. Exp. Immunol. 147 (2007) 521-525
    • (2007) Clin. Exp. Immunol. , vol.147 , pp. 521-525
    • Fevang, B.1    Yndestad, A.2    Sandberg, W.J.3    Holm, A.M.4    Muller, F.5    Aukrust, P.6    Froland, S.S.7
  • 23
    • 44849125410 scopus 로고    scopus 로고
    • Altered frequency and migration capacity of CD4+CD25+ regulatory T cells in systemic lupus erythematosus
    • Lee H.Y., Hong Y.K., Yun H.J., Kim Y.M., Kim J.R., and Yoo W.H. Altered frequency and migration capacity of CD4+CD25+ regulatory T cells in systemic lupus erythematosus. Rheumatology (Oxford) 47 (2008) 789-794
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 789-794
    • Lee, H.Y.1    Hong, Y.K.2    Yun, H.J.3    Kim, Y.M.4    Kim, J.R.5    Yoo, W.H.6
  • 25
    • 8644277177 scopus 로고    scopus 로고
    • Assessing thymopoiesis in patients with common variable immunodeficiency as measured by T-cell receptor excision circles
    • De Vera M.J., Al-Harthi L., and Gewurz A.T. Assessing thymopoiesis in patients with common variable immunodeficiency as measured by T-cell receptor excision circles. Ann. Allergy Asthma Immunol. 93 (2004) 478-484
    • (2004) Ann. Allergy Asthma Immunol. , vol.93 , pp. 478-484
    • De Vera, M.J.1    Al-Harthi, L.2    Gewurz, A.T.3
  • 27
    • 33847125247 scopus 로고    scopus 로고
    • Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
    • Wan Y.Y., and Flavell R.A. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 445 (2007) 766-770
    • (2007) Nature , vol.445 , pp. 766-770
    • Wan, Y.Y.1    Flavell, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.