Drug reinforcement in a rat model of attention deficit/hyperactivity disorder - The spontaneously hypertensive rat (SHR)

Current Drug Abuse Reviews

Volumn 2, Issue 2, 2009, Pages 177-183

  Vendruscolo, Leandro F ^a   Izídio, Geison S ^b   Takahashi, Reinaldo N ^b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Alcoholism; Dopamine; Drug dependence; Psychiatric comorbidity; Sex differences

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; ALCOHOL; CANNABINOID; CANNABINOID 1 RECEPTOR; COCAINE; METHYLPHENIDATE; MORPHINE; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; NICOTINE; OPIATE; PSYCHOSTIMULANT AGENT; VANOXERINE; CENTRAL STIMULANT AGENT;

ALCOHOL CONSUMPTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION DEFICIT DISORDER; COMORBIDITY; CONDITIONING; DISEASE MODEL; DRINKING BEHAVIOR; DRUG DEPENDENCE; DRUG DOSE COMPARISON; LOCOMOTION; NEUROCHEMISTRY; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; REINFORCEMENT; SENSITIVITY ANALYSIS; SEX DIFFERENCE; SPONTANEOUSLY HYPERTENSIVE RAT; STRAIN DIFFERENCE; TRANQUILIZING ACTIVITY; TREATMENT OUTCOME; WISTAR KYOTO RAT; ANIMAL; FEMALE; MALE; PSYCHOLOGICAL ASPECT; REVIEW; SEXUAL DEVELOPMENT;

ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CENTRAL NERVOUS SYSTEM STIMULANTS; DISEASE MODELS, ANIMAL; FEMALE; MALE; METHYLPHENIDATE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; REINFORCEMENT (PSYCHOLOGY); SEX CHARACTERISTICS;

EID: 67649948508     PISSN: 18744737     EISSN: None     Source Type: Journal    
DOI: 10.2174/1874473710902020177     Document Type: Article

References (78)

1. Biederman J, Faraone SV, Spencer T, Wilens T, Mick E, Lapey KA. Gender differences in a sample of adults with attention deficit hyperactivity disorder. Psychiatry Res 1994; 53(1): 13-29.
2. Murphy K, Barkley RA. Attention deficit hyperactivity disorder adults: comorbidities and adaptive impairments. Compr Psychiatry 1996; 37(6): 393-401.
3. Faraone SV, Biederman J. What is the prevalence of adult ADHD? Results of a population screen of 966 adults. J Atten Disord 2005; 9(2): 384-91.
4. Kessler RC, Adler L, Barkley R, et al. The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication. Am J Psychiatry 2006; 163(4): 716-23.
5. Wilens TE, Biederman J, Mick E. Does ADHD affect the course of substance abuse? Findings from a sample of adults with and without ADHD. Am J Addict 1998; 7(2): 156-63.
6. Lambert NM, Hartsough CS. Prospective study of tobacco smoking and substance dependencies among samples of ADHD and non-ADHD participants. J Learn Disabil 1998; 31(6): 533-44.
7. Gordon SM, Tulak F, Troncale J. Prevalence and characteristics of adolescents patients with co-occurring ADHD and substance dependence. J Addict Dis 2004; 23(4): 31-40.
8. Wilens TE, Kwon A, Tanguay S, et al. Characteristics of adults with attention deficit hyperactivity disorder plus substance use disorder: the role of psychiatric comorbidity. Am J Addict 2005; 14(4): 319-27.
9. Kollins SH. ADHD, Substance Use Disorders, and Psychostimulant Treatment: Current Literature and Treatment Guidelines. J Atten Disord 2008; 12(2): 115-25.
10. Ohlmeier MD, Peters K, Te Wildt BT, et al. Comorbidity of alcohol and substance dependence with attention-deficit/hyperactivity disorder (ADHD). Alcohol Alcohol 2008; 43(3): 300-4.
11. Russell VA. The nucleus accumbens motor-limbic interface of the spontaneously hypertensive rat as studied in vitro by the superfusion slice technique. Neurosci Biobehav Rev 2000; 24(1): 133-6.
12. Thapar A, O'Donovan M, Owen MJ. The genetics of attention deficit hyperactivity disorder. Hum Mol Genet 2005; 14: R275-82.
13. Feltenstein MW, See RE. The neurocircuitry of addiction: an overview. Br J Pharmacol 2008; 154(2): 261-74.
14. Kohnke MD. Approach to the genetics of alcoholism: a review based on pathophysiology. Biochem Pharmacol 2008; 75(1): 160-77.
15. Biederman J, Wilens T, Mick E, Spencer T, Faraone SV. Pharmacotherapy of attention-deficit/hyperactivity disorder reduces risk for substance use disorder. Pediatrics 1999; 104(2): e20.
16. Sagvolden T, Russell VA, Aase H, Johansen EB, Farshbaf M. Rodent models of attention-deficit/hyperactivity disorder. Biol Psychiatry 2005; 57(11): 1239-47.
17. Davids E, Zhang K, Tarazi FI, Baldessarini RJ. Animal models of attention-deficit hyperactivity disorder. Brain Res Brain Res Rev 2003; 42(1): 1-21.
18. Leo D, Sorrentino E, Volpicelli F, et al. Altered midbrain dopaminergic neurotransmission during development in an animal model of ADHD. Neurosci Biobehav Rev 2003; 27(7): 661-9.
19. Russell VA, Sagvolden T, Johansen EB. Animal models of attention-deficit hyperactivity disorder. Behav Brain Funct 2005; 1: 9.
20. Heal DJ, Smith SL, Kulkarni HL, Rowley HL. New perspectives from microdialysis studies in freely-moving, spontaneously hypertensive rats on the pharmacology of drugs for the treatment of ADHD. Pharmacol Biochem Behav 2008; 90(2): 184-97.
21. Okamoto K, Aoki K. Development of a strain of spontaneously hypertensive rats. Jpn Circ J 1963; 27: 282-93.
22. McCarty R. Stress, behavior and experimental hypertension. Neurosci Biobehav Rev 1983; 7(4): 493-502.
23. Lerman LO, Chade AR, Sica V, Napoli C. Animal models of hypertension: an overview. J Lab Clin Med 2005; 146(3): 160-73.
24. Sagvolden T, Metzger MA, Schiorbeck HK, Rugland AL, Spinnangr I, Sagvolden G. The spontaneously hypertensive rat (SHR) as an animal model of childhood hyperactivity (ADHD): changed reactivity to reinforcers and to psychomotor stimulants. Behav Neural Biol 1992; 58(2): 103-12.
25. Sagvolden T. Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit/hyperactivity disorder (AD/HD). Neurosci Biobehav Rev 2000; 24(1): 31-9.
26. Da Silva GE, Vendruscolo LF, Takahashi RN. Effects of ethanol on locomotor and anxiety-like behaviors and the acquisition of ethanol intake in Lewis and spontaneously hypertensive rats. Life Sci 2005; 77(6): 693-706.
27. Mill J, Sagvolden T, Asherson P. Sequence analysis of Drd2, Drd4, and Dat1 in SHR and WKY rat strains. Behav Brain Funct 2005; 1: 24.
28. Sagvolden T, Aase H, Johansen EB, Russel VA. A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes. Behav Brain Sci 2005; 28: 397-468.
29. DiMaio S, Grizenko N, Joober R. Dopamine genes and attentiondeficit hyperactivity disorder: a review. J Psychiatry Neurosci 2003; 28(1): 27-38.
30. Leonard BE, McCartan D, White J, King DJ. Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects. Hum Psychopharmacol 2004; 19(3): 151-80.
31. Yang PB, Amini B, Swann AC, Dafny N. Strain differences in the behavioral responses of male rats to chronically administered methylphenidate. Brain Res 2003; 971(2): 139-52.
32. Amini B, Yang PB, Swann AC, Dafny N. Differential locomotor responses in male rats from three strains to acute methylphenidate. Int J Neurosci 2004; 114(9): 1063-84.
33. Tsai CF, Lin MT. Locomotor hyperactivity in hypertensive rats. Pharmacology 1988; 36(1): 27-34.
34. Diaz Heijtz R, Castellanos FX. Differential effects of a selective dopamine D1-like receptor agonist on motor activity and c-fos expression in the frontal-striatal circuitry of SHR and Wistar-Kyoto rats. Behav Brain Funct 2006; 2: 18.
35. Pamplona FA, Vendruscolo LF, Takahashi RN. Increased sensitivity to cocaine-induced analgesia in Spontaneously Hypertensive Rats (SHR). Behav Brain Funct 2007; 3: 9.
36. Wise RA, Bozarth MA. A psychomotor stimulant theory of addiction. Psychol Rev 1987; 94(4): 469-92.
37. Franklin KB. Analgesia and abuse potential: an accidental association or a common substrate? Pharmacol Biochem Behav 1998; 59(4): 993-1002.
38. van den Buuse M, de Jong W. Differential effects of dopaminergic drugs on open-field behavior of spontaneously hypertensive rats and normotensive Wistar-Kyoto rats. J Pharmacol Exp Ther 1989; 248(3): 1189-96.
39. Yang PB, Swann AC, Dafny N. Acute and chronic methylphenidate dose-response assessment on three adolescent male rat strains. Brain Res Bull 2006; 71(1-3): 301-10.
40. Wultz B, Sagvolden T, Moser EI, Moser MB. The spontaneously hypertensive rat as an animal model of attention-deficit hyperactivity disorder: effects of methylphenidate on exploratory behavior. Behav Neural Biol 1990; 53(1): 88-102.
41. Hynes MD, Langer DH, Hymson DL, Pearson DV, Fuller RW. Differential effects of selected dopaminergic agents on locomotor activity in normotensive and spontaneously hypertensive rats. Pharmacol Biochem Behav 1985; 23(3): 445-8.
42. Robinson TE, Berridge KC. Incentive-sensitization and addiction. Addiction 2001; 96(1): 103-14.
43. Vendruscolo LF, Vendruscolo JCM, Terenina-Rigaldie E, et al. Marker-assisted dissection of genetic influences on motor and neuroendocrine sensitization to cocaine in rats. Genes Brain and Behav 2009; doi:10.1111/j.1601-183X.2008.00465.x
44. Cailhol S, Mormède P. Strain and sex differences in the locomotor response and behavioral sensitization to cocaine in hyperactive rats. Brain Res 1999; 842(1): 200-5.
45. Cailhol S, Mormède P. Effects of cocaine-induced sensitization on ethanol drinking: sex and strain differences. Behav Pharmacol 2000; 11(5): 387-94.
46. Augustyniak PN, Kourrich S, Rezazadeh SM, Stewart J, Arvanitogiannis A. Differential behavioral and neurochemical effects of cocaine after early exposure to methylphenidate in an animal model of attention deficit hyperactivity disorder. Behav Brain Res 2006; 167(2): 379-82.
47. Crabbe JC, Wahlsten D, Dudek BC. Genetics of mouse behavior: interactions with laboratory environment. Science 1999; 284(5420): 1670-2.
48. Khanna JM, Kalant H, Chau AK, Sharma H. Initial sensitivity, acute tolerance and alcohol consumption in four inbred strains of rats. Psychopharmacology (Berl) 1990; 101(3): 390-5.
49. Koob GF. Alcoholism: Allostasis and Beyond. Alcohol Clin Exp Res 2003; 27(2): 232-43.
50. Da Silva GE, Ramos A, Takahashi RN. Comparison of voluntary ethanol intake by two pairs of rat lines used as genetic models of anxiety. Braz J Med Biol Res 2004; 37(10): 1511-7.
51. Vendruscolo LF, Terenina-Rigaldie E, Raba F, Ramos A, Takahashi RN, Mormède P. Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats. Genes Brain Behav 2006; 5(6): 441-50.
52. Tordoff MG, Alarcon LK, Lawler MP. Preferences of 14 rat strains for 17 taste compounds. Physiol Behav 2008; 95(3): 308-32.
53. Chiavegatto S, Izidio GS, Mendes-Lana A, et al. Expression of alpha-synuclein is increased in the hippocampus of rats with high levels of innate anxiety. Mol Psychiatry 2008; doi: 10.1038/mp.2008.43.
54. Cailhol S, Mormède P. Sex and strain differences in ethanol drinking: effects of gonadectomy. Alcohol Clin Exp Res 2001; 25(4): 594-9.
55. Cailhol S, Mormède P. Conditioned taste aversion and alcohol drinking: strain and gender differences. J Stud Alcohol 2002; 63(1): 91-9.
56. Soeters HS, Howells FM, Russell VA. Methylphenidate does not increase ethanol consumption in a rat model for attention-deficit hyperactivity disorder-the spontaneously hypertensive rat. Metab Brain Dis 2008; 23(3): 303-14.
57. Vendruscolo LF, Izidio GS, Takahashi RN, Ramos A. Chronic methylphenidate treatment during adolescence increases anxietyrelated behaviors and ethanol drinking in adult spontaneously hypertensive rats. Behav Pharmacol 2008; 19(1): 21-7.
58. Cloninger CR. Neurogenetic adaptive mechanisms in alcoholism. Science 1987; 236(4800): 410-6.
59. Johnson DE, Waid LR, Anton RF. Childhood hyperactivity, gender, and Cloninger's personality dimensions in alcoholics. Addict Behav 1997; 22(5): 649-53.
60. Adriani W, Caprioli A, Granstrem O, Carli M, Laviola G. The spontaneously hypertensive-rat as an animal model of ADHD: evidence for impulsive and non-impulsive subpopulations. Neurosci Biobehav Rev 2003; 27(7): 639-51.
61. Beltramo M, de Fonseca FR, Navarro M, et al. Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor. J Neurosci 2000; 20(9): 3401-7.
62. Pandolfo P, Pamplona FA, Prediger RD, Takahashi RN. Increased sensitivity of adolescent spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder, to the locomotor stimulation induced by the cannabinoid receptor agonist WIN 55,212-2. Eur J Pharmacol 2007; 563(1-3): 141-8.
63. Bhargava HN, Gulati A. Kappa opioid receptor activity in spontaneously hypertensive rats. J Pharmacol Exp Ther 1988; 245(2): 460-5.
64. Bhargava HN, Villar VM. Pharmacodynamics and pharmacokinetics of intravenously administered morphine in spontaneously hypertensive and normotensive Wistar-Kyoto rats. J Pharmacol Exp Ther 1992; 261(1): 290-6.
65. Hoffmann O, Plesan A, Wiesenfeld-Hallin Z. Genetic differences in morphine sensitivity, tolerance and withdrawal in rats. Brain Res 1998; 806(2): 232-7.
66. Quock RM, Vaughn LK, Barlament J, Wojcechowskyj JA. Sex and strain differences in morphine-induced temperature effects in WKYs and SHRs. Brain Res Bull 1985; 14(4): 323-6.
67. Mahinda TB, Lovell BM, Taylor BK. Morphine-induced analgesia, hypotension, and bradycardia are enhanced in hypertensive rats. Anesth Analg 2004; 98(6): 1698-704.
68. Rahmani NH, Gulati A, Bhargava HN. Opiate antagonist binding sites in discrete brain regions of spontaneously hypertensive and normotensive Wistar-Kyoto rats. Life Sci 1991; 48(26): 2499-504.
69. Bhargava HN, Villar VM, Rahmani NH, Larsen AK. Time course of the distribution of morphine in brain regions and spinal cord after intravenous injection to spontaneously hypertensive and normotensive Wistar-Kyoto rats. J Pharmacol Exp Ther 1992; 261(3): 1008-14.
70. Gattu M, Pauly JR, Boss KL, Summers JB, Buccafusco JJ. Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. I. Brain Res 1997; 771(1): 89-103.
71. Gattu M, Terry AV Jr, Pauly JR, Buccafusco JJ. Cognitive impairment in spontaneously hypertensive rats: role of central nicotinic receptors. Part II. Brain Res 1997; 771(1): 104-14.
72. Hohnadel EJ, Hernandez CM, Gearhart DA, Terry AV Jr. Effect of repeated nicotine exposure on high-affinity nicotinic acetylcholine receptor density in spontaneously hypertensive rats. Neurosci Lett 2005; 382(1-2): 158-63.
73. Spear L. Modeling adolescent development and alcohol use in animals. Alcohol Res Health 2000; 24(2): 115-23.
74. Belin D, Mar AC, Dalley JW, Robbins TW, Everitt BJ. High impulsivity predicts the switch to compulsive cocaine-taking. Science 2008; 320(5881): 1352-5.
75. Kreek MJ, Nielsen DA, Butelman ER, LaForge KS. Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction. Nat Neurosci 2005; 8(11): 1450-7.
76. Johansen EB, Sagvolden T. Slower extinction of responses maintained by intra-cranial self-stimulation (ICSS) in an animal model of attention-deficit/hyperactivity disorder (ADHD). Behav Brain Res 2005; 162: 22-31.
77. Ferguson SA, Paule MG, Cada A, Fogle CM, Gray EP, Berry KJ. Baseline behavior, but not sensitivity to stimulant drugs, differs among spontaneously hypertensive, Wistar-Kyoto, and Sprague-Dawley rat strains. Neurotoxicol Teratol 2007; 29(5): 547-61.
78. Hendley ED, Atwater DG, Myers MM, Whitehorn D. Dissociation of genetic hyperactivity and hypertension in SHR. Hypertension 1983; 5(2): 211-7.