메뉴 건너뛰기




Volumn 6, Issue 7, 2009, Pages 1794-1808

2009 update on phosphodiesterase type 5 inhibitor therapy part 1: Recent studies on routine dosing for penile rehabilitation, lower urinary tract symptoms, and other indications (CME)

Author keywords

Daily dosing; Erectile dysfunction; Lower urinary tract symptoms; Penile rehabilitation; Phosphodiesterase type 5 inhibitors; Stuttering priapism

Indexed keywords

3 NITROTYROSINE; 8 ISOPROSTANE; ALFUZOSIN; CATALASE; CYCLIC GMP; DOXAZOSIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; FLUTAMIDE; GLUTATHIONE PEROXIDASE; INTERLEUKIN 8; LOSARTAN; NORADRENALIN; PHOSPHODIESTERASE V INHIBITOR; PLACEBO; SILDENAFIL; SK 3530; SUPEROXIDE DISMUTASE; TACROLIMUS; TADALAFIL; TAMSULOSIN; UDENAFIL; UNCLASSIFIED DRUG; VARDENAFIL; IMIDAZOLE DERIVATIVE; PHOSPHODIESTERASE INHIBITOR; PIPERAZINE DERIVATIVE; PURINE DERIVATIVE; SULFONE; TRIAZINE DERIVATIVE; VASODILATOR AGENT;

EID: 67649887476     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2009.01347.x     Document Type: Article
Times cited : (48)

References (53)
  • 2
    • 34548297591 scopus 로고    scopus 로고
    • Daily administration of phosphodiesterase type 5 inhibitors for urological and nonurological indications
    • Bella AJ, DeYoung LX, Al-Numi M, Brock GB. Daily administration of phosphodiesterase type 5 inhibitors for urological and nonurological indications. Eur Urol 2007;52:990-1005.
    • (2007) Eur Urol , vol.52 , pp. 990-1005
    • Bella, A.J.1    DeYoung, L.X.2    Al-Numi, M.3    Brock, G.B.4
  • 3
    • 38149131204 scopus 로고    scopus 로고
    • Rationale for phosphodiesterase 5 inhibitor use post-radical prostatectomy: Experimental and clinical review
    • Rambhatla A, Kovanecz I, Ferrini M, Gonzalez-Cadavid NF, Rajfer J. Rationale for phosphodiesterase 5 inhibitor use post-radical prostatectomy: Experimental and clinical review. Int J Impot Res 2008;20:30-4.
    • (2008) Int J Impot Res , vol.20 , pp. 30-34
    • Rambhatla, A.1    Kovanecz, I.2    Ferrini, M.3    Gonzalez-Cadavid, N.F.4    Rajfer, J.5
  • 4
    • 57649184019 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 inhibitors in postprostatectomy erectile dysfunction: A critical analysis of the basic science rationale and clinical application
    • Hatzimouratidis K, Burnett AL, Hatzichristou S, McCullough AR, Montorsi F, Mulhall JP. Phosphodiesterase type 5 inhibitors in postprostatectomy erectile dysfunction: A critical analysis of the basic science rationale and clinical application. Eur Urol 2009;55:334-47.
    • (2009) Eur Urol , vol.55 , pp. 334-347
    • Hatzimouratidis, K.1    Burnett, A.L.2    Hatzichristou, S.3    McCullough, A.R.4    Montorsi, F.5    Mulhall, J.P.6
  • 5
    • 58149181332 scopus 로고    scopus 로고
    • Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction
    • Bivalacqua TJ, Sussan TE, Gebska MA, Strong TD, Berkowitz DE, Biswal S, Burnett AL, Champion HC. Sildenafil inhibits superoxide formation and prevents endothelial dysfunction in a mouse model of secondhand smoke induced erectile dysfunction. J Urol 2009;181:899-906.
    • (2009) J Urol , vol.181 , pp. 899-906
    • Bivalacqua, T.J.1    Sussan, T.E.2    Gebska, M.A.3    Strong, T.D.4    Berkowitz, D.E.5    Biswal, S.6    Burnett, A.L.7    Champion, H.C.8
  • 6
    • 40649118790 scopus 로고    scopus 로고
    • Long-term continuous sildenafil treatment ameliorates corporal venocclusive dysfunction (CVOD) induced by cavernosal nerve resection in rats
    • Kovanecz I, Rambhatla A, Ferrini M, Vernet D, Sanchez S, Rajfer J, Gonalez-Cadavid N. Long-term continuous sildenafil treatment ameliorates corporal venocclusive dysfunction (CVOD) induced by cavernosal nerve resection in rats. Int J Impot Res 2008;20:202-12.
    • (2008) Int J Impot Res , vol.20 , pp. 202-212
    • Kovanecz, I.1    Rambhatla, A.2    Ferrini, M.3    Vernet, D.4    Sanchez, S.5    Rajfer, J.6    Gonalez-Cadavid, N.7
  • 7
    • 37349061006 scopus 로고    scopus 로고
    • Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction that occurs after cavernosal nerve resection
    • Kovanecz I, Rambhatla A, Ferrini MG, Vernet D, Sanchez S, Rajfer J, Gonalez-Cadavid N. Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction that occurs after cavernosal nerve resection. BJU Int 2007;101:203-10.
    • (2007) BJU Int , vol.101 , pp. 203-210
    • Kovanecz, I.1    Rambhatla, A.2    Ferrini, M.G.3    Vernet, D.4    Sanchez, S.5    Rajfer, J.6    Gonalez-Cadavid, N.7
  • 8
    • 33746808198 scopus 로고    scopus 로고
    • Vardenafil prevents fibrosis and loss of corporal smooth muscle that occurs after bilateral cavernosal nerve resection in the rat
    • Ferrini MG, Davila HH, Kovanecz I, Sanchez SP, Gonzalez-Cadavid NF, Rajfer J. Vardenafil prevents fibrosis and loss of corporal smooth muscle that occurs after bilateral cavernosal nerve resection in the rat. Urology 2006;68:429-35.
    • (2006) Urology , vol.68 , pp. 429-435
    • Ferrini, M.G.1    Davila, H.H.2    Kovanecz, I.3    Sanchez, S.P.4    Gonzalez-Cadavid, N.F.5    Rajfer, J.6
  • 10
    • 34447498964 scopus 로고    scopus 로고
    • FK506 and sildenafil promote erectile function recovery after cavernous nerve injury through antioxidative mechanisms
    • Lagoda G, Jin L, Lehrfeld TJ, Liu T, Burnett AL. FK506 and sildenafil promote erectile function recovery after cavernous nerve injury through antioxidative mechanisms. J Sex Med 2007;4:908-16.
    • (2007) J Sex Med , vol.4 , pp. 908-916
    • Lagoda, G.1    Jin, L.2    Lehrfeld, T.J.3    Liu, T.4    Burnett, A.L.5
  • 12
    • 42749093303 scopus 로고    scopus 로고
    • Chronic treatment with a type 5 phosphodiesterase inhibitor suppresses apoptosis of corporal smooth muscle by potentiating Akt signaling in a rat model of diabetic erectile dysfunction
    • Park K, Ryu KS, Li WJ, Kim SW, Paick JS. Chronic treatment with a type 5 phosphodiesterase inhibitor suppresses apoptosis of corporal smooth muscle by potentiating Akt signaling in a rat model of diabetic erectile dysfunction. Eur Urol 2008;53:1282-9.
    • (2008) Eur Urol , vol.53 , pp. 1282-1289
    • Park, K.1    Ryu, K.S.2    Li, W.J.3    Kim, S.W.4    Paick, J.S.5
  • 13
    • 44149127202 scopus 로고    scopus 로고
    • Endothelial rehabilitation: The impact of chronic PDE5 inhibitors on erectile function and protein alteration in cavernous tissue of diabetic rats
    • De Young LX, Domes T, Lim KB, Carson J, Brock GB. Endothelial rehabilitation: The impact of chronic PDE5 inhibitors on erectile function and protein alteration in cavernous tissue of diabetic rats. Eur Urol 2008;54:213-20.
    • (2008) Eur Urol , vol.54 , pp. 213-220
    • De Young, L.X.1    Domes, T.2    Lim, K.B.3    Carson, J.4    Brock, G.B.5
  • 14
    • 34548312391 scopus 로고    scopus 로고
    • Functional and morphological improvement in erectile tissue of hypertensive rats by long-term combined therapy with phosphodiesterase type 5 inhibitor and losartan
    • Toblli JE, Cao G, Lombrana A, Rivero M. Functional and morphological improvement in erectile tissue of hypertensive rats by long-term combined therapy with phosphodiesterase type 5 inhibitor and losartan. J Sex Med 2007;4:1291-303.
    • (2007) J Sex Med , vol.4 , pp. 1291-1303
    • Toblli, J.E.1    Cao, G.2    Lombrana, A.3    Rivero, M.4
  • 15
    • 16344362835 scopus 로고    scopus 로고
    • Erectile dysfunction following surgical correction of Peyronie's disease and a pilot study of the use of sildenafil citrate rehabilitation for postoperative erectile dysfunction
    • Levine LA, Greenfield JM, Estrada CR. Erectile dysfunction following surgical correction of Peyronie's disease and a pilot study of the use of sildenafil citrate rehabilitation for postoperative erectile dysfunction. J Sex Med 2005;2:241-7.
    • (2005) J Sex Med , vol.2 , pp. 241-247
    • Levine, L.A.1    Greenfield, J.M.2    Estrada, C.R.3
  • 16
    • 22144465483 scopus 로고    scopus 로고
    • The use of an erectogenic pharmacotherapy regimen following radical prostatectomy improves recovery of spontaneous erectile function
    • Mulhall JP, Land S, Parker M, Waters WB, Flanigan RC. The use of an erectogenic pharmacotherapy regimen following radical prostatectomy improves recovery of spontaneous erectile function. J Sex Med 2005;2:532-42.
    • (2005) J Sex Med , vol.2 , pp. 532-542
    • Mulhall, J.P.1    Land, S.2    Parker, M.3    Waters, W.B.4    Flanigan, R.C.5
  • 17
    • 42249094168 scopus 로고    scopus 로고
    • Recovery of erectile function after nerve sparing radical prostatectomy: Improvement with nightly low dose sildenafil
    • Bannowsky A, Schulze H, van der Horst C, Hautmann S, Junemann KP. Recovery of erectile function after nerve sparing radical prostatectomy: Improvement with nightly low dose sildenafil. BJU Int 2008;101:1279-83.
    • (2008) BJU Int , vol.101 , pp. 1279-1283
    • Bannowsky, A.1    Schulze, H.2    van der Horst, C.3    Hautmann, S.4    Junemann, K.P.5
  • 18
    • 51849117153 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of post-operative nightly sildenafil citrate for the prevention of erectile dysfunction after bilateral nerve sparing radical prostatectomy
    • Padma-Nathan H, McCullough AR, Levine LA, Lipshultz LI, Siegel R, Montorsi F, Giuliano F, Brock G, Study Group. Randomized, double-blind, placebo-controlled study of post-operative nightly sildenafil citrate for the prevention of erectile dysfunction after bilateral nerve sparing radical prostatectomy. Int J Impot Res 2008;20:479-86.
    • (2008) Int J Impot Res , vol.20 , pp. 479-486
    • Padma-Nathan, H.1    McCullough, A.R.2    Levine, L.A.3    Lipshultz, L.I.4    Siegel, R.5    Montorsi, F.6    Giuliano, F.7    Brock, G.8
  • 19
    • 50849098833 scopus 로고    scopus 로고
    • Effect of nightly versus on-demand vardenafil on recovery of erectile function in men following bilateral nerve-sparing radical prostatectomy
    • Montorsi F, Brock G, Lee J, Shapiro J, van Poppel H, Graefen M, Stief C. Effect of nightly versus on-demand vardenafil on recovery of erectile function in men following bilateral nerve-sparing radical prostatectomy. Eur Urol 2008;54:924-31.
    • (2008) Eur Urol , vol.54 , pp. 924-931
    • Montorsi, F.1    Brock, G.2    Lee, J.3    Shapiro, J.4    van Poppel, H.5    Graefen, M.6    Stief, C.7
  • 20
    • 33847362727 scopus 로고    scopus 로고
    • Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: A pilot study
    • Aversa A, Greco E, Bruzziches R, Pili M, Rosano G, Spera G. Relationship between chronic tadalafil administration and improvement of endothelial function in men with erectile dysfunction: A pilot study. Int J Impot Res 2007;19:200-7.
    • (2007) Int J Impot Res , vol.19 , pp. 200-207
    • Aversa, A.1    Greco, E.2    Bruzziches, R.3    Pili, M.4    Rosano, G.5    Spera, G.6
  • 21
    • 58849087968 scopus 로고    scopus 로고
    • Statistical evaluation of hemodynamic effects of regular use of sildenafil on the human corpora cavernosa
    • Natali A, Bartolini M, Lucarini S, Vignolini G, Nelli F, Menchi I. Statistical evaluation of hemodynamic effects of regular use of sildenafil on the human corpora cavernosa. Urol Int 2009;82:53-60.
    • (2009) Urol Int , vol.82 , pp. 53-60
    • Natali, A.1    Bartolini, M.2    Lucarini, S.3    Vignolini, G.4    Nelli, F.5    Menchi, I.6
  • 22
    • 57149111890 scopus 로고    scopus 로고
    • Serum biomarker measurements of endothelial function and oxidative stress after daily dosing of sildenafil in type 2 diabetic men with erectile dysfunction
    • Burnett AL, Strong TD, Trock BJ, Jin L, Bivalacqua TJ, Musicki B. Serum biomarker measurements of endothelial function and oxidative stress after daily dosing of sildenafil in type 2 diabetic men with erectile dysfunction. J Urol 2009;181:245-51.
    • (2009) J Urol , vol.181 , pp. 245-251
    • Burnett, A.L.1    Strong, T.D.2    Trock, B.J.3    Jin, L.4    Bivalacqua, T.J.5    Musicki, B.6
  • 23
    • 44149125039 scopus 로고    scopus 로고
    • Comparable efficacy of once-daily versus on-demand vardenafil in men with mild-to-moderate erectile dysfunction: Findings of the RESTORE study
    • Zumbe J, Porst H, Sommer F, Grohmann W, Beneke M, Ulbrich E. Comparable efficacy of once-daily versus on-demand vardenafil in men with mild-to-moderate erectile dysfunction: Findings of the RESTORE study. Eur Urol 2008;54:204-12.
    • (2008) Eur Urol , vol.54 , pp. 204-212
    • Zumbe, J.1    Porst, H.2    Sommer, F.3    Grohmann, W.4    Beneke, M.5    Ulbrich, E.6
  • 24
    • 38649122369 scopus 로고    scopus 로고
    • Return of nocturnal erections and erectile function after bilateral nerve-sparing radical prostatectomy in men treated with nightly with sildenafil citrate: Sub-analysis of a longitudinal randomized double-blind placebo-controlled trial
    • McCullough AR, Levine LA, Padma-Nathan H. Return of nocturnal erections and erectile function after bilateral nerve-sparing radical prostatectomy in men treated with nightly with sildenafil citrate: Sub-analysis of a longitudinal randomized double-blind placebo-controlled trial. J Sex Med 2008;5:476-84.
    • (2008) J Sex Med , vol.5 , pp. 476-484
    • McCullough, A.R.1    Levine, L.A.2    Padma-Nathan, H.3
  • 25
    • 33750473708 scopus 로고    scopus 로고
    • Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism
    • Burnett AL, Bivalacqua TJ, Champion HC, Musicki B. Feasibility of the use of phosphodiesterase type 5 inhibitors in a pharmacologic prevention program for recurrent priapism. J Sex Med 2006;3:1077-84.
    • (2006) J Sex Med , vol.3 , pp. 1077-1084
    • Burnett, A.L.1    Bivalacqua, T.J.2    Champion, H.C.3    Musicki, B.4
  • 26
    • 16544395184 scopus 로고    scopus 로고
    • The relationship between erectile dysfunction and lower urinary tract symptoms: Epidemiological, clinical, and basic science evidence
    • McVary KT, McKenna KE. The relationship between erectile dysfunction and lower urinary tract symptoms: Epidemiological, clinical, and basic science evidence. Curr Urol Rep 2004;5:251-7.
    • (2004) Curr Urol Rep , vol.5 , pp. 251-257
    • McVary, K.T.1    McKenna, K.E.2
  • 27
    • 58149267874 scopus 로고    scopus 로고
    • Phosphodiesterase 5 inhibitors in the management of benign prostatic hyperplasia and erectile dysfunction: The best of both worlds
    • Wong P, Lawrentschuck N, Bolton DM. Phosphodiesterase 5 inhibitors in the management of benign prostatic hyperplasia and erectile dysfunction: The best of both worlds. Curr Opin Urol 2009;19:7-12.
    • (2009) Curr Opin Urol , vol.19 , pp. 7-12
    • Wong, P.1    Lawrentschuck, N.2    Bolton, D.M.3
  • 28
    • 56449099228 scopus 로고    scopus 로고
    • The nitric oxide pathway in the human prostate: Clinical implications in men with lower urinary tract symptoms
    • Kedia GT, Uckert S, Jonas U, Kuczyk MA, Burchardt M. The nitric oxide pathway in the human prostate: Clinical implications in men with lower urinary tract symptoms. World J Urol 2008;26:603-9.
    • (2008) World J Urol , vol.26 , pp. 603-609
    • Kedia, G.T.1    Uckert, S.2    Jonas, U.3    Kuczyk, M.A.4    Burchardt, M.5
  • 30
    • 40149087543 scopus 로고    scopus 로고
    • Combination of alfuzosin and tadalafil exerts in vitro an additive relaxant effect on human corpus cavernosum
    • Oger S, Behr-Roussel D, Gorny D, Tremeaux JC, Combes M, Alexandre L, Giuliano F. Combination of alfuzosin and tadalafil exerts in vitro an additive relaxant effect on human corpus cavernosum. J Sex Med 2008;5:935-45.
    • (2008) J Sex Med , vol.5 , pp. 935-945
    • Oger, S.1    Behr-Roussel, D.2    Gorny, D.3    Tremeaux, J.C.4    Combes, M.5    Alexandre, L.6    Giuliano, F.7
  • 31
    • 67650616215 scopus 로고    scopus 로고
    • The effect of sildenafil citrate on bladder outlet obstruction: A mouse model
    • [Epub ahead of print, Dec 19]
    • Beamon CR, Mazar R, Salkini MW, Phull HS, Comiter CV. The effect of sildenafil citrate on bladder outlet obstruction: A mouse model. BJU Int 2008 [Epub ahead of print, Dec 19].
    • (2008) BJU Int 2008
    • Beamon, C.R.1    Mazar, R.2    Salkini, M.W.3    Phull, H.S.4    Comiter, C.V.5
  • 32
    • 85031356046 scopus 로고    scopus 로고
    • Effects of chronic treatment with vardenafil, a phosphodiesterase 5 inhibitor, on female rat bladder in a partial bladder outlet obstruction model
    • [Epub ahead of print, Nov 13]
    • Matsumoto S, Hanai T, Uemura H, Levin RM. Effects of chronic treatment with vardenafil, a phosphodiesterase 5 inhibitor, on female rat bladder in a partial bladder outlet obstruction model. BJU Int 2008 [Epub ahead of print, Nov 13].
    • (2008) BJU Int
    • Matsumoto, S.1    Hanai, T.2    Uemura, H.3    Levin, R.M.4
  • 33
    • 33846810223 scopus 로고    scopus 로고
    • Sildenafil citrate improves erectile function and urinary symptoms in men with erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: A randomized, double-blind trial
    • McVary KT, Monnig W, Camps JL Jr, Young JM, Tseng LJ, van den Ende G. Sildenafil citrate improves erectile function and urinary symptoms in men with erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: A randomized, double-blind trial. J Urol 2007;177:1071-7.
    • (2007) J Urol , vol.177 , pp. 1071-1077
    • McVary, K.T.1    Monnig, W.2    Camps, J.L.3    Young, J.M.4    Tseng, L.J.5    van den Ende, G.6
  • 34
    • 50949119951 scopus 로고    scopus 로고
    • Tadalafil administered once daily for Lower Urinary Tract Symptoms secondary to benign prostatic hyperplasia: A Dose Finding Study
    • Roehrborn CG, McVary KT, Elion-Mbousaa A, Viktrup L. Tadalafil administered once daily for Lower Urinary Tract Symptoms secondary to benign prostatic hyperplasia: A Dose Finding Study. J Urol 2008;180:1228-34.
    • (2008) J Urol , vol.180 , pp. 1228-1234
    • Roehrborn, C.G.1    McVary, K.T.2    Elion-Mbousaa, A.3    Viktrup, L.4
  • 35
    • 42749084255 scopus 로고    scopus 로고
    • A randomized, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia
    • Stief CG, Porst H, Neuser D, Beneke M, Ulbrich E. A randomized, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia. Eur Urol 2008;53:1236-44.
    • (2008) Eur Urol , vol.53 , pp. 1236-1244
    • Stief, C.G.1    Porst, H.2    Neuser, D.3    Beneke, M.4    Ulbrich, E.5
  • 36
    • 59349106827 scopus 로고    scopus 로고
    • Efficacy and safety of combined oral therapy with tadalafil and alfuzosin: An integrated approach to the management of patients with lower urinary tract symptoms and erectile dysfunction. Preliminary report
    • Liguori G, Trombetta C, De Giorgi G, Pomara G, Maio G, Vecchio D, Ocello G, Ollandini G, Bucci S, Belgrano E. Efficacy and safety of combined oral therapy with tadalafil and alfuzosin: An integrated approach to the management of patients with lower urinary tract symptoms and erectile dysfunction. Preliminary report. J Sex Med 2009;6:544-52.
    • (2009) J Sex Med , vol.6 , pp. 544-552
    • Liguori, G.1    Trombetta, C.2    De Giorgi, G.3    Pomara, G.4    Maio, G.5    Vecchio, D.6    Ocello, G.7    Ollandini, G.8    Bucci, S.9    Belgrano, E.10
  • 37
    • 51349092065 scopus 로고    scopus 로고
    • Comparative efficacy assessment of tamsulosin vs. tamsulosin plus tadafil in the treatment of LUTS/BPH. Pilot Study
    • Bechara A, Romano S, Casabe A, Haime S, Dedola P, Hernandez C, Rey H. Comparative efficacy assessment of tamsulosin vs. tamsulosin plus tadafil in the treatment of LUTS/BPH. Pilot Study. J Sex Med 2008;5:2170-8.
    • (2008) J Sex Med , vol.5 , pp. 2170-2178
    • Bechara, A.1    Romano, S.2    Casabe, A.3    Haime, S.4    Dedola, P.5    Hernandez, C.6    Rey, H.7
  • 38
    • 62449215028 scopus 로고    scopus 로고
    • Safety and efficacy of the simultaneous administration of udenafil and an alpha-blocker in men with erectile dysfunction concomitant with BPH/ LUTS
    • Chung BH, Lee JY, Lee SH, Yoo SJ, Lee SW, Oh CY. Safety and efficacy of the simultaneous administration of udenafil and an alpha-blocker in men with erectile dysfunction concomitant with BPH/LUTS. Int J Impot Res 2009;2:122-8.
    • (2009) Int J Impot Res , vol.2 , pp. 122-128
    • Chung, B.H.1    Lee, J.Y.2    Lee, S.H.3    Yoo, S.J.4    Lee, S.W.5    Oh, C.Y.6
  • 39
    • 0028865153 scopus 로고
    • Benign prostatic hyperplasia specific health status measures in clinical research: How much change in the American Urological Association symptom index and the benign prostatic hyperplasia impact index is perceptible to patients?
    • Barry MJ, Williford WO, Chang Y, Machi M, Jones KM, Walker-Corkery E, Lepor H. Benign prostatic hyperplasia specific health status measures in clinical research: How much change in the American Urological Association symptom index and the benign prostatic hyperplasia impact index is perceptible to patients? J Urol 1995;154:1770-4.
    • (1995) J Urol , vol.154 , pp. 1770-1774
    • Barry, M.J.1    Williford, W.O.2    Chang, Y.3    Machi, M.4    Jones, K.M.5    Walker-Corkery, E.6    Lepor, H.7
  • 40
    • 38049002372 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibitors for lower urinary tract symptoms in men
    • Gales BJ, Gales MA. Phosphodiesterase-5 inhibitors for lower urinary tract symptoms in men. Ann Pharmacother 2008;42:111-5.
    • (2008) Ann Pharmacother , vol.42 , pp. 111-115
    • Gales, B.J.1    Gales, M.A.2
  • 41
    • 56049103760 scopus 로고    scopus 로고
    • Oral phosphodiesterase type 5 inhibitors: Nonerectogenic beneficial uses
    • Mostafa T. Oral phosphodiesterase type 5 inhibitors: Nonerectogenic beneficial uses. J Sex Med 2008;5:2502-18.
    • (2008) J Sex Med , vol.5 , pp. 2502-2518
    • Mostafa, T.1
  • 44
    • 58149311195 scopus 로고    scopus 로고
    • A placebo-controlled, multicenter, randomized, double-blind, flexible-dose, two-way crossover study to evaluate the efficacy and safety of sildenafil in men with traumatic spinal cord injury and erectile dysfunction
    • Ergin S, Gunduz B, Ugurlu H, Sivrioglu K, Oncel S, Gok S, Erhan B, Levendoglu F, Senocak O. A placebo-controlled, multicenter, randomized, double-blind, flexible-dose, two-way crossover study to evaluate the efficacy and safety of sildenafil in men with traumatic spinal cord injury and erectile dysfunction. J Spinal Cord Med 2008;31:522-31.
    • (2008) J Spinal Cord Med , vol.31 , pp. 522-531
    • Ergin, S.1    Gunduz, B.2    Ugurlu, H.3    Sivrioglu, K.4    Oncel, S.5    Gok, S.6    Erhan, B.7    Levendoglu, F.8    Senocak, O.9
  • 45
    • 57149085461 scopus 로고    scopus 로고
    • Evaluation of the safety and efficacy of sildenafil citrate for erectile dysfunction in men with multiple sclerosis: A double-blind, placebo controlled, randomized study
    • Safarinejad MR. Evaluation of the safety and efficacy of sildenafil citrate for erectile dysfunction in men with multiple sclerosis: A double-blind, placebo controlled, randomized study. J Urol 2009;181:252-8.
    • (2009) J Urol , vol.181 , pp. 252-258
    • Safarinejad, M.R.1
  • 48
    • 85031365180 scopus 로고    scopus 로고
    • Cardiovascular effects of phosphodiesterase type 5 inhibitors
    • [Epub ahead of print, Dec 2]
    • Vlachopoulos C, Ioakeimidis N, Rokkas K, Stefanadis C. Cardiovascular effects of phosphodiesterase type 5 inhibitors. J Sex Med 2008 [Epub ahead of print, Dec 2].
    • (2008) J Sex Med
    • Vlachopoulos, C.1    Ioakeimidis, N.2    Rokkas, K.3    Stefanadis, C.4
  • 51
    • 67649342565 scopus 로고    scopus 로고
    • Phosphodisesterase-5 inhibitors for the treatment of Raynaud's: A novel indication
    • De LaVega AJ, Derk CT. Phosphodisesterase-5 inhibitors for the treatment of Raynaud's: A novel indication. Expert Opin Investig Drugs 2009;18:23-9.
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 23-29
    • De LaVega, A.J.1    Derk, C.T.2
  • 52
    • 85031352345 scopus 로고    scopus 로고
    • Sildenafil, an inhibitor of phosphodiesterase subtype 5, prevents indomethacin-induced small-intestinal ulceration in rats via a NO/ cGMP-dependent mechanism
    • [Epub ahead of print, Dec 20]
    • Kato N, Mashita Y, Kato S, Mitsufuji S, Yoshikawa T, Takeuchi K. Sildenafil, an inhibitor of phosphodiesterase subtype 5, prevents indomethacin-induced small-intestinal ulceration in rats via a NO/ cGMP-dependent mechanism. Dig Dis Sci 2008 [Epub ahead of print, Dec 20].
    • (2008) Dig Dis Sci
    • Kato, N.1    Mashita, Y.2    Kato, S.3    Mitsufuji, S.4    Yoshikawa, T.5    Takeuchi, K.6
  • 53
    • 85031349951 scopus 로고    scopus 로고
    • Kallianiotis. New Suspect in sports doping is, no joke, Viagra
    • November 11 Available at: (accessed January 2, 2009)
    • Niko J. Kallianiotis. New Suspect in sports doping is, no joke, Viagra. New York Times Online, November 11, 2008. Available at: http://www.nytimes.com/2008/11/23/sports/23viagra.html (accessed January 2, 2009).
    • (2008) New York Times Online
    • Niko, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.