-
1
-
-
23944468001
-
UDP-glucuronosyltransferase 2B7 is the major enzyme responsible for gemcabene glucuronidation in human liver microsomes
-
DOI 10.1124/dmd.105.005108
-
Bauman JN, Goosen TC, Tugnait M, Peterkin V, Hurst SI, Menning LC, Milad M, Court MH, and Williams JA (2005) UDP-glucuronosyltransferase 2b7 is the major enzyme responsible for gemcabene glucuronidation in human liver microsomes. Drug Metab Dispos 33:1349-1354. (Pubitemid 41196978)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.9
, pp. 1349-1354
-
-
Bauman, J.N.1
Goosen, T.C.2
Tugnait, M.3
Peterkin, V.4
Hurst, S.I.5
Menning, L.C.6
Milad, M.7
Court, M.H.8
Williams, J.A.9
-
2
-
-
0242490816
-
Pharmacotherapy for dyslipidaemia - Current therapies and future agents
-
DOI 10.1517/eoph.4.11.1901.22370
-
Bays H and Stein EA (2003) Pharmacotherapy for dyslipidaemia-current therapies and future agents. Expert Opin Pharmacother 4:1901-1938. (Pubitemid 37408104)
-
(2003)
Expert Opinion on Pharmacotherapy
, vol.4
, Issue.11
, pp. 1901-1938
-
-
Bays, H.1
Stein, E.A.2
-
3
-
-
0037370996
-
Transport of cimetidine by flounder and human renal organic anion transporter 1
-
Burckhardt BC, Brai S, Wallis S, Krick W, Wolff NA, and Burckhardt G (2003) Transport of cimetidine by flounder and human renal organic anion transporter 1. Am J Physiol Renal Physiol 284:F503-F509. (Pubitemid 36227911)
-
(2003)
American Journal of Physiology - Renal Physiology
, vol.284
, Issue.3
-
-
Burckhardt, B.C.1
Brai, S.2
Wallis, S.3
Krick, W.4
Wolff, N.A.5
Burckhardt, G.6
-
4
-
-
0035039326
-
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney
-
Cha SH, Sekine T, Fukushima JI, Kanai Y, Kobayashi Y, Goya T, and Endou H (2001) Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol Pharmacol 59:1277-1286. (Pubitemid 32385197)
-
(2001)
Molecular Pharmacology
, vol.59
, Issue.5
, pp. 1277-1286
-
-
Cha, S.H.1
Sekine, T.2
Fukushima, J.-I.3
Kanai, Y.4
Kobayashi, Y.5
Goya, T.6
Endou, H.7
-
6
-
-
0035066252
-
Transporters involved in the elimination of drugs in the kidney: Organic anion transporters and organic cation transporters
-
DOI 10.1002/1520-6017(200104)90:4<397::AID-JPS1000>3.0.CO;2-D
-
Dresser MJ, Leabman MK, and Giacomini KM (2001) Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters. J Pharm Sci 90:397-421. (Pubitemid 32298045)
-
(2001)
Journal of Pharmaceutical Sciences
, vol.90
, Issue.4
, pp. 397-421
-
-
Dresser, M.J.1
Leabman, M.K.2
Giacomini, K.M.3
-
7
-
-
40949148698
-
Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: An in vitro-in vivo study
-
Feng B, Obach RS, Burstein AH, Clark DJ, de Morais SM, and Faessel HM (2008) Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study. Clin Pharmacol Ther 83:567-576.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 567-576
-
-
Feng, B.1
Obach, R.S.2
Burstein, A.H.3
Clark, D.J.4
De Morais, S.M.5
Faessel, H.M.6
-
8
-
-
0036175127
-
Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions
-
DOI 10.1124/jpet.300.3.746
-
Hasegawa M, Kusuhara H, Sugiyama D, Ito K, Ueda S, Endou H, and Sugiyama Y (2002) Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. J Pharmacol Exp Ther 300:746-753. (Pubitemid 34164975)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.300
, Issue.3
, pp. 746-753
-
-
Maki, H.1
Kusuhara, H.2
Sugiyama, D.3
Ito, K.4
Ueda, S.5
Endou, H.6
Sugiyama, Y.7
-
9
-
-
0024550232
-
Quinapril - A preclinical review of the pharmacology, pharmacokinetics, and toxicology
-
Kaplan HR, Taylor DG, Olson SC, and Andrews LK (1989) Quinapril-a preclinical review of the pharmacology, pharmacokinetics, and toxicology. Angiology 40:335-350. (Pubitemid 19108868)
-
(1989)
Angiology
, vol.40
, Issue.4
, pp. 335-350
-
-
Kaplan, H.R.1
Taylor, D.G.2
Olson, S.C.3
Andrews, L.K.4
-
10
-
-
0029585850
-
Disposition of quinapril and quinaprilat in the isolated perfused rat kidney
-
Kugler AR, Olson SC, and Smith DE (1995) Disposition of quinapril and quinaprilat in the isolated perfused rat kidney. J Pharmacokinet Biopharm 23:287-305.
-
(1995)
J Pharmacokinet Biopharm
, vol.23
, pp. 287-305
-
-
Kugler, A.R.1
Olson, S.C.2
Smith, D.E.3
-
11
-
-
0030513880
-
Tubular transport mechanisms of quinapril and quinaprilat in the isolated perfused rat kidney: Effect of organic anions and cations
-
Kugler AR, Olson SC, and Smith DE (1996) Tubular transport mechanisms of quinapril and quinaprilat in the isolated perfused rat kidney: effect of organic anions and cations. J Pharmacokinet Biopharm 24:349-368.
-
(1996)
J Pharmacokinet Biopharm
, vol.24
, pp. 349-368
-
-
Kugler, A.R.1
Olson, S.C.2
Smith, D.E.3
-
12
-
-
34147133352
-
Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans
-
DOI 10.1080/00498250601188808, PII 777020814
-
Nakagomi-Hagihara R, Nakai D, and Tokui T (2007) Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans. Xenobiotica 37:416-426. (Pubitemid 46572887)
-
(2007)
Xenobiotica
, vol.37
, Issue.4
, pp. 416-426
-
-
Nakagomi-Hagihara, R.1
Nakai, D.2
Tokui, T.3
-
13
-
-
0024536336
-
The clinical pharmacokinetics of quinapril
-
Olson SC, Horvath AM, Michniewicz BM, Sedman AJ, Colburn WA, and Welling PG (1989) The clinical pharmacokinetics of quinapril. Angiology 40:351-359.
-
(1989)
Angiology
, vol.40
, pp. 351-359
-
-
Olson, S.C.1
Horvath, A.M.2
Michniewicz, B.M.3
Sedman, A.J.4
Colburn, W.A.5
Welling, P.G.6
-
14
-
-
0033574034
-
Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)
-
DOI 10.1006/bbrc.1998.9978
-
Race JE, Grassl SM, Williams WJ, and Holtzman EJ (1999) Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem Biophys Res Commun 255:508-514. (Pubitemid 29292290)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.255
, Issue.2
, pp. 508-514
-
-
Race, J.E.1
Grassl, S.M.2
Williams, W.J.3
Holtzman, E.J.4
-
15
-
-
33645798634
-
Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid
-
Tahara H, Kusuhara H, Maeda K, Koepsell H, Fuse E, and Sugiyama Y (2006) Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid. Drug Metab Dispos 34:743-747.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 743-747
-
-
Tahara, H.1
Kusuhara, H.2
Maeda, K.3
Koepsell, H.4
Fuse, E.5
Sugiyama, Y.6
-
16
-
-
0032979273
-
Immunohistochemical localization of multispecific renal organic anion transporter 1 in rat kidney
-
Tojo A, Sekine T, Nakajima N, Hosoyamada M, Kanai Y, Kimura K, and Endou H (1999) Immunohistochemical localization of multispecific renal organic anion transporter 1 in rat kidney. J Am Soc Nephrol 10:464-471. (Pubitemid 29117627)
-
(1999)
Journal of the American Society of Nephrology
, vol.10
, Issue.3
, pp. 464-471
-
-
Tojo, A.1
Sekine, T.2
Nakajima, N.3
Hosoyamada, M.4
Kanai, Y.5
Kimura, K.6
Endou, H.7
-
17
-
-
0031768564
-
Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney
-
DOI 10.1016/S0014-5793(98)01328-3, PII S0014579398013283
-
Uwai Y, Okuda M, Takami K, Hashimoto Y, and Inui K (1998) Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney. FEBS Lett 438:321-324. (Pubitemid 28529298)
-
(1998)
FEBS Letters
, vol.438
, Issue.3
, pp. 321-324
-
-
Uwai, Y.1
Okuda, M.2
Takami, K.3
Hashimoto, Y.4
Inui, K.-I.5
-
18
-
-
0034560136
-
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter
-
DOI 10.1016/S0014-2999(00)00837-2, PII S0014299900008372
-
Uwai Y, Saito H, and Inui K (2000) Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter. Eur J Pharmacol 409:31-36. (Pubitemid 30950633)
-
(2000)
European Journal of Pharmacology
, vol.409
, Issue.1
, pp. 31-36
-
-
Uwai, Y.1
Saito, H.2
Inui, K.-I.3
-
19
-
-
0025959405
-
Quinapril: A review of its pharmacological properties, and therapeutic efficacy in cardiovascular disorders
-
Wadworth AN and Brogden RN (1991) Quinapril. A review of its pharmacological properties, and therapeutic efficacy in cardiovascular disorders. Drugs 41:378-399. (Pubitemid 21920735)
-
(1991)
Drugs
, vol.41
, Issue.3
, pp. 378-399
-
-
Wadworth, A.N.1
Brogden, R.N.2
-
20
-
-
3042542425
-
Molecular and cellular physiology of renal organic cation and anion transport
-
DOI 10.1152/physrev.00040.2003
-
Wright SH and Dantzler WH (2004) Molecular and cellular physiology of renal organic cation and anion transport. Physiol Rev 84:987-1049. (Pubitemid 38823772)
-
(2004)
Physiological Reviews
, vol.84
, Issue.3
, pp. 987-1049
-
-
Wright, S.H.1
Dantzler, W.H.2
|