Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation

Free Radical Biology and Medicine

Volumn 47, Issue 4, 2009, Pages 389-400

  Kennett, Eleanor C ^a   Davies, Michael J ^a,b  

^a HEART RESEARCH INSTITUTE   (Australia)

^b University of Sydney   (Australia)

Author keywords

Carbonate radical; Chondroitin sulfate; EPR; Extracellular matrix; Free radicals; Glycosaminoglycans; Hyaluronan; Hydroxyl radical; Nitrogen dioxide radical; Peroxynitrite

Indexed keywords

CARBON 13; CARBONIC ACID; CHONDROITIN SULFATE; DISACCHARIDE; GLYCOSAMINOGLYCAN; HYALURONIC ACID; HYDROXYL RADICAL; MONOSACCHARIDE; NITROGEN DIOXIDE; OLIGOMER; OXYGEN; PEROXYNITRITE; POLYMER;

ARTICLE; CARBOHYDRATE ANALYSIS; DEPOLYMERIZATION; INFLAMMATION; PRIORITY JOURNAL;

CARBON RADIOISOTOPES; CARBONATES; CHONDROITIN SULFATES; ELECTRON SPIN RESONANCE SPECTROSCOPY; EXTRACELLULAR MATRIX; FREE RADICALS; GLYCOCALYX; GLYCOSAMINOGLYCANS; HUMANS; HYALURONIC ACID; HYDROXYL RADICAL; INFLAMMATION; NITROGEN DIOXIDE; OXIDATIVE STRESS; PEROXYNITROUS ACID; POLYMERS; SYNOVIAL FLUID;

EID: 67649881104     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.05.002     Document Type: Article

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