Detection of a stable nitroxide during chemical depolymerization of heparin

Research on Chemical Intermediates

Volumn 32, Issue 1, 2006, Pages 73-81

  Rota, Cristina ^a   Liverani, Lino ^b   Spelta, Franco ^b   Mascellani, Giuseppe ^b   Tomasi, Aldo ^a   Iannone, Anna ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b Opocrin SpA   (Italy)

Author keywords

ESR; Free radical; Heparin; Nitroxide

Indexed keywords

COPPER; DEPOLYMERIZATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; HYDROGEN PEROXIDE; MOLECULAR WEIGHT; PLASMAS;

HEPARIN; LOW MOLECULAR WEIGHT HEPARINS (LMWH); NITROXIDE; UNFRACTIONATED HEPARIN (UFH);

NITROGEN OXIDES;

EID: 32944469354     PISSN: 09226168     EISSN: None     Source Type: Journal    
DOI: 10.1163/156856706775012932     Document Type: Article

References (19)

1. B. Casu, in: Heparin, Chemical and Biological Properties. Clinical Application, D. A. Lane and U. Lindahl (Eds), p. 25. Edward Arnold, London (1989).
2. J. Hirsh, N. Engl. J. Med. 324, 1565 (1991).
3. T. Barzu, P. Molho, G. Tobelem, M. Petitou and J. Caen, Biochim. Biophys. Acta 845, 196 (1985).
4. B. Boneu, C. Caranobe, Y. Cadroy, F. Dol, A. M. Gabaig, D. Dupouy and P. Sie, Semin. Thromb. Hemost. 14, 18 (1988).
5. J. Hirsh, T. E. Warkentin, R. Raschke, C. Granger, E. M. Ohman and J. E. Dalen, Chest 114, 489S (1998).
6. M. A. Quader, L. S. Stump and B. E. Sumpio, J. Am. Coll. Surg. 187, 641 (1998).
7. K. T. Kruse-Elliott, K. Chaban, J. E. Grossman, S. Tomasko, C. Kamke and B. Darien, Shock 10, 198 (1998).
8. D. Green, R. D. Hull, R. Brant and G. F. Pineo, Lancet 339, 1476 (1992).
9. J. Folkman, R. Langer, R. J. Linhardt, C. Haudenschild and S. Taylor, Science 221, 719 (1983).
10. Z. Liu and A. S. Perlin, Carbohydr. Res. 255, 183 (1994).
11. E. Holmer, in: Heparin, Chemical and Biological Properties. Clinical Application, D. A. Lane and U. Lindahl (Eds), p. 575. Edward Arnold, London (1989).
12. G. Mascellani and P. Bianchini, European Patent 221,997 B1 (1986).
13. P. Bianchini and G. Mascellani, US Patent No. 4,791,195 (1986).
14. P. Bianchini and G. Mascellani, US Patent No. 4,933,326 (1988).
15. N. Volpi, G. Mascellani and P. Bianchini, Anal. Biochem. 200, 100 (1992).
16. W. Jeske, O. Iqbal, S. Gonnela, G. Boveri, G. Torri, L. De Ambrosi and J. Fareed, Semin. Thromb. Hemost. 21, 201 (1995).
17. R. P. Mason, F. J. Peterson and J. L. Holtzman, Biochem. Biophys. Res. Commun. 75, 532 (1977).
18. D. C. Borg, in: Free Radicals in Biology, Volume 1, W. A. Pryor (Ed.), p. 69. Academic Press, New York, NY (1976).
19. D. R. Duling, J. Magn. Reson. B 104, 105 (1994).